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Rational Design and Identification of a Non-Peptidic Aggregation Inhibitor of Amyloid-β Based on a Pharmacophore Motif Obtained from cyclo[-Lys-Leu-Val-Phe-Phe-].
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 31, p. 8236, doi. 10.1002/anie.201405109
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- Publication type:
- Article
Serine-Selective Aerobic Cleavage of Peptides and a Protein Using a Water-Soluble Copper-Organoradical Conjugate.
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 25, p. 6501, doi. 10.1002/anie.201402618
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- Publication type:
- Article
Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation.
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 5, p. 1382, doi. 10.1002/anie.201308001
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- Publication type:
- Article
Photo-oxygenation by a biocompatible catalyst reduces amyloid-β levels in Alzheimer's disease mice.
- Published in:
- 2021
- By:
- Publication type:
- journal article
P2‐059: PHOTOOXYGENATION BY BIOCOMPATIBLE CATALYST REDUCES THE Aβ LEVEL IN THE BRAINS OF ALZHEIMER DISEASE MODEL MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P594, doi. 10.1016/j.jalz.2019.06.2466
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- Publication type:
- Article
Promotion in the Clearance of Aggregated Aβ In Vivo Using Amyloid Selective Photo-Oxygenation Technology.
- Published in:
- Neuroscience Insights, 2022, p. 1, doi. 10.1177/26331055221126179
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- Publication type:
- Article
Rational Design and Identification of a Non-Peptidic Aggregation Inhibitor of Amyloid-_ Based on a Pharmacophore Motif Obtained from cyclo[-Lys-Leu-Val-Phe-Phe-].
- Published in:
- Angewandte Chemie, 2014, v. 126, n. 31, p. 8375, doi. 10.1002/ange.201405109
- By:
- Publication type:
- Article
Serine-Selective Aerobic Cleavage of Peptides and a Protein Using a Water-Soluble Copper-Organoradical Conjugate.
- Published in:
- Angewandte Chemie, 2014, v. 126, n. 25, p. 6619, doi. 10.1002/ange.201402618
- By:
- Publication type:
- Article
Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation.
- Published in:
- Angewandte Chemie, 2014, v. 126, n. 5, p. 1406, doi. 10.1002/ange.201308001
- By:
- Publication type:
- Article
Titelbild: Design and Folding of [Glu<sup>A4</sup>(O<sup>β</sup>Thr<sup>B30</sup>)]Insulin ('Ester Insulin'): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin (Angew. Chem. 32/2010).
- Published in:
- Angewandte Chemie, 2010, v. 122, n. 32, p. 5517, doi. 10.1002/ange.201002659
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- Publication type:
- Article
Design and Folding of [Glu<sup>A4</sup>(O<sup>β</sup>Thr<sup>B30</sup>)]Insulin ('Ester Insulin'): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin.
- Published in:
- Angewandte Chemie, 2010, v. 122, n. 32, p. 5621, doi. 10.1002/ange.201001151
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- Publication type:
- Article
Modular synthetic strategy for N/C‐terminal protected amyloidogenic peptides.
- Published in:
- Journal of Peptide Science, 2024, v. 30, n. 3, p. 1, doi. 10.1002/psc.3546
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- Publication type:
- Article
Synthesis of O-Acyl Isopeptides.
- Published in:
- Chemical Record, 2013, v. 13, n. 2, p. 218, doi. 10.1002/tcr.201200023
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- Publication type:
- Article
O-Acyl isopeptide method: development of an O-acyl isodipeptide unit for Boc SPPS and its application to the synthesis of A β1-42 isopeptide.
- Published in:
- Journal of Peptide Science, 2014, v. 20, n. 9, p. 669, doi. 10.1002/psc.2662
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- Publication type:
- Article
Synthesis of an O-acyl isopeptide by using native chemical ligation in an aqueous solvent system.
- Published in:
- Journal of Peptide Science, 2014, v. 20, n. 5, p. 361, doi. 10.1002/psc.2622
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- Publication type:
- Article
Through the looking glass - a new world of proteins enabled by chemical synthesis.
- Published in:
- Journal of Peptide Science, 2012, v. 18, n. 7, p. 428, doi. 10.1002/psc.2421
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- Publication type:
- Article
Epimerization-free synthesis of cyclic peptide by use of the O-acyl isopeptide method.
- Published in:
- Journal of Peptide Science, 2010, v. 16, n. 8, p. 437, doi. 10.1002/psc.1261
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- Publication type:
- Article
' O-Acyl isopeptide method' for peptide synthesis: Solvent effects in the synthesis of Aβ1-42 isopeptide using ' O-acyl isodipeptide unit'.
- Published in:
- Journal of Peptide Science, 2007, v. 13, n. 12, p. 868, doi. 10.1002/psc.905
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- Publication type:
- Article
'Click peptide': a novel ' O-acyl isopeptide method' for peptide synthesis and chemical biology-oriented synthesis of amyloid β peptide analogues.
- Published in:
- Journal of Peptide Science, 2006, v. 12, n. 12, p. 823, doi. 10.1002/psc.817
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- Publication type:
- Article
The ' O-acyl isopeptide method' for the synthesis of difficult sequence-containing peptides: application to the synthesis of Alzheimer's disease-related amyloid β peptide (Aβ) 1-42.
- Published in:
- Journal of Peptide Science, 2005, v. 11, n. 8, p. 441, doi. 10.1002/psc.649
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- Publication type:
- Article
Photo-Oxygenation as a New Therapeutic Strategy for Neurodegenerative Proteinopathies by Enhancing the Clearance of Amyloid Proteins.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.945017
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- Publication type:
- Article
A Cyclic KLVFF-Derived Peptide Aggregation Inhibitor Induces the Formation of Less-Toxic Off-Pathway Amyloid-β Oligomers.
- Published in:
- ChemBioChem, 2014, v. 15, n. 17, p. 2577, doi. 10.1002/cbic.201402430
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- Publication type:
- Article
Click Peptide Concept: O-Acyl Isopeptide of Islet Amyloid Polypeptide as a Nonaggregative Precursor Molecule.
- Published in:
- ChemBioChem, 2011, v. 12, n. 8, p. 1216, doi. 10.1002/cbic.201100025
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- Publication type:
- Article
Leuco Ethyl Violet as Self‐Activating Prodrug Photocatalyst for In Vivo Amyloid‐Selective Oxygenation.
- Published in:
- Advanced Science, 2024, v. 11, n. 26, p. 1, doi. 10.1002/advs.202401346
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- Publication type:
- Article
Photo-oxygenation of histidine residue inhibits α-synuclein aggregation.
- Published in:
- FASEB Journal, 2023, v. 37, n. 12, p. 1, doi. 10.1096/fj.202301533R
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- Publication type:
- Article
S-acyl isopeptide method: Use of allyl-type protective group for improved preparation of thioester-containing S-acyl isopeptides by Fmoc-based SPPS.
- Published in:
- Biopolymers, 2011, v. 96, n. 2, p. 228, doi. 10.1002/bip.21410
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- Publication type:
- Article
Development of O-acyl isopeptide method.
- Published in:
- Biopolymers, 2007, v. 88, n. 2, p. 253, doi. 10.1002/bip.20683
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- Publication type:
- Article
ON intramolecular acyl migration reaction in the development of prodrugs and the synthesis of difficult sequence-containing bioactive peptides.
- Published in:
- Biopolymers, 2004, v. 76, n. 4, p. 344, doi. 10.1002/bip.20136
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- Publication type:
- Article
'Click Peptide': pH-Triggered in Situ Production and Aggregation of Monomer Aβ1-42.
- Published in:
- ChemBioChem, 2009, v. 10, n. 4, p. 710, doi. 10.1002/cbic.200800765
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- Publication type:
- Article
Controlled Production of Amyloid β Peptide from a Photo-Triggered, Water-Soluble Precursor 'Click Peptide'.
- Published in:
- ChemBioChem, 2008, v. 9, n. 18, p. 3055, doi. 10.1002/cbic.200800503
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- Publication type:
- Article
“Click Peptides”—Chemical Biology-Oriented Synthesis of Alzheimer's Disease-Related Amyloid β Peptide (Aβ) Analogues Based on the “O-Acyl Isopeptide Method”.
- Published in:
- ChemBioChem, 2006, v. 7, n. 10, p. 1549, doi. 10.1002/cbic.200600112
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- Publication type:
- Article
Design and Folding of [Glu<sup>A4</sup>(O<sup>β</sup>Thr<sup>B30</sup>)]Insulin ('Ester Insulin'): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin.
- Published in:
- Angewandte Chemie International Edition, 2010, v. 49, n. 32, p. 5489, doi. 10.1002/anie.201001151
- By:
- Publication type:
- Article
Cover Picture: Design and Folding of [Glu<sup>A4</sup>(O<sup>β</sup>Thr<sup>B30</sup>)]Insulin ('Ester Insulin'): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin (Angew. Chem. Int. Ed. 32/2010).
- Published in:
- Angewandte Chemie International Edition, 2010, v. 49, n. 32, p. 5389, doi. 10.1002/anie.201002659
- By:
- Publication type:
- Article
Comparative Properties of Insulin-like Growth Factor 1 (IGF-1) and [Gly7D-Ala]IGF-1 Prepared by Total Chemical Synthesis.
- Published in:
- Angewandte Chemie International Edition, 2008, v. 47, n. 6, p. 1102, doi. 10.1002/anie.200703521
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- Publication type:
- Article