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Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37349-4
By:
- Sadegh, Sepideh;
- Skelton, James;
- Anastasi, Elisa;
- Maier, Andreas;
- Adamowicz, Klaudia;
- Möller, Anna;
- Kriege, Nils M.;
- Kronberg, Jaanika;
- Haller, Toomas;
- Kacprowski, Tim;
- Wipat, Anil;
- Baumbach, Jan;
- Blumenthal, David B.
Publication type:
Article
Network medicine for disease module identification and drug repurposing with the NeDRex platform.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27138-2
By:
- Sadegh, Sepideh;
- Skelton, James;
- Anastasi, Elisa;
- Bernett, Judith;
- Blumenthal, David B.;
- Galindez, Gihanna;
- Salgado-Albarrán, Marisol;
- Lazareva, Olga;
- Flanagan, Keith;
- Cockell, Simon;
- Nogales, Cristian;
- Casas, Ana I.;
- Schmidt, Harald H. H. W.;
- Baumbach, Jan;
- Wipat, Anil;
- Kacprowski, Tim
Publication type:
Article
Robust disease module mining via enumeration of diverse prize-collecting Steiner trees.
Published in:
Bioinformatics, 2022, v. 38, n. 6, p. 1600, doi. 10.1093/bioinformatics/btab876
By:
- Bernett, Judith;
- Krupke, Dominik;
- Sadegh, Sepideh;
- Baumbach, Jan;
- Fekete, Sándor P;
- Kacprowski, Tim;
- List, Markus;
- Blumenthal, David B
Publication type:
Article
NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.
Published in:
PLoS Biology, 2020, v. 18, n. 11, p. 1, doi. 10.1371/journal.pbio.3000885
By:
- Elbatreek, Mahmoud H.;
- Sadegh, Sepideh;
- Anastasi, Elisa;
- Guney, Emre;
- Nogales, Cristian;
- Kacprowski, Tim;
- Hassan, Ahmed A.;
- Teubner, Andreas;
- Huang, Po-Hsun;
- Hsu, Chien-Yi;
- Schiffers, Paul M. H.;
- Janssen, Ger M.;
- Kleikers, Pamela W. M.;
- Wipat, Anil;
- Baumbach, Jan;
- De Mey, Jo G. R.;
- Schmidt, Harald H. H. W.
Publication type:
Article
Individuating Possibly Repurposable Drugs and Drug Targets for COVID-19 Treatment Through Hypothesis-Driven Systems Medicine Using CoVex.
Published in:
Assay & Drug Development Technologies, 2020, v. 18, n. 8, p. 348, doi. 10.1089/adt.2020.1010
By:
- Matschinske, Julian;
- Salgado-Albarrán, Marisol;
- Sadegh, Sepideh;
- Bongiovanni, Dario;
- Baumbach, Jan;
- Blumenthal, David B.
Publication type:
Article
Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17189-2
By:
- Sadegh, Sepideh;
- Matschinske, Julian;
- Blumenthal, David B.;
- Galindez, Gihanna;
- Kacprowski, Tim;
- List, Markus;
- Nasirigerdeh, Reza;
- Oubounyt, Mhaned;
- Pichlmair, Andreas;
- Rose, Tim Daniel;
- Salgado-Albarrán, Marisol;
- Späth, Julian;
- Stukalov, Alexey;
- Wenke, Nina K.;
- Yuan, Kevin;
- Pauling, Josch K.;
- Baumbach, Jan
Publication type:
Article

Found: 6

Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond.

Network medicine for disease module identification and drug repurposing with the NeDRex platform.

Robust disease module mining via enumeration of diverse prize-collecting Steiner trees.

NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype.

Individuating Possibly Repurposable Drugs and Drug Targets for COVID-19 Treatment Through Hypothesis-Driven Systems Medicine Using CoVex.

Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing.