OpenURL Connection Search

Select item for more details and to access through your institution.

Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
Published in:
Angewandte Chemie, 2016, v. 128, n. 33, p. 9753, doi. 10.1002/ange.201603797
By:
- Liang, Steven H.;
- Chen, Jinshan Michael;
- Normandin, Marc D.;
- Chang, Jeanne S.;
- Chang, George C.;
- Taylor, Christine K.;
- Trapa, Patrick;
- Plummer, Mark S.;
- Para, Kimberly S.;
- Conn, Edward L.;
- Lopresti ‐ Morrow, Lori;
- Lanyon, Lorraine F.;
- Cook, James M.;
- Richter, Karl E. G.;
- Nolan, Charlie E.;
- Schachter, Joel B.;
- Janat, Fouad;
- Che, Ye;
- Shanmugasundaram, Veerabahu;
- Lefker, Bruce A.
Publication type:
Article
High Throughput Monitoring of Amyloid-β42 Assembly into Soluble Oligomers Achieved by Sensitive Conformation State-Dependent Immunoassays.
Published in:
Journal of Alzheimer's Disease, 2011, v. 25, n. 4, p. 655, doi. 10.3233/JAD-2011-102022
By:
- Zhao, Wei-Qin;
- Toolan, Dawn;
- Hepler, Robert W.;
- Wolfe, Abigail L.;
- Yu, Yuanjiang;
- Price, Eric;
- Uebele, Victor N.;
- Schachter, Joel B.;
- Reynolds, Ian J.;
- Renger, John J.;
- McCampbell, Alexander;
- Ray, William J.
Publication type:
Article
Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.
Published in:
Angewandte Chemie International Edition, 2016, v. 55, n. 33, p. 9601, doi. 10.1002/anie.201603797
By:
- Liang, Steven H.;
- Chen, Jinshan Michael;
- Normandin, Marc D.;
- Chang, Jeanne S.;
- Chang, George C.;
- Taylor, Christine K.;
- Trapa, Patrick;
- Plummer, Mark S.;
- Para, Kimberly S.;
- Conn, Edward L.;
- Lopresti‐Morrow, Lori;
- Lanyon, Lorraine F.;
- Cook, James M.;
- Richter, Karl E. G.;
- Nolan, Charlie E.;
- Schachter, Joel B.;
- Janat, Fouad;
- Che, Ye;
- Shanmugasundaram, Veerabahu;
- Lefker, Bruce A.
Publication type:
Article
An examination of deoxyadenosine 5′( α-thio)triphosphate as a ligand to define P2Y receptors and its selectivity as a low potency partial agonist of the P2Y1 receptor.
Published in:
British Journal of Pharmacology, 1997, v. 121, n. 2, p. 338, doi. 10.1038/sj.bjp.0701136
By:
- Schachter, Joel B;
- Kendall Harden, T
Publication type:
Article
PHENOTYPIC SCREENING FOR NOVEL INHIBITORS OF TAU AGGREGATION IN HUMAN IPSC-DERIVED NEURONS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P963, doi. 10.1016/j.jalz.2017.06.1293
By:
- Voleti, Bhavya;
- Warren, Lee;
- Usenovic, Marija;
- Schachter, Joel B.;
- Zhou, Heather;
- Walji, Abbas;
- Luo, Bin;
- Li, Jing;
- Parmentier-Batteur, Sophie
Publication type:
Article
INTERVENTION OF TAU PATHOLOGY PREVENTS BEHAVIORAL CHANGES IN RTG4510 MOUSE MODEL OF TAUOPATHY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P845, doi. 10.1016/j.jalz.2016.06.1731
By:
- Wang, Xiaohai;
- Smith, Karen;
- Pearson, Michelle;
- Hughes, Anna;
- Cosden, Mali;
- Marcus, Jacob;
- Hess, Fred;
- Savage, Mary;
- Renger, John J.;
- Rosahl, Thomas W.;
- Smith, Sean M.;
- Schachter, Joel B.;
- Uslaner, Jason M.
Publication type:
Article
EARLY CLINICAL RESULTS AND PRECLINICAL VALIDATION OF THE O-GLCNACASE (OGA) INHIBITOR MK-8719 AS A NOVEL THERAPEUTIC FOR THE TREATMENT OF TAUOPATHIES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P261, doi. 10.1016/j.jalz.2016.06.469
By:
- Smith, Sean M.;
- Struyk, Arie;
- Jonathan, Daniel;
- Declercq, Ruben;
- Marcus, Jacob;
- Toolan, Dawn;
- Wang, Xiaohai;
- Schachter, Joel B.;
- Cosden, Mali;
- Pearson, Michelle;
- Hess, Fred;
- Selnick, Harold;
- Salinas, Cristian;
- Li, Wenping;
- Duffy, Joseph;
- McEachern, Ernest;
- Vocadlo, David;
- Renger, John J.;
- Eric, Hostetler D.;
- Forman, Mark
Publication type:
Article
A CELLULAR EXPRESSION MODEL OF TAU HYPERPHOSPHORYLATION AND AGGREGATION THAT DOES NOT UTILIZE FRONTOTEMPORAL DEMENTIA MUTATIONS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P842, doi. 10.1016/j.jalz.2016.06.1724
By:
- Schachter, Joel B.;
- Cosden, Mali;
- Meteer, Jeffrey;
- Majercak, John;
- Hess, Fred;
- Niroomand, Shahriar;
- Renger, John J.;
- Winrow, Christopher J.
Publication type:
Article
AM-03: Do selective inhibitors discern the relative roles of kinases in the regulation of tau phosphorylation?
Published in:
2007
By:
- Schachter, Joel B.;
- Lau, Lit- Fui;
- Richter, Karl E.G.;
- Nolan, Charles E.;
- Cook, James M.
Publication type:
Abstract
Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 12, p. 3090, doi. 10.1523/JNEUROSCI.4854-06.2007
By:
- Planel, Emmanuel;
- Richter, Karl E. G.;
- Nolan, Charles E.;
- Finley, James E.;
- Li Liu;
- Yi Wen;
- Krishnamurthy, Pavan;
- Herman, Mathieu;
- Lili Wang;
- Schachter, Joel B.;
- Nelson, Robert B.;
- Lit-Fui Lau;
- Duff, Karen E.
Publication type:
Article
Avian and human homologues of the P2Y1 receptor: Pharmacological, signaling, and molecular properties.
Published in:
Drug Development Research, 1996, v. 39, n. 3/4, p. 253, doi. 10.1002/(SICI)1098-2299(199611/12)39:3/4<253::AID-DDR4>3.0.CO;2-Q
By:
- Boyer, Jose L.;
- Schachter, Joel B.;
- Sromek, Susan M.;
- Palmer, R. Kyle;
- Jacobson, Kenneth A.;
- Nicholas, Robert A.;
- Harden, T. Kendall
Publication type:
Article
Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy.
Published in:
PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0195486
By:
- Wang, Xiaohai;
- Smith, Karen;
- Pearson, Michelle;
- Hughes, Anna;
- Cosden, Mali L.;
- Marcus, Jacob;
- Hess, J. Fred;
- Savage, Mary J.;
- Rosahl, Thomas;
- Smith, Sean M.;
- Schachter, Joel B.;
- Uslaner, Jason M.
Publication type:
Article

Found: 12

Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.

High Throughput Monitoring of Amyloid-β<sub>42</sub> Assembly into Soluble Oligomers Achieved by Sensitive Conformation State-Dependent Immunoassays.

Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.

An examination of deoxyadenosine 5′( α-thio)triphosphate as a ligand to define P2Y receptors and its selectivity as a low potency partial agonist of the P2Y<sub>1</sub> receptor.

PHENOTYPIC SCREENING FOR NOVEL INHIBITORS OF TAU AGGREGATION IN HUMAN IPSC-DERIVED NEURONS.

INTERVENTION OF TAU PATHOLOGY PREVENTS BEHAVIORAL CHANGES IN RTG4510 MOUSE MODEL OF TAUOPATHY.

EARLY CLINICAL RESULTS AND PRECLINICAL VALIDATION OF THE O-GLCNACASE (OGA) INHIBITOR MK-8719 AS A NOVEL THERAPEUTIC FOR THE TREATMENT OF TAUOPATHIES.

A CELLULAR EXPRESSION MODEL OF TAU HYPERPHOSPHORYLATION AND AGGREGATION THAT DOES NOT UTILIZE FRONTOTEMPORAL DEMENTIA MUTATIONS.

AM-03: Do selective inhibitors discern the relative roles of kinases in the regulation of tau phosphorylation?

Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia.

Avian and human homologues of the P2Y<sub>1</sub> receptor: Pharmacological, signaling, and molecular properties.

Early intervention of tau pathology prevents behavioral changes in the rTg4510 mouse model of tauopathy.