Found: 12
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Two‐Part Phase 1 Multiple‐Ascending‐Dose Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of TRV734 in Healthy Adults.
- Published in:
- Clinical Pharmacology in Drug Development, 2022, v. 11, n. 1, p. 51, doi. 10.1002/cpdd.1016
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- Publication type:
- Article
A First‐in‐Human Clinical Study With TRV734, an Orally Bioavailable G‐Protein–Biased Ligand at the μ‐Opioid Receptor.
- Published in:
- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 2, p. 256, doi. 10.1002/cpdd.721
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- Publication type:
- Article
APOLLO-1: a randomized placebo and active-controlled phase III study investigating oliceridine (TRV130), a G protein-biased ligand at the µ-opioid receptor, for management of moderate-to-severe acute pain following bunionectomy.
- Published in:
- Journal of Pain Research, 2019, v. 12, p. 927, doi. 10.2147/JPR.S171013
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- Publication type:
- Article
A randomized, Phase IIb study investigating oliceridine (TRV130), a novel µ-receptor G-protein pathway selective (µ-GPS) modulator, for the management of moderate to severe acute pain following abdominoplasty.
- Published in:
- Journal of Pain Research, 2017, v. 10, p. 2413, doi. 10.2147/jpr.s137952
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- Publication type:
- Article
APOLLO‐2: A Randomized, Placebo and Active‐Controlled Phase III Study Investigating Oliceridine (TRV130), a G Protein–Biased Ligand at the μ‐Opioid Receptor, for Management of Moderate to Severe Acute Pain Following Abdominoplasty
- Published in:
- Pain Practice, 2019, v. 19, n. 7, p. 715, doi. 10.1111/papr.12801
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- Publication type:
- Article
Is plasma renin activity associated with worse outcomes in acute heart failure? A secondary analysis from the BLAST-AHF trial.
- Published in:
- 2019
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- Publication type:
- journal article
First Clinical Experience With TRV130: Pharmacokinetics and Pharmacodynamics in Healthy Volunteers.
- Published in:
- Journal of Clinical Pharmacology, 2014, v. 54, n. 3, p. 351, doi. 10.1002/jcph.207
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- Publication type:
- Article
First Clinical Experience with TRV027: Pharmacokinetics and Pharmacodynamics in Healthy Volunteers.
- Published in:
- Journal of Clinical Pharmacology, 2013, v. 53, n. 9, p. 892, doi. 10.1002/jcph.111
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- Publication type:
- Article
Oliceridine, a Novel G Protein-Biased Ligand at the μ-Opioid Receptor,Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. II: Simulation of Potential Phase 3 Study Designs Using a Pharmacokinetic/Pharmacodynamic Model Michael
- Published in:
- Journal of Clinical Pharmacology, 2018, v. 58, n. 6, p. 762, doi. 10.1002/jcph.1075
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- Publication type:
- Article
Oliceridine (TRV130), a Novel G Protein-Biased Ligand at the μ-Opioid Receptor,Demonstrates a Predictable Relationship Between Plasma Concentrations and Pain Relief. I: Development of a Pharmacokinetic/Pharmacodynamic Model.
- Published in:
- Journal of Clinical Pharmacology, 2018, v. 58, n. 6, p. 750, doi. 10.1002/jcph.1076
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- Publication type:
- Article
Relationship between baseline systolic blood pressure and long-term outcomes in acute heart failure patients treated with TRV027: an exploratory subgroup analysis of BLAST-AHF.
- Published in:
- Clinical Research in Cardiology, 2018, v. 107, n. 2, p. 170, doi. 10.1007/s00392-017-1168-0
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- Publication type:
- Article
Biased ligand of the angiotensin II type 1 receptor in patients with acute heart failure: a randomized, double-blind, placebo-controlled, phase IIB, dose ranging trial (BLAST-AHF).
- Published in:
- European Heart Journal, 2017, v. 38, n. 30, p. 2364, doi. 10.1093/eurheartj/ehx196
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- Publication type:
- Article