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Assessment of individual molecular response in chronic myeloid leukemia patients with atypical BCR-ABL1 fusion transcripts: recommendations by the EUTOS cooperative network.
- Published in:
- Journal of Cancer Research & Clinical Oncology, 2021, v. 147, n. 10, p. 3081, doi. 10.1007/s00432-021-03569-8
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- Publication type:
- Article
Next-generation deep sequencing improves detection of BCR- ABL1 kinase domain mutations emerging under tyrosine kinase inhibitor treatment of chronic myeloid leukemia patients in chronic phase.
- Published in:
- Journal of Cancer Research & Clinical Oncology, 2015, v. 141, n. 5, p. 887, doi. 10.1007/s00432-014-1845-6
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- Publication type:
- Article
Identification of Two DNMT3A Mutations Compromising Protein Stability and Methylation Capacity in Acute Myeloid Leukemia.
- Published in:
- Journal of Oncology, 2019, p. 1, doi. 10.1155/2019/5985923
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- Publication type:
- Article
Next-generation sequencing for BCR-ABL1 kinase domain mutation testing in patients with chronic myeloid leukemia: a position paper.
- Published in:
- Journal of Hematology & Oncology, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13045-019-0815-5
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- Publication type:
- Article
Treatment and monitoring of Philadelphia chromosome-positive leukemia patients: recent advances and remaining challenges.
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- Journal of Hematology & Oncology, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13045-019-0729-2
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- Publication type:
- Article
Targeting Leukemic Stem Cells in Chronic Myeloid Leukemia: Is It Worth the Effort?
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- International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 7093, doi. 10.3390/ijms22137093
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- Publication type:
- Article
The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 6857, doi. 10.3390/ijms22136857
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- Publication type:
- Article
Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2983, doi. 10.3390/ijms22062983
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- Publication type:
- Article
Non-Coding RNA Signatures of B-Cell Acute Lymphoblastic Leukemia.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2683, doi. 10.3390/ijms22052683
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- Publication type:
- Article
Recent Advances in the Molecular Biology of Systemic Mastocytosis: Implications for Diagnosis, Prognosis, and Therapy.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 3987, doi. 10.3390/ijms21113987
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- Publication type:
- Article
Mechanisms of Disease Progression and Resistance to Tyrosine Kinase Inhibitor Therapy in Chronic Myeloid Leukemia: An Update.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 24, p. 6141, doi. 10.3390/ijms20246141
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- Publication type:
- Article
The clonal evolution of two distinct T315I-positive BCR-ABL1 subclones in a Philadelphia-positive acute lymphoblastic leukemia failing multiple lines of therapy: a case report.
- Published in:
- 2017
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- Publication type:
- journal article
Molecular Testing in CML between Old and New Methods: Are We at a Turning Point?
- Published in:
- Journal of Clinical Medicine, 2020, v. 9, n. 12, p. 3865, doi. 10.3390/jcm9123865
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- Publication type:
- Article
Chronic Myeloid Leukemia Prognosis and Therapy: Criticisms and Perspectives.
- Published in:
- 2020
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- Publication type:
- Editorial
Systemic Mastocytosis: Molecular Landscape and Implications for Treatment.
- Published in:
- Mediterranean Journal of Hematology & Infectious Diseases, 2021, v. 13, n. 1, p. 1, doi. 10.4084/MJHID.2021.046
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- Publication type:
- Article
Nilotinib: a novel encouraging therapeutic option for chronic myeloid leukemia patients with imatinib resistance or intolerance.
- Published in:
- Biologics: Targets & Therapy, 2007, v. 1, n. 2, p. 121
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- Publication type:
- Article
Next‐generation sequencing improves BCR‐ABL1 mutation detection in Philadelphia chromosome‐positive acute lymphoblastic leukaemia.
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- British Journal of Haematology, 2021, v. 193, n. 2, p. 271, doi. 10.1111/bjh.17301
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- Publication type:
- Article
Present and future of molecular monitoring in chronic myeloid leukaemia.
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- British Journal of Haematology, 2016, v. 173, n. 3, p. 337, doi. 10.1111/bjh.13966
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- Publication type:
- Article
Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing.
- Published in:
- Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0363-8
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- Publication type:
- Article
Unstable major molecular response as a trigger for next generation sequencing‐based BCR::ABL1 mutation testing in chronic myeloid leukemia.
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- American Journal of Hematology, 2024, v. 99, n. 4, p. 759, doi. 10.1002/ajh.27232
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- Publication type:
- Article
14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia.
- Published in:
- PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131074
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- Publication type:
- Article
BCR-ABL1-Associated Reduction of Beta Catenin Antagonist Chibby1 in Chronic Myeloid Leukemia.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0081425
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- Publication type:
- Article
IKAROS Deletions Dictate a Unique Gene Expression Signature in Patients with Adult B-Cell Acute Lymphoblastic Leukemia.
- Published in:
- PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040934
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- Publication type:
- Article
In chronic myeloid leukemia patients on second-line tyrosine kinase inhibitor therapy, deep sequencing of BCR-ABL1 at the time of warning may allow sensitive detection of emerging drug-resistant mutants.
- Published in:
- 2016
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- Publication type:
- journal article
Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy.
- Published in:
- Molecular Cancer, 2018, v. 17, p. 1, doi. 10.1186/s12943-018-0780-6
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- Publication type:
- Article
SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted.
- Published in:
- Biomarker Research, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40364-023-00468-7
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- Publication type:
- Article
Resistance to Tyrosine Kinase Inhibitors in Philadelphia Chromosome–Positive Leukemias: Which Mutations Matter?
- Published in:
- Clinical Cancer Update, 2007, v. 1, n. 1, p. 79, doi. 10.3816/CCU.2007.n.013
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- Publication type:
- Article
Next‐generation sequencing for BCR‐ABL1 kinase domain mutations in adult patients with Philadelphia chromosome‐positive acute lymphoblastic leukemia: A position paper.
- Published in:
- Cancer Medicine, 2020, v. 9, n. 9, p. 2960, doi. 10.1002/cam4.2946
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- Publication type:
- Article
Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.728613
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- Publication type:
- Article
Letter to the Editor Dose increase of imatinib mesylate may overcome acquired resistance in bcr/abl-positive acute lymphoid leukaemia.
- Published in:
- 2004
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- Publication type:
- Letter
FOXM1 Transcription Factor: A New Component of Chronic Myeloid Leukemia Stem Cell Proliferation Advantage.
- Published in:
- Journal of Cellular Biochemistry, 2017, v. 118, n. 11, p. 3968, doi. 10.1002/jcb.26052
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- Publication type:
- Article
MPN-180: A Novel Mechanism of Action of Midostaurin in Systemic Mastocytosis: Beyond KIT Inhibition.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S356, doi. 10.1016/S2152-2650(21)01823-1
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- Publication type:
- Article
AML-269: The Anti-Leukemic Effects of the Pan-Aurora Inhibitor Tozasertib Are Negatively Influenced by Hypoxia in Acute Myeloid Leukemia.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S297, doi. 10.1016/S2152-2650(21)01708-0
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- Publication type:
- Article
Poster: MPN-180: A Novel Mechanism of Action of Midostaurin in Systemic Mastocytosis: Beyond KIT Inhibition.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S233, doi. 10.1016/S2152-2650(21)01468-3
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- Publication type:
- Article
Poster: AML-269: The Anti-Leukemic Effects of the Pan-Aurora Inhibitor Tozasertib Are Negatively Influenced by Hypoxia in Acute Myeloid Leukemia.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S215, doi. 10.1016/S2152-2650(21)01351-3
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- Publication type:
- Article
Molecular Testing of CML Patients in 2021: Between Old and New Tools.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S63, doi. 10.1016/S2152-2650(21)01212-X
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- Publication type:
- Article
Impact of Arterial Thrombotic Events on the Outcome of Chronic Myeloid Leukemia Patients Treated with Nilotinib First-Line: A GIMEMA CML WP Analysis.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. S313, doi. 10.1016/j.clml.2017.07.114
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- Publication type:
- Article
Establishing a National Network of Laboratories Using Next Generation Amplicon Deep Sequencing for BCR-ABL1 Kinase Domain Mutation Screening in Philadelphia Chromosome-Positive Leukemias: the ‘NEXT-IN-CML' Study.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2017, v. 17, p. S310, doi. 10.1016/j.clml.2017.07.110
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- Publication type:
- Article
Blinatumomab is Safe and Effective in Relapsed and MRD Positive B-ALL CD19+ Patients: the Bologna Compassionate Program Experience.
- Published in:
- Clinical Lymphoma, Myeloma & Leukemia, 2016, v. 16, p. S14, doi. 10.1016/j.clml.2016.07.022
- By:
- Publication type:
- Article
Mutations in the BCR-ABL1 Kinase Domain and Elsewhere in Chronic Myeloid Leukemia.
- Published in:
- 2015
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- Publication type:
- journal article
Sequential development of mutant clones in an imatinib resistant chronic myeloid leukaemia patient following sequential treatment with multiple tyrosine kinase inhibitors: an emerging problem?
- Published in:
- Cancer Chemotherapy & Pharmacology, 2009, v. 64, n. 1, p. 195, doi. 10.1007/s00280-008-0905-5
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- Publication type:
- Article
Ponatinib as a Valid Alternative Strategy in Patients with Blast Crisis-Chronic Myeloid Leukemia Not Eligible for Allogeneic Stem Cells Transplantation and/or Conventional Chemotherapy: Report of a Case.
- Published in:
- Case Reports in Hematology, 2017, p. 1, doi. 10.1155/2017/6167345
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- Publication type:
- Article
Interferon-α Revisited: Individualized Treatment Management Eased the Selective Pressure of Tyrosine Kinase Inhibitors on BCR-ABL1 Mutations Resulting in a Molecular Response in High-Risk CML Patients.
- Published in:
- PLoS ONE, 2016, v. 11, n. 5, p. 1, doi. 10.1371/journal.pone.0155959
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- Publication type:
- Article
Comparison between indolent systemic mastocytosis and clonal mast cell disease not meeting WHO diagnostic criteria: A nationwide multicenter retrospective analysis.
- Published in:
- Hematological Oncology, 2024, v. 42, n. 3, p. 1, doi. 10.1002/hon.3277
- By:
- Publication type:
- Article
Inotuzumab ozogamicin and donor lymphocyte infusion is a safe and promising combination in relapsed acute lymphoblastic leukemia after allogeneic stem cell transplant.
- Published in:
- Hematological Oncology, 2021, v. 39, n. 4, p. 580, doi. 10.1002/hon.2886
- By:
- Publication type:
- Article
Ponatinib treatment in chronic myeloid leukemia cell lines targets aurora kinase A/FOXM1 axis.
- Published in:
- 2020
- By:
- Publication type:
- Letter
What are the challenges in 2016 regarding resistance to tyrosine kinase inhibitors in chronic myeloid leukemia and cancer?
- Published in:
- 2017
- By:
- Publication type:
- journal article
Monitoring minimal residual disease and controlling drug resistance in chronic myeloid leukaemia patients in treatment with imatinib as a guide to clinical management.
- Published in:
- Hematological Oncology, 2006, v. 24, n. 4, p. 196, doi. 10.1002/hon.792
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- Publication type:
- Article
Long term outcome of Ph+ CML patients achieving complete cytogenetic remission with interferon based therapy moving from interferon to imatinib era.
- Published in:
- American Journal of Hematology, 2014, v. 89, n. 2, p. 119, doi. 10.1002/ajh.23593
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- Publication type:
- Article
Pharmacological Inhibition of WIP1 Sensitizes Acute Myeloid Leukemia Cells to the MDM2 Inhibitor Nutlin-3a.
- Published in:
- Biomedicines, 2021, v. 9, n. 4, p. 388, doi. 10.3390/biomedicines9040388
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- Publication type:
- Article