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Association Between a Common, Benign Genotype and Unnecessary Bone Marrow Biopsies Among African American Patients.
Published in:
2021
By:
- Van Driest, Sara L.;
- Abul-Husn, Noura S.;
- Glessner, Joseph T.;
- Bastarache, Lisa;
- Nirenberg, Sharon;
- Schildcrout, Jonathan S.;
- Eswarappa, Meghana S.;
- Belbin, Gillian M.;
- Shaffer, Christian M.;
- Mentch, Frank;
- Connolly, John;
- Shi, Mingjian;
- Stein, C. Michael;
- Roden, Dan M.;
- Hakonarson, Hakon;
- Cox, Nancy J.;
- Borinstein, Scott C.;
- Mosley, Jonathan D.
Publication type:
journal article
Genetic Thyrotropin Regulation of Atrial Fibrillation Risk Is Mediated Through an Effect on Height.
Published in:
2021
By:
- Mingjian Shi;
- Manouchehri, Ali M.;
- Shaffer, Christian M.;
- Vaitinadin, Nataraja Sarma;
- Hellwege, Jacklyn N.;
- Salem, Joe-Elie;
- Davis, Lea K.;
- Simmons, Jill H.;
- Roden, Dan M.;
- Shoemaker, M. Benjamin;
- Ferguson, Jane F.;
- Mosley, Jonathan D.;
- Shi, Mingjian
Publication type:
journal article
Pilot screening study of targeted genetic polymorphisms for association with seasonal influenza hospital admission.
Published in:
Journal of Medical Virology, 2018, v. 90, n. 3, p. 436, doi. 10.1002/jmv.24975
By:
- Carter, Tonia C.;
- Hebbring, Scott J.;
- Liu, Jixia;
- Mosley, Jonathan D.;
- Shaffer, Christian M.;
- Ivacic, Lynn C.;
- Kopitzke, Sarah;
- Stefanski, Elisha L.;
- Strenn, Rob;
- Sundaram, Maria E.;
- Meece, Jennifer;
- Brilliant, Murray H.;
- Ferdinands, Jill M.;
- Belongia, Edward A.
Publication type:
Article
Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy.
Published in:
PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0127791
By:
- Van Driest, Sara L.;
- McGregor, Tracy L.;
- Velez Edwards, Digna R.;
- Saville, Ben R.;
- Kitchner, Terrie E.;
- Hebbring, Scott J.;
- Brilliant, Murray;
- Jouni, Hayan;
- Kullo, Iftikhar J.;
- Creech, C. Buddy;
- Kannankeril, Prince J.;
- Vear, Susan I.;
- Brothers, Kyle B.;
- Bowton, Erica A.;
- Shaffer, Christian M.;
- Patel, Neelam;
- Delaney, Jessica T.;
- Bradford, Yuki;
- Wilson, Sarah;
- Olson, Lana M.
Publication type:
Article
Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study.
Published in:
European Heart Journal, 2023, v. 44, n. 21, p. 1927, doi. 10.1093/eurheartj/ehad142
By:
- Chen, Hao Yu;
- Dina, Christian;
- Small, Aeron M;
- Shaffer, Christian M;
- Levinson, Rebecca T;
- Helgadóttir, Anna;
- Capoulade, Romain;
- Munter, Hans Markus;
- Martinsson, Andreas;
- Cairns, Benjamin J;
- Trudsø, Linea C;
- Hoekstra, Mary;
- Burr, Hannah A;
- Marsh, Thomas W;
- Damrauer, Scott M;
- Dufresne, Line;
- Scouarnec, Solena Le;
- Messika-Zeitoun, David;
- Ranatunga, Dilrini K;
- Whitmer, Rachel A
Publication type:
Article
High-throughput framework for genetic analyses of adverse drug reactions using electronic health records.
Published in:
PLoS Genetics, 2021, v. 17, n. 6, p. 1, doi. 10.1371/journal.pgen.1009593
By:
- Zheng, Neil S.;
- Stone, Cosby A.;
- Jiang, Lan;
- Shaffer, Christian M.;
- Kerchberger, V. Eric;
- Chung, Cecilia P.;
- Feng, QiPing;
- Cox, Nancy J.;
- Stein, C. Michael;
- Roden, Dan M.;
- Denny, Joshua C.;
- Phillips, Elizabeth J.;
- Wei, Wei-Qi
Publication type:
Article
Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index.
Published in:
Frontiers in Genetics, 2014, v. 5, p. 1, doi. 10.3389/fgene.2014.00250
By:
- Cronin, Robert M.;
- Field, Julie R.;
- Bradford, Yuki;
- Shaffer, Christian M.;
- Carroll, Robert J.;
- Mosley, Jonathan D.;
- Bastarache, Lisa;
- Edwards, Todd L.;
- Hebbring, Scott J.;
- Lin, Simon;
- Hindorff, Lucia A.;
- Crane, Paul K.;
- Pendergrass, Sarah A.;
- Ritchie, Marylyn D.;
- Crawford, Dana C.;
- Pathak, Jyotishman;
- Bielinski, Suzette J.;
- Carrell, David S.;
- Crosslin, David R.;
- Ledbetter, David H.
Publication type:
Article
The polygenic architecture of left ventricular mass mirrors the clinical epidemiology.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64525-z
By:
- Mosley, Jonathan D.;
- Levinson, Rebecca T.;
- Farber-Eger, Eric;
- Edwards, Todd L.;
- Hellwege, Jacklyn N.;
- Hung, Adriana M.;
- Giri, Ayush;
- Shuey, Megan M.;
- Shaffer, Christian M.;
- Shi, Mingjian;
- Brittain, Evan L.;
- Chung, Wendy K.;
- Kullo, Iftikhar J.;
- Arruda-Olson, Adelaide M.;
- Jarvik, Gail P.;
- Larson, Eric B.;
- Crosslin, David R.;
- Williams, Marc S.;
- Borthwick, Ken M.;
- Hakonarson, Hakon
Publication type:
Article
A Genetic Approach to the Association Between PCSK9 and Sepsis.
Published in:
JAMA Network Open, 2019, v. 2, n. 9, p. e1911130, doi. 10.1001/jamanetworkopen.2019.11130
By:
- Feng, QiPing;
- Wei, Wei-Qi;
- Chaugai, Sandip;
- Carranza Leon, Barbara G.;
- Kawai, Vivian;
- Carranza Leon, Daniel A.;
- Jiang, Lan;
- Zhong, Xue;
- Liu, Ge;
- Ihegword, Andrea;
- Shaffer, Christian M.;
- Linton, MacRae F.;
- Chung, Cecilia P.;
- Stein, C. Michael
Publication type:
Article
Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection.
Published in:
JAMA Network Open, 2019, v. 2, n. 1, p. e187223, doi. 10.1001/jamanetworkopen.2018.7223
By:
- Feng, QiPing;
- Wei, Wei-Qi;
- Chaugai, Sandip;
- Leon, Barbara G. Carranza;
- Mosley, Jonathan D.;
- Leon, Daniel A. Carranza;
- Jiang, Lan;
- Ihegword, Andrea;
- Shaffer, Christian M.;
- Linton, MacRae F.;
- Chung, Cecilia P.;
- Stein, C. Michael
Publication type:
Article
Identifying genetically driven clinical phenotypes using linear mixed models.
Published in:
Nature Communications, 2016, v. 7, n. 4, p. 11433, doi. 10.1038/ncomms11433
By:
- Mosley, Jonathan D.;
- Witte, John S.;
- Larkin, Emma K.;
- Bastarache, Lisa;
- Shaffer, Christian M.;
- Karnes, Jason H.;
- Stein, C. Michael;
- Phillips, Elizabeth;
- Hebbring, Scott J.;
- Brilliant, Murray H.;
- Mayer, John;
- Ye, Zhan;
- Roden, Dan M.;
- Denny, Joshua C.
Publication type:
Article
Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants.
Published in:
Science Translational Medicine, 2017, v. 9, n. 389, p. 1, doi. 10.1126/scitranslmed.aai8708
By:
- Karnes, Jason H.;
- Bastarache, Lisa;
- Shaffer, Christian M.;
- Gaudieri, Silvana;
- Yaomin Xu;
- Glazer, Andrew M.;
- Mosley, Jonathan D.;
- Shilin Zhao;
- Raychaudhuri, Soumya;
- Mallal, Simon;
- Zhan Ye;
- Mayer, John G.;
- Brilliant, Murray H.;
- Hebbring, Scott J.;
- Roden, Dan M.;
- Phillips, Elizabeth J.;
- Denny, Joshua C.
Publication type:
Article
CMTR1 is associated with increased asthma exacerbations in patients taking inhaled corticosteroids.
Published in:
Immunity, Inflammation & Disease, 2015, v. 3, n. 4, p. 350, doi. 10.1002/iid3.73
By:
- Dahlin, Amber;
- Denny, Joshua;
- Roden, Dan M.;
- Brilliant, Murray H.;
- Ingram, Christie;
- Kitchner, Terrie E.;
- Linneman, James G.;
- Shaffer, Christian M.;
- Weeke, Peter;
- Xu, Hua;
- Kubo, Michiaki;
- Tamari, Mayumi;
- Clemmer, George L.;
- Ziniti, John;
- McGeachie, Michael J.;
- Tantisira, Kelan G.;
- Weiss, Scott T.;
- Wu, Ann Chen
Publication type:
Article
Genetic Determinants of Body Mass Index and Fasting Glucose Are Mediators of Grade 1 Diastolic Dysfunction.
Published in:
2022
By:
- Vaitinadin, Nataraja Sarma;
- Mingjian Shi;
- Shaffer, Christian M.;
- Farber-Eger, Eric;
- Lowery, Brandon D.;
- Agrawal, Vineet;
- Gupta, Deepak K.;
- Roden, Dan M.;
- Wells, Quinn S.;
- Mosley, Jonathan D.;
- Shi, Mingjian
Publication type:
journal article
The genetic architecture of plasma kynurenine includes cardiometabolic disease mechanisms associated with the SH2B3 gene.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95154-9
By:
- Bagheri, Minoo;
- Wang, Chuan;
- Shi, Mingjian;
- Manouchehri, Ali;
- Murray, Katherine T.;
- Murphy, Matthew B.;
- Shaffer, Christian M.;
- Singh, Kritika;
- Davis, Lea K.;
- Jarvik, Gail P.;
- Stanaway, Ian B.;
- Hebbring, Scott;
- Reilly, Muredach P.;
- Gerszten, Robert E.;
- Wang, Thomas J.;
- Mosley, Jonathan D.;
- Ferguson, Jane F.
Publication type:
Article
Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease.
Published in:
2020
By:
- Mosley, Jonathan D.;
- Gupta, Deepak K.;
- Tan, Jingyi;
- Yao, Jie;
- Wells, Quinn S.;
- Shaffer, Christian M.;
- Kundu, Suman;
- Robinson-Cohen, Cassianne;
- Psaty, Bruce M.;
- Rich, Stephen S.;
- Post, Wendy S.;
- Guo, Xiuqing;
- Rotter, Jerome I;
- Roden, Dan M.;
- Gerszten, Robert E.;
- Wang, Thomas J.
Publication type:
journal article
Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation.
Published in:
2018
By:
- Choi, Seung Hoan;
- Weng, Lu-Chen;
- Roselli, Carolina;
- Lin, Honghuang;
- Haggerty, Christopher M.;
- Shoemaker, M. Benjamin;
- Barnard, John;
- Arking, Dan E.;
- Chasman, Daniel I.;
- Albert, Christine M.;
- Chaffin, Mark;
- Tucker, Nathan R.;
- Smith, Jonathan D.;
- Gupta, Namrata;
- Gabriel, Stacey;
- Margolin, Lauren;
- Shea, Marisa A.;
- Shaffer, Christian M.;
- Yoneda, Zachary T.;
- Boerwinkle, Eric
Publication type:
journal article
Comparison of HLA allelic imputation programs.
Published in:
PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0172444
By:
- Karnes, Jason H.;
- Shaffer, Christian M.;
- Bastarache, Lisa;
- Gaudieri, Silvana;
- Glazer, Andrew M.;
- Steiner, Heidi E.;
- Mosley, Jonathan D.;
- Mallal, Simon;
- Denny, Joshua C.;
- Phillips, Elizabeth J.;
- Roden, Dan M.
Publication type:
Article
Influence of Human Leukocyte Antigen ( HLA) Alleles and Killer Cell Immunoglobulin-Like Receptors ( KIR) Types on Heparin-Induced Thrombocytopenia ( HIT).
Published in:
Pharmacotherapy, 2017, v. 37, n. 9, p. 1164, doi. 10.1002/phar.1983
By:
- Karnes, Jason H.;
- Shaffer, Christian M.;
- Cronin, Robert;
- Bastarache, Lisa;
- Gaudieri, Silvana;
- James, Ian;
- Pavlos, Rebecca;
- Steiner, Heidi E.;
- Mosley, Jonathan D.;
- Mallal, Simon;
- Denny, Joshua C.;
- Phillips, Elizabeth J.;
- Roden, Dan M.
Publication type:
Article
A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05624-4
By:
- Mosley, Jonathan D.;
- Feng, QiPing;
- Wells, Quinn S.;
- Van Driest, Sara L.;
- Shaffer, Christian M.;
- Edwards, Todd L.;
- Bastarache, Lisa;
- Wei, Wei-Qi;
- Davis, Lea K.;
- McCarty, Catherine A.;
- Thompson, Will;
- Chute, Christopher G.;
- Jarvik, Gail P.;
- Gordon, Adam S.;
- Palmer, Melody R.;
- Crosslin, David R.;
- Larson, Eric B.;
- Carrell, David S.;
- Kullo, Iftikhar J.;
- Pacheco, Jennifer A.
Publication type:
Article
CYP2C19 and CES1 polymorphisms and efficacy of clopidogrel and aspirin dual antiplatelet therapy in patients with symptomatic intracranial atherosclerotic disease.
Published in:
Journal of Neurosurgery, 2016, v. 124, n. 6, p. 1746, doi. 10.3171/2015.6.JNS15795
By:
- Hoh, Brian L.;
- Gong, Yan;
- McDonough, Caitrin W.;
- Waters, Michael F.;
- Royster, Adrienne J.;
- Sheehan, Tiffany O.;
- Burkley, Ben;
- Langaee, Taimour Y.;
- Mocco, J.;
- Zuckerman, Scott L.;
- Mummareddy, Nishit;
- Stephens II, Marcus L.;
- Ingram, Christie;
- Shaffer, Christian M.;
- Denny, Joshua C.;
- Brilliant, Murray H.;
- Kitchner, Terrie E.;
- Linneman, James G.;
- Roden, Dan M.;
- Johnson, Julie A.
Publication type:
Article
Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2.
Published in:
BMC Genomics, 2012, v. 13, n. 1, p. 189, doi. 10.1186/1471-2164-13-189
By:
- Garcia, Christina B.;
- Shaffer, Christian M.;
- Eid, Josiane E.
Publication type:
Article

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