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Sclerostin Depletion Induces Inflammation in the Bone Marrow of Mice.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9111, doi. 10.3390/ijms22179111
By:
- Donham, Cristine;
- Chicana, Betsabel;
- Robling, Alexander G.;
- Mohamed, Asmaa;
- Elizaldi, Sonny;
- Chi, Michael;
- Freeman, Brian;
- Millan, Alberto;
- Murugesh, Deepa K.;
- Hum, Nicholas R.;
- Sebastian, Aimy;
- Loots, Gabriela G.;
- Manilay, Jennifer O.
Publication type:
Article
Antibiotic Treatment Prior to Injury Improves Post-Traumatic Osteoarthritis Outcomes in Mice.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6424, doi. 10.3390/ijms21176424
By:
- Mendez, Melanie E.;
- Murugesh, Deepa K.;
- Sebastian, Aimy;
- Hum, Nicholas R.;
- McCloy, Summer A.;
- Kuhn, Edward A.;
- Christiansen, Blaine A.;
- Loots, Gabriela G.
Publication type:
Article
Global Gene Expression Analysis Identifies Age-Related Differences in Knee Joint Transcriptome during the Development of Post-Traumatic Osteoarthritis in Mice.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 364, doi. 10.3390/ijms21010364
By:
- Sebastian, Aimy;
- Murugesh, Deepa K.;
- Mendez, Melanie E.;
- Hum, Nicholas R.;
- Rios-Arce, Naiomy D.;
- McCool, Jillian L.;
- Christiansen, Blaine A.;
- Loots, Gabriela G.
Publication type:
Article
Methionine Adenosyltransferase 1a (MAT1A) Enhances Cell Survival During Chemotherapy Treatment and is Associated with Drug Resistance in Bladder Cancer PDX Mice.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 20, p. 4983, doi. 10.3390/ijms20204983
By:
- Martin, Kelly A.;
- Hum, Nicholas R.;
- Sebastian, Aimy;
- He, Wei;
- Siddiqui, Salma;
- Ghosh, Paramita M.;
- Pan, Chong-xian;
- de Vere White, Ralph;
- Loots, Gabriela G.
Publication type:
Article
Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression.
Published in:
International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2657, doi. 10.3390/ijms19092657
By:
- Sebastian, Aimy;
- Chang, Jiun C.;
- Mendez, Melanie E.;
- Murugesh, Deepa K.;
- Hatsell, Sarah;
- Economides, Aris N.;
- Christiansen, Blaine A.;
- Loots, Gabriela G.
Publication type:
Article
Cancer-Osteoblast Interaction Reduces Sost Expression in Osteoblasts and Up-Regulates lncRNA MALAT1 in Prostate Cancer.
Published in:
Microarrays (2076-3905), 2015, v. 4, n. 4, p. 503, doi. 10.3390/microarrays4040503
By:
- Sebastian, Aimy;
- Hum, Nicholas R.;
- Hudson, Bryan D.;
- Loots, Gabriela G.
Publication type:
Article
Loss of Cadherin-11 in pancreatic ductal adenocarcinoma alters tumor-immune microenvironment.
Published in:
Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1286861
By:
- Sebastian, Aimy;
- Martin, Kelly A.;
- Peran, Ivana;
- Hum, Nicholas R.;
- Leon, Nicole F.;
- Amiri, Beheshta;
- Wilson, Stephen P.;
- Coleman, Matthew A.;
- Wheeler, Elizabeth K.;
- Byers, Stephen W.;
- Loots, Gabriela G.
Publication type:
Article
Single-cell RNA-Seq reveals changes in immune landscape in post-traumatic osteoarthritis.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.938075
By:
- Sebastian, Aimy;
- Hum, Nicholas R.;
- McCool, Jillian L.;
- Wilson, Stephen P.;
- Murugesh, Deepa K.;
- Martin, Kelly A.;
- Rios-Arce, Naiomy Deliz;
- Amiri, Beheshta;
- Christiansen, Blaine A.;
- Loots, Gabriela G.
Publication type:
Article
Human Protein Reference Database—2009 update.
Published in:
Nucleic Acids Research, 2009, v. 37, n. suppl_1, p. D767, doi. 10.1093/nar/gkn892
By:
- Keshava Prasad, T. S.;
- Goel, Renu;
- Kandasamy, Kumaran;
- Keerthikumar, Shivakumar;
- Kumar, Sameer;
- Mathivanan, Suresh;
- Telikicherla, Deepthi;
- Raju, Rajesh;
- Shafreen, Beema;
- Venugopal, Abhilash;
- Balakrishnan, Lavanya;
- Marimuthu, Arivusudar;
- Banerjee, Sutopa;
- Somanathan, Devi S.;
- Sebastian, Aimy;
- Rani, Sandhya;
- Ray, Somak;
- Harrys Kishore, C. J.;
- Kanth, Sashi;
- Ahmed, Mukhtar
Publication type:
Article
SOST Inhibits Prostate Cancer Invasion.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142058
By:
- Hudson, Bryan D.;
- Hum, Nicholas R.;
- Thomas, Cynthia B.;
- Kohlgruber, Ayano;
- Sebastian, Aimy;
- Collette, Nicole M.;
- Coleman, Matthew A.;
- Christiansen, Blaine A.;
- Loots, Gabriela G.
Publication type:
Article
MAVS mediates a protective immune response in the brain to Rift Valley fever virus.
Published in:
PLoS Pathogens, 2022, v. 18, n. 5, p. 1, doi. 10.1371/journal.ppat.1010231
By:
- Hum, Nicholas R.;
- Bourguet, Feliza A.;
- Sebastian, Aimy;
- Lam, Doris;
- Phillips, Ashlee M.;
- Sanchez, Kristina R.;
- Rasley, Amy;
- Loots, Gabriela G.;
- Weilhammer, Dina R.
Publication type:
Article
Virtual Activity Profiling of Bioactive Molecules by 1D Fingerprinting.
Published in:
Molecular Informatics, 2010, v. 29, n. 11, p. 773, doi. 10.1002/minf.201000075
By:
- Sebastian, Aimy;
- Bender, Andreas;
- Ramakrishnan, Vibin
Publication type:
Article
Single-Cell Transcriptomic Analysis of Tumor-Derived Fibroblasts and Normal Tissue-Resident Fibroblasts Reveals Fibroblast Heterogeneity in Breast Cancer.
Published in:
Cancers, 2020, v. 12, n. 5, p. 1307, doi. 10.3390/cancers12051307
By:
- Sebastian, Aimy;
- Hum, Nicholas R.;
- Martin, Kelly A.;
- Gilmore, Sean F.;
- Peran, Ivana;
- Byers, Stephen W.;
- Wheeler, Elizabeth K.;
- Coleman, Matthew A.;
- Loots, Gabriela G.
Publication type:
Article
Comparative Molecular Analysis of Cancer Behavior Cultured In Vitro, In Vivo, and Ex Vivo.
Published in:
Cancers, 2020, v. 12, n. 3, p. 690, doi. 10.3390/cancers12030690
By:
- Hum, Nicholas R.;
- Sebastian, Aimy;
- Gilmore, Sean F.;
- He, Wei;
- Martin, Kelly A.;
- Hinckley, Aubree;
- Dubbin, Karen R.;
- Moya, Monica L.;
- Wheeler, Elizabeth K.;
- Coleman, Matthew A.;
- Loots, Gabriela G.
Publication type:
Article
Altered canalicular remodeling associated with femur fracture in mice.
Published in:
Journal of Orthopaedic Research, 2022, v. 40, n. 4, p. 891, doi. 10.1002/jor.25119
By:
- Emami, Armaun J.;
- Sebastian, Aimy;
- Lin, Yu‐Yang;
- Yee, Cristal S.;
- Osipov, Benjamin;
- Loots, Gabriela G.;
- Alliston, Tamara;
- Christiansen, Blaine A.
Publication type:
Article
Global molecular changes in a tibial compression induced ACL rupture model of post-traumatic osteoarthritis.
Published in:
Journal of Orthopaedic Research, 2017, v. 35, n. 3, p. 474, doi. 10.1002/jor.23263
By:
- Chang, Jiun C.;
- Sebastian, Aimy;
- Murugesh, Deepa K.;
- Hatsell, Sarah;
- Economides, Aris N.;
- Christiansen, Blaine A.;
- Loots, Gabriela G.
Publication type:
Article
Space flight associated changes in astronauts' plasma‐derived small extracellular vesicle microRNA: Biomarker identification.
Published in:
Clinical & Translational Medicine, 2022, v. 12, n. 6, p. 1, doi. 10.1002/ctm2.845
By:
- Goukassian, David;
- Arakelyan, Arsen;
- Brojakowska, Agnieszka;
- Bisserier, Malik;
- Hakobyan, Siras;
- Hadri, Lahouaria;
- Rai, Amit Kumar;
- Evans, Angela;
- Sebastian, Aimy;
- Truongcao, May;
- Gonzalez, Carolina;
- Bajpai, Anamika;
- Cheng, Zhongjian;
- Dubey, Praveen Kumar;
- Addya, Sankar;
- Mills, Paul;
- Walsh, Kenneth;
- Kishore, Raj;
- Coleman, Matt;
- Garikipati, Venkata Naga Srikanth
Publication type:
Article
Diabetes Promotes Mild Osteoarthritis in The Streptozotocin‐ Induced Diabetic Mouse Model.
Published in:
FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02490
By:
- Rios Arce, Naiomy;
- Murugesh, Deepa;
- Hum, Nicholas;
- Sebastian, Aimy;
- Jbeily, Elias;
- Christiansen, Blaine;
- Loots, Gabriela
Publication type:
Article
Functional and transcriptional characterization of complex neuronal co-cultures.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67691-2
By:
- Enright, Heather A.;
- Lam, Doris;
- Sebastian, Aimy;
- Sales, Ana Paula;
- Cadena, Jose;
- Hum, Nicholas R.;
- Osburn, Joanne J.;
- Peters, Sandra K. G.;
- Petkus, Bryan;
- Soscia, David A.;
- Kulp, Kristen S.;
- Loots, Gabriela G.;
- Wheeler, Elizabeth K.;
- Fischer, Nicholas O.
Publication type:
Article
Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of GATA1 and STAG2 Mutations in Induced Pluripotent Stem Cells with Trisomy 21.
Published in:
Cells (2073-4409), 2022, v. 11, n. 4, p. 628, doi. 10.3390/cells11040628
By:
- Barwe, Sonali P.;
- Sebastian, Aimy;
- Sidhu, Ishnoor;
- Kolb, Edward Anders;
- Gopalakrishnapillai, Anilkumar
Publication type:
Article
Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes.
Published in:
Cells (2073-4409), 2021, v. 10, n. 6, p. 1462, doi. 10.3390/cells10061462
By:
- Sebastian, Aimy;
- McCool, Jillian L.;
- Hum, Nicholas R.;
- Murugesh, Deepa K.;
- Wilson, Stephen P.;
- Christiansen, Blaine A.;
- Loots, Gabriela G.
Publication type:
Article
Emerging Role of Exosomal Long Non-coding RNAs in Spaceflight-Associated Risks in Astronauts.
Published in:
Frontiers in Genetics, 2022, v. 12, p. 1, doi. 10.3389/fgene.2021.812188
By:
- Bisserier, Malik;
- Saffran, Nathaniel;
- Brojakowska, Agnieszka;
- Sebastian, Aimy;
- Evans, Angela Clare;
- Coleman, Matthew A.;
- Walsh, Kenneth;
- Mills, Paul J.;
- Garikipati, Venkata Naga Srikanth;
- Arakelyan, Arsen;
- Hadri, Lahouaria;
- Goukassian, David A.
Publication type:
Article
IL-17A Increases Doxorubicin Efficacy in Triple Negative Breast Cancer.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.928474
By:
- Hum, Nicholas R.;
- Sebastian, Aimy;
- Martin, Kelly A.;
- Rios-Arce, Naiomy D.;
- Gilmore, Sean F.;
- Gravano, David M.;
- Wheeler, Elizabeth K.;
- Coleman, Matthew A.;
- Loots, Gabriela G.
Publication type:
Article
Simulated Microgravity Alters Gene Regulation Linked to Immunity and Cardiovascular Disease.
Published in:
Genes, 2024, v. 15, n. 8, p. 975, doi. 10.3390/genes15080975
By:
- Tahimic, Candice G. T.;
- Steczina, Sonette;
- Sebastian, Aimy;
- Hum, Nicholas R.;
- Abegaz, Metadel;
- Terada, Masahiro;
- Cimini, Maria;
- Goukassian, David A.;
- Schreurs, Ann-Sofie;
- Hoban-Higgins, Tana M.;
- Fuller, Charles A.;
- Loots, Gabriela G.;
- Globus, Ruth K.;
- Shirazi-Fard, Yasaman
Publication type:
Article
LPS‐Induced Inflammation Prior to Injury Exacerbates the Development of Post‐Traumatic Osteoarthritis in Mice.
Published in:
Journal of Bone & Mineral Research, 2020, v. 35, n. 11, p. 2229, doi. 10.1002/jbmr.4117
By:
- Mendez, Melanie E;
- Sebastian, Aimy;
- Murugesh, Deepa K;
- Hum, Nicholas R;
- McCool, Jillian L;
- Hsia, Allison W;
- Christiansen, Blaine A;
- Loots, Gabriela G
Publication type:
Article
Expression of a Degradation‐Resistant β‐Catenin Mutant in Osteocytes Protects the Skeleton From Mechanodeprivation‐Induced Bone Wasting.
Published in:
Journal of Bone & Mineral Research, 2019, v. 34, n. 10, p. 1964, doi. 10.1002/jbmr.3812
By:
- Bullock, Whitney A;
- Hoggatt, April M;
- Horan, Daniel J;
- Lewis, Karl J;
- Yokota, Hiroki;
- Hann, Steven;
- Warman, Matthew L;
- Sebastian, Aimy;
- Loots, Gabriela G;
- Pavalko, Fredrick M;
- Robling, Alexander G
Publication type:
Article
SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury.
Published in:
Journal of Bone & Mineral Research, 2018, v. 33, n. 6, p. 1105, doi. 10.1002/jbmr.3397
By:
- Chang, Jiun C.;
- Christiansen, Blaine A.;
- Murugesh, Deepa K.;
- Sebastian, Aimy;
- Hum, Nicholas R.;
- Collette, Nicole M.;
- Hatsell, Sarah;
- Economides, Aris N.;
- Blanchette, Craig D.;
- Loots, Gabriela G.
Publication type:
Article
Eucalyptus Wood Smoke Extract Elicits a Dose-Dependent Effect in Brain Endothelial Cells.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 19, p. 10288, doi. 10.3390/ijms251910288
By:
- You, Dorothy J.;
- Gorman, Bria M.;
- Goshi, Noah;
- Hum, Nicholas R.;
- Sebastian, Aimy;
- Kim, Yong Ho;
- Enright, Heather A.;
- Buchholz, Bruce A.
Publication type:
Article
Preexisting Type 1 Diabetes Mellitus Blunts the Development of Posttraumatic Osteoarthritis.
Published in:
JBMR Plus, 2022, v. 6, n. 5, p. 1, doi. 10.1002/jbm4.10625
By:
- Rios‐Arce, Naiomy D;
- Murugesh, Deepa K;
- Hum, Nicholas R;
- Sebastian, Aimy;
- Jbeily, Elias H;
- Christiansen, Blaine A;
- Loots, Gabriela G
Publication type:
Article
Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts.
Published in:
PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0188264
By:
- Sebastian, Aimy;
- Hum, Nicholas R.;
- Murugesh, Deepa K.;
- Hatsell, Sarah;
- Economides, Aris N.;
- Loots, Gabriela G.
Publication type:
Article
Biphasic response of human iPSC-derived neural network activity following exposure to a sarin-surrogate nerve agent.
Published in:
Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1378579
By:
- Bogguri, Chandrakumar;
- George, Vivek Kurien;
- Amiri, Beheshta;
- Ladd, Alexander;
- Hum, Nicholas R.;
- Sebastian, Aimy;
- Enright, Heather A.;
- Valdez, Carlos A.;
- Mundhenk, T. Nathan;
- Cadena, Jose;
- Lam, Doris
Publication type:
Article

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