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Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in C9orf72 ALS/FTD models.
- Published in:
- Life Science Alliance, 2024, v. 7, n. 9, p. 1, doi. 10.26508/lsa.202402853
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- Publication type:
- Article
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
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- Life Science Alliance, 2023, v. 6, n. 1, p. 1, doi. 10.26508/lsa.202201449
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- Publication type:
- Article
Oligogenic inheritance of optineurin ( OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS.
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- Neuropathology, 2016, v. 36, n. 2, p. 125, doi. 10.1111/neup.12240
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- Publication type:
- Article
Micro-RNAs Shuttled by Extracellular Vesicles Secreted from Mesenchymal Stem Cells Dampen Astrocyte Pathological Activation and Support Neuroprotection in In-Vitro Models of ALS.
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- Cells (2073-4409), 2022, v. 11, n. 23, p. 3923, doi. 10.3390/cells11233923
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- Publication type:
- Article
Differentiation of human adipose-derived stem cells into neuron/motoneuron-like cells for cell replacement therapy of spinal cord injury.
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- Cell Death & Disease, 2019, v. 10, n. 8, p. N.PAG, doi. 10.1038/s41419-019-1772-1
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- Article
Proteomic Approaches to Study Cysteine Oxidation: Applications in Neurodegenerative Diseases.
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- Frontiers in Molecular Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnmol.2021.678837
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- Article
Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial Activity.
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- Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2017.00731
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- Publication type:
- Article
Microarray Analysis of the Cellular Pathways Involved in the Adaptation to and Progression of Motor Neuron Injury in the SOD1 G93A Mouse Model of Familial ALS.
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- Journal of Neuroscience, 2007, v. 27, n. 34, p. 9201, doi. 10.1523/JNEUROSCI.1470-07.2007
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- Publication type:
- Article
Direct evidence for axonal transport defects in a novel mouse model of mutant spastin-induced hereditary spastic paraplegia (HSP) and human HSP patients.
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- Journal of Neurochemistry, 2009, v. 110, n. 1, p. 34, doi. 10.1111/j.1471-4159.2009.06104.x
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- Article
Transcriptional response of the neuromuscular system to exercise training and potential implications for ALS.
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- Journal of Neurochemistry, 2009, v. 109, n. 6, p. 1714, doi. 10.1111/j.1471-4159.2009.06080.x
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- Publication type:
- Article
Assessment of the Precision in Measuring Glutathione at 3 T With a MEGA‐PRESS Sequence in Primary Motor Cortex and Occipital Cortex.
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- Journal of Magnetic Resonance Imaging, 2022, v. 55, n. 2, p. 435, doi. 10.1002/jmri.27842
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- Publication type:
- Article
PTEN Depletion Decreases Disease Severity and Modestly Prolongs Survival in a Mouse Model of Spinal Muscular Atrophy.
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- Molecular Therapy, 2015, v. 23, n. 2, p. 270, doi. 10.1038/mt.2014.209
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- Publication type:
- Article
ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.
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- Human Molecular Genetics, 2013, v. 22, n. 18, p. 3690, doi. 10.1093/hmg/ddt222
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- Publication type:
- Article
Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish.
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- Human Molecular Genetics, 2013, v. 22, n. 12, p. 2376, doi. 10.1093/hmg/ddt082
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- Publication type:
- Article
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content.
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- Human Molecular Genetics, 2007, v. 16, n. 22, p. 2720, doi. 10.1093/hmg/ddm226
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- Publication type:
- Article
The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo.
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- Human Molecular Genetics, 2006, v. 15, n. 18, p. 2763, doi. 10.1093/hmg/ddl212
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- Publication type:
- Article
Homozygosity analysis in amyotrophic lateral sclerosis.
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- European Journal of Human Genetics, 2013, v. 21, n. 12, p. 1429, doi. 10.1038/ejhg.2013.59
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- Publication type:
- Article
Membrane lipid raft homeostasis is directly linked to neurodegeneration.
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- Essays in Biochemistry, 2021, v. 65, n. 7, p. 999, doi. 10.1042/EBC20210026
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- Article
Physical activity as an exogenous risk factor for amyotrophic lateral sclerosis: a review of the evidence.
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- Brain: A Journal of Neurology, 2023, v. 146, n. 5, p. 1745, doi. 10.1093/brain/awac470
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- Article
A review of Mendelian randomization in amyotrophic lateral sclerosis.
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- 2022
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- Publication type:
- journal article
Magnetic resonance spectroscopy reveals mitochondrial dysfunction in amyotrophic lateral sclerosis.
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- 2020
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- Publication type:
- journal article
Disrupted glycosylation of lipids and proteins is a cause of neurodegeneration.
- Published in:
- 2020
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- Publication type:
- journal article
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.
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- 2019
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- Publication type:
- journal article
Lost in translation: microRNAs mediate pathological cross-talk between motor neurons and astrocytes.
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- 2018
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- Publication type:
- journal article
A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK.
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- 2017
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- Publication type:
- journal article
Early interneuron dysfunction in ALS: Insights from a mutant sod1 zebrafish model.
- Published in:
- Annals of Neurology, 2013, v. 73, n. 2, p. 246, doi. 10.1002/ana.23780
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- Publication type:
- Article
Blood–Brain Barrier Disruption and Its Involvement in Neurodevelopmental and Neurodegenerative Disorders.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15271, doi. 10.3390/ijms232315271
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- Article
The gut microbiome: a key player in the complexity of amyotrophic lateral sclerosis (ALS).
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- 2021
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- Publication type:
- journal article
Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF<sup>delta;/delta;</sup> mouse model of amyotrophic lateral sclerosis.
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- BMC Genomics, 2010, v. 11, p. 203, doi. 10.1186/1471-2164-11-203
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- Publication type:
- Article
Unravelling the enigma of selective vulnerability in neurodegeneration: motor neurons resistant to degeneration in ALS show distinct gene expression characteristics and decreased susceptibility to excitotoxicity.
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- Acta Neuropathologica, 2013, v. 125, n. 1, p. 95, doi. 10.1007/s00401-012-1058-5
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- Publication type:
- Article
Type 2 diabetes mellitus-associated transcriptome alterations in cortical neurones and associated neurovascular unit cells in the ageing brain.
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- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-020-01109-y
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- Article
Advances, challenges and future directions for stem cell therapy in amyotrophic lateral sclerosis.
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- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0227-3
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- Publication type:
- Article
ZNStress: a high-throughput drug screening protocol for identification of compounds modulating neuronal stress in the transgenic mutant sod1G93R zebrafish model of amyotrophic lateral sclerosis.
- Published in:
- Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0122-3
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- Publication type:
- Article
Simultaneous and independent detection of C9ORF72 alleles with low and high number of GGGGCC repeats using an optimised protocol of Southern blot hybridisation.
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- Molecular Neurodegeneration, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1326-8-12
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- Publication type:
- Article
Development and Characterisation of a Glutamate-Sensitive Motor Neurone Cell Line.
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- Journal of Neurochemistry, 2000, v. 74, n. 5, p. 1895, doi. 10.1046/j.1471-4159.2000.0741895.x
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- Publication type:
- Article
Peroxynitrite and Hydrogen Peroxide Induced Cell Death in the NSC34 Neuroblastoma × Spinal Cord Cell Line: Role of Poly(ADP-Ribose) Polymerase.
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- Journal of Neurochemistry, 1998, v. 70, n. 2, p. 501, doi. 10.1046/j.1471-4159.1998.70020501.x
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- Publication type:
- Article
Lysosomal and phagocytic activity is increased in astrocytes during disease progression in the SOD1<sup>G93A</sup> mouse model of amyotrophic lateral sclerosis.
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- Frontiers in Cellular Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fncel.2015.00410
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- Publication type:
- Article
Adaptation to culture of human embryonic stem cells and oncogenesis in vivo.
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- Nature Biotechnology, 2007, v. 25, n. 2, p. 207, doi. 10.1038/nbt1285
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- Publication type:
- Article
P4-119: Characterization of ubiquitin positive inclusions in frontotemporal dementia
- Published in:
- 2006
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- Publication type:
- Abstract
P4-119: Characterization of ubiquitin positive inclusions in frontotemporal dementia
- Published in:
- 2006
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- Publication type:
- Abstract
A randomised controlled trial of acceptance and commitment therapy plus usual care compared to usual care alone for improving psychological health in people with motor neuron disease (COMMEND): study protocol.
- Published in:
- 2022
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- Publication type:
- journal article
Creatine kinase and prognosis in amyotrophic lateral sclerosis: a literature review and multi-centre cohort analysis.
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- Journal of Neurology, 2022, v. 269, n. 10, p. 5395, doi. 10.1007/s00415-022-11195-8
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- Publication type:
- Article
Correction to: Longitudinal multi-modal muscle-based biomarker assessment in motor neuron disease.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Longitudinal multi-modal muscle-based biomarker assessment in motor neuron disease.
- Published in:
- Journal of Neurology, 2020, v. 267, n. 1, p. 244, doi. 10.1007/s00415-019-09580-x
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- Publication type:
- Article
Mutations in the tail and rod domains of the neurofilament heavy‐chain gene increase the risk of ALS.
- Published in:
- Annals of Clinical & Translational Neurology, 2024, v. 11, n. 7, p. 1775, doi. 10.1002/acn3.52083
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- Publication type:
- Article
Early Detection of Motor Dysfunction in the SOD1<sup>G93A</sup> Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Using Home Cage Running Wheels.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0107918
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- Publication type:
- Article
An Evaluation of a SVA Retrotransposon in the <i>FUS</i> Promoter as a Transcriptional Regulator and Its Association to ALS.
- Published in:
- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090833
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- Publication type:
- Article
Comparison of Blood RNA Extraction Methods Used for Gene Expression Profiling in Amyotrophic Lateral Sclerosis.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087508
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- Publication type:
- Article
The Effect of SOD1 Mutation on Cellular Bioenergetic Profile and Viability in Response to Oxidative Stress and Influence of Mutation-Type.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0068256
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- Publication type:
- Article
Optimised and Rapid Pre-clinical Screening in the SOD1<sup>G93A</sup> Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS).
- Published in:
- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023244
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- Publication type:
- Article