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A769662 Inhibits Insulin-Stimulated Akt Activation in Human Macrovascular Endothelial Cells Independent of AMP-Activated Protein Kinase.
Published in:
International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3886, doi. 10.3390/ijms19123886
By:
- Strembitska, Anastasiya;
- Mancini, Sarah J.;
- Gamwell, Jonathan M.;
- Palmer, Timothy M.;
- Baillie, George S.;
- Salt, Ian P.
Publication type:
Article
Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965.
Published in:
Biochemical Journal, 2021, v. 478, n. 15, p. 2977, doi. 10.1042/BCJ20210284
By:
- Ahwazi, Danial;
- Neopane, Katyayanee;
- Markby, Greg R.;
- Kopietz, Franziska;
- Ovens, Ashley J.;
- Dall, Morten;
- Hassing, Anna S.;
- Gräsle, Pamina;
- Alshuweishi, Yazeed;
- Treebak, Jonas T.;
- Salt, Ian P.;
- Göransson, Olga;
- Zeqiraj, Elton;
- Scott, John W.;
- Sakamoto, Kei
Publication type:
Article
A-769662 inhibits adipocyte glucose uptake in an AMPK-independent manner.
Published in:
Biochemical Journal, 2021, v. 478, n. 3, p. 633, doi. 10.1042/BCJ20200659
By:
- Kopietz, Franziska;
- Alshuweishi, Yazeed;
- Bijland, Silvia;
- Alghamdi, Fatmah;
- Degerman, Eva;
- Sakamoto, Kei;
- Salt, Ian P.;
- Göransson, Olga
Publication type:
Article
AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis.
Published in:
Biochemical Journal, 2019, v. 476, n. 12, p. 1725, doi. 10.1042/BCJ20180714
By:
- Katwan, Omar J.;
- Alghamdi, Fatmah;
- Almabrouk, Tarek A.;
- Mancini, Sarah J.;
- Kennedy, Simon;
- Oakhill, Jonathan S.;
- Scott, John W.;
- Salt, Ian P.
Publication type:
Article
Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487.
Published in:
Biochemical Journal, 2016, v. 473, n. 24, p. 4681, doi. 10.1042/BCJ20160211
By:
- Heathcote, Helen R.;
- Mancini, Sarah J.;
- Strembitska, Anastasiya;
- Jamal, Kunzah;
- Reihill, James A.;
- Palmer, Timothy M.;
- Gould, Gwyn W.;
- Salt, Ian P.
Publication type:
Article
Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling.
Published in:
Science Signaling, 2016, v. 9, n. 453, p. 1, doi. 10.1126/scisignal.aaf8566
By:
- Rutherford, Claire;
- Speirs, Claire;
- Williams, Jamie J. L.;
- Ewart, Marie-Ann;
- Mancini, Sarah J.;
- Hawley, Simon A.;
- Delles, Christian;
- Viollet, Benoit;
- Costa-Pereira, Ana P.;
- Baillie, George S.;
- Salt, Ian P.;
- Palmer, Timothy M.
Publication type:
Article
Fat Oxidation, Fitness and Skeletal Muscle Expression of Oxidative/Lipid Metabolism Genes in South Asians: Implications for Insulin Resistance?
Published in:
PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0014197
By:
- Hall, Lesley M. L.;
- Moran, Colin N.;
- Milne, Gillian R.;
- Wilson, John;
- MacFarlane, Niall G.;
- Forouhi, Nita G.;
- Hariharan, Narayanan;
- Salt, Ian P.;
- Sattar, Naveed;
- Gill, Jason M. R.
Publication type:
Article
Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation.
Published in:
Clinical Science, 2013, v. 124, n. 8, p. 491, doi. 10.1042/CS20120536
By:
- BIJLAND, Silvia;
- MANCINI, Sarah J.;
- SALT, Ian P.
Publication type:
Article
Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes.
Published in:
Clinical Science, 2013, v. 124, n. 6, p. 403, doi. 10.1042/CS20120239
By:
- MACKENZIE, Ruth M.;
- SALT, Ian P.;
- MILLER, William H.;
- LOGAN, Angela;
- IBRAHIM, Hagar A.;
- DEGASPERI, Andrea;
- DYMOTT, Jane A.;
- HAMILTON, Carlene A.;
- MURPHY, Michael P.;
- DELLES, Christian;
- DOMINICZAK, Anna F.
Publication type:
Article
Metformin again? Atheroprotection mediated by macrophage AMPK and ATF1.
Published in:
Cardiovascular Research, 2021, v. 117, n. 5, p. 1233, doi. 10.1093/cvr/cvab065
By:
- Salt, Ian P;
- Nunes, Julia R C;
- Fullerton, Morgan D
Publication type:
Article
The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho‐physiological background.
Published in:
FASEB Journal, 2023, v. 37, n. 11, p. 1, doi. 10.1096/fj.202300960RR
By:
- Irshad, Zehra;
- Lund, Jenny;
- Sillars, Anne;
- Løvsletten, Nils Gunnar;
- Gharanei, Seley;
- Salt, Ian P.;
- Freeman, Dilys J.;
- Gill, Jason M. R.;
- Thoresen, G. Hege;
- Rustan, Arild C.;
- Zammit, Victor A.
Publication type:
Article
Molecular mechanisms regulating perivascular adipose tissue - potential pharmacological targets?
Published in:
2017
By:
- Kennedy, Simon;
- Salt, Ian P
Publication type:
Editorial
Deletion of AMPKα1 attenuates the anticontractile effect of perivascular adipose tissue (PVAT) and reduces adiponectin release.
Published in:
2017
By:
- Almabrouk, Tarek A M;
- Ugusman, Azizah B;
- Katwan, Omar J;
- Salt, Ian P;
- Kennedy, Simon
Publication type:
journal article
Skeletal muscle of stroke-prone spontaneously hypertensive rats exhibits reduced insulin-stimulated glucose transport and elevated levels of caveolin and flotillin.
Published in:
2001
By:
- James, Declan J.;
- Cairns, Fiona;
- Salt, Ian P.;
- Murphy, Gregory J.;
- Dominiczak, Anna F.;
- Connell, John M.C.;
- Gould, Gwyn W.;
- James, D J;
- Cairns, F;
- Salt, I P;
- Murphy, G J;
- Dominiczak, A F;
- Connell, J M;
- Gould, G W
Publication type:
journal article
Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase.
Published in:
2000
By:
- Fryer, Lee G.D.;
- Hajduch, Eric;
- Rencurel, Frank;
- Salt, Ian P.;
- Fryer, L G;
- Hajduch, E;
- Rencurel, F;
- Salt, I P;
- Hundal, H S;
- Hardie, D G;
- Carling, D
Publication type:
journal article
5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes.
Published in:
2000
By:
- Salt, Ian P.;
- Connell, John M. C.;
- Gould, Gwyn W.;
- Salt, I P;
- Connell, J M;
- Gould, G W
Publication type:
journal article
5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase.
Published in:
2000
By:
- Lochhead, Pamela A.;
- Salt, Ian P.;
- Walker, Kay S.;
- Hardie, D. Grahame;
- Sutherland, Calum;
- Lochhead, P A;
- Salt, I P;
- Walker, K S;
- Hardie, D G;
- Sutherland, C
Publication type:
journal article
Lin28A induces energetic switching to glycolytic metabolism in human embryonic kidney cells.
Published in:
Stem Cell Research & Therapy, 2016, p. 1, doi. 10.1186/s13287-016-0323-2
By:
- Docherty, Craig K.;
- Salt, Ian P.;
- Mercer, John R.
Publication type:
Article
Nutrient regulation of inflammatory signalling in obesity and vascular disease.
Published in:
Clinical Science, 2021, v. 135, n. 13, p. 1563, doi. 10.1042/CS20190768
By:
- Palmer, Timothy M.;
- Salt, Ian P.
Publication type:
Article
The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels.
Published in:
2016
By:
- Hawley, Simon A.;
- Ford, Rebecca J.;
- Smith, Brennan K.;
- Gowans, Graeme J.;
- Mancini, Sarah J.;
- Pitt, Ryan D.;
- Day, Emily A.;
- Salt, Ian P.;
- Steinberg, Gregory R.;
- Hardie, D. Grahame
Publication type:
journal article

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