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Chikungunya Virus Vaccines: A Review of IXCHIQ and PXVX0317 from Pre-Clinical Evaluation to Licensure.
Published in:
BioDrugs, 2024, v. 38, n. 6, p. 727, doi. 10.1007/s40259-024-00677-y
By:
- Weber, Whitney C.;
- Streblow, Daniel N.;
- Coffey, Lark L.
Publication type:
Article
Establishment of Monoclonal Antibody Standards for Quantitative Serological Diagnosis of SARS-CoV-2 in Low-Incidence Settings.
Published in:
Open Forum Infectious Diseases, 2021, v. 8, n. 3, p. 1, doi. 10.1093/ofid/ofab061
By:
- Thomas, Archana;
- Messer, William B;
- Hansel, Donna E;
- Streblow, Daniel N;
- Kazmierczak, Steven C;
- Lyski, Zoe L;
- Lu, Zhengchun;
- Slifka, Mark K
Publication type:
Article
Simian varicella virus gene expression during acute and latent infection of rhesus macaques.
Published in:
Journal of NeuroVirology, 2011, v. 17, n. 6, p. 600, doi. 10.1007/s13365-011-0057-y
By:
- Meyer, Christine;
- Kerns, Amelia;
- Barron, Alex;
- Kreklywich, Craig;
- Streblow, Daniel;
- Messaoudi, Ilhem
Publication type:
Article
Non-replicating adenovirus based Mayaro virus vaccine elicits protective immune responses and cross protects against other alphaviruses.
Published in:
PLoS Neglected Tropical Diseases, 2021, v. 15, n. 4, p. 1, doi. 10.1371/journal.pntd.0009308
By:
- Powers, John M.;
- Haese, Nicole N.;
- Denton, Michael;
- Ando, Takeshi;
- Kreklywich, Craig;
- Bonin, Kiley;
- Streblow, Cassilyn E.;
- Kreklywich, Nicholas;
- Smith, Patricia;
- Broeckel, Rebecca;
- DeFilippis, Victor;
- Morrison, Thomas E.;
- Heise, Mark T.;
- Streblow, Daniel N.
Publication type:
Article
Nonreciprocity in CHIKV and MAYV Vaccine-Elicited Protection.
Published in:
Vaccines, 2024, v. 12, n. 9, p. 970, doi. 10.3390/vaccines12090970
By:
- Weber, Whitney C.;
- Andoh, Takeshi F.;
- Kreklywich, Craig N.;
- Streblow, Zachary J.;
- Denton, Michael;
- Streblow, Magdalene M.;
- Powers, John M.;
- Sulgey, Gauthami;
- Medica, Samuel;
- Dmitriev, Igor;
- Curiel, David T.;
- Haese, Nicole N.;
- Streblow, Daniel N.
Publication type:
Article
The Approved Live-Attenuated Chikungunya Virus Vaccine (IXCHIQ ®) Elicits Cross-Neutralizing Antibody Breadth Extending to Multiple Arthritogenic Alphaviruses Similar to the Antibody Breadth Following Natural Infection.
Published in:
Vaccines, 2024, v. 12, n. 8, p. 893, doi. 10.3390/vaccines12080893
By:
- Weber, Whitney C.;
- Streblow, Zachary J.;
- Kreklywich, Craig N.;
- Denton, Michael;
- Sulgey, Gauthami;
- Streblow, Magdalene M.;
- Marcano, Dorca;
- Flores, Paola N.;
- Rodriguez-Santiago, Rachel M.;
- Alvarado, Luisa I.;
- Rivera-Amill, Vanessa;
- Messer, William B.;
- Hochreiter, Romana;
- Kosulin, Karin;
- Dubischar, Katrin;
- Buerger, Vera;
- Streblow, Daniel N.
Publication type:
Article
Differential regulation of cell motility and invasion by FAK.
Published in:
Journal of Cell Biology, 2003, v. 160, n. 5, p. 753, doi. 10.1083/jcb.200212114
By:
- Hsia, Datsun A.;
- Mitra, Satyajit K.;
- Hauck, Christof R.;
- Streblow, Daniel N.;
- Nelson, Jay A.;
- Ilic, Dusko;
- Shuang Huang;
- Erguang Li;
- Nemerow, Glen R.;
- Leng, Jay;
- Spencer, Kathryn S.R.;
- Chresh, David A.;
- Schlaepfer, David D.
Publication type:
Article
Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42440-x
By:
- Streblow, Daniel N.;
- Hirsch, Alec J.;
- Stanton, Jeffrey J.;
- Lewis, Anne D.;
- Colgin, Lois;
- Hessell, Ann J.;
- Kreklywich, Craig N.;
- Smith, Jessica L.;
- Sutton, William F.;
- Chauvin, David;
- Woo, Jennifer;
- Bimber, Benjamin N.;
- LeBlanc, Cierra N.;
- Acharya, Sonia N.;
- O'Roak, Brian J.;
- Sardar, Harjinder;
- Sajadi, Mohammad M.;
- Tehrani, Zahra R.;
- Walter, Mark R.;
- Martinez-Sobrido, Luis
Publication type:
Article
Vaccine-Induced Skewing of T Cell Responses Protects Against Chikungunya Virus Disease.
Published in:
Frontiers in Immunology, 2019, v. 10, p. 1, doi. 10.3389/fimmu.2019.02563
By:
- Broeckel, Rebecca M.;
- Haese, Nicole;
- Ando, Takeshi;
- Dmitriev, Igor;
- Kreklywich, Craig N.;
- Powers, John;
- Denton, Michael;
- Smith, Patricia;
- Morrison, Thomas E.;
- Heise, Mark;
- DeFilippis, Victor;
- Messaoudi, Ilhem;
- Curiel, David T.;
- Streblow, Daniel N.
Publication type:
Article
Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design.
Published in:
PLoS ONE, 2021, v. 16, n. 1, p. 1, doi. 10.1371/journal.pone.0245013
By:
- Zhang, Sixue;
- Garzan, Atefeh;
- Haese, Nicole;
- Bostwick, Robert;
- Martinez-Gzegozewska, Yohanka;
- Rasmussen, Lynn;
- Streblow, Daniel N.;
- Haise, Mark T.;
- Pathak, Ashish K.;
- Augelli-Szafran, Corinne E.;
- Wu, Mousheng
Publication type:
Article
In Utero Administration of Drugs Targeting Microglia Improves the Neurodevelopmental Outcome Following Cytomegalovirus Infection of the Rat Fetal Brain.
Published in:
Frontiers in Cellular Neuroscience, 2018, p. 1, doi. 10.3389/fncel.2018.00055
By:
- Cloarec, Robin;
- Bauer, Sylvian;
- Teissier, Natacha;
- Schaller, Fabienne;
- Luche, Hervé;
- Courtens, Sandra;
- Salmi, Manal;
- Pauly, Vanessa;
- Bois, Emilie;
- Pallesi-Pocachard, Emilie;
- Buhler, Emmanuelle;
- Michel, François J.;
- Gressens, Pierre;
- Malissen, Marie;
- Stamminger, Thomas;
- Streblow, Daniel N.;
- Bruneau, Nadine;
- Szepetowski, Pierre
Publication type:
Article
Human Cytomegalovirus Infection Suppresses CD34+ Progenitor Cell Engraftment in Humanized Mice.
Published in:
Microorganisms, 2020, v. 8, n. 4, p. 525, doi. 10.3390/microorganisms8040525
By:
- Crawford, Lindsey B.;
- Tempel, Rebecca;
- Streblow, Daniel N.;
- Yurochko, Andrew D.;
- Goodrum, Felicia D.;
- Nelson, Jay A.;
- Caposio, Patrizia
Publication type:
Article
Characterization of a live-attenuated HCMV-based vaccine platform.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-55508-w
By:
- Caposio, Patrizia;
- van den Worm, Sjoerd;
- Crawford, Lindsey;
- Perez, Wilma;
- Kreklywich, Craig;
- Gilbride, Roxanne M.;
- Hughes, Colette M.;
- Ventura, Abigail B.;
- Ratts, Robert;
- Marshall, Emily E.;
- Malouli, Daniel;
- Axthelm, Michael K.;
- Streblow, Daniel;
- Nelson, Jay A.;
- Picker, Louis J.;
- Hansen, Scott G.;
- Früh, Klaus
Publication type:
Article
HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinase.
Published in:
Herpesviridae, 2010, v. 1, n. 1, p. 1, doi. 10.1186/2042-4280-1-2
By:
- Vomaske, Jennifer;
- Varnum, Susan;
- Melnychuk, Ryan;
- Smith, Patricia;
- Pasa-Tolic, Ljiljana;
- Shutthanandan, Janani I;
- Streblow, Daniel N
Publication type:
Article
Rat Cytomegalovirus Virion-Associated Proteins R131 and R129 Are Necessary for Infection of Macrophages and Dendritic Cells.
Published in:
Pathogens, 2020, v. 9, n. 11, p. 963, doi. 10.3390/pathogens9110963
By:
- Jones, Iris K. A.;
- Haese, Nicole N.;
- Gatault, Philippe;
- Streblow, Zachary J.;
- Andoh, Takeshi F.;
- Denton, Michael;
- Streblow, Cassilyn E.;
- Bonin, Kiley;
- Kreklywich, Craig N.;
- Burg, Jennifer M.;
- Orloff, Susan L.;
- Streblow, Daniel N.
Publication type:
Article
Additives for vaccine storage to improve thermal stability of adenoviruses from hours to months.
Published in:
Nature Communications, 2016, v. 7, n. 11, p. 13520, doi. 10.1038/ncomms13520
By:
- Pelliccia, Maria;
- Andreozzi, Patrizia;
- Paulose, Jayson;
- D'Alicarnasso, Marco;
- Cagno, Valeria;
- Donalisio, Manuela;
- Civra, Andrea;
- Broeckel, Rebecca M.;
- Haese, Nicole;
- Jacob Silva, Paulo;
- Carney, Randy P.;
- Marjomäki, Varpu;
- Streblow, Daniel N.;
- Lembo, David;
- Stellacci, Francesco;
- Vitelli, Vincenzo;
- Krol, Silke
Publication type:
Article
Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity.
Published in:
Science Translational Medicine, 2019, v. 11, n. 501, p. 1, doi. 10.1126/scitranslmed.aaw2603
By:
- Marshall, Emily E.;
- Malouli, Daniel;
- Hansen, Scott G.;
- Gilbride, Roxanne M.;
- Hughes, Colette M.;
- Ventura, Abigail B.;
- Ainslie, Emily;
- Selseth, Andrea N.;
- Ford, Julia C.;
- Burke, David;
- Kreklywich, Craig N.;
- Womack, Jennie;
- Legasse, Alfred W.;
- Axthelm, Michael K.;
- Kahl, Christoph;
- Streblow, Daniel;
- Edlefsen, Paul T.;
- Picker, Louis J.;
- Früh, Klaus
Publication type:
Article
Nonhuman Primate Models of Zika Virus Infection and Disease during Pregnancy.
Published in:
Viruses (1999-4915), 2021, v. 13, n. 10, p. 2088, doi. 10.3390/v13102088
By:
- Haese, Nicole N.;
- Roberts, Victoria H. J.;
- Chen, Athena;
- Streblow, Daniel N.;
- Morgan, Terry K.;
- Hirsch, Alec J.
Publication type:
Article
Characterization of a Novel Human-Specific STING Agonist that Elicits Antiviral Activity Against Emerging Alphaviruses.
Published in:
PLoS Pathogens, 2015, v. 11, n. 12, p. 1, doi. 10.1371/journal.ppat.1005324
By:
- Sali, Tina M.;
- Pryke, Kara M.;
- Abraham, Jinu;
- Liu, Andrew;
- Archer, Iris;
- Broeckel, Rebecca;
- Staverosky, Julia A.;
- Smith, Jessica L.;
- Al-Shammari, Ahmed;
- Amsler, Lisi;
- Sheridan, Kayla;
- Nilsen, Aaron;
- Streblow, Daniel N.;
- DeFilippis, Victor R.
Publication type:
Article
Human Cytomegalovirus miR-UL112-3p Targets TLR2 and Modulates the TLR2/IRAK1/NFκB Signaling Pathway.
Published in:
PLoS Pathogens, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.ppat.1004881
By:
- Landais, Igor;
- Pelton, Chantel;
- Streblow, Daniel;
- DeFilippis, Victor;
- McWeeney, Shannon;
- Nelson, Jay A.
Publication type:
Article
A Novel Human Cytomegalovirus Locus Modulates Cell Type-Specific Outcomes of Infection.
Published in:
PLoS Pathogens, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.ppat.1002444
By:
- Umashankar, Mahadevaiah;
- Petrucelli, Alex;
- Cicchini, Louis;
- Caposio, Patrizia;
- Kreklywich, Craig N.;
- Rak, Michael;
- Bughio, Farah;
- Goldman, Devorah C.;
- Hamlin, Kimberly L.;
- Nelson, Jay A.;
- Fleming, William H.;
- Streblow, Daniel N.;
- Goodrum, Felicia
Publication type:
Article
Differential Ligand Binding to a Human Cytomegalovirus Chemokine Receptor Determines Cell Type-Specific Motility.
Published in:
PLoS Pathogens, 2009, v. 5, n. 2, p. 1, doi. 10.1371/journal.ppat.1000304
By:
- Vomaske, Jennifer;
- Melnychuk, Ryan M.;
- Smith, Patricia P.;
- Powell, Joshua;
- Hall, Laurel;
- DeFilippis, Victor;
- Früh, Klaus;
- Smit, Martine;
- Schlaepfer, David D.;
- Nelson, Jay A.;
- Streblow, Daniel N.
Publication type:
Article
Cytomegalovirus Infection of the Rat Developing Brain In Utero Prominently Targets Immune Cells and Promotes Early Microglial Activation.
Published in:
PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0160176
By:
- Cloarec, Robin;
- Bauer, Sylvian;
- Luche, Hervé;
- Buhler, Emmanuelle;
- Pallesi-Pocachard, Emilie;
- Salmi, Manal;
- Courtens, Sandra;
- Massacrier, Annick;
- Grenot, Pierre;
- Teissier, Natacha;
- Watrin, Françoise;
- Schaller, Fabienne;
- Adle-Biassette, Homa;
- Gressens, Pierre;
- Malissen, Marie;
- Stamminger, Thomas;
- Streblow, Daniel N.;
- Bruneau, Nadine;
- Szepetowski, Pierre
Publication type:
Article
Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques.
Published in:
PLoS Pathogens, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.ppat.1006014
By:
- Burwitz, Benjamin J.;
- Malouli, Daniel;
- Bimber, Benjamin N.;
- Reed, Jason S.;
- Ventura, Abigail B.;
- Hancock, Meaghan H.;
- Uebelhoer, Luke S.;
- Bhusari, Amruta;
- Hammond, Katherine B.;
- Espinosa Trethewy, Renee G.;
- Klug, Alex;
- Legasse, Alfred W.;
- Axthelm, Michael K.;
- Nelson, Jay A.;
- Park, Byung S.;
- Streblow, Daniel N.;
- Hansen, Scott G.;
- Picker, Louis J.;
- Früh, Klaus;
- Sacha, Jonah B.
Publication type:
Article
Dysregulated TGF-β Production Underlies the Age-Related Vulnerability to Chikungunya Virus.
Published in:
PLoS Pathogens, 2016, v. 12, n. 10, p. 1, doi. 10.1371/journal.ppat.1005891
By:
- Uhrlaub, Jennifer L.;
- Pulko, Vesna;
- DeFilippis, Victor R.;
- Broeckel, Rebecca;
- Streblow, Daniel N.;
- Coleman, Gary D.;
- Park, Byung S.;
- Lindo, John F.;
- Vickers, Ivan;
- Anzinger, Joshua J.;
- Nikolich-Žugich, Janko
Publication type:
Article
Human Cytomegalovirus Host Interactions: EGFR and Host Cell Signaling Is a Point of Convergence Between Viral Infection and Functional Changes in Infected Cells.
Published in:
Frontiers in Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fmicb.2021.660901
By:
- Lee, Byeong-Jae;
- Min, Chan-Ki;
- Hancock, Meaghan;
- Streblow, Daniel N.;
- Caposio, Patrizia;
- Goodrum, Felicia D.;
- Yurochko, Andrew D.
Publication type:
Article
The Differentiation of Human Cytomegalovirus Infected-Monocytes Is Required for Viral Replication.
Published in:
Frontiers in Cellular & Infection Microbiology, 2020, v. 2020, p. N.PAG, doi. 10.3389/fcimb.2020.00368
By:
- Min, Chan-Ki;
- Shakya, Akhalesh K.;
- Lee, Byeong-Jae;
- Streblow, Daniel N.;
- Caposio, Patrizia;
- Yurochko, Andrew D.
Publication type:
Article
Chikungunya Virus Infection Results in Higher and Persistent Viral Replication in Aged Rhesus Macaques Due to Defects in Anti-Viral Immunity.
Published in:
PLoS Neglected Tropical Diseases, 2013, v. 7, n. 7, p. 1, doi. 10.1371/journal.pntd.0002343
By:
- Messaoudi, Ilhem;
- Vomaske, Jennifer;
- Totonchy, Thomas;
- Kreklywich, Craig N.;
- Haberthur, Kristen;
- Springgay, Laura;
- Brien, James D.;
- Diamond, Michael S.;
- DeFilippis, Victor R.;
- Streblow, Daniel N.
Publication type:
Article
Chikungunya Virus Infection Results in Higher and Persistent Viral Replication in Aged Rhesus Macaques Due to Defects in Anti-Viral Immunity.
Published in:
PLoS Neglected Tropical Diseases, 2013, v. 7, n. 7, p. 1, doi. 10.1371/journal.pntd.0002343
By:
- Messaoudi, Ilhem;
- Vomaske, Jennifer;
- Totonchy, Thomas;
- Kreklywich, Craig N.;
- Haberthur, Kristen;
- Springgay, Laura;
- Brien, James D.;
- Diamond, Michael S.;
- DeFilippis, Victor R.;
- Streblow, Daniel N.
Publication type:
Article
Macrophage depletion of CMV latently infected donor hearts ameliorates recipient accelerated chronic rejection.
Published in:
Transplant Infectious Disease, 2021, v. 23, n. 2, p. 1, doi. 10.1111/tid.13514
By:
- Haese, Nicole N.;
- Burg, Jennifer M.;
- Andoh, Takeshi F.;
- Jones, Iris K. A.;
- Kreklywich, Craig N.;
- Smith, Patricia P.;
- Orloff, Susan L.;
- Streblow, Daniel N.
Publication type:
Article
Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory B-cells against other arthritogenic alphaviruses predominantly through the B domain of the E2 glycoprotein.
Published in:
PLoS Neglected Tropical Diseases, 2023, v. 16, n. 3, p. 1, doi. 10.1371/journal.pntd.0011154
By:
- Powers, John M.;
- Lyski, Zoe L.;
- Weber, Whitney C.;
- Denton, Michael;
- Streblow, Magdalene M.;
- Mayo, Adam T.;
- Haese, Nicole N.;
- Nix, Chad D.;
- Rodríguez-Santiago, Rachel;
- Alvarado, Luisa I.;
- Rivera-Amill, Vanessa;
- Messer, William B.;
- Streblow, Daniel N.
Publication type:
Article
Zika Virus Causes Acute and Chronic Prostatitis in Mice and Macaques.
Published in:
Journal of Infectious Diseases, 2020, v. 221, n. 9, p. 1506, doi. 10.1093/infdis/jiz533
By:
- Halabi, Jacques;
- Jagger, Brett W.;
- Salazar, Vanessa;
- Winkler, Emma S.;
- Whitex, James P.;
- Humphrey, Peter A.;
- Hirsch, Alec J.;
- Streblow, Daniel N.;
- Diamond, Michael S.;
- Moley, Kelle
Publication type:
Article
Animal Models of Chikungunya Virus Infection and Disease.
Published in:
2016
By:
- Haese, Nicole N.;
- Broeckel, Rebecca M.;
- Hawman, David W.;
- Heise, Mark T.;
- Morrison, Thomas E.;
- Streblow, Daniel N.
Publication type:
journal article
Human cytomegalovirus induces upregulation of arginase II: possible implications for vasculopathies.
Published in:
Basic Research in Cardiology, 2014, v. 109, n. 2, p. 1, doi. 10.1007/s00395-014-0401-5
By:
- Yaiw, Koon-Chu;
- Mohammad, Abdul-Aleem;
- Taher, Chato;
- Wilhelmi, Vanessa;
- Davoudi, Belghis;
- Strååt, Klas;
- Assinger, Alice;
- Ovchinnikova, Olga;
- Shlyakhto, Eugene;
- Rahbar, Afsar;
- Koutonguk, Oksana;
- Religa, Piotr;
- Butler, Lynn;
- Khan, Zahidul;
- Streblow, Daniel;
- Pernow, John;
- Söderberg-Nauclér, Cecilia
Publication type:
Article
Proximity-dependent mapping of the HCMV US28 interactome identifies RhoGEF signaling as a requirement for efficient viral reactivation.
Published in:
PLoS Pathogens, 2023, v. 19, n. 10, p. 1, doi. 10.1371/journal.ppat.1011682
By:
- Medica, Samuel;
- Crawford, Lindsey B.;
- Denton, Michael;
- Min, Chan-Ki;
- Jones, Taylor A.;
- Alexander, Timothy;
- Parkins, Christopher J.;
- Diggins, Nicole L.;
- Streblow, Gabriel J.;
- Mayo, Adam T.;
- Kreklywich, Craig N.;
- Smith, Patricia;
- Jeng, Sophia;
- McWeeney, Shannon;
- Hancock, Meaghan H.;
- Yurochko, Andrew;
- Cohen, Michael S.;
- Caposio, Patrizia;
- Streblow, Daniel N.
Publication type:
Article
Development of a next-generation chikungunya virus vaccine based on the HydroVax platform.
Published in:
PLoS Pathogens, 2022, v. 18, n. 7, p. 1, doi. 10.1371/journal.ppat.1010695
By:
- Slifka, Dawn K.;
- Raué, Hans-Peter;
- Weber, Whitney C.;
- Andoh, Takeshi F.;
- Kreklywich, Craig N.;
- DeFilippis, Victor R.;
- Streblow, Daniel N.;
- Slifka, Mark K.;
- Amanna, Ian J.
Publication type:
Article

Found: 36