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Improvement of the affinity of an anti-rat P2X4 receptor antibody by introducing electrostatic interactions.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-03784-w
By:
- Shinozaki, Chinatsu;
- Kohno, Keita;
- Shiroishi, Mitsunori;
- Takahashi, Daisuke;
- Yoshikawa, Yu;
- Abe, Yoshito;
- Hamase, Kenji;
- Nakakido, Makoto;
- Tsumoto, Kohei;
- Inoue, Kazuhide;
- Tsuda, Makoto;
- Ueda, Tadashi
Publication type:
Article
Binding characteristics of the doxepin E/Z‐isomers to the histamine H1 receptor revealed by receptor‐bound ligand analysis and molecular dynamics study.
Published in:
Journal of Molecular Recognition, 2024, v. 37, n. 5, p. 1, doi. 10.1002/jmr.3098
By:
- Kaneko, Hiroto;
- Korenaga, Ryunosuke;
- Nakamura, Ryota;
- Kawai, Shinnosuke;
- Ando, Tadashi;
- Shiroishi, Mitsunori
Publication type:
Article
Structure of the human histamine H1 receptor complex with doxepin.
Published in:
Nature, 2011, v. 475, n. 7354, p. 65, doi. 10.1038/nature10236
By:
- Shimamura, Tatsuro;
- Shiroishi, Mitsunori;
- Weyand, Simone;
- Tsujimoto, Hirokazu;
- Winter, Graeme;
- Katritch, Vsevolod;
- Abagyan, Ruben;
- Cherezov, Vadim;
- Wei Liu;
- Han, Gye Won;
- Kobayashi, Takuya;
- Stevens, Raymond C.;
- Iwata, So
Publication type:
Article
Production and characterization of an Fv-clasp of rheumatoid factor, a low-affinity human autoantibody.
Published in:
Journal of Biochemistry, 2024, v. 175, n. 4, p. 387, doi. 10.1093/jb/mvad112
By:
- Yamamoto, Maruto;
- Funada, Ryoma;
- Taki, Ryota;
- Shiroishi, Mitsunori
Publication type:
Article
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.
Published in:
Nature, 2012, v. 482, n. 7386, p. 547, doi. 10.1038/nature10753
By:
- Haga, Kazuko;
- Kruse, Andrew C.;
- Asada, Hidetsugu;
- Yurugi-Kobayashi, Takami;
- Shiroishi, Mitsunori;
- Zhang, Cheng;
- Weis, William I.;
- Okada, Tetsuji;
- Kobilka, Brian K.;
- Haga, Tatsuya;
- Kobayashi, Takuya
Publication type:
Article
Genome destabilization-associated phenotypes arising as a consequence of therapeutic treatment are suppressed by Olaparib.
Published in:
PLoS ONE, 2023, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0281168
By:
- Suzuki, Mafuka;
- Fujimori, Haruka;
- Wakatsuki, Kakeru;
- Manaka, Yuya;
- Asai, Haruka;
- Hyodo, Mai;
- Matsuno, Yusuke;
- Kusumoto-Matsuo, Rika;
- Shiroishi, Mitsunori;
- Yoshioka, Ken-ichi
Publication type:
Article
The powerful potential of amino acid menthyl esters for anti‐inflammatory and anti‐obesity therapies.
Published in:
Immunology, 2024, v. 173, n. 1, p. 76, doi. 10.1111/imm.13798
By:
- Takasawa, Seidai;
- Kimura, Kosuke;
- Miyanaga, Masato;
- Uemura, Takuya;
- Hachisu, Masakazu;
- Miyagawa, Shinichi;
- Ramadan, Abdelaziz;
- Sukegawa, Satoru;
- Kobayashi, Masaki;
- Kimura, Seisuke;
- Matsui, Kenji;
- Shiroishi, Mitsunori;
- Terashita, Kaori;
- Nishiyama, Chiharu;
- Yashiro, Takuya;
- Nagata, Kazuki;
- Higami, Yoshikazu;
- Arimura, Gen‐ichiro
Publication type:
Article
Cysteine-to-serine shuffling using a Saccharomyces cerevisiae expression system improves protein secretion: case of a nonglycosylated mutant of miraculin, a taste-modifying protein.
Published in:
Biotechnology Letters, 2011, v. 33, n. 1, p. 103, doi. 10.1007/s10529-010-0399-1
By:
- Ito, Keisuke;
- Sugawara, Taishi;
- Koizumi, Ayako;
- Nakajima, Ken-ichiro;
- Shimizu-Ibuka, Akiko;
- Shiroishi, Mitsunori;
- Asada, Hidetsugu;
- Yurugi-Kobayashi, Takami;
- Shimamura, Tatsuro;
- Asakura, Tomiko;
- Misaka, Takumi;
- Iwata, So;
- Kobayashi, Takuya;
- Abe, Keiko
Publication type:
Article
Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis.
Published in:
Human Molecular Genetics, 2005, v. 14, n. 16, p. 2469, doi. 10.1093/hmg/ddi247
By:
- Kuroki, Kimiko;
- Tsuchiya, Naoyuki;
- Shiroishi, Mitsunori;
- Rasubala, Linda;
- Yamashita, Yumi;
- Matsuta, Kunio;
- Fukazawa, Toru;
- Kusaoi, Makio;
- Murakami, Yoshinori;
- Takiguchi, Masafumi;
- Juji, Takeo;
- Hashimoto, Hiroshi;
- Kohda, Daisuke;
- Maenaka, Katsumi;
- Tokunaga, Katsushi
Publication type:
Article
Platform for the rapid construction and evaluation of GPCRs for crystallography in Saccharomyces cerevisiae.
Published in:
Microbial Cell Factories, 2012, v. 11, n. 1, p. 78, doi. 10.1186/1475-2859-11-78
By:
- Shiroishi, Mitsunori;
- Tsujimoto, Hirokazu;
- Makyio, Hisayoshi;
- Asada, Hidetsugu;
- Yurugi-Kobayashi, Takami;
- Shimamura, Tatsuro;
- Murata, Takeshi;
- Nomura, Norimichi;
- Haga, Tatsuya;
- Iwata, So;
- Kobayashi, Takuya
Publication type:
Article
Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis.
Published in:
Microbial Cell Factories, 2011, v. 10, n. 1, p. 24, doi. 10.1186/1475-2859-10-24
By:
- Asada, Hidetsugu;
- Uemura, Tomoko;
- Yurugi-Kobayashi, Takami;
- Shiroishi, Mitsunori;
- Shimamura, Tatsuro;
- Tsujimoto, Hirokazu;
- Ito, Keisuke;
- Sugawara, Taishi;
- Nakane, Takanori;
- Nomura, Norimichi;
- Murata, Takeshi;
- Haga, Tatsuya;
- Iwata, So;
- Kobayashi, Takuya
Publication type:
Article
Recovery of the histamine H3 receptor activity lost in yeast cells through error-prone PCR and in vivo selection.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43389-z
By:
- Watanabe, Ayami;
- Nakajima, Ami;
- Shiroishi, Mitsunori
Publication type:
Article
Recovery of the histamine H3 receptor activity lost in yeast cells through error-prone PCR and in vivo selection.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-43389-z
By:
- Watanabe, Ayami;
- Nakajima, Ami;
- Shiroishi, Mitsunori
Publication type:
Article
Anti-nanodisc antibodies specifically capture nanodiscs and facilitate molecular interaction kinetics studies for membrane protein.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38547-2
By:
- Nakagawa, Fuhito;
- Kikkawa, Marin;
- Chen, Sisi;
- Miyashita, Yasuomi;
- Hamaguchi-Suzuki, Norie;
- Shibuya, Minami;
- Yamashita, Soichi;
- Nagase, Lisa;
- Yasuda, Satoshi;
- Shiroishi, Mitsunori;
- Senda, Toshiya;
- Ito, Keisuke;
- Murata, Takeshi;
- Ogasawara, Satoshi
Publication type:
Article
A methodology for creating mutants of G‐protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering.
Published in:
Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 10, p. 1, doi. 10.1002/pro.4425
By:
- Yamamoto, Taisei;
- Yasuda, Satoshi;
- Kasai, Rinshi S.;
- Nakano, Ryosuke;
- Hikiri, Simon;
- Sugaya, Kanna;
- Hayashi, Tomohiko;
- Ogasawara, Satoshi;
- Shiroishi, Mitsunori;
- Fujiwara, Takahiro K.;
- Kinoshita, Masahiro;
- Murata, Takeshi
Publication type:
Article
Micro-scale and rapid expression screening of highly expressed and/or stable membrane protein variants in Saccharomyces cerevisiae.
Published in:
Protein Science: A Publication of the Protein Society, 2016, v. 25, n. 10, p. 1863, doi. 10.1002/pro.2993
By:
- Shiroishi, Mitsunori;
- Moriya, Mai;
- Ueda, Tadashi
Publication type:
Article

Found: 16

Improvement of the affinity of an anti-rat P2X4 receptor antibody by introducing electrostatic interactions.

Binding characteristics of the doxepin E/Z‐isomers to the histamine H<sub>1</sub> receptor revealed by receptor‐bound ligand analysis and molecular dynamics study.

Structure of the human histamine H<sub>1</sub> receptor complex with doxepin.

Production and characterization of an Fv-clasp of rheumatoid factor, a low-affinity human autoantibody.

Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist.

Genome destabilization-associated phenotypes arising as a consequence of therapeutic treatment are suppressed by Olaparib.

The powerful potential of amino acid menthyl esters for anti‐inflammatory and anti‐obesity therapies.

Cysteine-to-serine shuffling using a Saccharomyces cerevisiae expression system improves protein secretion: case of a nonglycosylated mutant of miraculin, a taste-modifying protein.

Extensive polymorphisms of LILRB1 (ILT2, LIR1) and their association with HLA-DRB1 shared epitope negative rheumatoid arthritis.

Platform for the rapid construction and evaluation of GPCRs for crystallography in Saccharomyces cerevisiae.

Evaluation of the Pichia pastoris expression system for the production of GPCRs for structural analysis.

Recovery of the histamine H<sub>3</sub> receptor activity lost in yeast cells through error-prone PCR and in vivo selection.

Recovery of the histamine H<sub>3</sub> receptor activity lost in yeast cells through error-prone PCR and in vivo selection.

Anti-nanodisc antibodies specifically capture nanodiscs and facilitate molecular interaction kinetics studies for membrane protein.

A methodology for creating mutants of G‐protein coupled receptors stabilized in active state by combining statistical thermodynamics and evolutionary molecular engineering.

Micro-scale and rapid expression screening of highly expressed and/or stable membrane protein variants in Saccharomyces cerevisiae.