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EV20/NMS-P945, a Novel Thienoindole Based Antibody-Drug Conjugate Targeting HER-3 for Solid Tumors.
Published in:
Pharmaceutics, 2021, v. 13, n. 4, p. 483, doi. 10.3390/pharmaceutics13040483
By:
- Capone, Emily;
- Lattanzio, Rossano;
- Gasparri, Fabio;
- Orsini, Paolo;
- Rossi, Cosmo;
- Iacobelli, Valentina;
- De Laurenzi, Vincenzo;
- Natali, Pier Giorgio;
- Valsasina, Barbara;
- Iacobelli, Stefano;
- Sala, Gianluca;
- Yallapu, Murali Mohan
Publication type:
Article
Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy.
Published in:
Pharmaceutics, 2020, v. 12, n. 10, p. 992, doi. 10.3390/pharmaceutics12100992
By:
- Falvo, Elisabetta;
- Arcovito, Alessandro;
- Conti, Giamaica;
- Cipolla, Giuseppe;
- Pitea, Martina;
- Morea, Veronica;
- Damiani, Verena;
- Sala, Gianluca;
- Fracasso, Giulio;
- Ceci, Pierpaolo
Publication type:
Article
HER3 targeting with an antibody‐drug conjugate bypasses resistance to anti‐HER2 therapies.
Published in:
EMBO Molecular Medicine, 2020, v. 12, n. 5, p. 1, doi. 10.15252/emmm.201911498
By:
- Gandullo‐Sánchez, Lucía;
- Capone, Emily;
- Ocaña, Alberto;
- Iacobelli, Stefano;
- Sala, Gianluca;
- Pandiella, Atanasio
Publication type:
Article
High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2021, v. 40, n. 1, p. 1, doi. 10.1186/s13046-021-01851-8
By:
- Falvo, Elisabetta;
- Damiani, Verena;
- Conti, Giamaica;
- Boschi, Federico;
- Messana, Katia;
- Giacomini, Patrizio;
- Milella, Michele;
- De Laurenzi, Vincenzo;
- Morea, Veronica;
- Sala, Gianluca;
- Fracasso, Giulio;
- Ceci, Pierpaolo
Publication type:
Article
Functional and prognostic significance of the genomic amplification of frizzled 6 ( FZD6) in breast cancer.
Published in:
Journal of Pathology, 2017, v. 241, n. 3, p. 350, doi. 10.1002/path.4841
By:
- Corda, Gabriele;
- Sala, Gianluca;
- Lattanzio, Rossano;
- Iezzi, Manuela;
- Sallese, Michele;
- Fragassi, Giorgia;
- Lamolinara, Alessia;
- Mirza, Hasan;
- Barcaroli, Daniela;
- Ermler, Sibylle;
- Silva, Elisabete;
- Yasaei, Hemad;
- Newbold, Robert F;
- Vagnarelli, Paola;
- Mottolese, Marcella;
- Natali, Pier Giorgio;
- Perracchio, Letizia;
- Quist, Jelmar;
- Grigoriadis, Anita;
- Marra, Pierfrancesco
Publication type:
Article
Antibody-Drug Conjugates: The New Frontier of Chemotherapy.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5510, doi. 10.3390/ijms21155510
By:
- Ponziani, Sara;
- Di Vittorio, Giulia;
- Pitari, Giuseppina;
- Cimini, Anna Maria;
- Ardini, Matteo;
- Gentile, Roberta;
- Iacobelli, Stefano;
- Sala, Gianluca;
- Capone, Emily;
- Flavell, David J.;
- Ippoliti, Rodolfo;
- Giansanti, Francesco
Publication type:
Article
Therapeutic Efficacy of the Novel Stimuli-Sensitive Nano-Ferritins Containing Doxorubicin in a Head and Neck Cancer Model.
Published in:
International Journal of Molecular Sciences, 2017, v. 18, n. 7, p. 1555, doi. 10.3390/ijms18071555
By:
- Damiani, Verena;
- Falvo, Elisabetta;
- Fracasso, Giulio;
- Federici, Luca;
- Pitea, Martina;
- De Laurenzi, Vincenzo;
- Sala, Gianluca;
- Ceci, Pierpaolo
Publication type:
Article
Concerted BAG3 and SIRPα blockade impairs pancreatic tumor growth.
Published in:
Cell Death Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41420-022-00817-9
By:
- De Marco, Margot;
- Gauttier, Vanessa;
- Pengam, Sabrina;
- Mary, Caroline;
- Ranieri, Bianca;
- Basile, Anna;
- Festa, Michela;
- Falco, Antonia;
- Reppucci, Francesca;
- Cammarota, Anna Lisa;
- Acernese, Fausto;
- De Laurenzi, Vincenzo;
- Sala, Gianluca;
- Brongo, Sergio;
- Miyasaka, Masayuki;
- Shalapour, Shabnam;
- Vanhove, Bernard;
- Poirier, Nicolas;
- Iaccarino, Roberta;
- Karin, Michael
Publication type:
Article
Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1308-7
By:
- Adamska, Aleksandra;
- Domenichini, Alice;
- Capone, Emily;
- Damiani, Verena;
- Akkaya, Begum Gokcen;
- Linton, Kenneth J.;
- Di Sebastiano, Pierluigi;
- Chen, Xi;
- Keeton, Adam B.;
- Ramirez-Alcantara, Veronica;
- Maxuitenko, Yulia;
- Piazza, Gary A.;
- De Laurenzi, Vincenzo;
- Sala, Gianluca;
- Falasca, Marco
Publication type:
Article
Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2019, v. 38, n. 1, p. N.PAG, doi. 10.1186/s13046-019-1191-2
By:
- Emmanouilidi, Aikaterini;
- Fyffe, Chanse A.;
- Ferro, Riccardo;
- Edling, Charlotte E.;
- Capone, Emily;
- Sestito, Simona;
- Rapposelli, Simona;
- Lattanzio, Rossano;
- Iacobelli, Stefano;
- Sala, Gianluca;
- Maffucci, Tania;
- Falasca, Marco
Publication type:
Article
Cost-sensitive rainfall thresholds for shallow landslides.
Published in:
Landslides, 2021, v. 18, n. 9, p. 2979, doi. 10.1007/s10346-021-01707-4
By:
- Sala, Gianluca;
- Lanfranconi, Camilla;
- Frattini, Paolo;
- Rusconi, Giulia;
- Crosta, Giovanni B.
Publication type:
Article
HER-3 surface expression increases in advanced colorectal cancer representing a potential therapeutic target.
Published in:
Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01692-8
By:
- Capone, Emily;
- Tryggvason, Thordur;
- Cela, Ilaria;
- Dufrusine, Beatrice;
- Pinti, Morena;
- Del Pizzo, Francesco;
- Gunnarsdottir, Helga Sigrun;
- Grottola, Tommaso;
- De Laurenzi, Vincenzo;
- Iacobelli, Stefano;
- Lattanzio, Rossano;
- Sala, Gianluca
Publication type:
Article
A Phosphoinositide 3-Kinase/Phospholipase Cgamma1 Pathway Regulates Fibroblast Growth Factor-Induced Capillary Tube Formation.
Published in:
PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008285
By:
- Maffucci, Tania;
- Raimondi, Claudio;
- Abu-Hayyeh, Shadi;
- Dominguez, Veronica;
- Sala, Gianluca;
- Zachary, Ian;
- Falasca, Marco
Publication type:
Article
Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin.
Published in:
Oncogene, 2005, v. 24, n. 28, p. 4540, doi. 10.1038/sj.onc.1208658
By:
- Anastasi, Sergio;
- Sala, Gianluca;
- Huiping, Chen;
- Caprini, Elisabetta;
- Russo, Giandomenico;
- Iacovelli, Stefano;
- Lucini, Fabiana;
- Ingvarsson, Sigurdur;
- Segatto, Oreste
Publication type:
Article
Feedback inhibition by RALT controls signal output by the ErbB network.
Published in:
Oncogene, 2003, v. 22, n. 27, p. 4221, doi. 10.1038/sj.onc.1206516
By:
- Anastasi, Sergio;
- Fiorentino, Loredana;
- Fiorini, Monia;
- Fraioli, Rocco;
- Sala, Gianluca;
- Castellani, L;
- Alema, Stefano;
- Alimandi, Maurizio;
- Segatto, Oreste
Publication type:
Article
Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control.
Published in:
Oncogene, 2002, v. 21, n. 42, p. 6530, doi. 10.1038/sj.onc.1205823
By:
- Fiorini, Monia;
- Ballaro, Costanza;
- Sala, Gianluca;
- Falcone, Germana;
- Alema, Stefano;
- Segatto, Oreste
Publication type:
Article
Therapeutic Potential of Antibody-Drug Conjugate-Based Therapy in Head and Neck Cancer: A Systematic Review.
Published in:
Cancers, 2021, v. 13, n. 13, p. 3126, doi. 10.3390/cancers13133126
By:
- Perrotti, Vittoria;
- Caponio, Vito Carlo Alberto;
- Mascitti, Marco;
- Lo Muzio, Lorenzo;
- Piattelli, Adriano;
- Rubini, Corrado;
- Capone, Emily;
- Sala, Gianluca
Publication type:
Article
Dual PDK1/Aurora Kinase A Inhibitors Reduce Pancreatic Cancer Cell Proliferation and Colony Formation.
Published in:
Cancers, 2019, v. 11, n. 11, p. 1695, doi. 10.3390/cancers11111695
By:
- Casari, Ilaria;
- Domenichini, Alice;
- Sestito, Simona;
- Capone, Emily;
- Sala, Gianluca;
- Rapposelli, Simona;
- Falasca, Marco
Publication type:
Article
The mitotic checkpoint kinase BUB1 is a direct and actionable target of MYB in adenoid cystic carcinoma.
Published in:
FEBS Letters, 2024, v. 598, n. 2, p. 252, doi. 10.1002/1873-3468.14786
By:
- Cicirò, Ylenia;
- Ragusa, Denise;
- Nevado, Paloma Tejera;
- Lattanzio, Rossano;
- Sala, Gianluca;
- DesRochers, Tessa;
- Millard, Melissa;
- Andersson, Mattias K.;
- Stenman, Göran;
- Sala, Arturo
Publication type:
Article
Extracellular LGALS3BP: a potential disease marker and actionable target for antibody–drug conjugate therapy in glioblastoma.
Published in:
Molecular Oncology, 2023, v. 17, n. 8, p. 1460, doi. 10.1002/1878-0261.13453
By:
- Dufrusine, Beatrice;
- Capone, Emily;
- Ponziani, Sara;
- Lattanzio, Rossano;
- Lanuti, Paola;
- Giansanti, Francesco;
- De Laurenzi, Vincenzo;
- Iacobelli, Stefano;
- Ippoliti, Rodolfo;
- Mangiola, Annunziato;
- Trevisi, Gianluca;
- Sala, Gianluca
Publication type:
Article
Development of an anti‐BAG3 humanized antibody for treatment of pancreatic cancer.
Published in:
Molecular Oncology, 2019, v. 13, n. 6, p. 1388, doi. 10.1002/1878-0261.12492
By:
- Basile, Anna;
- De Marco, Margot;
- Festa, Michelina;
- Falco, Antonia;
- Iorio, Vittoria;
- Guerriero, Luana;
- Eletto, Daniela;
- Rea, Domenica;
- Arra, Claudio;
- Lamolinara, Alessia;
- Ballerini, Patrizia;
- Damiani, Verena;
- Rosati, Alessandra;
- Sala, Gianluca;
- Turco, Maria Caterina;
- Marzullo, Liberato;
- De Laurenzi, Vincenzo
Publication type:
Article
Accounting for the effect of forest and fragmentation in probabilistic rockfall hazard.
Published in:
Natural Hazards & Earth System Sciences, 2023, v. 23, n. 6, p. 2349, doi. 10.5194/nhess-23-2349-2023
By:
- Lanfranconi, Camilla;
- Frattini, Paolo;
- Sala, Gianluca;
- Dattola, Giuseppe;
- Bertolo, Davide;
- Sun, Juanjuan;
- Crosta, Giovanni Battista
Publication type:
Article
miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction.
Published in:
FASEB Journal, 2019, v. 33, n. 6, p. 6933, doi. 10.1096/fj.201802547R
By:
- Saul, Meike J.;
- Baumann, Isabell;
- Bruno, Annalisa;
- Emmerich, Anne C.;
- Wellstein, Julia;
- Ottinger, Sarah M.;
- Contursi, Annalisa;
- Dovizio, Melania;
- Donnini, Sandra;
- Tacconelli, Stefania;
- Raouf, Joan;
- Idborg, Helena;
- Stein, Stefan;
- Korotkova, Marina;
- Savai, Rajkumar;
- Terzuoli, Erika;
- Sala, Gianluca;
- Seeger, Werner;
- Jakobsson, Per-Johan;
- Patrignani, Paola
Publication type:
Article
BAG3 induces fibroblasts to release key cytokines involved in pancreatic cell migration.
Published in:
Journal of Cellular Biochemistry, 2022, v. 123, n. 1, p. 65, doi. 10.1002/jcb.30172
By:
- Dufrusine, Beatrice;
- Damiani, Verena;
- Capone, Emily;
- Pieragostino, Damiana;
- Dainese, Enrico;
- De Marco, Margot;
- Reppucci, Francesca;
- Turco, Maria C.;
- Rosati, Alessandra;
- Marzullo, Liberato;
- Sala, Gianluca;
- Sallese, Michele;
- De Laurenzi, Vincenzo
Publication type:
Article
Cover Image, Volume 123, Number 1, January 2022.
Published in:
Journal of Cellular Biochemistry, 2022, v. 123, n. 1, p. i, doi. 10.1002/jcb.30223
By:
- Dufrusine, Beatrice;
- Damiani, Verena;
- Capone, Emily;
- Pieragostino, Damiana;
- Dainese, Enrico;
- De Marco, Margot;
- Reppucci, Francesca;
- Turco, Maria C.;
- Rosati, Alessandra;
- Marzullo, Liberato;
- Sala, Gianluca;
- Sallese, Michele;
- De Laurenzi, Vincenzo
Publication type:
Article
Role of galectin 3 binding protein in cancer progression: a potential novel therapeutic target.
Published in:
2021
By:
- Capone, Emily;
- Iacobelli, Stefano;
- Sala, Gianluca
Publication type:
journal article
PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes.
Published in:
2019
By:
- Lattanzio, Rossano;
- Iezzi, Manuela;
- Sala, Gianluca;
- Tinari, Nicola;
- Falasca, Marco;
- Alberti, Saverio;
- Buglioni, Simonetta;
- Mottolese, Marcella;
- Perracchio, Letizia;
- Natali, Pier Giorgio;
- Piantelli, Mauro
Publication type:
journal article
LGALS3BP is a potential target of antibody‐drug conjugates in oral squamous cell carcinoma.
Published in:
Oral Diseases, 2024, v. 30, n. 4, p. 2039, doi. 10.1111/odi.14719
By:
- Cela, Ilaria;
- Caponio, Vito Carlo Alberto;
- Capone, Emily;
- Pinti, Morena;
- Mascitti, Marco;
- Togni, Lucrezia;
- Lo Muzio, Lorenzo;
- Rubini, Corrado;
- De Laurenzi, Vincenzo;
- Lattanzio, Rossano;
- Perrotti, Vittoria;
- Sala, Gianluca
Publication type:
Article
Breast cancer in the era of integrating "Omics" approaches.
Published in:
Oncogenesis, 2022, v. 11, n. 1, p. 1, doi. 10.1038/s41389-022-00393-8
By:
- Rossi, Claudia;
- Cicalini, Ilaria;
- Cufaro, Maria Concetta;
- Consalvo, Ada;
- Upadhyaya, Prabin;
- Sala, Gianluca;
- Antonucci, Ivana;
- Del Boccio, Piero;
- Stuppia, Liborio;
- De Laurenzi, Vincenzo
Publication type:
Article
USP19 modulates cancer cell migration and invasion and acts as a novel prognostic marker in patients with early breast cancer.
Published in:
Oncogenesis, 2021, v. 10, n. 3, p. 1, doi. 10.1038/s41389-021-00318-x
By:
- Rossi, Fabiana Alejandra;
- Enriqué Steinberg, Juliana Haydeé;
- Calvo Roitberg, Ezequiel Hernán;
- Joshi, Molishree Umesh;
- Pandey, Ahwan;
- Abba, Martin Carlos;
- Dufrusine, Beatrice;
- Buglioni, Simonetta;
- De Laurenzi, Vincenzo;
- Sala, Gianluca;
- Lattanzio, Rossano;
- Espinosa, Joaquín Maximiliano;
- Rossi, Mario
Publication type:
Article
Repurposing a psychoactive drug for children with cancer: p27Kip1-dependent inhibition of metastatic neuroblastomas by Prozac.
Published in:
Oncogenesis, 2020, v. 9, n. 1, p. 1, doi. 10.1038/s41389-019-0186-3
By:
- Bibbo', Sandra;
- Lamolinara, Alessia;
- Capone, Emily;
- Purgato, Stefania;
- Tsakaneli, Alexia;
- Panella, Valeria;
- Sallese, Michele;
- Rossi, Cosmo;
- Ciufici, Paolo;
- Nieddu, Valentina;
- De Laurenzi, Vincenzo;
- Iezzi, Manuela;
- Perini, Giovanni;
- Sala, Gianluca;
- Sala, Arturo
Publication type:
Article
EV20-sss-vc/MMAF, an HER-3 targeting antibody-drug conjugate displays antitumor activity in liver cancer.
Published in:
Oncology Reports, 2021, v. 45, n. 2, p. 776
By:
- D'Agostino, Daniela;
- Gentile, Roberta;
- Ponziani, Sara;
- Di Vittorio, Giulia;
- Dituri, Francesco;
- Giannelli, Gianluigi;
- Rossi, Cosmo;
- Marzullo, Liberato;
- Giansanti, Francesco;
- De Laurenzi, Vincenzo;
- Iacobelli, Stefano;
- Ippoliti, Rodolfo;
- Capone, Emily;
- Sala, Gianluca
Publication type:
Article

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