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Nanocell-mediated delivery of miR-34a counteracts temozolomide resistance in glioblastoma.
- Published in:
- Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00293-4
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- Publication type:
- Article
Inhibition of phosphatidylinositol 3-kinase by PX-866 suppresses temozolomide-induced autophagy and promotes apoptosis in glioblastoma cells.
- Published in:
- Molecular Medicine, 2019, v. 25, n. 1, p. 1, doi. 10.1186/s10020-019-0116-z
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- Article
Pathogenic Germ Line Variants in a Patient With Severe Toxicity From Breast Radiotherapy.
- Published in:
- 2019
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- Publication type:
- journal article
The novel BET inhibitor UM-002 reduces glioblastoma cell proliferation and invasion.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02584-6
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- Publication type:
- Article
Quantifying Glioblastoma Drug Response Dynamics Incorporating Treatment Sensitivity and Blood Brain Barrier Penetrance From Experimental Data.
- Published in:
- Frontiers in Physiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphys.2020.00830
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- Publication type:
- Article
IL-13Rα2 Status Predicts GB-13 (IL13.E13K-PE4E) Efficacy in High-Grade Glioma.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 5, p. 922, doi. 10.3390/pharmaceutics14050922
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- Publication type:
- Article
Addressing BBB Heterogeneity: A New Paradigm for Drug Delivery to Brain Tumors.
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- Pharmaceutics, 2020, v. 12, n. 12, p. 1205, doi. 10.3390/pharmaceutics12121205
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- Publication type:
- Article
Glycan Node Analysis Detects Varying Glycosaminoglycan Levels in Melanoma-Derived Extracellular Vesicles.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 8506, doi. 10.3390/ijms24108506
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- Publication type:
- Article
Alkylpurine--DNA--N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 1, p. 253, doi. 10.1172/JCI59334
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- Publication type:
- Article
Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.
- Published in:
- 2011
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- Publication type:
- journal article
Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells.
- Published in:
- Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02258-z
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- Publication type:
- Article
Blockade of tumor cell-intrinsic PD-L1 signaling enhances AURKA-targeted therapy in triple negative breast cancer.
- Published in:
- Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1384277
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- Publication type:
- Article
Peak learning of mass spectrometry imaging data using artificial neural networks.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25744-8
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- Publication type:
- Article
How Much is Enough? Impact of Efflux Transporters on Drug delivery Leading to Efficacy in the Treatment of Brain Tumors.
- Published in:
- Pharmaceutical Research, 2023, v. 40, n. 11, p. 2731, doi. 10.1007/s11095-023-03574-1
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- Publication type:
- Article
Barriers to Effective Drug Treatment for Brain Metastases: A Multifactorial Problem in the Delivery of Precision Medicine.
- Published in:
- Pharmaceutical Research, 2018, v. 35, n. 9, p. 1, doi. 10.1007/s11095-018-2455-9
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- Publication type:
- Article
Using fluorodeoxythymidine to monitor anti-EGFR inhibitor therapy in squamous cell carcinoma xenografts.
- Published in:
- Head & Neck, 2008, v. 30, n. 6, p. 790, doi. 10.1002/hed.20770
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- Article
Oral tongue cancer in young adults less than 40 years of age: Rationale for aggressive therapy.
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- Head & Neck, 1994, v. 16, n. 2, p. 107, doi. 10.1002/hed.2880160202
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- Publication type:
- Article
Brain metastases-derived extracellular vesicles induce binding and aggregation of low-density lipoprotein.
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- Journal of Nanobiotechnology, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12951-020-00722-2
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- Publication type:
- Article
Semaphorin 3A mediated brain tumor stem cell proliferation and invasion in EGFRviii mutant gliomas.
- Published in:
- 2020
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- Publication type:
- journal article
massNet: integrated processing and classification of spatially resolved mass spectrometry data using deep learning for rapid tumor delineation.
- Published in:
- Bioinformatics, 2022, v. 38, n. 7, p. 2015, doi. 10.1093/bioinformatics/btac032
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- Publication type:
- Article
Network Modeling Identifies Patient-specific Pathways in Glioblastoma.
- Published in:
- Scientific Reports, 2016, p. 28668, doi. 10.1038/srep28668
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- Publication type:
- Article
Effective Treatment of Established GL261 Murine Gliomas through Picornavirus Vaccination-Enhanced Tumor Antigen-Specific CD8+ T Cell Responses.
- Published in:
- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125565
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- Publication type:
- Article
Peptide Carrier-Mediated Non-Covalent Delivery of Unmodified Cisplatin, Methotrexate and Other Agents via Intravenous Route to the Brain.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097655
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- Publication type:
- Article
Targeting Src Family Kinases Inhibits Bevacizumab-Induced Glioma Cell Invasion.
- Published in:
- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056505
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- Publication type:
- Article
Misregulated E-Cadherin Expression Associated with an Aggressive Brain Tumor Phenotype.
- Published in:
- PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013665
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- Publication type:
- Article
Incorporation of Biomarker Assessment in Novel Clinical Trial Designs: Personalizing Brain Tumor Treatments.
- Published in:
- Current Oncology Reports, 2011, v. 13, n. 1, p. 42, doi. 10.1007/s11912-010-0144-x
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- Publication type:
- Article
Synthetic and systems biology principles in the design of programmable oncolytic virus immunotherapies for glioblastoma.
- Published in:
- Neurosurgical Focus, 2021, v. 50, n. 2, p. 1, doi. 10.3171/2020.12.FOCUS20855
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- Publication type:
- Article
Evaluating infusate parameters for direct drug delivery to the brainstem: a comparative study of convection-enhanced delivery versus osmotic pump delivery.
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- Neurosurgical Focus, 2020, v. 48, n. 1, p. 1, doi. 10.3171/2019.10.FOCUS19703
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- Publication type:
- Article
Drug and disease signature integration identifies synergistic combinations in glioblastoma.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07659-z
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- Publication type:
- Article
Modeling Therapy-Driven Evolution of Glioblastoma with Patient-Derived Xenografts.
- Published in:
- Cancers, 2022, v. 14, n. 22, p. 5494, doi. 10.3390/cancers14225494
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- Publication type:
- Article
Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies.
- Published in:
- Cancers, 2020, v. 12, n. 12, p. 3531, doi. 10.3390/cancers12123531
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- Publication type:
- Article
NOTCH3 expression is linked to breast cancer seeding and distant metastasis.
- Published in:
- 2018
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- Publication type:
- journal article
Real-Time Methylation-Specific Polymerase Chain Reaction for MGMT Promoter Methylation Clinical Testing in Glioblastoma: An Alternative Detection Method for a Heterogeneous Process.
- Published in:
- 2017
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- Publication type:
- journal article
Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation.
- Published in:
- Investigational New Drugs, 2014, v. 32, n. 4, p. 604, doi. 10.1007/s10637-014-0084-7
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- Publication type:
- Article
Phase I study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors.
- Published in:
- Investigational New Drugs, 2012, v. 30, n. 5, p. 1934, doi. 10.1007/s10637-011-9742-1
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- Publication type:
- Article
Targeting Glioblastoma Tumor Hyaluronan to Enhance Therapeutic Interventions that Regulate Metabolic Cell Properties.
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- Advanced Therapeutics, 2024, v. 7, n. 10, p. 1, doi. 10.1002/adtp.202400041
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- Publication type:
- Article
Perivascular Stromal Cells Instruct Glioblastoma Invasion, Proliferation, and Therapeutic Response within an Engineered Brain Perivascular Niche Model.
- Published in:
- Advanced Science, 2022, v. 9, n. 31, p. 1, doi. 10.1002/advs.202201888
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- Publication type:
- Article
Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63494-7
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- Publication type:
- Article
WWP2 is an E3 ubiquitin ligase for PTEN.
- Published in:
- Nature Cell Biology, 2011, v. 13, n. 6, p. 730, doi. 10.1038/ncb2240
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- Publication type:
- Article
Changes in the vasculature of human brain tumors: Implications for treatment.
- Published in:
- Neuro-Oncology, 2021, v. 23, n. 12, p. 1995, doi. 10.1093/neuonc/noab220
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- Publication type:
- Article
Experimental design of preclinical experiments: number of PDX lines vs subsampling within PDX lines.
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- Neuro-Oncology, 2021, v. 23, n. 12, p. 2066, doi. 10.1093/neuonc/noab137
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- Publication type:
- Article
Baseline requirements for novel agents being considered for phase II/III brain cancer efficacy trials: conclusions from the Adult Brain Tumor Consortium's first workshop on CNS drug delivery.
- Published in:
- Neuro-Oncology, 2020, v. 22, n. 10, p. 1422, doi. 10.1093/neuonc/noaa142
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- Publication type:
- Article
Comments on: "Synergistic activity of mTORC1/2 kinase and MEK inhibitors suppresses pediatric low-grade glioma tumorigenicity and vascularity".
- Published in:
- Neuro-Oncology, 2020, v. 22, n. 9, p. 1404, doi. 10.1093/neuonc/noaa112
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- Publication type:
- Article
Patient-derived xenografts of central nervous system metastasis reveal expansion of aggressive minor clones.
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- Neuro-Oncology, 2020, v. 22, n. 1, p. 70, doi. 10.1093/neuonc/noz137
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- Publication type:
- Article
Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma.
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- Neuro-Oncology, 2019, v. 21, n. 12, p. 1529, doi. 10.1093/neuonc/noz127
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- Publication type:
- Article
The medical necessity of advanced molecular testing in the diagnosis and treatment of brain tumor patients.
- Published in:
- Neuro-Oncology, 2019, v. 21, n. 12, p. 1498, doi. 10.1093/neuonc/noz119
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- Publication type:
- Article
Xenograft-based, platform-independent gene signatures to predict response to alkylating chemotherapy, radiation, and combination therapy for glioblastoma.
- Published in:
- Neuro-Oncology, 2019, v. 21, n. 9, p. 1141, doi. 10.1093/neuonc/noz090
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- Publication type:
- Article
THER-22. BROMODOMAIN INHIBITORS INDUCE DOWNREGULATION OF DNA DAMAGE REPAIR PATHWAYS AND OFFER NOVEL SYNERGISTIC COMBINATIONS WITH ENHANCED SAFETY PROFILES FOR THE TREATMENT OF MEDULLOBLASTOMA AND GLIOBLASTOMA.
- Published in:
- Neuro-Oncology, 2019, v. 21, p. ii118, doi. 10.1093/neuonc/noz036.227
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- Publication type:
- Article
TMOD-11. IMAGING BASED INVASION METRIC PREDICTIVE OF RESPONSE TO ABT414 IN ORTHOTOPIC EGFRviii AMPLIFIED PATIENT DERIVED XENOGRAFTS.
- Published in:
- Neuro-Oncology, 2018, v. 20, p. vi270, doi. 10.1093/neuonc/noy148.1124
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- Publication type:
- Article
TMIC-36. LOCAL TISSUE BIOMARKERS OF RESPONSE TO THERAPY FOR GLIOBLASTOMA.
- Published in:
- Neuro-Oncology, 2018, v. 20, p. vi264, doi. 10.1093/neuonc/noy148.1095
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- Publication type:
- Article