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Hochdurchsatzstrategien zur Entdeckung und Optimierung katalytischer Reaktionen.
Published in:
Angewandte Chemie, 2019, v. 131, n. 22, p. 7254, doi. 10.1002/ange.201812534
By:
- Isbrandt, Eric S.;
- Sullivan, Ryan J.;
- Newman, Stephen G.
Publication type:
Article
Phase 1b study of intravenous coxsackievirus A21 (V937) and ipilimumab for patients with metastatic uveal melanoma.
Published in:
Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 9, p. 6059, doi. 10.1007/s00432-022-04510-3
By:
- Lutzky, Jose;
- Sullivan, Ryan J.;
- Cohen, Justine V.;
- Ren, Yixin;
- Li, Anlong;
- Haq, Rizwan
Publication type:
Article
Editorial: Toxicity mechanism and clinical features of PD-1/ PD-l1 inhibitors in treatment of cancer, volume II.
Published in:
Frontiers in Pharmacology, 2023, v. 14, p. 1, doi. 10.3389/fphar.2023.1136373
By:
- Chuqi Lei;
- Xiangyi Kong;
- Sullivan, Ryan J.;
- Caisheng Wu;
- Dawei Wang;
- Lin Zhang
Publication type:
Article
Editorial: Toxicity Mechanism and Clinical Features of PD-1/PD-L1 Inhibitors in Treatment of Cancer, Volume I.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.898368
By:
- Kong, Xiangyi;
- Sullivan, Ryan J;
- Wu, Caisheng;
- Zhang, Lin;
- Jiang, Yu
Publication type:
Article
Combination therapies to inhibit the RAF/MEK/ERK pathway in melanoma: we are not done yet.
Published in:
Frontiers in Oncology, 2015, p. 1, doi. 10.3389/fonc.2015.00161
By:
- McArthur, Grant A.;
- Sullivan, Ryan J.;
- Lito, Piro;
- Smalley, Keiran
Publication type:
Article
When is it OK to Stop Anti-Programmed Death 1 Receptor (PD-1) Therapy in Metastatic Melanoma?
Published in:
American Journal of Clinical Dermatology, 2020, v. 21, n. 3, p. 313, doi. 10.1007/s40257-020-00506-2
By:
- Banks, Lauren B.;
- Sullivan, Ryan J.
Publication type:
Article
Mechanisms of Resistance to Immune Checkpoint Blockade.
Published in:
American Journal of Clinical Dermatology, 2019, v. 20, n. 1, p. 41, doi. 10.1007/s40257-018-0389-y
By:
- Sullivan, Ryan J.;
- Liu, David;
- Jenkins, Russell W.
Publication type:
Article
Co‐targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor‐resistant melanoma.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 5, p. 1, doi. 10.15252/emmm.201708446
By:
- Echevarría‐Vargas, Ileabett M.;
- Reyes‐Uribe, Patricia I.;
- Guterres, Adam N.;
- Yin, Xiangfan;
- Kossenkov, Andrew V.;
- Liu, Qin;
- Zhang, Gao;
- Krepler, Clemens;
- Cheng, Chaoran;
- Wei, Zhi;
- Somasundaram, Rajasekharan;
- Karakousis, Giorgos;
- Xu, Wei;
- Morrissette, Jennifer J. D.;
- Lu, Yiling;
- Mills, Gordon B.;
- Sullivan, Ryan J.;
- Benchun, Miao;
- Frederick, Dennie T.;
- Boland, Genevieve
Publication type:
Article
Cytokine therapy in melanoma.
Published in:
Journal of Cutaneous Pathology, 2010, v. 37, p. 60, doi. 10.1111/j.1600-0560.2010.01507.x
By:
- Sullivan, Ryan J.;
- Atkins, Michael B.
Publication type:
Article
Toxicities from BRAF and MEK Inhibitors: Strategies to Maximize Therapeutic Success.
Published in:
Current Oncology Reports, 2024, v. 26, n. 8, p. 934, doi. 10.1007/s11912-024-01544-3
By:
- Wang, Mike;
- Sullivan, Ryan J.;
- Mooradian, Meghan J
Publication type:
Article
Acute and chronic kidney function decline in patients receiving BRAF/MEK inhibitors for melanoma.
Published in:
Nephrology Dialysis Transplantation, 2024, v. 39, n. 6, p. 1040, doi. 10.1093/ndt/gfae049
By:
- Mistry, Kavita;
- Zhao, Sophia;
- Strohbehn, Ian;
- Wang, Qiyu;
- Hanna, Paul;
- Strohbehn, Samuel;
- Katz-Agranov, Nurit;
- Sullivan, Ryan J;
- Sise, Meghan E
Publication type:
Article
Clinical features of acute kidney injury in patients receiving dabrafenib and trametinib.
Published in:
Nephrology Dialysis Transplantation, 2022, v. 37, n. 3, p. 507, doi. 10.1093/ndt/gfaa372
By:
- Seethapathy, Harish;
- Lee, Meghan D;
- Strohbehn, Ian A;
- Efe, Orhan;
- Rusibamayila, Nifasha;
- Chute, Donald F;
- Colvin, Robert B;
- Rosales, Ivy A;
- Fadden, Riley M;
- Reynolds, Kerry L;
- Sullivan, Ryan J;
- Kaufman, Howard L;
- Jhaveri, Kenar D;
- Sise, Meghan E
Publication type:
Article
STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29541-9
By:
- Chu, Zhaowei;
- Gu, Lei;
- Hu, Yeguang;
- Zhang, Xiaoyang;
- Li, Man;
- Chen, Jiajia;
- Teng, Da;
- Huang, Man;
- Shen, Che-Hung;
- Cai, Li;
- Yoshida, Toshimi;
- Qi, Yifeng;
- Niu, Zhixin;
- Feng, Austin;
- Geng, Songmei;
- Frederick, Dennie T.;
- Specht, Emma;
- Piris, Adriano;
- Sullivan, Ryan J.;
- Flaherty, Keith T.
Publication type:
Article
Pathway signatures derived from on-treatment tumor specimens predict response to anti-PD1 blockade in metastatic melanoma.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26299-4
By:
- Du, Kuang;
- Wei, Shiyou;
- Wei, Zhi;
- Frederick, Dennie T.;
- Miao, Benchun;
- Moll, Tabea;
- Tian, Tian;
- Sugarman, Eric;
- Gabrilovich, Dmitry I.;
- Sullivan, Ryan J.;
- Liu, Lunxu;
- Flaherty, Keith T.;
- Boland, Genevieve M.;
- Herlyn, Meenhard;
- Zhang, Gao
Publication type:
Article
The "Great Debate" at Immunotherapy Bridge 2022, Naples, November 30th–December 1st, 2022.
Published in:
Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04117-3
By:
- Ascierto, Paolo A.;
- Brentjens, Renier;
- Khleif, Samir N.;
- Odunsi, Kunle;
- Rezvani, Katayoun;
- Ruella, Marco;
- Sullivan, Ryan J.;
- Fox, Bernard A.;
- Puzanov, Igor
Publication type:
Article
Targeting wild-type TP53 using AMG 232 in combination with MAPK inhibition in Metastatic Melanoma; a phase 1 study.
Published in:
Investigational New Drugs, 2022, v. 40, n. 5, p. 1051, doi. 10.1007/s10637-022-01253-3
By:
- Moschos, Stergios J.;
- Sandhu, Shahneen;
- Lewis, Karl D.;
- Sullivan, Ryan J.;
- Puzanov, Igor;
- Johnson, Douglas B.;
- Henary, Haby A.;
- Wong, Hansen;
- Upreti, Vijay V.;
- Long, Georgina V.;
- Flaherty, Keith T.
Publication type:
Article
BRAF in Melanoma: Pathogenesis, Diagnosis, Inhibition, and Resistance.
Published in:
Journal of Skin Cancer, 2011, p. 1, doi. 10.1155/2011/423239
By:
- Sullivan, Ryan J.;
- Flaherty, Keith T.
Publication type:
Article
Clinical Profiling of BCL-2 Family Members in the Setting of BRAF Inhibition Offers a Rationale for Targeting De Novo Resistance Using BH3 Mimetics.
Published in:
PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0101286
By:
- Frederick, Dennie T.;
- Salas Fragomeni, Roberto A.;
- Schalck, Aislyn;
- Ferreiro-Neira, Isabel;
- Hoff, Taylor;
- Cooper, Zachary A.;
- Haq, Rizwan;
- Panka, David J.;
- Kwong, Lawrence N.;
- Davies, Michael A.;
- Cusack, James C.;
- Flaherty, Keith T.;
- Fisher, David E.;
- Mier, James W.;
- Wargo, Jennifer A.;
- Sullivan, Ryan J.
Publication type:
Article
Cardiovascular magnetic resonance in immune checkpoint inhibitor-associated myocarditis.
Published in:
European Heart Journal, 2020, v. 41, n. 18, p. 1733, doi. 10.1093/eurheartj/ehaa051
By:
- Zhang, Lili;
- Awadalla, Magid;
- Mahmood, Syed S;
- Nohria, Anju;
- Hassan, Malek Z O;
- Thuny, Franck;
- Zlotoff, Daniel A;
- Murphy, Sean P;
- Stone, James R;
- Golden, Doll Lauren Alexandra;
- Alvi, Raza M;
- Rokicki, Adam;
- Jones-O'Connor, Maeve;
- Cohen, Justine V;
- Heinzerling, Lucie M;
- Mulligan, Connor;
- Armanious, Merna;
- Barac, Ana;
- Forrestal, Brian J;
- Sullivan, Ryan J
Publication type:
Article
What to Do When Anti-PD-1 Therapy Fails in Patients With Melanoma.
Published in:
Oncology (08909091), 2019, v. 33, n. 4, p. 141
By:
- Mooradian, Meghan J.;
- Sullivan, Ryan J.
Publication type:
Article
Optimal Treatment Selection for Patients With Metastatic Melanoma.
Published in:
2015
By:
- Sullivan, Ryan J.
Publication type:
Journal Article
Optimal Treatment Selection for Patients With Metastatic Melanoma.
Published in:
Oncology (08909091), 2015, v. 29, n. 2, p. 1
By:
- Sullivan, Ryan J.
Publication type:
Article
Circulating BRAFV600E Levels Correlate with Treatment in Patients with Thyroid Carcinoma.
Published in:
Thyroid, 2018, v. 28, n. 3, p. 328, doi. 10.1089/thy.2017.0322
By:
- Lubitz, Carrie C.;
- Tiannan Zhan;
- Gunda, Viswanath;
- Amin, Salma;
- Gigliotti, Benjamin J.;
- Fingeret, Abbey L.;
- Holm, Tammy M.;
- Wachtel, Heather;
- Sadow, Peter M.;
- Wirth, Lori J.;
- Sullivan, Ryan J.;
- Panka, David J.;
- Parangi, Sareh
Publication type:
Article
Immunotherapy in Melanoma: Recent Advancements and Future Directions.
Published in:
Cancers, 2023, v. 15, n. 16, p. 4176, doi. 10.3390/cancers15164176
By:
- Mooradian, Meghan J.;
- Sullivan, Ryan J.
Publication type:
Article
The Role of Triple Therapy in BRAF-Positive Melanoma.
Published in:
Clinical Advances in Hematology & Oncology, 2022, v. 20, n. 6, p. 359
By:
- Sullivan, Ryan J.
Publication type:
Article
The Future of Combination Treatment With Checkpoint Inhibitors in Melanoma.
Published in:
Clinical Advances in Hematology & Oncology, 2019, v. 17, n. 2, p. 96
By:
- Sullivan, Ryan J.
Publication type:
Article
Hypophysitis secondary to nivolumab and pembrolizumab is a clinical entity distinct from ipilimumab-associated hypophysitis.
Published in:
European Journal of Endocrinology, 2019, v. 181, n. 3, p. 211, doi. 10.1530/EJE-19-0238
By:
- Faje, Alexander;
- Reynolds, Kerry;
- Zubiri, Leyre;
- Lawrence, Donald;
- Cohen, Justine V.;
- Sullivan, Ryan J.;
- Nachtigall, Lisa;
- Tritos, Nicholas
Publication type:
Article
Extended Follow-Up of Chronic Immune-Related Adverse Events Following Adjuvant Anti–PD-1 Therapy for High-Risk Resected Melanoma.
Published in:
JAMA Network Open, 2023, v. 6, n. 8, p. e2327145, doi. 10.1001/jamanetworkopen.2023.27145
By:
- Goodman, Rachel S.;
- Lawless, Aleigha;
- Woodford, Rachel;
- Fa'ak, Faisal;
- Tipirneni, Asha;
- Patrinely, J. Randall;
- Yeoh, Hui Ling;
- Rapisuwon, Suthee;
- Haydon, Andrew;
- Osman, Iman;
- Mehnert, Janice M.;
- Long, Georgina V.;
- Sullivan, Ryan J.;
- Carlino, Matteo S.;
- Menzies, Alexander M.;
- Johnson, Douglas B.
Publication type:
Article
Effects of immune‐related adverse events (irAEs) and their treatment on antitumor immune responses.
Published in:
Immunological Reviews, 2023, v. 318, n. 1, p. 167, doi. 10.1111/imr.13262
By:
- Blum, Steven M.;
- Rouhani, Sherin J.;
- Sullivan, Ryan J.
Publication type:
Article
The Great Debate at "Melanoma Bridge", Napoli, December 2nd, 2017.
Published in:
2018
By:
- Ascierto, Paolo A.;
- Caracò, Corrado;
- Gershenwald, Jeffrey E.;
- Hamid, Omid;
- Ross, Merrick;
- Sullivan, Ryan J.;
- Puzanov, Igor
Publication type:
journal article
Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy.
Published in:
Nature Communications, 2016, v. 7, n. 1, p. 10582, doi. 10.1038/ncomms10582
By:
- Johnson, Douglas B.;
- Estrada, Monica V.;
- Salgado, Roberto;
- Sanchez, Violeta;
- Doxie, Deon B.;
- Opalenik, Susan R.;
- Vilgelm, Anna E.;
- Feld, Emily;
- Johnson, Adam S.;
- Greenplate, Allison R.;
- Sanders, Melinda E.;
- Lovly, Christine M.;
- Frederick, Dennie T.;
- Kelley, Mark C.;
- Richmond, Ann;
- Irish, Jonathan M.;
- Shyr, Yu;
- Sullivan, Ryan J.;
- Puzanov, Igor;
- Sosman, Jeffrey A.
Publication type:
Article
High Throughput Strategies for the Discovery and Optimization of Catalytic Reactions.
Published in:
Angewandte Chemie International Edition, 2019, v. 58, n. 22, p. 7180, doi. 10.1002/anie.201812534
By:
- Isbrandt, Eric S.;
- Sullivan, Ryan J.;
- Newman, Stephen G.
Publication type:
Article
Severe Neurological Toxicity of Immune Checkpoint Inhibitors: Growing Spectrum.
Published in:
2020
By:
- Dubey, Divyanshu;
- David, William S.;
- Reynolds, Kerry L.;
- Chute, Donald F.;
- Clement, Nathan F.;
- Cohen, Justine V.;
- Lawrence, Donald P.;
- Mooradian, Meghan J.;
- Sullivan, Ryan J.;
- Guidon, Amanda C.
Publication type:
journal article
The "Great Debate" at Immunotherapy Bridge 2020, December 3rd, 2020.
Published in:
2021
By:
- Ascierto, Paolo A.;
- Brody, Joshua;
- Butterfield, Lisa H.;
- Finn, Olivera J.;
- Goldberg, John;
- Perrone, Francesco;
- Sullivan, Ryan J.;
- Fox, Bernard A.;
- Hwu, Patrick;
- Puzanov, Igor
Publication type:
journal article
Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy).
Published in:
2020
By:
- Ascierto, Paolo A.;
- Puzanov, Igor;
- Agarwala, Sanjiv S.;
- Blank, Christian;
- Carvajal, Richard D.;
- Demaria, Sandra;
- Dummer, Reinhard;
- Ernstoff, Marc;
- Ferrone, Soldano;
- Fox, Bernard A.;
- Gajewski, Thomas F.;
- Garbe, Claus;
- Hwu, Patrick;
- Lo, Roger S.;
- Long, Georgina V.;
- Luke, Jason J.;
- Osman, Iman;
- Postow, Michael A.;
- Sullivan, Ryan J.;
- Taube, Janis M.
Publication type:
journal article
Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies.
Published in:
2018
By:
- Mendzelevski, Boaz;
- Ferber, Georg;
- Janku, Filip;
- Li, Bob T.;
- Sullivan, Ryan J.;
- Welsch, Dean;
- Chi, Wei;
- Jackson, Jeanne;
- Weng, Onglee;
- Sager, Philip T.
Publication type:
journal article
Decreased Absolute Lymphocyte Count and Increased Neutrophil/Lymphocyte Ratio With Immune Checkpoint Inhibitor-Associated Myocarditis.
Published in:
2020
By:
- Drobni, Zsofia D.;
- Zafar, Amna;
- Zubiri, Leyre;
- Zlotoff, Daniel A.;
- Alvi, Raza M.;
- Lee, Charlotte;
- Hartmann, Sarah;
- Gilman, Hannah K.;
- Villani, Alexandra-Chloe;
- Nohria, Anju;
- Groarke, John D.;
- Sullivan, Ryan J.;
- Reynolds, Kerry L.;
- Zhang, Lili;
- Neilan, Tomas G.
Publication type:
journal article
Tebentafusp in the Treatment of Metastatic Uveal Melanoma: Patient Selection and Special Considerations.
Published in:
Drug Design, Development & Therapy, 2023, v. 17, p. 333, doi. 10.2147/DDDT.S368954
By:
- Montazeri, Kamaneh;
- Pattanayak, Vikram;
- Sullivan, Ryan J
Publication type:
Article
Clinical and genomic correlates of imatinib response in melanomas with KIT alterations.
Published in:
2022
By:
- Jung, Seungyeon;
- Armstrong, Emma;
- Wei, Alexander Z.;
- Ye, Fei;
- Lee, Aaron;
- Carlino, Matteo S.;
- Sullivan, Ryan J.;
- Carvajal, Richard D.;
- Shoushtari, Alexander N.;
- Johnson, Douglas B.
Publication type:
journal article
Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis.
Published in:
2021
By:
- Bhave, Prachi;
- Pallan, Lalit;
- Long, Georgina V.;
- Menzies, Alexander M.;
- Atkinson, Victoria;
- Cohen, Justine V.;
- Sullivan, Ryan J.;
- Chiarion-Sileni, Vanna;
- Nyakas, Marta;
- Kahler, Katharina;
- Hauschild, Axel;
- Plummer, Ruth;
- Trojaniello, Claudia;
- Ascierto, Paolo A.;
- Zimmer, Lisa;
- Schadendorf, Dirk;
- Allayous, Clara;
- Lebbe, Celeste;
- Maurichi, Andrea;
- Santinami, Mario
Publication type:
journal article
Secondary histiocytic sarcoma with BRAFV600E mutation responsive to MAPK‐targeted therapy presenting with recurrence with mTOR mutation responsive to mTOR‐targeted therapy.
Published in:
Pediatric Blood & Cancer, 2021, v. 68, n. 10, p. 1, doi. 10.1002/pbc.29166
By:
- Venkataraman, Vinayak;
- Massoth, Lucas R.;
- Sullivan, Ryan J.;
- Friedmann, Alison M.
Publication type:
Article
Secondary histiocytic sarcoma with BRAFV600E mutation responsive to MAPK-targeted therapy presenting with recurrence with mTOR mutation responsive to mTOR-targeted therapy.
Published in:
2021
By:
- Venkataraman, Vinayak;
- Massoth, Lucas R;
- Sullivan, Ryan J;
- Friedmann, Alison M
Publication type:
Letter
Secondary histiocytic sarcoma with BRAFV600E mutation after T-cell acute lymphoblastic leukemia in a very young child with dramatic response to dabrafenib and trametinib.
Published in:
2020
By:
- Venkataraman, Vinayak;
- Massoth, Lucas R.;
- Sullivan, Ryan J.;
- Friedmann, Alison M.
Publication type:
Case Study
HIV-associated multicentric Castleman's disease.
Published in:
American Journal of Hematology, 2008, v. 83, n. 6, p. 498, doi. 10.1002/ajh.21137
By:
- Stebbing, Justin;
- Pantanowitz, Liron;
- Dayyani, Farshid;
- Sullivan, Ryan J.;
- Bower, Mark;
- Dezube, Bruce J.
Publication type:
Article
Downregulation of KEAP1 in melanoma promotes resistance to immune checkpoint blockade.
Published in:
NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00362-3
By:
- Fox, Douglas B.;
- Ebright, Richard Y.;
- Hong, Xin;
- Russell, Hunter C.;
- Guo, Hongshan;
- LaSalle, Thomas J.;
- Wittner, Ben S.;
- Poux, Nicolas;
- Vuille, Joanna A.;
- Toner, Mehmet;
- Hacohen, Nir;
- Boland, Genevieve M.;
- Sen, Debattama R.;
- Sullivan, Ryan J.;
- Maheswaran, Shyamala;
- Haber, Daniel A.
Publication type:
Article
Tolerance and efficacy of BRAF plus MEK inhibition in patients with melanoma who previously have received programmed cell death protein 1-based therapy.
Published in:
2019
By:
- Saab, Karim R.;
- Mooradian, Meghan J.;
- Wang, Daniel Y.;
- Chon, Jeewon;
- Xia, Cathy Y.;
- Bialczak, Angelica;
- Abbate, Kelly T.;
- Menzies, Alexander M.;
- Johnson, Douglas B.;
- Sullivan, Ryan J.;
- Shoushtari, Alexander N.
Publication type:
journal article
Reply to emergency management of immune-related hypophysitis: Collaboration between specialists is essential to achieve optimal outcomes.
Published in:
2018
By:
- Faje, Alexander T.;
- Sullivan, Ryan J.
Publication type:
Letter
High-dose glucocorticoids for the treatment of ipilimumab-induced hypophysitis is associated with reduced survival in patients with melanoma.
Published in:
2018
By:
- Faje, Alexander T.;
- Lawrence, Donald;
- Flaherty, Keith;
- Freedman, Christine;
- Fadden, Riley;
- Rubin, Krista;
- Cohen, Justine;
- Sullivan, Ryan J.
Publication type:
journal article
Immune checkpoint inhibitors in challenging populations.
Published in:
2017
By:
- Johnson, Douglas B.;
- Sullivan, Ryan J.;
- Menzies, Alexander M.
Publication type:
journal article
Clinical outcomes in metastatic uveal melanoma treated with PD-1 and PD-L1 antibodies.
Published in:
2016
By:
- Algazi, Alain P.;
- Tsai, Katy K.;
- Shoushtari, Alexander N.;
- Munhoz, Rodrigo R.;
- Eroglu, Zeynep;
- Piulats, Josep M.;
- Ott, Patrick A.;
- Johnson, Douglas B.;
- Hwang, Jimmy;
- Daud, Adil I.;
- Sosman, Jeffrey A.;
- Carvajal, Richard D.;
- Chmielowski, Bartosz;
- Postow, Michael A.;
- Weber, Jeffrey S.;
- Sullivan, Ryan J.
Publication type:
journal article

Found: 71