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A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
- Published in:
- Genetics, 2018, v. 209, n. 1, p. 51, doi. 10.1534/genetics.117.300673
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- Publication type:
- Article
APOE ε4 and exercise interact in a sex-specific manner to modulate dementia risk factors.
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- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2022, v. 8, n. 1, p. 1, doi. 10.1002/trc2.12308
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- Publication type:
- Article
Model organism development and evaluation for late‐onset Alzheimer's disease: MODEL‐AD.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12110
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- Publication type:
- Article
Improving preclinical to clinical translation in Alzheimer's disease research.
- Published in:
- Alzheimer's & Dementia: Translational Research & Clinical Interventions, 2020, v. 6, n. 1, p. 1, doi. 10.1002/trc2.12038
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- Publication type:
- Article
The Alzheimer's disease protective R522 variant of PLCg2, consistently enhances PLCγ2 activation, depleting PI(4,5)P<sub>2</sub> levels and altering cell function in in vitro and in vivo assays: Developing topics.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047404
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- Article
N‐of‐1‐pathways transcriptomic analysis reveals distinct subtypes of Alzheimer's disease: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046575
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- Publication type:
- Article
Deep phenotyping of the 5XFAD model: IU/JAX/PITT MODEL‐AD center: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045981
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- Publication type:
- Article
Exercise as a strategy to prevent APOE<sup>ε4</sup>‐dependent phenotypes: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045887
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- Publication type:
- Article
Transcriptomic profiling of APOE4/Trem2*R47H mouse models for late‐onset Alzheimer's disease: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045390
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- Publication type:
- Article
Hallmarks of late‐onset Alzheimer's disease in a humanized mouse model: Development of new models and analysis methods/screening studies/platforms.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045162
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- Publication type:
- Article
Leveraging mouse genetic diversity to investigate the role of brain myeloid cells in Alzheimer's disease: Inflammation: From basic science to biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044978
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- Publication type:
- Article
Identification and characterization of immune‐focused therapeutic targets in the MODEL‐AD and TREAT‐AD consortia: Microbiome in Alzheimer's disease: Pathogenesis and treatment implications.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044157
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- Publication type:
- Article
In vivo testing of the role of Alzheimer's disease coding variants: Functionalizing genetic variants in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043896
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- Publication type:
- Article
Neurovascular uncoupling of cerebral blood flow and glucose metabolism in APOE4, TREM2, and APOE4.TREM2 mice: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041531
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- Publication type:
- Article
Pharmacokinetic, pharmacodynamic and transcriptomic analyses of verubecestat treatment in 5XFAD mice: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041491
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- Publication type:
- Article
Translating genetic risk variants in disease‐associated enhancers into novel mouse models of Alzheimer's disease: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040529
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- Publication type:
- Article
A common risk variant in the MTHFR gene contributes to age‐related cerebrovascular dysfunction in VCID: Development of new models and analysis methods/novel assays and technologies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038657
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- Publication type:
- Article
O5‐10‐01: ENHANCED FUNCTION OF PLCG2 VARIANT P522R IN MACROPHAGES AND MICROGLIA IS ASSOCIATED WITH PROTECTION FROM ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1641, doi. 10.1016/j.jalz.2019.06.4888
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- Article
P4‐098: TRANSCRIPTOMIC ALTERATIONS DRIVEN BY THE TREM2*R47H ALLELE VARY ACROSS DIFFERENT TRANSGENIC MOUSE MODELS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1312, doi. 10.1016/j.jalz.2019.06.3758
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- Publication type:
- Article
P4‐087: A COMMON RISK VARIANT IN THE MTHFR GENE CONTRIBUTES TO CEREBROVASCULAR DYSFUNCTION IN MIXED DEMENTIA.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1308, doi. 10.1016/j.jalz.2019.06.3747
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- Publication type:
- Article
P4‐091: THE TREM2*R47H VARIANT ALTERS EXPRESSION AND FUNCTION IN MOUSE MODELS OF ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1309, doi. 10.1016/j.jalz.2019.06.3751
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- Publication type:
- Article
P4‐079: CRITICAL EVALUATION OF THE PHARMACOKINETICS OF VERUBECESTAT IN AGED 5XFAD MICE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1304, doi. 10.1016/j.jalz.2019.06.3739
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- Publication type:
- Article
O4‐09‐01: LEVERAGING MOUSE GENETIC DIVERSITY TO INVESTIGATE THE ROLE OF BRAIN MYELOID CELLS IN ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1255, doi. 10.1016/j.jalz.2019.06.4788
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- Publication type:
- Article
P3‐142: STRATIFICATION OF ALZHEIMER'S PATIENTS USING POSTMORTEM BRAIN CO‐EXPRESSION DATA REVEALS NOVEL GENETIC MODIFIERS MEDIATING INFLAMMATORY AGING.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P986, doi. 10.1016/j.jalz.2019.06.3170
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- Publication type:
- Article
P3‐111: METABOLIC ASSESSMENT OF GENETICALLY DISTINCT MOUSE POPULATIONS: STRAIN MATTERS IN MOUSE MODELS OF ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P972, doi. 10.1016/j.jalz.2019.06.3139
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- Publication type:
- Article
P2‐133: INITIAL CHARACTERIZATION OF NOVEL MOUSE MODELS OF LATE ONSET ALZHEIMER'S DISEASE BASED ON HUMAN GENETIC ASSOCIATIONS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P623, doi. 10.1016/j.jalz.2019.06.2540
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- Publication type:
- Article
P2‐131: NOVEL APOE4.TREM2*R47H MOUSE MODEL: A BETTER TOOL FOR LATE‐ONSET ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P622, doi. 10.1016/j.jalz.2019.06.2538
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- Publication type:
- Article
P2‐105: A NOVEL SYSTEMS BIOLOGY APPROACH TO EVALUATE MOUSE MODELS OF LATE ONSET ALZHEIMER'S DISEASE: NCOUNTER MOUSE AD PANEL.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P612, doi. 10.1016/j.jalz.2019.06.2512
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- Publication type:
- Article
F1‐07‐03: ALZHEIMER'S SUSCEPTIBILITY GENES IMPLICATE MICROGLIAL ACTIVITY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P188, doi. 10.1016/j.jalz.2019.06.4395
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- Publication type:
- Article
P4‐031: NOVEL MODELS OF LATE‐ONSET ALZHEIMER'S DISEASE BASED ON GWAS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1445, doi. 10.1016/j.jalz.2018.06.2433
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- Publication type:
- Article
P4‐028: CHARACTERIZING THE APOE4/TREM2*R47H MOUSE MODEL FOR LATE ONSET ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1444, doi. 10.1016/j.jalz.2018.06.2430
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- Publication type:
- Article
O4‐01‐06: WHOLE‐EXOME ANALYSIS OF LATE‐ONSET ALZHEIMER'S DISEASE REVEALS NOVEL CANDIDATE GENES INVOLVED IN COGNITIVE FUNCTION.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1402, doi. 10.1016/j.jalz.2018.06.2914
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- Publication type:
- Article
P2‐045: THE MODEL‐AD CONSORTIUM PRECLINICAL TESTING PIPELINE: PHARMACOKINETICS AND PHARMACODYNAMICS OF PROPHYLACTIC TREATMENT WITH LEVETIRACETAM IN THE 5XFAD MOUSE MODEL OF ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P684, doi. 10.1016/j.jalz.2018.06.729
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- Publication type:
- Article
P1‐130: MODEL‐AD: CHARACTERIZATION OF FAMILIAL AD MODELS (5XFAD, APP/PS1, HTAU, 3XTG‐AD).
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P321, doi. 10.1016/j.jalz.2018.06.133
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- Publication type:
- Article
P1‐131: MODEL‐AD: LATE‐ONSET ALZHEIMER'S DISEASE MODELS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P321, doi. 10.1016/j.jalz.2018.06.134
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- Publication type:
- Article
P1‐134: PRESERVING AND PROTECTING THE CEREBROVASCULATURE IN MOUSE MODELS WITH A GENETIC PREDISPOSITION FOR DEMENTIA.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P323, doi. 10.1016/j.jalz.2018.06.137
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- Publication type:
- Article
NOVEL CANDIDATE LOCI FOR LATE-ONSET ALZHEIMER’S DISEASE FROM BAYESIAN MIXED MODELING OF WHOLE-GENOME AND WHOLE-EXOME SEQUENCING.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1490, doi. 10.1016/j.jalz.2017.07.574
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- Publication type:
- Article
MODEL ORGANISM DEVELOPMENT AND EVALUATION FOR LATE-ONSET ALZHEIMER’S DISEASE: MODEL-AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1280, doi. 10.1016/j.jalz.2017.06.1925
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- Publication type:
- Article
Early detection of β-amyloid aggregation in in vivo and in vitro models of Alzheimer's disease
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- 2010
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- Publication type:
- Abstract
P1-094: Mouse resources for the study of neurodegenerative diseases
- Published in:
- 2008
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- Publication type:
- Abstract
P1-083: The Alzheimer’s disease mouse model resource
- Published in:
- 2006
- By:
- Publication type:
- Abstract
P1-083: The Alzheimer’s disease mouse model resource
- Published in:
- 2006
- By:
- Publication type:
- Abstract
The 677C > T variant in methylenetetrahydrofolate reductase causes morphological and functional cerebrovascular deficits in mice.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 2022, v. 42, n. 12, p. 2333, doi. 10.1177/0271678X221122644
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- Publication type:
- Article
Plcg2<sup>M28L</sup> Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.886575
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- Publication type:
- Article
The APOE <sup>ε3/ε4</sup> Genotype Drives Distinct Gene Signatures in the Cortex of Young Mice.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.838436
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- Publication type:
- Article
Corrigendum: Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2<sup>*</sup>R47H.
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- 2022
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- Publication type:
- Correction Notice
Decreased glucocerebrosidase activity and substrate accumulation of glycosphingolipids in a novel GBA1 D409V knock-in mouse model.
- Published in:
- PLoS ONE, 2021, v. 16, n. 6, p. 1, doi. 10.1371/journal.pone.0252325
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- Publication type:
- Article
Neuregulin-beta induces expression of an NMDA-receptor subunit.
- Published in:
- Nature, 1997, v. 390, n. 6661, p. 691, doi. 10.1038/37795
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- Publication type:
- Article
Uncovering Disease Mechanisms in a Novel Mouse Model Expressing Humanized APOEε4 and Trem2*R47H.
- Published in:
- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.735524
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- Publication type:
- Article
A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00412-5
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- Publication type:
- Article