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Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-26259-y
By:
- Jin, Haihong;
- Ladd, Nicole A.;
- Peev, Andrew M.;
- Swarbrick, Gwendolyn M.;
- Cansler, Meghan;
- Null, Megan;
- Boughter, Christopher T.;
- McMurtrey, Curtis;
- Nilsen, Aaron;
- Dobos, Karen M.;
- Hildebrand, William H.;
- Lewinsohn, Deborah A.;
- Adams, Erin J.;
- Lewinsohn, David M.;
- Harriff, Melanie J.
Publication type:
Article
Comprehensive definition of human immunodominant CD8 antigens in tuberculosis.
Published in:
NPJ Vaccines, 2017, v. 2, n. 1, p. N.PAG, doi. 10.1038/s41541-017-0008-6
By:
- Lewinsohn, Deborah A.;
- Swarbrick, Gwendolyn M.;
- Park, Byung;
- Cansler, Meghan E.;
- Null, Megan D.;
- Toren, Katelynne G.;
- Baseke, Joy;
- Zalwango, Sarah;
- Mayanja-Kizza, Harriet;
- Malone, LaShaunda L.;
- Nyendak, Melissa;
- Wu, Guanming;
- Guinn, Kristi;
- McWeeney, Shannon;
- Mori, Tomi;
- Chervenak, Keith A.;
- Sherman, David R.;
- Boom, W. Henry;
- Lewinsohn, David M.
Publication type:
Article
Adenovirally-Induced Polyfunctional T Cells Do Not Necessarily Recognize the Infected Target: Lessons from a Phase I Trial of the AERAS-402 Vaccine.
Published in:
Scientific Reports, 2016, p. 36355, doi. 10.1038/srep36355
By:
- Nyendak, Melissa;
- Swarbrick, Gwendolyn M.;
- Duncan, Amanda;
- Cansler, Meghan;
- Huff, Ervina Winata;
- Hokey, David;
- Evans, Tom;
- Barker, Lewellys;
- Blatner, Gretta;
- Sadoff, Jerald;
- Douoguih, Macaya;
- Pau, Maria Grazia;
- Lewinsohn, Deborah A.;
- Lewinsohn, David M.
Publication type:
Article
Mycobacterium tuberculosis Specific CD8+ T Cells Rapidly Decline with Antituberculosis Treatment.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0081564
By:
- Nyendak, Melissa R.;
- Park, Byung;
- Null, Megan D.;
- Baseke, Joy;
- Swarbrick, Gwendolyn;
- Mayanja-Kizza, Harriet;
- Nsereko, Mary;
- Johnson, Denise F.;
- Gitta, Phineas;
- Okwera, Alphonse;
- Goldberg, Stefan;
- Bozeman, Lorna;
- Johnson, John L.;
- Boom, W. Henry;
- Lewinsohn, Deborah A.;
- Lewinsohn, David M.
Publication type:
Article
Human Mycobacterium tuberculosis CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067016
By:
- Lewinsohn, David M.;
- Swarbrick, Gwendolyn M.;
- Cansler, Meghan E.;
- Null, Megan D.;
- Rajaraman, Veena;
- Frieder, Marisa M.;
- Sherman, David R.;
- McWeeney, Shannon;
- Lewinsohn, Deborah A.
Publication type:
Article
A-Kinase Anchoring in Dendritic Cells Is Required for Antigen Presentation.
Published in:
PLoS ONE, 2009, v. 4, n. 3, p. 1, doi. 10.1371/journal.pone.0004807
By:
- Schillace, Robynn V.;
- Miller, Casey L.;
- Pisenti, Neal;
- Grotzke, Jeff E.;
- Swarbrick, Gwendolyn M.;
- Lewinsohn, David M.;
- Carr, Daniel W.
Publication type:
Article
Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B.
Published in:
PLoS Pathogens, 2007, v. 3, n. 9, p. 1240, doi. 10.1371/journal.ppat.0030127
By:
- Lewinsohn, Deborah A.;
- Winata, Ervina;
- Swarbrick, Gwendolyn M.;
- Tanner, Katie E.;
- Cook, Matthew S.;
- Null, Megan D.;
- Cansler, Meghan E.;
- Sette, Alessandro;
- Sidney, John;
- Lewinsohn, David M.
Publication type:
Article
MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage.
Published in:
Science Immunology, 2018, v. 3, n. 25, p. 1, doi. 10.1126/sciimmunol.aao2556
By:
- Harriff, Melanie J.;
- McMurtrey, Curtis;
- Froyd, Cara A.;
- Haihong Jin;
- Cansler, Meghan;
- Null, Megan;
- Worley, Aneta;
- Meermeier, Erin W.;
- Swarbrick, Gwendolyn;
- Nilsen, Aaron;
- Lewinsohn, Deborah A.;
- Hildebrand, William;
- Adams, Erin J.;
- Lewinsohn, David M.
Publication type:
Article
Production of Proinflammatory Cytokines by CD4+ and CD8+ T Cells in Response to Mycobacterial Antigens among Children and Adults with Tuberculosis.
Published in:
Pathogens, 2023, v. 12, n. 11, p. 1353, doi. 10.3390/pathogens12111353
By:
- Morrow, Erin;
- Liu, Qijia;
- Kiguli, Sarah;
- Swarbrick, Gwendolyn;
- Nsereko, Mary;
- Null, Megan D.;
- Cansler, Meghan;
- Mayanja-Kizza, Harriet;
- Boom, W. Henry;
- Chheng, Phalkun;
- Nyendak, Melissa R.;
- Lewinsohn, David M.;
- Lewinsohn, Deborah A.;
- Lancioni, Christina L.
Publication type:
Article
Postnatal Expansion, Maturation, and Functionality of MR1T Cells in Humans.
Published in:
Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.556695
By:
- Swarbrick, Gwendolyn M.;
- Gela, Anele;
- Cansler, Meghan E.;
- Null, Megan D.;
- Duncan, Rowan B.;
- Nemes, Elisa;
- Shey, Muki;
- Nsereko, Mary;
- Mayanja-Kizza, Harriet;
- Kiguli, Sarah;
- Koh, Jeffrey;
- Hanekom, Willem A.;
- Hatherill, Mark;
- Lancioni, Christina;
- Lewinsohn, David M.;
- Scriba, Thomas J.;
- Lewinsohn, Deborah A.
Publication type:
Article
CD8+ T Cells Provide an Immunologic Signature of Tuberculosis in Young Children.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2012, v. 185, n. 2, p. 206, doi. 10.1164/rccm.201107-1355OC
By:
- Lancioni, Christina;
- Nyendak, Melissa;
- Kiguli, Sarah;
- Zalwango, Sarah;
- Mori, Tomi;
- Mayanja-Kizza, Harriet;
- Balyejusa, Stephen;
- Null, Megan;
- Baseke, Joy;
- Mulindwa, Deo;
- Byrd, Laura;
- Swarbrick, Gwendolyn;
- Scott, Christine;
- Johnson, Denise F.;
- Malone, LaShaunda;
- Mudido-Musoke, Philipa;
- Boom, W. Henry;
- Lewinsohn, David M.;
- Lewinsohn, Deborah A.
Publication type:
Article
Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells.
Published in:
PLoS Biology, 2010, v. 8, n. 6, p. 1, doi. 10.1371/journal.pbio.1000407
By:
- Gold, Marielle C.;
- Cerri, Stefania;
- Smyk-Pearson, Susan;
- Cansler, Meghan E.;
- Vogt, Todd M.;
- Delepine, Jacob;
- Winata, Ervina;
- Swarbrick, Gwendolyn M.;
- Wei-Jen Chua;
- Yu, Yik Y. L.;
- Lantz, Olivier;
- Cook, Matthew S.;
- Null, Megan D.;
- Jacoby, David B.;
- Harriff, Melanie J.;
- Lewinsohn3,6, Deborah A.;
- Hansen, Ted H.;
- Lewinsohn, David M.
Publication type:
Article
The MAIT TCRβ chain contributes to discrimination of microbial ligand.
Published in:
Immunology & Cell Biology, 2020, v. 98, n. 9, p. 770, doi. 10.1111/imcb.12370
By:
- Narayanan, Gitanjali A;
- McLaren, James E;
- Meermeier, Erin W;
- Ladell, Kristin;
- Swarbrick, Gwendolyn M;
- Price, David A;
- Tran, Jessica G;
- Worley, Aneta H;
- Vogt, Todd;
- Wong, Emily B;
- Lewinsohn, David M
Publication type:
Article
Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation.
Published in:
Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-05912-4
By:
- Kulicke, Corinna A.;
- Swarbrick, Gwendolyn M.;
- Ladd, Nicole A.;
- Cansler, Meghan;
- Null, Megan;
- Worley, Aneta;
- Lemon, Chance;
- Ahmed, Tania;
- Bennett, Joshua;
- Lust, Taylor N.;
- Heisler, Chelsea M.;
- Huber, Megan E.;
- Krawic, Jason R.;
- Ankley, Laurisa M.;
- McBride, Savannah K.;
- Tafesse, Fikadu G.;
- Olive, Andrew J.;
- Hildebrand, William H.;
- Lewinsohn, Deborah A.;
- Adams, Erin J.
Publication type:
Article
Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03823-w
By:
- Meermeier, Erin W.;
- Zheng, Christina L.;
- Tran, Jessica G.;
- Soma, Shogo;
- Worley, Aneta H.;
- Weiss, David I.;
- Modlin, Robert L.;
- Swarbrick, Gwendolyn;
- Karamooz, Elham;
- Khuzwayo, Sharon;
- Wong, Emily B.;
- Gold, Marielle C.;
- Lewinsohn, David M.
Publication type:
Article
Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03823-w
By:
- Meermeier, Erin W.;
- Zheng, Christina L.;
- Tran, Jessica G.;
- Soma, Shogo;
- Worley, Aneta H.;
- Weiss, David I.;
- Modlin, Robert L.;
- Swarbrick, Gwendolyn;
- Karamooz, Elham;
- Khuzwayo, Sharon;
- Wong, Emily B.;
- Gold, Marielle C.;
- Lewinsohn, David M.
Publication type:
Article
T cell recognition of Mycobacterium tuberculosis peptides presented by HLA-E derived from infected human cells.
Published in:
PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0188288
By:
- McMurtrey, Curtis;
- Harriff, Melanie J.;
- Swarbrick, Gwendolyn M.;
- Duncan, Amanda;
- Cansler, Meghan;
- Null, Megan;
- Bardet, Wilfried;
- Jackson, Kenneth W.;
- Lewinsohn, Deborah A.;
- Hildebrand, William;
- Lewinsohn, David M.
Publication type:
Article

Found: 17

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells.

Comprehensive definition of human immunodominant CD8 antigens in tuberculosis.

Adenovirally-Induced Polyfunctional T Cells Do Not Necessarily Recognize the Infected Target: Lessons from a Phase I Trial of the AERAS-402 Vaccine.

<i>Mycobacterium tuberculosis</i> Specific CD8<sup>+</sup> T Cells Rapidly Decline with Antituberculosis Treatment.

Human <i>Mycobacterium tuberculosis</i> CD8 T Cell Antigens/Epitopes Identified by a Proteomic Peptide Library.

A-Kinase Anchoring in Dendritic Cells Is Required for Antigen Presentation.

Immunodominant Tuberculosis CD8 Antigens Preferentially Restricted by HLA-B.

MR1 displays the microbial metabolome driving selective MR1-restricted T cell receptor usage.

Production of Proinflammatory Cytokines by CD4+ and CD8+ T Cells in Response to Mycobacterial Antigens among Children and Adults with Tuberculosis.

Postnatal Expansion, Maturation, and Functionality of MR1T Cells in Humans.

CD8<sup>+</sup> T Cells Provide an Immunologic Signature of Tuberculosis in Young Children.

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells.

The MAIT TCRβ chain contributes to discrimination of microbial ligand.

Delivery of loaded MR1 monomer results in efficient ligand exchange to host MR1 and subsequent MR1T cell activation.

Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive.

Human lung-resident mucosal-associated invariant T cells are abundant, express antimicrobial proteins, and are cytokine responsive.

T cell recognition of Mycobacterium tuberculosis peptides presented by HLA-E derived from infected human cells.