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Machine learning in sudden cardiac death risk prediction: a systematic review.
Published in:
2022
By:
- Barker, Joseph;
- Li, Xin;
- Khavandi, Sarah;
- Koeckerling, David;
- Mavilakandy, Akash;
- Pepper, Coral;
- Bountziouka, Vasiliki;
- Chen, Long;
- Kotb, Ahmed;
- Antoun, Ibrahim;
- Mansir, John;
- Smith-Byrne, Karl;
- Schlindwein, Fernando S;
- Dhutia, Harshil;
- Tyukin, Ivan;
- Nicolson, William B;
- Ng, G Andre
Publication type:
journal article
Genetic susceptibility, elevated blood pressure, and risk of atrial fibrillation: a Mendelian randomization study.
Published in:
Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00849-3
By:
- Nazarzadeh, Milad;
- Pinho-Gomes, Ana-Catarina;
- Bidel, Zeinab;
- Canoy, Dexter;
- Dehghan, Abbas;
- Smith Byrne, Karl;
- Bennett, Derrick A.;
- Smith, George Davey;
- Rahimi, Kazem
Publication type:
Article
Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43485-8
By:
- Mälarstig, Anders;
- Grassmann, Felix;
- Dahl, Leo;
- Dimitriou, Marios;
- McLeod, Dianna;
- Gabrielson, Marike;
- Smith-Byrne, Karl;
- Thomas, Cecilia E.;
- Huang, Tzu-Hsuan;
- Forsberg, Simon K. G.;
- Eriksson, Per;
- Ulfstedt, Mikael;
- Johansson, Mattias;
- Sokolov, Aleksandr V.;
- Schiöth, Helgi B.;
- Hall, Per;
- Schwenk, Jochen M.;
- Czene, Kamila;
- Hedman, Åsa K.
Publication type:
Article
Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer.
Published in:
Cancer Causes & Control, 2022, v. 33, n. 5, p. 631, doi. 10.1007/s10552-022-01562-1
By:
- Wade, Kaitlin H.;
- Yarmolinsky, James;
- Giovannucci, Edward;
- Lewis, Sarah J.;
- Millwood, Iona Y.;
- Munafò, Marcus R.;
- Meddens, Fleur;
- Burrows, Kimberley;
- Bell, Joshua A.;
- Davies, Neil M.;
- Mariosa, Daniela;
- Kanerva, Noora;
- Vincent, Emma E.;
- Smith-Byrne, Karl;
- Guida, Florence;
- Gunter, Marc J.;
- Sanderson, Eleanor;
- Dudbridge, Frank;
- Burgess, Stephen;
- Cornelis, Marilyn C.
Publication type:
Article
Prediagnosis Leisure-Time Physical Activity and Lung Cancer Survival: A Pooled Analysis of 11 Cohorts.
Published in:
JNCI Cancer Spectrum, 2022, v. 6, n. 2, p. 1, doi. 10.1093/jncics/pkac009
By:
- Yang, Jae Jeong;
- Yu, Danxia;
- White, Emily;
- Lee, Dong Hoon;
- Blot, William;
- Robien, Kim;
- Sinha, Rashmi;
- Park, Yikyung;
- Takata, Yumie;
- Gao, Yu-Tang;
- Smith-Byrne, Karl;
- Monninkhof, Evelyn M;
- Kaaks, Rudolf;
- Langhammer, Arnulf;
- Borch, Kristin Benjaminsen;
- Al-Shaar, Laila;
- Lan, Qing;
- Sørgjerd, Elin Pettersen;
- Zhang, Xuehong;
- Zhu, Clair
Publication type:
Article
GWAS identifies 14 loci for device-measured physical activity and sleep duration.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07743-4
By:
- Doherty, Aiden;
- Smith-Byrne, Karl;
- Ferreira, Teresa;
- Holmes, Michael V.;
- Holmes, Chris;
- Pulit, Sara L.;
- Lindgren, Cecilia M.
Publication type:
Article
Serum Extracellular Vesicle-Derived microRNAs as Potential Biomarkers for Pleural Mesothelioma in a European Prospective Study.
Published in:
Cancers, 2023, v. 15, n. 1, p. 125, doi. 10.3390/cancers15010125
By:
- Casalone, Elisabetta;
- Birolo, Giovanni;
- Pardini, Barbara;
- Allione, Alessandra;
- Russo, Alessia;
- Catalano, Chiara;
- Mencoboni, Manlio;
- Ferrante, Daniela;
- Magnani, Corrado;
- Sculco, Marika;
- Dianzani, Irma;
- Grosso, Federica;
- Mirabelli, Dario;
- Filiberti, Rosa Angela;
- Rena, Ottavio;
- Sacerdote, Carlotta;
- Rodriguez-Barranco, Miguel;
- Smith-Byrne, Karl;
- Panico, Salvatore;
- Agnoli, Claudia
Publication type:
Article
Genetic predisposition to metabolically unfavourable adiposity and prostate cancer risk: A Mendelian randomization analysis.
Published in:
Cancer Medicine, 2023, v. 12, n. 15, p. 16482, doi. 10.1002/cam4.6220
By:
- Perez‐Cornago, Aurora;
- Smith‐Byrne, Karl;
- Hazelwood, Emma;
- Watling, Cody Z.;
- Martin, Susan;
- Frayling, Timothy;
- Lewis, Sarah;
- Martin, Richard M.;
- Yaghootkar, Hanieh;
- Travis, Ruth C.;
- Key, Timothy J.
Publication type:
Article
Association of germline TYK2 variation with lung cancer and non‐Hodgkin lymphoma risk.
Published in:
International Journal of Cancer, 2022, v. 151, n. 12, p. 2155, doi. 10.1002/ijc.34180
By:
- Yarmolinsky, James;
- Amos, Christopher I.;
- Hung, Rayjean J.;
- Moreno, Victor;
- Burrows, Kimberley;
- Smith‐Byrne, Karl;
- Atkins, Joshua R.;
- Brennan, Paul;
- McKay, James D.;
- Martin, Richard M.;
- Davey Smith, George
Publication type:
Article
Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia.
Published in:
International Journal of Cancer, 2022, v. 151, n. 7, p. 1033, doi. 10.1002/ijc.34116
By:
- Watts, Eleanor L.;
- Perez‐Cornago, Aurora;
- Fensom, Georgina K.;
- Smith‐Byrne, Karl;
- Noor, Urwah;
- Andrews, Colm D.;
- Gunter, Marc J.;
- Holmes, Michael V.;
- Martin, Richard M.;
- Tsilidis, Konstantinos K.;
- Albanes, Demetrius;
- Barricarte, Aurelio;
- Bueno‐de‐Mesquita, Bas;
- Chen, Chu;
- Cohn, Barbara A.;
- Dimou, Niki L.;
- Ferrucci, Luigi;
- Flicker, Leon;
- Freedman, Neal D.;
- Giles, Graham G.
Publication type:
Article
Correction: Accelerometer measured physical activity and the incidence of cardiovascular disease: Evidence from the UK Biobank cohort study.
Published in:
2021
By:
- Ramakrishnan, Rema;
- Doherty, Aiden;
- Smith-Byrne, Karl;
- Rahimi, Kazem;
- Bennett, Derrick;
- Woodward, Mark;
- Walmsley, Rosemary;
- Dwyer, Terence
Publication type:
Correction Notice
The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.
Published in:
2021
By:
- Guida, Florence;
- Tan, Vanessa Y.;
- Corbin, Laura J.;
- Smith-Byrne, Karl;
- Alcala, Karine;
- Langenberg, Claudia;
- Stewart, Isobel D.;
- Butterworth, Adam S.;
- Surendran, Praveen;
- Achaintre, David;
- Adamski, Jerzy;
- Amiano Exezarreta, Pilar;
- Bergmann, Manuela M.;
- Bull, Caroline J.;
- Dahm, Christina C.;
- Gicquiau, Audrey;
- Giles, Graham G.;
- Gunter, Marc J.;
- Haller, Toomas;
- Langhammer, Arnulf
Publication type:
journal article
Common genetic variations in telomere length genes and lung cancer: a Mendelian randomisation study and its novel application in lung tumour transcriptome.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.83118
By:
- Cardoso Penha, Ricardo Cortez;
- Smith-Byrne, Karl;
- Atkins, Joshua R.;
- Haycock, Philip C.;
- Kar, Siddhartha;
- Codd, Veryan;
- Samani, Nilesh J.;
- Nelson, Christopher;
- Milojevic, Maja;
- Gabriel, Aurélie A. G.;
- Amos, Christopher;
- Brennan, Paul;
- Hung, Rayjean J.;
- Kachuri, Linda;
- Mckay, James D.
Publication type:
Article
Circulating insulin‐like growth factor‐I, total and free testosterone concentrations and prostate cancer risk in 200 000 men in UK Biobank.
Published in:
International Journal of Cancer, 2021, v. 148, n. 9, p. 2274, doi. 10.1002/ijc.33416
By:
- Watts, Eleanor L.;
- Fensom, Georgina K.;
- Smith Byrne, Karl;
- Perez‐Cornago, Aurora;
- Allen, Naomi E.;
- Knuppel, Anika;
- Gunter, Marc J.;
- Holmes, Michael V.;
- Martin, Richard M.;
- Murphy, Neil;
- Tsilidis, Konstantinos K.;
- Yeap, Bu B.;
- Key, Timothy J.;
- Travis, Ruth C.
Publication type:
Article
Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study.
Published in:
British Journal of Cancer, 2024, v. 130, n. 1, p. 114, doi. 10.1038/s41416-023-02489-3
By:
- Watts, Eleanor L.;
- Gonzales, Tomas I.;
- Strain, Tessa;
- Saint-Maurice, Pedro F.;
- Bishop, D. Timothy;
- Chanock, Stephen J.;
- Johansson, Mattias;
- Keku, Temitope O.;
- Le Marchand, Loic;
- Moreno, Victor;
- Newcomb, Polly A.;
- Newton, Christina C.;
- Pai, Rish K.;
- Purdue, Mark P.;
- Ulrich, Cornelia M.;
- Smith-Byrne, Karl;
- Van Guelpen, Bethany;
- Eeles, Rosalind A.;
- Haiman, Christopher A.;
- Kote-Jarai, Zsofia
Publication type:
Article
Accelerometer measured physical activity and the incidence of cardiovascular disease: Evidence from the UK Biobank cohort study.
Published in:
2021
By:
- Ramakrishnan, Rema;
- Doherty, Aiden;
- Smith-Byrne, Karl;
- Rahimi, Kazem;
- Bennett, Derrick;
- Woodward, Mark;
- Walmsley, Rosemary;
- Dwyer, Terence
Publication type:
journal article
Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study.
Published in:
Cells (2073-4409), 2021, v. 10, n. 2, p. 394, doi. 10.3390/cells10020394
By:
- Seyed Khoei, Nazlisadat;
- Carreras-Torres, Robert;
- Murphy, Neil;
- Gunter, Marc J.;
- Brennan, Paul;
- Smith-Byrne, Karl;
- Mariosa, Daniela;
- Mckay, James;
- O'Mara, Tracy A.;
- Jarrett, Ruth;
- Hjalgrim, Henrik;
- Smedby, Karin E.;
- Cozen, Wendy;
- Onel, Kenan;
- Diepstra, Arjan;
- Wagner, Karl-Heinz;
- Freisling, Heinz;
- Schnütgen, Frank
Publication type:
Article
Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis.
Published in:
International Journal of Epidemiology, 2023, v. 52, n. 1, p. 71, doi. 10.1093/ije/dyac124
By:
- Watts, Eleanor L;
- Perez-Cornago, Aurora;
- Fensom, Georgina K;
- Smith-Byrne, Karl;
- Noor, Urwah;
- Andrews, Colm D;
- Gunter, Marc J;
- Holmes, Michael V;
- Martin, Richard M;
- Tsilidis, Konstantinos K;
- Albanes, Demetrius;
- Barricarte, Aurelio;
- Bueno-de-Mesquita, H Bas;
- Cohn, Barbara A;
- Deschasaux-Tanguy, Melanie;
- Dimou, Niki L;
- Ferrucci, Luigi;
- Flicker, Leon;
- Freedman, Neal D;
- Giles, Graham G
Publication type:
Article
The relationship between blood pressure and risk of renal cell carcinoma.
Published in:
2022
By:
- Alcala, Karine;
- Mariosa, Daniela;
- Smith-Byrne, Karl;
- Nesheli, Dariush Nasrollahzadeh;
- Carreras-Torres, Robert;
- Aicua, Eva Ardanaz;
- Bondonno, Nicola P;
- Bonet, Catalina;
- Brunström, Mattias;
- Bueno-de-Mesquita, Bas;
- Chirlaque, María-Dolores;
- Christakoudi, Sofia;
- Heath, Alicia K;
- Kaaks, Rudolf;
- Katzke, Verena;
- Krogh, Vittorio;
- Ljungberg, Börje;
- Martin, Richard M;
- May, Anne;
- Melander, Olle
Publication type:
journal article
Response to: One size does not fit all-application of accelerometer thresholds in chronic disease.
Published in:
2019
By:
- Barker, Joseph;
- Byrne, Karl Smith;
- Doherty, Aiden;
- Foster, Charlie;
- Rahimi, Kazem;
- Ramakrishnan, Rema;
- Woodward, Mark;
- Dwyer, Terence;
- Smith Byrne, Karl
Publication type:
Letter
Physical activity of UK adults with chronic disease: cross sectional analysis of accelerometer measured physical activity in 96 706 UK Biobank participants.
Published in:
2019
By:
- Barker, Joseph;
- Byrne, Karl Smith;
- Doherty, Aiden;
- Foster, Charlie;
- Rahimi, Kazem;
- Ramakrishnan, Rema;
- Woodward, Mark;
- Dwyer, Terence;
- Smith Byrne, Karl
Publication type:
journal article
Physical activity of UK adults with chronic disease: cross-sectional analysis of accelerometer-measured physical activity in 96 706 UK Biobank participants.
Published in:
2019
By:
- Barker, Joseph;
- Byrne, Karl Smith;
- Doherty, Aiden;
- Foster, Charlie;
- Rahimi, Kazem;
- Ramakrishnan, Rema;
- Woodward, Mark;
- Dwyer, Terence;
- Smith Byrne, Karl
Publication type:
journal article
Smoking and alcohol by HPV status in head and neck cancer: a Mendelian randomization study.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51679-x
By:
- Thakral, Abhinav;
- Lee, John JW.;
- Hou, Tianzhichao;
- Hueniken, Katrina;
- Dudding, Tom;
- Gormley, Mark;
- Virani, Shama;
- Olshan, Andrew;
- Diergaarde, Brenda;
- Ness, Andrew R.;
- Waterboer, Tim;
- Smith-Byrne, Karl;
- Brennan, Paul;
- Hayes, D. Neil;
- Sanderson, Eleanor;
- Brown, M. Catherine;
- Huang, Sophie;
- Bratman, Scott V.;
- Spreafico, Anna;
- De Almeida, John
Publication type:
Article
Smoking and alcohol by HPV status in head and neck cancer: a Mendelian randomization study.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51679-x
By:
- Thakral, Abhinav;
- Lee, John JW.;
- Hou, Tianzhichao;
- Hueniken, Katrina;
- Dudding, Tom;
- Gormley, Mark;
- Virani, Shama;
- Olshan, Andrew;
- Diergaarde, Brenda;
- Ness, Andrew R.;
- Waterboer, Tim;
- Smith-Byrne, Karl;
- Brennan, Paul;
- Hayes, D. Neil;
- Sanderson, Eleanor;
- Brown, M. Catherine;
- Huang, Sophie;
- Bratman, Scott V.;
- Spreafico, Anna;
- De Almeida, John
Publication type:
Article
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46834-3
By:
- Smith-Byrne, Karl;
- Hedman, Åsa;
- Dimitriou, Marios;
- Desai, Trishna;
- Sokolov, Alexandr V.;
- Schioth, Helgi B.;
- Koprulu, Mine;
- Pietzner, Maik;
- Langenberg, Claudia;
- Atkins, Joshua;
- Penha, Ricardo Cortez;
- McKay, James;
- Brennan, Paul;
- Sirui Zhou;
- Richards, Brent J.;
- Yarmolinsky, James;
- Martin, Richard M.;
- Borlido, Joana;
- Mu, Xinmeng J.;
- Butterworth, Adam
Publication type:
Article
Alcohol intake and endogenous sex hormones in women: Meta‐analysis of cohort studies and Mendelian randomization.
Published in:
Cancer (0008543X), 2024, v. 130, n. 19, p. 3375, doi. 10.1002/cncr.35391
By:
- Tin Tin, Sandar;
- Smith‐Byrne, Karl;
- Ferrari, Pietro;
- Rinaldi, Sabina;
- McCullough, Marjorie L.;
- Teras, Lauren R.;
- Manjer, Jonas;
- Giles, Graham;
- Le Marchand, Loïc;
- Haiman, Christopher A.;
- Wilkens, Lynne R.;
- Chen, Yu;
- Hankinson, Sue;
- Tworoger, Shelley;
- Eliassen, A. Heather;
- Willett, Walter C.;
- Ziegler, Regina G.;
- Fuhrman, Barbara J.;
- Sieri, Sabina;
- Agnoli, Claudia
Publication type:
Article
RE: Exploring the cross-cancer effect of circulating proteins and discovering potential intervention targets for 13 site-specific cancers.
Published in:
JNCI: Journal of the National Cancer Institute, 2024, v. 116, n. 5, p. 764, doi. 10.1093/jnci/djae064
By:
- Yarmolinsky, James;
- Tzoulaki, Ioanna;
- Gunter, Marc J;
- Travis, Ruth C;
- Smith, George Davey;
- Smith-Byrne, Karl
Publication type:
Article
Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools.
Published in:
JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 9, p. 1050, doi. 10.1093/jnci/djad071
By:
- Feng, Xiaoshuang;
- Wu, Wendy Yi-Ying;
- Onwuka, Justina Ucheojor;
- Haider, Zahra;
- Alcala, Karine;
- Smith-Byrne, Karl;
- Zahed, Hana;
- Guida, Florence;
- Wang, Renwei;
- Bassett, Julie K;
- Stevens, Victoria;
- Wang, Ying;
- Weinstein, Stephanie;
- Freedman, Neal D;
- Chen, Chu;
- Tinker, Lesley;
- Nøst, Therese Haugdahl;
- Koh, Woon-Puay;
- Muller, David;
- Colorado-Yohar, Sandra M
Publication type:
Article
Body Size at Different Ages and Risk of 6 Cancers: A Mendelian Randomization and Prospective Cohort Study.
Published in:
2022
By:
- Mariosa, Daniela;
- Smith-Byrne, Karl;
- Richardson, Tom G;
- Ferrari, Pietro;
- Gunter, Marc J;
- Papadimitriou, Nikos;
- Murphy, Neil;
- Christakoudi, Sofia;
- Tsilidis, Konstantinos K;
- Riboli, Elio;
- Muller, David;
- Purdue, Mark P;
- Chanock, Stephen J;
- Hung, Rayjean J;
- Amos, Christopher I;
- O'Mara, Tracy A;
- Amiano, Pilar;
- Pasanisi, Fabrizio;
- Rodriguez-Barranco, Miguel;
- Krogh, Vittorio
Publication type:
journal article
Genetic Analysis of Lung Cancer and the Germline Impact on Somatic Mutation Burden.
Published in:
2022
By:
- Gabriel, Aurélie A G;
- Atkins, Joshua R;
- Penha, Ricardo C C;
- Smith-Byrne, Karl;
- Gaborieau, Valerie;
- Voegele, Catherine;
- Abedi-Ardekani, Behnoush;
- Milojevic, Maja;
- Olaso, Robert;
- Meyer, Vincent;
- Boland, Anne;
- Deleuze, Jean François;
- Zaridze, David;
- Mukeriya, Anush;
- Swiatkowska, Beata;
- Janout, Vladimir;
- Schejbalová, Miriam;
- Mates, Dana;
- Stojšić, Jelena;
- Ognjanovic, Miodrag
Publication type:
journal article
FROM SINGLE GENE TO PHENOTYPE: QUESTIONING A DISCRETE GENE IN EXPLAINING PHENOTYPE DIVERSITY.
Published in:
REiDoCrea: Revista Electrónica de Investigación y Docencia Creativa, 2014, v. 3, p. 97
By:
- Smith Byrne, Karl
Publication type:
Article
Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk prediction.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19600-4
By:
- Kachuri, Linda;
- Graff, Rebecca E.;
- Smith-Byrne, Karl;
- Meyers, Travis J.;
- Rashkin, Sara R.;
- Ziv, Elad;
- Witte, John S.;
- Johansson, Mattias
Publication type:
Article

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