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Untangling the clinicopathological significance of MRE11-RAD50-NBS1 complex in sporadic breast cancers.
Published in:
NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00350-5
By:
- Alblihy, Adel;
- Shoqafi, Ahmed;
- Toss, Michael S.;
- Algethami, Mashael;
- Harris, Anna E.;
- Jeyapalan, Jennie N.;
- Abdel-Fatah, Tarek;
- Servante, Juliette;
- Chan, Stephen Y. T.;
- Green, Andrew;
- Mongan, Nigel P.;
- Rakha, Emad A.;
- Madhusudan, Srinivasan
Publication type:
Article
Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers.
Published in:
NPJ Precision Oncology, 2022, v. 6, n. 1, p. 1, doi. 10.1038/s41698-022-00298-0
By:
- Alblihy, Adel;
- Ali, Reem;
- Algethami, Mashael;
- Shoqafi, Ahmed;
- Toss, Michael S.;
- Brownlie, Juliette;
- Tatum, Natalie J.;
- Hickson, Ian;
- Moran, Paloma Ordonez;
- Grabowska, Anna;
- Jeyapalan, Jennie N.;
- Mongan, Nigel P.;
- Rakha, Emad A.;
- Madhusudan, Srinivasan
Publication type:
Article
Unravelling the clinicopathological and functional significance of replication protein A (RPA) heterotrimeric complex in breast cancers.
Published in:
NPJ Breast Cancer, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41523-023-00524-3
By:
- Algethami, Mashael;
- Toss, Michael S.;
- Woodcock, Corinne L.;
- Jaipal, Chandar;
- Brownlie, Juliette;
- Shoqafi, Ahmed;
- Alblihy, Adel;
- Mesquita, Katia A.;
- Green, Andrew R.;
- Mongan, Nigel P.;
- Jeyapalan, Jennie N.;
- Rakha, Emad A.;
- Madhusudan, Srinivasan
Publication type:
Article
High Expression of RECQL Protein in ER-Positive Breast Tumours Is Associated With a Better Survival.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.877617
By:
- Mahmoodi, Ardalan;
- Shoqafi, Ahmed;
- Sun, Ping;
- Giannakeas, Vasily;
- Cybulski, Cezary;
- Nofech-Mozes, Sharon;
- Masson, Jean-Yves;
- Sharma, Sudha;
- Samani, Amir Abbas;
- Madhusudan, Srinivasan;
- Narod, Steven A.;
- Akbari, Mohammad R.
Publication type:
Article
Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers.
Published in:
Theranostics, 2021, v. 11, n. 17, p. 8350, doi. 10.7150/thno.51456
By:
- Ali, Reem;
- Alabdullah, Muslim;
- Algethami, Mashael;
- Alblihy, Adel;
- Miligy, Islam;
- Shoqafi, Ahmed;
- Mesquita, Katia A.;
- Abdel-Fatah, Tarek;
- Chan, Stephen Y. T.;
- Pei Wen Chiang;
- Mongan, Nigel P.;
- Rakha, Emad A.;
- Tomkinson, Alan E.;
- Madhusudan, Srinivasan
Publication type:
Article
Clinicopathological Significance of Cyclin-Dependent Kinase 2 (CDK2) in Ductal Carcinoma In Situ and Early-Stage Invasive Breast Cancers.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 9, p. 5053, doi. 10.3390/ijms25095053
By:
- Lashen, Ayat;
- Alqahtani, Shatha;
- Shoqafi, Ahmed;
- Algethami, Mashael;
- Jeyapalan, Jennie N.;
- Mongan, Nigel P.;
- Rakha, Emad A.;
- Madhusudan, Srinivasan
Publication type:
Article
The Clinicopathological Significance of the Cyclin D1/E1–Cyclin-Dependent Kinase (CDK2/4/6)–Retinoblastoma (RB1/pRB1) Pathway in Epithelial Ovarian Cancers.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 4060, doi. 10.3390/ijms25074060
By:
- Lashen, Ayat;
- Algethami, Mashael;
- Alqahtani, Shatha;
- Shoqafi, Ahmed;
- Sheha, Amera;
- Jeyapalan, Jennie N.;
- Mongan, Nigel P.;
- Rakha, Emad A.;
- Madhusudan, Srinivasan
Publication type:
Article
Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10966, doi. 10.3390/ijms241310966
By:
- Alblihy, Adel;
- Ali, Reem;
- Algethami, Mashael;
- Ritchie, Alison A.;
- Shoqafi, Ahmed;
- Alqahtani, Shatha;
- Mesquita, Katia A.;
- Toss, Michael S.;
- Ordóñez-Morán, Paloma;
- Jeyapalan, Jennie N.;
- Dekker, Lodewijk;
- Salerno, Martina;
- Hartsuiker, Edgar;
- Grabowska, Anna M.;
- Rakha, Emad A.;
- Mongan, Nigel P.;
- Madhusudan, Srinivasan
Publication type:
Article

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