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Proteintemplat-gesteuerte Bildung eines Inhibitors des Koagulationsfaktors Xa durch eine Amidierung ohne Hintergrundreaktion.
- Published in:
- Angewandte Chemie, 2017, v. 129, n. 13, p. 3772, doi. 10.1002/ange.201611547
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- Article
The Impact of Acute Matriptase Inhibition in Hepatic Inflammatory Models.
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- BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/6306984
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- Article
Surface glycoprotein of Borna disease virus mediates virus spread from cell to cell.
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- Cellular Microbiology, 2016, v. 18, n. 3, p. 340, doi. 10.1111/cmi.12515
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- Article
Protein-Templated Formation of an Inhibitor of the Blood Coagulation Factor Xa through a Background-Free Amidation Reaction.
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- Angewandte Chemie International Edition, 2017, v. 56, n. 13, p. 3718, doi. 10.1002/anie.201611547
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- Article
NMR-Based Structural Characterization of a Two-Disulfide-Bonded Analogue of the FXIIIa Inhibitor Tridegin: New Insights into Structure–Activity Relationships.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 880, doi. 10.3390/ijms22020880
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- Article
Identification of the first synthetic inhibitors of the type II transmembrane serine protease TMPRSS2 suitable for inhibition of influenza virus activation.
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- Biochemical Journal, 2013, v. 452, n. 2, p. 331, doi. 10.1042/BJ20130101
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- Article
Front Cover: Fragment‐Based Design, Synthesis, and Characterization of Aminoisoindole‐Derived Furin Inhibitors (ChemMedChem 9/2024).
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- ChemMedChem, 2024, v. 19, n. 9, p. 1, doi. 10.1002/cmdc.202480901
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- Article
Fragment‐Based Design, Synthesis, and Characterization of Aminoisoindole‐Derived Furin Inhibitors.
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- ChemMedChem, 2024, v. 19, n. 9, p. 1, doi. 10.1002/cmdc.202400057
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- Article
Front Cover: Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors (ChemMedChem 6/2023).
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- ChemMedChem, 2023, v. 18, n. 6, p. 1, doi. 10.1002/cmdc.202300137
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- Article
Synthesis and Structural Characterization of Macrocyclic Plasmin Inhibitors.
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- ChemMedChem, 2023, v. 18, n. 6, p. 1, doi. 10.1002/cmdc.202200632
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- Article
Boroleucine‐Derived Covalent Inhibitors of the ZIKV Protease.
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- ChemMedChem, 2023, v. 18, n. 3, p. 1, doi. 10.1002/cmdc.202200336
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- Article
Structure‐Based Macrocyclization of Substrate Analogue NS2B‐NS3 Protease Inhibitors of Zika, West Nile and Dengue viruses.
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- ChemMedChem, 2020, v. 15, n. 15, p. 1439, doi. 10.1002/cmdc.202000237
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- Article
Design, Synthesis, and Characterization of Macrocyclic Inhibitors of the Proprotein Convertase Furin.
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- ChemMedChem, 2019, v. 14, n. 6, p. 673, doi. 10.1002/cmdc.201800807
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- Article
PK/PD investigation of antiviral host matriptase/TMPRSS2 inhibitors in cell models.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-67633-2
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- Article
A novel cell‐based sensor detecting the activity of individual basic proprotein convertases.
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- FEBS Journal, 2019, v. 286, n. 22, p. 4597, doi. 10.1111/febs.14979
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- Article
Synthesis and structural characterization of new macrocyclic inhibitors of the Zika virus NS2B–NS3 protease.
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- Archiv der Pharmazie, 2024, v. 357, n. 9, p. 1, doi. 10.1002/ardp.202400250
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- Article
Thermodynamic characterization of a macrocyclic Zika virus NS2B/NS3 protease inhibitor and its acyclic analogs.
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- Archiv der Pharmazie, 2023, v. 356, n. 4, p. 1, doi. 10.1002/ardp.202200518
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- Article
Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02714
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- Article
A Fluorescent-Labeled Phosphono Bisbenzguanidine As an Activity-Based Probe for Matriptase.
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- Chemistry - A European Journal, 2017, v. 23, n. 22, p. 5205, doi. 10.1002/chem.201700319
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- Article
3-Amidinophenylalanine-derived matriptase inhibitors can modulate hepcidin production in vitro.
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- Naunyn-Schmiedeberg's Archives of Pharmacology, 2020, v. 393, n. 3, p. 511, doi. 10.1007/s00210-019-01743-x
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- Article
Identification of inhibitors of the transmembrane protease FlaK of Methanococcus maripaludis.
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- MicrobiologyOpen, 2016, v. 5, n. 4, p. 637, doi. 10.1002/mbo3.358
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- Article
Time-domain in vivo near infrared fluorescence imaging for evaluation of matriptase as a potential target for the development of novel, inhibitor-based tumor therapies.
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- International Journal of Cancer, 2010, v. 127, n. 8, p. 1958, doi. 10.1002/ijc.25405
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- Article
In Vitro Evaluation of Antipseudomonal Activity and Safety Profile of Peptidomimetic Furin Inhibitors.
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- Biomedicines, 2024, v. 12, n. 9, p. 2075, doi. 10.3390/biomedicines12092075
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- Article
Antiviral Drug Candidate Repositioning for Streptococcus suis Infection in Non-Tumorigenic Cell Models.
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- Biomedicines, 2024, v. 12, n. 4, p. 783, doi. 10.3390/biomedicines12040783
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- Article
In Vitro Pharmacokinetic Behavior of Antiviral 3-Amidinophenylalanine Derivatives in Rat, Dog and Monkey Hepatocytes.
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- Biomedicines, 2023, v. 11, n. 3, p. 682, doi. 10.3390/biomedicines11030682
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- Article
Matriptase Induction of Metalloproteinase-Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms.
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- Arthritis & Rheumatology, 2017, v. 69, n. 8, p. 1601, doi. 10.1002/art.40133
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- Article
A molecular mechanism to diversify Ca<sup>2+</sup> signaling downstream of Gs protein-coupled receptors.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51991-6
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- Article
Optimization of Substrate-Analogue Furin Inhibitors.
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- ChemMedChem, 2017, v. 12, n. 23, p. 1953, doi. 10.1002/cmdc.201700596
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- Article
Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin.
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- ChemMedChem, 2017, v. 12, n. 8, p. 613, doi. 10.1002/cmdc.201700108
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- Article
Back Cover: Thrombin-Inhibiting Anticoagulant Liposomes: Development and Characterization (ChemMedChem 3/2016).
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- ChemMedChem, 2016, v. 11, n. 3, p. 350, doi. 10.1002/cmdc.201600032
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- Article
Thrombin-Inhibiting Anticoagulant Liposomes: Development and Characterization.
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- ChemMedChem, 2016, v. 11, n. 3, p. 340, doi. 10.1002/cmdc.201500489
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- Article
A Bisbenzamidine Phosphonate as a Janus-faced Inhibitor for Trypsin-like Serine Proteases.
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- ChemMedChem, 2015, v. 10, n. 10, p. 1641, doi. 10.1002/cmdc.201500319
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- Article
Novel Furin Inhibitors with Potent Anti-infectious Activity.
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- ChemMedChem, 2015, v. 10, n. 7, p. 1218, doi. 10.1002/cmdc.201500103
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- Article
Cover Picture: Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus NS2B-NS3 Protease (ChemMedChem 2/2013).
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- ChemMedChem, 2013, v. 8, n. 2, p. 173, doi. 10.1002/cmdc.201390000
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- Article
Development and Characterization of New Peptidomimetic Inhibitors of the West Nile Virus NS2B-NS3 Protease.
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- ChemMedChem, 2013, v. 8, n. 2, p. 231, doi. 10.1002/cmdc.201200497
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- Article
Beyond Heparinization: Design of Highly Potent Thrombin Inhibitors Suitable for Surface Coupling.
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- ChemMedChem, 2012, v. 7, n. 11, p. 1965, doi. 10.1002/cmdc.201200292
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- Article
Synthesis and Functional Characterization of Tridegin and Its Analogues: Inhibitors and Substrates of Factor XIIIa.
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- ChemMedChem, 2012, v. 7, n. 2, p. 326, doi. 10.1002/cmdc.201100405
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- Article
Insights into Matriptase-2 Substrate Binding and Inhibition Mechanisms by Analyzing Active-Site-Mutated Variants.
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- ChemMedChem, 2012, v. 7, n. 1, p. 68, doi. 10.1002/cmdc.201100350
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- Article
Inside Cover: Insights into Matriptase-2 Substrate Binding and Inhibition Mechanisms by Analyzing Active-Site-Mutated Variants (ChemMedChem 1/2012).
- Published in:
- ChemMedChem, 2012, v. 7, n. 1, p. 2, doi. 10.1002/cmdc.201190061
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- Article
Highly Potent and Selective Substrate Analogue Factor Xa Inhibitors Containing D-Homophenylalanine Analogues as P3 Residue: Part 2.
- Published in:
- ChemMedChem, 2007, v. 2, n. 7, p. 1043, doi. 10.1002/cmdc.200700031
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- Publication type:
- Article
Limiting the Number of Potential Binding Modes by Introducing Symmetry into Ligands: Structure-Based Design of Inhibitors for Trypsin-Like Serine Proteases.
- Published in:
- Chemistry - A European Journal, 2016, v. 22, n. 2, p. 610, doi. 10.1002/chem.201503534
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- Publication type:
- Article
Interspecies Comparisons of the Effects of Potential Antiviral 3-Amidinophenylalanine Derivatives on Cytochrome P450 1A2 Isoenzyme.
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- Veterinary Sciences, 2022, v. 9, n. 4, p. N.PAG, doi. 10.3390/vetsci9040156
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- Article
Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues.
- Published in:
- Biological Chemistry, 2014, v. 395, n. 7/8, p. 891, doi. 10.1515/hsz-2014-0158
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- Publication type:
- Article
Purification of the proprotein convertase furin by affinity chromatography based on PC-specific inhibitors.
- Published in:
- Biological Chemistry, 2011, v. 392, n. 11, p. 973, doi. 10.1515/BC.2011.100
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- Article
Increase of Anti-Metastatic Efficacy by Selectivity-But Not Affinity-Optimization of Synthetic Serine Protease Inhibitors.
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- Biological Chemistry, 2003, v. 384, n. 10/11, p. 1515, doi. 10.1515/BC.2003.168
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- Article
Potent Photoaffinity Labelled and Iodinated Antagonists of Bradykinin.
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- Biological Chemistry, 1995, v. 376, n. 1, p. 33
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- Article
New Photoaffinity Labelled Agonists of Bradykinin.
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- Biological Chemistry, 1995, v. 376, n. 1, p. 25
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- Article
Dipeptidyl Peptidase IV in the Immune System.
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- Biological Chemistry, 1991, v. 372, n. 1, p. 305
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- Article