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Exposure–Response Analysis of the Sodium–Glucose Cotransporter-2 Inhibitors Dapagliflozin and Empagliflozin on Kidney Hemodynamics in Patients with Type 2 Diabetes.
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- Journal of Personalized Medicine, 2023, v. 13, n. 5, p. 747, doi. 10.3390/jpm13050747
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- Article
Effect of Food on the Pharmacokinetics of 2 Formulations of DRL‐17822, a Novel Selective Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Males.
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- Clinical Pharmacology in Drug Development, 2019, v. 8, n. 8, p. 1042, doi. 10.1002/cpdd.707
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- Article
Current Use and Complementary Value of Combining in Vivo Imaging Modalities to Understand the Renoprotective Effects of Sodium-Glucose Cotransporter-2 Inhibitors at a Tissue Level.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.837993
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- Article
Treatment Outcomes of Childhood Tuberculous Meningitis in a Real-World Retrospective Cohort, Bandung, Indonesia.
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- 2022
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- Publication type:
- journal article
Clinical and Radiological Outcomes of Subtalar Kalix II Arthroereisis for a Symptomatic Pediatric Flexible Flatfoot.
- Published in:
- 2021
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- Publication type:
- journal article
Fosfomycin: Pharmacological, Clinical and Future Perspectives.
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- Antibiotics (2079-6382), 2017, v. 6, n. 4, p. 24, doi. 10.3390/antibiotics6040024
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- Publication type:
- Article
A Review of the Dose Justification of Phase 3 Trials to Regulatory Authorities for Drugs Intended for the Treatment of Type 2 Diabetes in Europe.
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- Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.626766
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- Publication type:
- Article
Inter‐individual variability in atrasentan exposure partly explains variability in kidney protection and fluid retention responses: A post hoc analysis of the SONAR trial.
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- Diabetes, Obesity & Metabolism, 2021, v. 23, n. 2, p. 561, doi. 10.1111/dom.14252
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- Article
Exposure–response relationships for the sodium‐glucose co‐transporter‐2 inhibitor dapagliflozin with regard to renal risk markers.
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- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 6, p. 916, doi. 10.1111/dom.13976
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- Article
Exposure and response analysis of aleglitazar on cardiovascular risk markers and safety outcomes: An analysis of the AleCardio trial.
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- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 1, p. 30, doi. 10.1111/dom.13862
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- Article
Association between individual cholesterol and proteinuria response and exposure to atorvastatin or rosuvastatin.
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- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 12, p. 2635, doi. 10.1111/dom.13849
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- Article
Association between individual cholesterol and proteinuria response and exposure to atorvastatin or rosuvastatin.
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- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 12, p. 2635, doi. 10.1111/dom.13849
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- Publication type:
- Article
Determining the optimal dose of atrasentan by evaluating the exposure‐response relationships of albuminuria and bodyweight.
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- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 8, p. 2019, doi. 10.1111/dom.13312
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- Publication type:
- Article
How are growth hormone and insulin-like growth factor-1 reported as markers for drug effectiveness in clinical acromegaly research? A comprehensive methodologic review.
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- Pituitary, 2018, v. 21, n. 3, p. 310, doi. 10.1007/s11102-018-0884-4
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- Publication type:
- Article
Safety, pharmacokinetics and pharmacodynamics of HTL0009936, a selective muscarinic M<sub>1</sub>‐acetylcholine receptor agonist: A randomized cross‐over trial.
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- British Journal of Clinical Pharmacology, 2021, v. 87, n. 11, p. 4439, doi. 10.1111/bcp.14872
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- Article
Exposure–response relationships of dapagliflozin on cardiorenal risk markers and adverse events: A pooled analysis of 13 phase II/III trials.
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- British Journal of Clinical Pharmacology, 2020, v. 86, n. 11, p. 2192, doi. 10.1111/bcp.14318
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- Publication type:
- Article
The effect of food and formulation on the population pharmacokinetics of cholesteryl ester transferase protein inhibitor DRL‐17822 in healthy male volunteers.
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- British Journal of Clinical Pharmacology, 2020, v. 86, n. 10, p. 2095, doi. 10.1111/bcp.14297
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- Publication type:
- Article
Model informed quantification of the feed‐forward stimulation of growth hormone by growth hormone‐releasing hormone.
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- British Journal of Clinical Pharmacology, 2020, v. 86, n. 8, p. 1575, doi. 10.1111/bcp.14265
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- Publication type:
- Article
An anti-nicotinic cognitive challenge model using mecamylamine in comparison with the anti-muscarinic cognitive challenge using scopolamine.
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- British Journal of Clinical Pharmacology, 2017, v. 83, n. 8, p. 1676, doi. 10.1111/bcp.13268
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- Article
The use of a battery of pain models to detect analgesic properties of compounds: a two-part four-way crossover study.
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- British Journal of Clinical Pharmacology, 2017, v. 83, n. 5, p. 976, doi. 10.1111/bcp.13183
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- Publication type:
- Article
Model-based exposure-response analysis to quantify age related differences in the response to scopolamine in healthy subjects.
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- British Journal of Clinical Pharmacology, 2016, v. 82, n. 4, p. 1011, doi. 10.1111/bcp.13031
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- Publication type:
- Article
Pharmacokinetic/pharmaco-dynamic modelling and simulation of the effects of different cannabinoid receptor type 1 antagonists on Δ<sup>9</sup>-tetrahydrocannabinol challenge tests.
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- British Journal of Clinical Pharmacology, 2016, v. 81, n. 4, p. 713, doi. 10.1111/bcp.12852
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- Article
Identifying 24 h variation in the pharmacokinetics of levofloxacin: a population pharmacokinetic approach.
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- British Journal of Clinical Pharmacology, 2016, v. 81, n. 2, p. 256, doi. 10.1111/bcp.12783
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- Article
Bayesian model of Hamilton Depression Rating Score ( HDRS) with memantine augmentation in bipolar depression.
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- British Journal of Clinical Pharmacology, 2013, v. 75, n. 3, p. 791, doi. 10.1111/j.1365-2125.2012.04398.x
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- Publication type:
- Article
Feasibility Study to Assess Canagliflozin Distribution and Sodium‐Glucose Co‐Transporter 2 Occupancy Using [<sup>18</sup>F]Canagliflozin in Patients with Type 2 Diabetes.
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- Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 6, p. 1295, doi. 10.1002/cpt.2886
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- Article
Studying Telmisartan Plasma Exposure, Kidney Distribution, Receptor Occupancy, and Response in Patients With Type 2 Diabetes Using [<sup>11</sup>C]Telmisartan.
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- Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 6, p. 1264, doi. 10.1002/cpt.2744
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- Publication type:
- Article
Individual Atrasentan Exposure is Associated With Long‐term Kidney and Heart Failure Outcomes in Patients With Type 2 Diabetes and Chronic Kidney Disease.
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- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1631, doi. 10.1002/cpt.2143
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- Article
Population Pharmacokinetic/Pharmacodynamic Analysis of Nociceptive Pain Models Following an Oral Pregabalin Dose Administration to Healthy Subjects.
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- CPT: Pharmacometrics & Systems Pharmacology, 2018, v. 7, n. 9, p. 573, doi. 10.1002/psp4.12318
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- Article
Simplified Iohexol-Based Method for Measurement of Glomerular Filtration Rate in Goats and Pigs.
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- Biology (2079-7737), 2021, v. 10, n. 6, p. 461, doi. 10.3390/biology10060461
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- Article
Pharmacokinetics of rituximab in a pediatric patient with therapy-resistant nephrotic syndrome.
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- Pediatric Nephrology, 2015, v. 30, n. 8, p. 1367, doi. 10.1007/s00467-015-3120-8
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- Article
Pharmacokinetic Modeling and Dose Selection in a Randomized, Double-Blind, Placebo-Controlled Trial of a Human Recombinant Alkaline Phosphatase in Healthy Volunteers.
- Published in:
- 2016
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- Publication type:
- journal article
The power of modelling pulsatile profiles.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2021, v. 48, n. 3, p. 439, doi. 10.1007/s10928-021-09743-2
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- Article
Quantification of the endogenous growth hormone and prolactin lowering effects of a somatostatin-dopamine chimera using population PK/PD modeling.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 3, p. 229, doi. 10.1007/s10928-020-09683-3
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- Publication type:
- Article
A two-step deconvolution-analysis-informed population pharmacodynamic modeling approach for drugs targeting pulsatile endogenous compounds.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2017, v. 44, n. 4, p. 389, doi. 10.1007/s10928-017-9526-0
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- Publication type:
- Article
Mechanism-based PK-PD model for the prolactin biological system response following an acute dopamine inhibition challenge: quantitative extrapolation to humans.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2012, v. 39, n. 5, p. 463, doi. 10.1007/s10928-012-9262-4
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- Publication type:
- Article
Gait and dynamic pedobarographic analyses in hallux rigidus patients treated with Keller's arthroplasty, arthrodesis or cheilectomy 22 years after surgery.
- Published in:
- PeerJ, 2023, p. 1, doi. 10.7717/peerj.16296
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- Publication type:
- Article
Evaluation of the Pharmacokinetics and Exposure–Response Relationship of Dapagliflozin in Patients without Diabetes and with Chronic Kidney Disease.
- Published in:
- Clinical Pharmacokinetics, 2021, v. 60, n. 4, p. 517, doi. 10.1007/s40262-020-00956-1
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- Publication type:
- Article
Sex-based differences in nuclear medicine imaging and therapy.
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- European Journal of Nuclear Medicine & Molecular Imaging, 2023, v. 50, n. 4, p. 971, doi. 10.1007/s00259-023-06113-7
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- Publication type:
- Article
Pharmacokinetics of fosfomycin in patients with prophylactic treatment for recurrent Escherichia coli urinary tract infection.
- Published in:
- 2020
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- Publication type:
- journal article
Pharmacological interactions between brivaracetam and ethanol in healthy males.
- Published in:
- 2017
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- Publication type:
- journal article
Pharmacokinetics and pharmacodynamics of oral mecamylamine - development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation.
- Published in:
- 2017
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- Publication type:
- journal article
Pharmacokinetics, pharmacodynamics and safety of CEP-26401, a high-affinity histamine-3 receptor antagonist, following single and multiple dosing in healthy subjects.
- Published in:
- 2016
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- Publication type:
- journal article
Optimizing the glutamatergic challenge model for psychosis, using S+ -ketamine to induce psychomimetic symptoms in healthy volunteers.
- Published in:
- 2015
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- Publication type:
- journal article
Optimizing the glutamatergic challenge model for psychosis, using S(+)-ketamine to induce psychomimetic symptoms in healthy volunteers.
- Published in:
- Journal of Psychopharmacology, 2015, v. 29, n. 4, p. 401, doi. 10.1177/0269881115570082
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- Publication type:
- Article