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Polyclonal BRCA2 mutations following carboplatin treatment confer resistance to the PARP inhibitor rucaparib in a patient with mCRPC: a case report.
Published in:
2020
By:
- Simmons, Andrew D.;
- Nguyen, Minh;
- Pintus, Elias
Publication type:
journal article
Cell-Free DNA Next-Generation Sequencing Prediction of Response and Resistance to Third-Generation EGFR Inhibitor.
Published in:
2018
By:
- Helman, Elena;
- Nguyen, Minh;
- Karlovich, Chris A.;
- Despain, Darrin;
- Choquette, A. Karin;
- Spira, Alexander I.;
- Yu, Helena A.;
- Camidge, D. Ross;
- Harding, Thomas C.;
- Lanman, Richard B.;
- Simmons, Andrew D.
Publication type:
journal article
Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity.
Published in:
Cancer Immunology, Immunotherapy, 2008, v. 57, n. 8, p. 1263, doi. 10.1007/s00262-008-0451-3
By:
- Simmons, Andrew D.;
- Moskalenko, Marina;
- Creson, Jennifer;
- Jianmin Fang;
- Yi, Saili;
- VanRoey, Melinda J.;
- Allison, James P.;
- Jooss, Karin
Publication type:
Article
GM-CSF-secreting cancer immunotherapies: preclinical analysis of the mechanism of action.
Published in:
Cancer Immunology, Immunotherapy, 2007, v. 56, n. 10, p. 1653, doi. 10.1007/s00262-007-0315-2
By:
- Simmons, Andrew D.;
- Li, Betty;
- Gonzalez-Edick, Melissa;
- Lin, Carol;
- Moskalenko, Marina;
- Du, Thomas;
- Creson, Jennifer;
- VanRoey, Melinda J.;
- Jooss, Karin
Publication type:
Article
Corrigendum: Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.
Published in:
Nature Communications, 2016, v. 7, n. 11, p. 13513, doi. 10.1038/ncomms13513
By:
- Chabon, Jacob J.;
- Simmons, Andrew D.;
- Lovejoy, Alexander F.;
- Esfahani, Mohammad S.;
- Newman, Aaron M.;
- Haringsma, Henry J.;
- Kurtz, David M.;
- Stehr, Henning;
- Scherer, Florian;
- Karlovich, Chris A.;
- Harding, Thomas C.;
- Durkin, Kathleen A.;
- Otterson, Gregory A.;
- Thomas Purcell, W.;
- Ross Camidge, D.;
- Goldman, Jonathan W.;
- Sequist, Lecia V.;
- Piotrowska, Zofia;
- Wakelee, Heather A.;
- Neal, Joel W.
Publication type:
Article
Circulating tumour DNA profiling reveals heterogeneity of EGFR inhibitor resistance mechanisms in lung cancer patients.
Published in:
Nature Communications, 2016, v. 7, n. 6, p. 11815, doi. 10.1038/ncomms11815
By:
- Chabon, Jacob J.;
- Simmons, Andrew D.;
- Lovejoy, Alexander F.;
- Esfahani, Mohammad S.;
- Newman, Aaron M.;
- Haringsma, Henry J.;
- Kurtz, David M.;
- Stehr, Henning;
- Scherer, Florian;
- Karlovich, Chris A.;
- Harding, Thomas C.;
- Durkin, Kathleen A.;
- Otterson, Gregory A.;
- Purcell, W. Thomas;
- Camidge, D. Ross;
- Goldman, Jonathan W.;
- Sequist, Lecia V.;
- Piotrowska, Zofia;
- Wakelee, Heather A.;
- Neal, Joel W.
Publication type:
Article
Population pharmacokinetics of rucaparib in patients with advanced ovarian cancer or other solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2022, v. 89, n. 5, p. 671, doi. 10.1007/s00280-022-04413-7
By:
- Green, Michelle L.;
- Ma, Shu Chin;
- Goble, Sandra;
- Giordano, Heidi;
- Maloney, Lara;
- Simmons, Andrew D.;
- Beltman, Jeri;
- Harding, Thomas C.;
- Xiao, Jim J.
Publication type:
Article
Efficient Tet-Dependent Expression of Human Factor IX in Vivo by a New Self-Regulating Lentiviral Vector
Published in:
Molecular Therapy, 2005, v. 11, n. 5, p. 763, doi. 10.1016/j.ymthe.2004.11.017
By:
- Vigna, Elisa;
- Amendola, Mario;
- Benedicenti, Fabrizio;
- Simmons, Andrew D.;
- Follenzi, Antonia;
- Naldini, Luigi
Publication type:
Article
Clinical Pharmacokinetics and Pharmacodynamics of Rucaparib.
Published in:
Clinical Pharmacokinetics, 2022, v. 61, n. 11, p. 1477, doi. 10.1007/s40262-022-01157-8
By:
- Liao, Mingxiang;
- Beltman, Jeri;
- Giordano, Heidi;
- Harding, Thomas C.;
- Maloney, Lara;
- Simmons, Andrew D.;
- Xiao, Jim J.
Publication type:
Article
A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses.
Published in:
Human Molecular Genetics, 1999, v. 8, n. 12, p. 2155, doi. 10.1093/hmg/8.12.2155
By:
- Simmons, Andrew D.;
- Musy, Maurice M.;
- Lopes, Carla S.;
- Hwang, Larn-Yuan;
- Yang, Ya-Ping;
- Lovett, Michael
Publication type:
Article
Fibroblast activation protein targeted radiotherapy induces an immunogenic tumor microenvironment and enhances the efficacy of PD-1 immune checkpoint inhibition.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2023, v. 50, n. 9, p. 2621, doi. 10.1007/s00259-023-06211-6
By:
- Zboralski, Dirk;
- Osterkamp, Frank;
- Christensen, Esben;
- Bredenbeck, Anne;
- Schumann, Anne;
- Hoehne, Aileen;
- Schneider, Eberhard;
- Paschke, Matthias;
- Ungewiss, Jan;
- Haase, Christian;
- Robillard, Liliane;
- Simmons, Andrew D.;
- Harding, Thomas C.;
- Nguyen, Minh
Publication type:
Article
Preclinical evaluation of FAP-2286 for fibroblast activation protein targeted radionuclide imaging and therapy.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 11, p. 3651, doi. 10.1007/s00259-022-05842-5
By:
- Zboralski, Dirk;
- Hoehne, Aileen;
- Bredenbeck, Anne;
- Schumann, Anne;
- Nguyen, Minh;
- Schneider, Eberhard;
- Ungewiss, Jan;
- Paschke, Matthias;
- Haase, Christian;
- von Hacht, Jan L.;
- Kwan, Tanya;
- Lin, Kevin K.;
- Lenore, Jan;
- Harding, Thomas C.;
- Xiao, Jim;
- Simmons, Andrew D.;
- Mohan, Ajay-Mohan;
- Beindorff, Nicola;
- Reineke, Ulrich;
- Smerling, Christiane
Publication type:
Article
Five novel genes from the cri-du-chat critical region isolated by direct selection.
Published in:
Human Molecular Genetics, 1995, v. 4, n. 2, p. 295
By:
- Simmons, Andrew D.;
- Goodart, Sheryl A.;
- Gallardo, Teresa D.;
- Overhauser, Joan;
- Lovett, Michael
Publication type:
Article

Found: 13