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The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFβ signalling in cardiac fibroblasts.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99032-2
By:
- Rypdal, Karoline B.;
- Erusappan, Pugazendhi M.;
- Melleby, A. Olav;
- Seifert, Deborah E.;
- Palmero, Sheryl;
- Strand, Mari E.;
- Tønnessen, Theis;
- Dahl, Christen P.;
- Almaas, Vibeke;
- Hubmacher, Dirk;
- Apte, Suneel S.;
- Christensen, Geir;
- Lunde, Ida G.
Publication type:
Article
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice.
Published in:
Cardiovascular Research, 2015, v. 106, n. 1, p. 32, doi. 10.1093/cvr/cvv041
By:
- Skrbic, Biljana;
- Engebretsen, Kristin V. T.;
- Strand, Mari E.;
- Lunde, Ida G.;
- Herum, Kate M.;
- Marstein, Henriette S.;
- Sjaastad, Ivar;
- Lunde, Per K.;
- Carlson, Cathrine R.;
- Christensen, Geir;
- Bjørnstad, Johannes L.;
- Tønnessen, Theis
Publication type:
Article
The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-45651-9
By:
- Mohammadzadeh, Naiyereh;
- Lunde, Ida G.;
- Andenæs, Kine;
- Strand, Mari E.;
- Aronsen, Jan Magnus;
- Skrbic, Biljana;
- Marstein, Henriette S.;
- Bandlien, Caroline;
- Nygård, Ståle;
- Gorham, Joshua;
- Sjaastad, Ivar;
- Chakravarti, Shukti;
- Christensen, Geir;
- Engebretsen, Kristin V. T.;
- Tønnessen, Theis
Publication type:
Article
Lumican is increased in experimental and clinical heart failure, and its production by cardiac fibroblasts is induced by mechanical and proinflammatory stimuli.
Published in:
FEBS Journal, 2013, v. 280, n. 10, p. 2382, doi. 10.1111/febs.12235
By:
- Engebretsen, Kristin V. T.;
- Lunde, Ida G.;
- Strand, Mari E.;
- Waehre, Anne;
- Sjaastad, Ivar;
- Marstein, Henriette S.;
- Skrbic, Biljana;
- Dahl, Christen P.;
- Askevold, Erik T.;
- Christensen, Geir;
- Bjørnstad, Johannes L.;
- Tønnessen, Theis
Publication type:
Article
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart.
Published in:
FEBS Journal, 2013, v. 280, n. 10, p. 2228, doi. 10.1111/febs.12161
By:
- Strand, Mari E.;
- Herum, Kate M.;
- Rana, Zaheer A.;
- Skrbic, Biljana;
- Askevold, Erik T.;
- Dahl, Christen P.;
- Vistnes, Maria;
- Hasic, Almira;
- Kvaløy, Heidi;
- Sjaastad, Ivar;
- Carlson, Cathrine R.;
- Tønnessen, Theis;
- Gullestad, Lars;
- Christensen, Geir;
- Lunde, Ida G.
Publication type:
Article
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin.
Published in:
2020
By:
- Herum, Kate M;
- Romaine, Andreas;
- Wang, Ariel;
- Melleby, Arne Olav;
- Strand, Mari E;
- Pacheco, Julian;
- Braathen, Bjørn;
- Dunér, Pontus;
- Tønnessen, Theis;
- Lunde, Ida G;
- Sjaastad, Ivar;
- Brakebusch, Cord;
- McCulloch, Andrew D;
- Gomez, Maria F;
- Carlson, Cathrine R;
- Christensen, Geir
Publication type:
journal article
The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0165079
By:
- Melleby, Arne O.;
- Strand, Mari E.;
- Romaine, Andreas;
- Herum, Kate M.;
- Skrbic, Biljana;
- Dahl, Christen P.;
- Sjaastad, Ivar;
- Fiane, Arnt E.;
- Filmus, Jorge;
- Christensen, Geir;
- Lunde, Ida G.
Publication type:
Article
Inflammation and Syndecan-4 Shedding from Cardiac Cells in Ischemic and Non-Ischemic Heart Disease.
Published in:
Biomedicines, 2023, v. 11, n. 4, p. 1066, doi. 10.3390/biomedicines11041066
By:
- Strand, Mari E.;
- Vanhaverbeke, Maarten;
- Henkens, Michiel T. H. M.;
- Sikking, Maurits A.;
- Rypdal, Karoline B.;
- Braathen, Bjørn;
- Almaas, Vibeke M.;
- Tønnessen, Theis;
- Christensen, Geir;
- Heymans, Stephane;
- Lunde, Ida G.
Publication type:
Article
Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy.
Published in:
Molecular Biology Reports, 2022, v. 49, n. 12, p. 11795, doi. 10.1007/s11033-022-07985-y
By:
- Lunde, Ida G.;
- Aronsen, J. Magnus;
- Melleby, A. Olav;
- Strand, Mari E.;
- Skogestad, Jonas;
- Bendiksen, Bård A.;
- Ahmed, M. Shakil;
- Sjaastad, Ivar;
- Attramadal, Håvard;
- Carlson, Cathrine R.;
- Christensen, Geir
Publication type:
Article
The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling.
Published in:
PLoS ONE, 2018, v. 13, n. 7, p. 1, doi. 10.1371/journal.pone.0201422
By:
- Andenæs, Kine;
- Lunde, Ida G.;
- Mohammadzadeh, Naiyereh;
- Dahl, Christen P.;
- Aronsen, Jan Magnus;
- Strand, Mari E.;
- Palmero, Sheryl;
- Sjaastad, Ivar;
- Christensen, Geir;
- Engebretsen, Kristin V. T.;
- Tønnessen, Theis
Publication type:
Article

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