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Nanobody‐Enabled Reverse Pharmacology on G‐Protein‐Coupled Receptors.
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- Angewandte Chemie, 2018, v. 130, n. 19, p. 5390, doi. 10.1002/ange.201712581
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- Article
BRET evidence that β2 adrenergic receptors do not oligomerize in cells.
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- Scientific Reports, 2015, p. 10166, doi. 10.1038/srep10166
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- Article
Recombinant Human Prion Protein Inhibits Prion Propagation in vitro.
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- Scientific Reports, 2013, p. 1, doi. 10.1038/srep02911
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Structure and function of the EA1 surface layer of Bacillus anthracis.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42826-x
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Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40911-9
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Sortase A-mediated site-specific labeling of camelid single-domain antibody-fragments: a versatile strategy for multiple molecular imaging modalities.
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- Contrast Media & Molecular Imaging, 2016, v. 11, n. 5, p. 328, doi. 10.1002/cmmi.1696
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A llama-derived gelsolin single-domain antibody blocks gelsolin–G-actin interaction.
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- Cellular & Molecular Life Sciences, 2010, v. 67, n. 9, p. 1519, doi. 10.1007/s00018-010-0266-1
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Combining in-situ proteolysis and microseed matrix screening to promote crystallization of PrPc-nanobody complexes.
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- PEDS: Protein Engineering, Design & Selection, 2011, v. 24, n. 9, p. 737, doi. 10.1093/protein/gzr017
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Crystal structure of human serum albumin in complex with megabody reveals unique human and murine cross‐reactive binding site.
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- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 2, p. 1, doi. 10.1002/pro.4887
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Stabilization of Meta‐I Rhodopsin Conformation by a Nanobody.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2572
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Structure of Nanobody Nb23.
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- Molecules, 2021, v. 26, n. 12, p. 3567, doi. 10.3390/molecules26123567
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An improved yeast surface display platform for the screening of nanobody immune libraries.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37212-3
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Development by genetic immunization of Monovalent antibodies against human Vasoactive intestinal Peptide receptor 1 (VPac1), new innovative, and Versatile Tools to study VPac1 receptor Function.
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- Frontiers in Endocrinology, 2018, p. 1, doi. 10.3389/fendo.2018.00153
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Structural and Functional Studies on the Interaction of GspC and GspD in the Type II Secretion System.
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- PLoS Pathogens, 2011, v. 7, n. 9, p. 1, doi. 10.1371/journal.ppat.1002228
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SbsB structure and lattice reconstruction unveil Ca<sup>2+</sup> triggered S-layer assembly.
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- Nature, 2012, v. 487, n. 7405, p. 119, doi. 10.1038/nature11155
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- Article
Crystal structure of the ?<sub>2</sub> adrenergic receptor-Gs protein complex.
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- Nature, 2011, v. 477, n. 7366, p. 549, doi. 10.1038/nature10361
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Structure of a nanobody-stabilized active state of the β<sub>2</sub> adrenoceptor.
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- Nature, 2011, v. 469, n. 7329, p. 175, doi. 10.1038/nature09648
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A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations.
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- eLife, 2021, p. 1, doi. 10.7554/eLife.64922
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In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters.
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- eLife, 2020, p. 1, doi. 10.7554/eLife.64389
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- Article
Nanobody‐Enabled Reverse Pharmacology on G‐Protein‐Coupled Receptors.
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- Angewandte Chemie International Edition, 2018, v. 57, n. 19, p. 5292, doi. 10.1002/anie.201712581
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- Article
Structural and biochemical characterization of the nucleoside hydrolase from C . elegans reveals the role of two active site cysteine residues in catalysis.
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- Protein Science: A Publication of the Protein Society, 2017, v. 26, n. 5, p. 985, doi. 10.1002/pro.3141
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Structure of an early native-like intermediate of β2-microglobulin amyloidogenesis.
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- Protein Science: A Publication of the Protein Society, 2013, v. 22, n. 10, p. 1349, doi. 10.1002/pro.2321
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Dissection of the structural and functional role of a conserved hydration site in RNase T1.
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- Protein Science: A Publication of the Protein Society, 1999, v. 8, n. 4, p. 722
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Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family.
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- Nature Structural & Molecular Biology, 2015, v. 22, n. 10, p. 803, doi. 10.1038/nsmb.3091
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Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.
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- Nature Structural & Molecular Biology, 2014, v. 21, n. 11, p. 990, doi. 10.1038/nsmb.2904
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Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies.
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- Biochemical Journal, 2020, v. 477, n. 7, p. 1203, doi. 10.1042/BCJ20190843
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Structure and nucleotide-induced conformational dynamics of the Chlorobium tepidum Roco protein.
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- Biochemical Journal, 2019, v. 476, n. 1, p. 51, doi. 10.1042/BCJ20180803
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Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT<sub>3</sub> receptor via a common vestibule site.
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- eLife, 2020, p. 1, doi. 10.7554/eLife.51511
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- Article
L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09837-z
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Crystal structure of human Mediator subunit MED23.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05967-y
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- Article
Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04432-0
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- Article
A general protocol for the generation of Nanobodies for structural biology.
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- Nature Protocols, 2014, v. 9, n. 3, p. 674, doi. 10.1038/nprot.2014.039
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Nanobody Loop Mimetics Enhance Son of Sevenless 1‐Catalyzed Nucleotide Exchange on RAS.
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- Angewandte Chemie International Edition, 2023, v. 62, n. 24, p. 1, doi. 10.1002/anie.202219095
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Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion.
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- PLoS Pathogens, 2019, v. 15, n. 12, p. 1, doi. 10.1371/journal.ppat.1008139
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Nanobody Mediated Crystallization of an Archeal Mechanosensitive Channel.
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- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077984
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Mapping the Binding Interface between an HIV-1 Inhibiting Intrabody and the Viral Protein Rev.
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- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060259
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CANON SOCIAAL WERK: VIRTUELE GESCHIEDENIS VAN EEN BEROEP.
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- Brood & Rozen: Tijdschrift voor de Geschiedenis van Sociale Bewegingen, 2013, v. 18, n. 2, p. 4, doi. 10.21825/br.v18i2.3521
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Propagation of conformational changes during μ-opioid receptor activation.
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- Nature, 2015, v. 524, n. 7565, p. 375, doi. 10.1038/nature14680
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Structural insights into µ-opioid receptor activation.
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- Nature, 2015, v. 524, n. 7565, p. 315, doi. 10.1038/nature14886
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Activation and allosteric modulation of a muscarinic acetylcholine receptor.
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- Nature, 2013, v. 504, n. 7478, p. 101, doi. 10.1038/nature12735
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Conformational biosensors reveal GPCR signalling from endosomes.
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- Nature, 2013, v. 495, n. 7442, p. 534, doi. 10.1038/nature12000
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Nanobody‐aided crystallization of the transcription regulator PaaR2 from Escherichia coli O157:H7.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2021, v. 77, n. 10, p. 374, doi. 10.1107/S2053230X21009006
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Characterization and structure determination of a llama‐derived nanobody targeting the J‐base binding protein 1.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2018, v. 74, n. 11, p. 690, doi. 10.1107/S2053230X18010282
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Production, crystallization and preliminary X-ray diffraction of the Gαs α-helical domain in complex with a nanobody.
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- Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 11, p. 1504, doi. 10.1107/S2053230X14020962
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- Article
Structural basis of inhibition of lipid-linked oligosaccharide flippase PglK by a conformational nanobody.
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- Scientific Reports, 2017, p. 46641, doi. 10.1038/srep46641
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Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27950-w
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Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27950-w
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- Article
Diversity in kinetics correlated with structure in nano body-stabilized LacY.
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- PLoS ONE, 2020, v. 15, n. 5, p. 1, doi. 10.1371/journal.pone.0232846
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- Article
Synthesis of Bicyclic N-Arylmethyl-Substituted Iminoribitol Derivatives as Selective Nucleoside Hydrolase Inhibitors.
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- ChemMedChem, 2009, v. 4, n. 2, p. 249, doi. 10.1002/cmdc.200800231
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A novel expression system for production of soluble prion proteins in E. coli.
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- Microbial Cell Factories, 2012, v. 11, n. 1, p. 1, doi. 10.1186/1475-2859-11-6
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- Article