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Crizotinib.
Published in:
2011
By:
- Shaw, Alice T.;
- Yasothan, Uma;
- Kirkpatrick, Peter
Publication type:
journal article
KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.18970
By:
- Krall, Elsa B.;
- Wang, Belinda;
- Munoz, Diana M.;
- Ilic, Nina;
- Raghavan, Srivatsan;
- Niederst, Matthew J.;
- Yu, Kristine;
- Ruddy, David A.;
- Aguirre, Andrew J.;
- Kim, Jong Wook;
- Redig, Amanda J.;
- Gainor, Justin F.;
- Williams, Juliet A.;
- Asara, John M.;
- Doench, John G.;
- Janne, Pasi A.;
- Shaw, Alice T.;
- McDonald III, Robert E.;
- Engelman, Jeffrey A.;
- Stegmeier, Frank
Publication type:
Article
Computed Tomography Imaging Features and Distribution of Metastases in ROS1-rearranged Non-Small-cell Lung Cancer.
Published in:
2020
By:
- Digumarthy, Subba R.;
- Mendoza, Dexter P.;
- Lin, Jessica J.;
- Chen, Tianqi;
- Rooney, Marguerite M.;
- Chin, Emily;
- Sequist, Lecia V.;
- Lennerz, Jochen K.;
- Gainor, Justin F.;
- Shaw, Alice T.
Publication type:
journal article
Computed Tomography Imaging Characteristics of Non-Small-Cell Lung Cancer With Anaplastic Lymphoma Kinase Rearrangements: A Systematic Review and Meta-Analysis.
Published in:
2019
By:
- Mendoza, Dexter P.;
- Stowell, Justin;
- Muzikansky, Alona;
- Shepard, Jo-Anne O.;
- Shaw, Alice T.;
- Digumarthy, Subba R.
Publication type:
journal article
Identification of osimertinib-resistant EGFR L792 mutations by cfDNA sequencing: oncogenic activity assessment and prevalence in large cfDNA cohort.
Published in:
Experimental Hematology & Oncology, 2019, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40164-019-0148-7
By:
- Fairclough, Stephen R.;
- Kiedrowski, Lesli A.;
- Lin, Jessica J.;
- Zelichov, Ori;
- Tarcic, Gabi;
- Stinchcombe, Thomas E.;
- Odegaard, Justin I.;
- Lanman, Richard B.;
- Shaw, Alice T.;
- Nagy, Rebecca J.
Publication type:
Article
Time To Response In Patients With Advanced Anaplastic Lymphoma Kinase (ALK)-Positive Non-Small-Cell Lung Cancer (NSCLC) Receiving Alectinib In The Phase II NP28673 And NP28761 Studies.
Published in:
Lung Cancer: Targets & Therapy, 2019, v. 10, p. 125, doi. 10.2147/LCTT.S209231
By:
- Gadgeel, Shirish;
- Shaw, Alice T;
- Barlesi, Fabrice;
- Crino, Lucio;
- Yang, James CH;
- Dingemans, Anne-Marie;
- Kim, Dong-Wan;
- Marinis, Filippo de;
- Schulz, Mathias;
- Liu, Shiyao;
- Gupta, Ravindra;
- Smoljanovic, Vlatka;
- Ou, Sai-Hong Ignatius
Publication type:
Article
Targeted inhibition in tumors with ALK dependency.
Published in:
Lung Cancer: Targets & Therapy, 2013, v. 4, p. 1, doi. 10.2147/LCTT.S16313
By:
- Kwak, Eunice L.;
- Clark, Jeffrey W.;
- Shaw, Alice T.
Publication type:
Article
Crizotinib versus Chemotherapy in Asian Patients with ALK-Positive Advanced Non-small Cell Lung Cancer.
Published in:
Cancer Research & Treatment, 2018, v. 50, n. 3, p. 691, doi. 10.4143/crt.2017.280
By:
- Makoto Nishio;
- Dong-Wan Kim;
- Yi-Long Wu;
- Kazuhiko Nakagawa;
- Solomon, Benjamin J.;
- Shaw, Alice T.;
- Satoshi Hashigaki;
- Emiko Ohki;
- Usari, Tiziana;
- Paolini, Jolanda;
- Polli, Anna;
- Wilner, Keith D.;
- Mok, Tony
Publication type:
Article
Imaging Features and Patterns of Metastasis in Non-Small Cell Lung Cancer with RET Rearrangements.
Published in:
Cancers, 2020, v. 12, n. 3, p. 693, doi. 10.3390/cancers12030693
By:
- Digumarthy, Subba R.;
- Mendoza, Dexter P.;
- Lin, Jessica J.;
- Rooney, Marguerite;
- Do, Andrew;
- Chin, Emily;
- Yeap, Beow Y.;
- Shaw, Alice T.;
- Gainor, Justin F.
Publication type:
Article
Complex renal cysts associated with crizotinib treatment.
Published in:
Cancer Medicine, 2015, v. 4, n. 6, p. 887, doi. 10.1002/cam4.437
By:
- Schnell, Patrick;
- Bartlett, Cynthia H.;
- Solomon, Benjamin J.;
- Tassell, Vanessa;
- Shaw, Alice T.;
- Pas, Tommaso;
- Lee, Soo‐Hyun;
- Lee, Geon Kook;
- Tanaka, Kaoru;
- Tan, Weiwei;
- Tang, Yiyun;
- Wilner, Keith D.;
- Safferman, Allan;
- Han, Ji‐Youn
Publication type:
Article
Significance of targeted therapy and genetic alterations in EGFR, ALK, or KRAS on survival in patients with non–small cell lung cancer treated with radiotherapy for brain metastases.
Published in:
Neuro-Oncology, 2015, v. 17, n. 2, p. 296, doi. 10.1093/neuonc/nou146
By:
- Mak, Kimberley S.;
- Gainor, Justin F.;
- Niemierko, Andrzej;
- Oh, Kevin S.;
- Willers, Henning;
- Choi, Noah C.;
- Loeffler, Jay S.;
- Sequist, Lecia V.;
- Shaw, Alice T.;
- Shih, Helen A.
Publication type:
Article
Alectinib a New Standard of Care for ALK-Positive NSCLC.
Published in:
Journal of Oncology Navigation & Survivorship, 2017, v. 8, n. 8, p. 384
By:
- Shaw, Alice T.
Publication type:
Article
Cumulative incidence rates for CNS and non-CNS progression in two phase II studies of alectinib in ALK-positive NSCLC.
Published in:
2018
By:
- Gadgeel, Shirish;
- Shaw, Alice T;
- Barlesi, Fabrice;
- Crinò, Lucio;
- Yang, James Chih-Hsin;
- Dingemans, Anne-Marie C;
- Kim, Dong-Wan;
- de Marinis, Filippo;
- Schulz, Mathias;
- Liu, Shiyao;
- Gupta, Ravindra;
- Kotb, Ahmed;
- Ou, Sai-Hong Ignatius;
- Crinò, Lucio
Publication type:
journal article
Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers.
Published in:
Science Translational Medicine, 2012, v. 4, n. 120, p. 1, doi. 10.1126/scitranslmed.3003316
By:
- Katayama, Ryohei;
- Shaw, Alice T.;
- Khan, Tahsin M.;
- Mino-Kenudson, Mari;
- Solomon, Benjamin J.;
- Halmos, Balazs;
- Jessop, Nicholas A.;
- Wain, John C.;
- Alan Tien Yeo;
- Benes, Cyril;
- Drew, Lisa;
- Saeh, Jamal Carlos;
- Crosby, Katherine;
- Sequist, Lecia V.;
- Iafrate, A. John;
- Engelman, Jeffrey A.
Publication type:
Article
Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors.
Published in:
Science Translational Medicine, 2011, v. 3, n. 75, p. 1, doi. 10.1126/scitranslmed.3002003
By:
- Sequist, Lecia V.;
- Waltman, Belinda A.;
- Dias-Santagata, Dora;
- Digumarthy, Subba;
- Turke, Alexa B.;
- Fidias, Panos;
- Bergethon, Kristin;
- Shaw, Alice T.;
- Gettinger, Scott;
- Cosper, Arjola K.;
- Akhavanfard, Sara;
- Heist, Rebecca S.;
- Temel, Jennifer;
- Christensen, James G.;
- Wain, John C.;
- Lynch, Thomas J.;
- Vernovsky, Kathy;
- Mark, Eugene J.;
- Lanuti, Michael;
- Iafrate, A. John
Publication type:
Article
Evaluation of the Effect of Lorlatinib on CYP2B6, CYP2C9, UGT, and P-Glycoprotein Substrates in Patients with Advanced Non-Small Cell Lung Cancer.
Published in:
Clinical Pharmacokinetics, 2024, v. 63, n. 2, p. 171, doi. 10.1007/s40262-023-01309-4
By:
- Chen, Joseph;
- Bearz, Alessandra;
- Kim, Dong-Wan;
- Mamdani, Hirva;
- Bauman, Jessica;
- Chiari, Rita;
- Ou, Sai-Hong Ignatius;
- Solomon, Benjamin J.;
- Soo, Ross A.;
- Felip, Enriqueta;
- Shaw, Alice T.;
- Thurm, Holger;
- Clancy, Jill S.;
- Lee, Kimberly;
- O'Gorman, Melissa;
- Tanski, Cherie;
- Pithavala, Yazdi K.
Publication type:
Article
ALK Inhibitors in Non-Small Cell Lung Cancer: How Many Are Needed and How Should They Be Sequenced?
Published in:
Clinical Advances in Hematology & Oncology, 2017, v. 15, n. 12, p. 941
By:
- Shaw, Alice T.
Publication type:
Article
ALK Inhibitors in Non--Small Cell Lung Cancer: Crizotinib and Beyond.
Published in:
Clinical Advances in Hematology & Oncology, 2014, v. 12, n. 7, p. 429
By:
- Awad, Mark M.;
- Shaw, Alice T.
Publication type:
Article
Brain Penetration of Lorlatinib: Cumulative Incidences of CNS and Non-CNS Progression with Lorlatinib in Patients with Previously Treated ALK-Positive Non-Small-Cell Lung Cancer.
Published in:
2020
By:
- Bauer, Todd M.;
- Shaw, Alice T.;
- Johnson, Melissa L.;
- Navarro, Alejandro;
- Gainor, Justin F.;
- Thurm, Holger;
- Pithavala, Yazdi K.;
- Abbattista, Antonello;
- Peltz, Gerson;
- Felip, Enriqueta
Publication type:
journal article
Hypogonadism related to crizotinib therapy: implications for patient care.
Published in:
2012
By:
- Ramalingam SS;
- Shaw AT;
- Ramalingam, Suresh S;
- Shaw, Alice T
Publication type:
Editorial
Hypogonadism related to crizotinib therapy.
Published in:
Cancer (0008543X), 2012, v. 118, n. 21, p. E1, doi. 10.1002/cncr.27561
By:
- Ramalingam, Suresh S.;
- Shaw, Alice T.
Publication type:
Article
Clinical Management of Adverse Events Associated with Lorlatinib.
Published in:
Oncologist, 2019, v. 24, n. 8, p. 1103, doi. 10.1634/theoncologist.2018-0380
By:
- Bauer, Todd M.;
- Felip, Enriqueta;
- Solomon, Benjamin J.;
- Thurm, Holger;
- Peltz, Gerson;
- Chioda, Marc D.;
- Shaw, Alice T.
Publication type:
Article
Integration of Stereotactic Body Radiation Therapy With Tyrosine Kinase Inhibitors in Stage IV Oncogene-Driven Lung Cancer.
Published in:
Oncologist, 2016, v. 21, n. 8, p. 964, doi. 10.1634/theoncologist.2015-0508
By:
- Campo, Meghan;
- Al‐Halabi, Hani;
- Khandekar, Melin;
- Shaw, Alice T.;
- Sequist, Lecia V.;
- Willers, Henning
Publication type:
Article
Screening for ALK Rearrangements in Lung Cancer: Time for a New Generation of Diagnostics?
Published in:
2016
By:
- Dagogo‐Jack, Ibiayi;
- Shaw, Alice T.
Publication type:
Opinion
Novel Targets in Non-Small Cell Lung Cancer: ROS1 and RET Fusions.
Published in:
Oncologist, 2013, v. 18, n. 7, p. 865, doi. 10.1634/theoncologist.2013-0095
By:
- Gainor, Justin F.;
- Shaw, Alice T.
Publication type:
Article
Association between circulating tumor DNA burden and disease burden in patients with ALK-positive lung cancer.
Published in:
2020
By:
- Zhang, Eric W.;
- Dagogo‐Jack, Ibiayi;
- Kuo, Anderson;
- Rooney, Marguerite M.;
- Shaw, Alice T.;
- Digumarthy, Subba R.;
- Dagogo-Jack, Ibiayi
Publication type:
journal article
Tyrosine kinase gene rearrangements in epithelial malignancies.
Published in:
Nature Reviews Cancer, 2013, v. 13, n. 11, p. 772, doi. 10.1038/nrc3612
By:
- Shaw, Alice T.;
- Hsu, Peggy P.;
- Awad, Mark M.;
- Engelman, Jeffrey A.
Publication type:
Article

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