Found: 30
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Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses.
- Published in:
- Journal of Pathology, 2015, v. 236, n. 4, p. 421, doi. 10.1002/path.4538
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- Publication type:
- Article
Editorial: Premature Aging and Senescence in Renal Fibrosis.
- Published in:
- 2021
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- Publication type:
- Editorial
Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression.
- Published in:
- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022896
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- Publication type:
- Article
SERPINE1 (PAI-1) is deposited into keratinocyte migration “trails” and required for optimal monolayer wound repair.
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- Archives of Dermatological Research, 2008, v. 300, n. 6, p. 303, doi. 10.1007/s00403-008-0845-2
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- Publication type:
- Article
The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1.
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- Biomolecules (2218-273X), 2019, v. 9, n. 8, p. 341, doi. 10.3390/biom9080341
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- Publication type:
- Article
Emerging Role of Hippo-YAP (Yes-Associated Protein)/TAZ (Transcriptional Coactivator with PDZ-Binding Motif) Pathway Dysregulation in Renal Cell Carcinoma Progression.
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- Cancers, 2024, v. 16, n. 15, p. 2758, doi. 10.3390/cancers16152758
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- Publication type:
- Article
Downstream Targets of VHL/HIF-α Signaling in Renal Clear Cell Carcinoma Progression: Mechanisms and Therapeutic Relevance.
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- Cancers, 2023, v. 15, n. 4, p. 1316, doi. 10.3390/cancers15041316
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- Publication type:
- Article
Cancer-Associated Fibroblasts: Mechanisms of Tumor Progression and Novel Therapeutic Targets.
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- Cancers, 2022, v. 14, n. 5, p. 1231, doi. 10.3390/cancers14051231
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- Publication type:
- Article
Heat Shock Protein 27, a Novel Downstream Target of Collagen Type XI alpha 1, Synergizes with Fatty Acid Oxidation to Confer Cisplatin Resistance in Ovarian Cancer Cells.
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- Cancers, 2021, v. 13, n. 19, p. 4855, doi. 10.3390/cancers13194855
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- Publication type:
- Article
Deregulation of Negative Controls on TGF-β1 Signaling in Tumor Progression.
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- Cancers, 2018, v. 10, n. 6, p. 159, doi. 10.3390/cancers10060159
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- Publication type:
- Article
Emerging role of tumor suppressor p53 in acute and chronic kidney diseases.
- Published in:
- Cellular & Molecular Life Sciences, 2022, v. 79, n. 9, p. 1, doi. 10.1007/s00018-022-04505-w
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- Publication type:
- Article
PAI-1 induction during kidney injury promotes fibrotic epithelial dysfunction via deregulation of klotho, p53, and TGF-_1-receptor signaling.
- Published in:
- FASEB Journal, 2021, v. 35, n. 7, p. 1, doi. 10.1096/fj.202002652RR
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- Publication type:
- Article
Protein phosphatase Mg<sup>2+</sup>/Mn<sup>2+</sup> dependent‐1A and PTEN deregulation in renal fibrosis: Novel mechanisms and co‐dependency of expression.
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- FASEB Journal, 2020, v. 34, n. 2, p. 2641, doi. 10.1096/fj.201902015RR
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- Publication type:
- Article
TGF-β1-p53 cooperativity regulates a profibrotic genomic program in the kidney: molecular mechanisms and clinical implications.
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- FASEB Journal, 2019, v. 33, n. 10, p. 10596, doi. 10.1096/fj.201900943R
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- Publication type:
- Article
Rac-GTPase promotes fibrotic TGF-β1 signaling and chronic kidney disease via EGFR, p53, and Hippo/YAP/TAZ pathways.
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- FASEB Journal, 2019, v. 33, n. 9, p. 9797, doi. 10.1096/fj.201802489RR
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- Publication type:
- Article
Deregulation of Hippo-TAZ pathway during renal injury confers a fibrotic maladaptive phenotype.
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- FASEB Journal, 2018, v. 32, n. 5, p. 2644, doi. 10.1096/fj.201700722R
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- Publication type:
- Article
Loss of expression of protein phosphatase magnesium-dependent 1A during kidney injury promotes fibrotic maladaptive repair.
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- FASEB Journal, 2016, v. 30, n. 10, p. 3308, doi. 10.1096/fj.201500105R
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- Publication type:
- Article
Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses.
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- FASEB Journal, 2015, v. 29, n. 4, p. 1258, doi. 10.1096/fj.14-262527
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- Publication type:
- Article
PAI-1 Mediates the TGF-β1+EGF-Induced “Scatter” Response in Transformed Human Keratinocytes.
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- Journal of Investigative Dermatology, 2010, v. 130, n. 9, p. 2179, doi. 10.1038/jid.2010.106
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- Publication type:
- Article
SERPINE1 (PAI-1) Is a Prominent Member of the Early G<sub>0</sub> → G<sub>1</sub> Transition “Wound Repair” Transcriptome in p53 Mutant Human Keratinocytes.
- Published in:
- 2008
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- Publication type:
- Letter
Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-1-stimulated smooth muscle cells is pp60c-src/MEK-dependent.
- Published in:
- Journal of Cellular Physiology, 2005, v. 204, n. 1, p. 236, doi. 10.1002/jcp.20279
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- Publication type:
- Article
pp60<sup>c-src</sup> mediates ERK activation/nuclear localization and PAI-1 gene expression in response to cellular deformation.
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- Journal of Cellular Physiology, 2003, v. 195, n. 3, p. 411, doi. 10.1002/jcp.10247
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- Publication type:
- Article
TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis.
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- Cell & Tissue Research, 2012, v. 347, n. 1, p. 117, doi. 10.1007/s00441-011-1181-y
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- Publication type:
- Article
SERPINE1: Role in Cholangiocarcinoma Progression and a Therapeutic Target in the Desmoplastic Microenvironment.
- Published in:
- Cells (2073-4409), 2024, v. 13, n. 10, p. 796, doi. 10.3390/cells13100796
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- Publication type:
- Article
Mineralocorticoid Receptor-Associated Mechanisms in Diabetic Kidney Disease and Clinical Significance of Mineralocorticoid Receptor Antagonists.
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- American Journal of Nephrology, 2023, v. 54, n. 1/2, p. 50, doi. 10.1159/000528783
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- Publication type:
- Article
Negative regulators of TGF-β1 signaling in renal fibrosis; pathological mechanisms and novel therapeutic opportunities.
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- Clinical Science, 2021, v. 135, n. 2, p. 275, doi. 10.1042/CS20201213
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- Publication type:
- Article
PAI-1 Regulates the Invasive Phenotype in Human Cutaneous Squamous Cell Carcinoma.
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- Journal of Oncology, 2009, p. 1, doi. 10.1155/2009/963209
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- Publication type:
- Article
TGF-β1-Induced Expression of the Poor Prognosis SERPINE1/PAI-1 Gene Requires EGFR Signaling: A New Target for Anti-EGFR Therapy.
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- Journal of Oncology, 2009, p. 1, doi. 10.1155/2009/342391
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- Publication type:
- Article
Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.
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- Aging Cell, 2021, v. 20, n. 10, p. 1, doi. 10.1111/acel.13472
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- Publication type:
- Article
PAI-1: An Integrator of Cell Signaling and Migration.
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- International Journal of Cell Biology, 2011, v. 2011, p. 1, doi. 10.1155/2011/562481
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- Publication type:
- Article