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Stability analysis of a model gene network links aging, stress resistance, and negligible senescence.
- Published in:
- Scientific Reports, 2015, p. 13589, doi. 10.1038/srep13589
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- Publication type:
- Article
Telomerase inhibition by peptide nucleic acids reverses `immortality' of transformed human cells.
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- Oncogene, 1999, v. 18, n. 46, p. 6191, doi. 10.1038/sj.onc.1203069
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- Publication type:
- Article
Design and Synthesis of Novel Hybrid 8-Hydroxy Quinoline-Indole Derivatives as Inhibitors of Aβ Self-Aggregation and Metal Chelation-Induced Aβ Aggregation.
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- Molecules, 2020, v. 25, n. 16, p. 3610, doi. 10.3390/molecules25163610
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- Article
A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43075-z
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- Publication type:
- Article
Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33143-1
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- Publication type:
- Article
ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31199-7
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- Publication type:
- Article
Interspecies synteny mapping identifies a quantitative trait locus for bone mineral density on human chromosome Xp22.
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- Human Molecular Genetics, 2005, v. 14, n. 21, p. 3141, doi. 10.1093/hmg/ddi346
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- Article
A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer's Disease.
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- Frontiers in Molecular Neuroscience, 2019, v. 12, p. 1, doi. 10.3389/fnmol.2019.00310
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- Article
Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15457, doi. 10.3390/ijms232415457
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- Article
Histoplasma capsulatum and Caenorhabditis elegans: a simple nematode model for an innate immune response to fungal infection.
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- Medical Mycology, 2009, v. 47, n. 8, p. 808, doi. 10.3109/13693780802660532
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- Publication type:
- Article
Rec-8 dimorphism affects longevity, stress resistance and X-chromosome nondisjunction in C. elegans, and replicative lifespan in S. cerevisiae.
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- Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00211
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- Publication type:
- Article
Rec-8 dimorphism affects longevity, stress resistance and X-chromosome nondisjunction in C. elegans, and replicative lifespan in S. cerevisiae.
- Published in:
- Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00211
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- Publication type:
- Article
Positive Feedback between Transcriptional and Kinase Suppression in Nematodes with Extraordinary Longevity and Stress Resistance.
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- PLoS Genetics, 2009, v. 5, n. 4, p. 1, doi. 10.1371/journal.pgen.1000452
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- Article
Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, n. 2, p. 230, doi. 10.1016/j.jalz.2017.07.754
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- Publication type:
- Article
An iterative block-shifting approach to retention time alignment that preserves the shape and area of gas chromatography-mass spectrometry peaks.
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- BMC Bioinformatics, 2008, v. 9, p. 1, doi. 10.1186/1471-2105-9-S9-S15
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- Publication type:
- Article
Gene Categories Differentially Expressed in C. elegans Age-1 Mutants of Extraordinary Longevity: New Insights From Novel Data-Mining Procedures.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67A, n. 4, p. 366, doi. 10.1093/gerona/glr186
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- Article
Interpretation, design, and analysis of gene array expression experiments.
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- 2001
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- Publication type:
- journal article
Cellular and Molecular Biomarkers Indicate Precocious in vitro Senescence in Fibroblasts From...
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 1997, v. 52A, n. 6, p. B331
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- Publication type:
- Article
Photoacoustically-guided photothermal killing of mosquitoes targeted by nanoparticles.
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- Journal of Biophotonics, 2014, v. 7, n. 7, p. 465, doi. 10.1002/jbio.201200199
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- Article
From QTL Mapping to Genes: The Long and Winding Road.
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- Journal of Bone & Mineral Research, 2003, v. 18, n. 2, p. 186, doi. 10.1359/jbmr.2003.18.2.186
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- Article
Chromosomal Mapping of Osteopenia-Associated Quantitative Trait Loci Using Closely Related Mouse Strains.
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- Journal of Bone & Mineral Research, 2000, v. 15, n. 4, p. 626, doi. 10.1359/jbmr.2000.15.4.626
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- Publication type:
- Article
Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation.
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- Frontiers in Aging Neuroscience, 2022, v. 14, p. 01, doi. 10.3389/fnagi.2022.938117
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- Publication type:
- Article
Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-98661-x
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- Publication type:
- Article
Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75020-w
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- Publication type:
- Article
In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration.
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- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28381-x
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- Publication type:
- Article
Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration.
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- Metabolic Brain Disease, 2022, v. 37, n. 1, p. 147, doi. 10.1007/s11011-021-00791-8
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- Article
Cross-talk between LOX-1 and PCSK9 in vascular tissues.
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- Cardiovascular Research, 2015, v. 107, n. 4, p. 556, doi. 10.1093/cvr/cvv178
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- Publication type:
- Article
Animal models for discovery and assessment of genetic determinants of osteoporosis.
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- Osteoporosis International, 2003, v. 14, p. 100, doi. 10.1007/s00198-003-1480-6
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- Publication type:
- Article
Interaction of Adeno-Associated Virus Rep78 with SV40 T Antigen: Implications in Rep Protein Expression Leading to the Inhibition of SV40-Mediated Cell Proliferation.
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- Intervirology, 2002, v. 45, n. 2, p. 115, doi. 10.1159/000063235
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- Article
Expression of AAV Rep Proteins in SV40-Transformed and Untransformed Cells: Reciprocal Interaction with Host DNA Synthesis.
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- Intervirology, 2001, v. 44, n. 5, p. 298, doi. 10.1159/000050061
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- Publication type:
- Article
Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer's disease by targeted small molecules.
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- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-05767-9
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- Publication type:
- Article
"Protein aggregates" contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation.
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- Aging Cell, 2021, v. 20, n. 5, p. 1, doi. 10.1111/acel.13326
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- Article
Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls.
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- Aging Cell, 2016, v. 15, n. 5, p. 924, doi. 10.1111/acel.12501
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- Publication type:
- Article
Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan.
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- Aging Cell, 2009, v. 8, n. 6, p. 706, doi. 10.1111/j.1474-9726.2009.00524.x
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- Publication type:
- Article
Remarkable longevity and stress resistance of nematode PI3K-null mutants.
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- Aging Cell, 2008, v. 7, n. 1, p. 13, doi. 10.1111/j.1474-9726.2007.00348.x
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- Publication type:
- Article
Lifespan extension in hypomorphic daf-2 mutants of Caenorhabditis elegans is partially mediated by glutathione transferase CeGSTP2-2.
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- Aging Cell, 2005, v. 4, n. 6, p. 299, doi. 10.1111/j.1474-9726.2005.00172.x
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- Publication type:
- Article
Lifespan and stress resistance of Caenorhabditis elegans are increased by expression of glutathione transferases capable of metabolizing the lipid peroxidation product 4-hydroxynonenal.
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- Aging Cell, 2005, v. 4, n. 5, p. 257, doi. 10.1111/j.1474-9726.2005.00168.x
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- Publication type:
- Article
Genetic Loci Modulating Fitness and Life Span in Caenorhabditis elegans: Categorical Trait Interval Mapping in CL2a x Bergerac-BO Recombinant-Inbred Worms.
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- Genetics, 2003, v. 163, n. 2, p. 557, doi. 10.1093/genetics/163.2.557
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- Article
Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer's Disease.
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- Pharmaceutics, 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/pharmaceutics14071354
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- Publication type:
- Article
Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 10, p. 1498, doi. 10.3390/ph16101498
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- Publication type:
- Article