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Immune enhancement of nitroreductase-induced cytotoxicity: Studies using a bicistronic adenovirus vector.
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- International Journal of Cancer, 2003, v. 104, n. 1, p. 104, doi. 10.1002/ijc.10916
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Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase.
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- International Journal of Cancer, 2000, v. 86, n. 6, p. 848, doi. 10.1002/(SICI)1097-0215(20000615)86:6<848::AID-IJC14>3.0.CO;2-B
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- Article
The 3D‐structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP<sup>+</sup> provide glimpses of its catalytic mechanism.
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- FEBS Letters, 2022, v. 596, n. 18, p. 2425, doi. 10.1002/1873-3468.14413
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- Article
Synergistic anti-tumor effects of nitroreductase mutants and p53.
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- Journal of Cancer Research & Therapeutics, 2014, v. 10, n. 3, p. 665, doi. 10.4103/0973-1482.139155
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- Article
Structure and Dynamics of Three Escherichia coli NfsB Nitro-Reductase Mutants Selected for Enhanced Activity with the Cancer Prodrug CB1954.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5987, doi. 10.3390/ijms24065987
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- Article
Production of Retroviral Vectors for Gene Therapy with the Human Packaging Cell Line FLYRD18.
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- Biotechnology Progress, 1999, v. 15, n. 5, p. 941, doi. 10.1021/bp990085b
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- Article
NITROREDUCTASE: A PRODRUG-ACTIVATING ENZYME FOR CANCER GENE THERAPY.
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- Clinical & Experimental Pharmacology & Physiology, 2004, v. 31, n. 11, p. 811, doi. 10.1111/j.1440-1681.2004.04085.x
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- Article
The structures of E. coli NfsA bound to the antibiotic nitrofurantoin; to 1,4-benzoquinone and to FMN.
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- Biochemical Journal, 2021, v. 478, n. 13, p. 2601, doi. 10.1042/BCJ20210160
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- Article
Minimal RB-responsive E1A Promoter Modification to Attain Potency, Selectivity, and Transgene-arming Capacity in Oncolytic Adenoviruses.
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- Molecular Therapy, 2010, v. 18, n. 11, p. 1960, doi. 10.1038/mt.2010.173
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- Article
A Phase I/II Clinical Trial in Localized Prostate Cancer of an Adenovirus Expressing Nitroreductase with CB1984.
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- Molecular Therapy, 2009, v. 17, n. 7, p. 1292, doi. 10.1038/mt.2009.80
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- Article
Expression of Escherichia coli B nitroreductase in established human tumor xenografts in mice results in potent antitumoral and bystander effects upon systemic administration of the prodrug CB1954.
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- Cancer Gene Therapy, 2000, v. 7, n. 5, p. 721, doi. 10.1038/sj.cgt.7700171
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- Article
Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences.
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- Nature, 1985, v. 317, n. 6040, p. 828, doi. 10.1038/317828a0
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- Article
Adenovirus-Mediated Expression of Dominant Negative Fibroblast Growth Factor (FGF) Receptor 1 in Thyroid Cells Blocks FGF Effects and Reduces Goitrogenesis in Mice.
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- Journal of Clinical Endocrinology & Metabolism, 2003, v. 88, n. 9, p. 4472, doi. 10.1210/jc.2003-030333
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- Article
Co-stimulation with 4-1BB ligand allows extended T-cell proliferation, synergizes with CD80/CD86 and can reactivate anergic T cells.
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- International Immunology, 2007, v. 19, n. 12, p. 1383, doi. 10.1093/intimm/dxm106
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- Article
Oxygen‐insensitive nitroreductase E. coliNfsA, but not NfsB, is inhibited by fumarate.
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- Proteins, 2023, v. 91, n. 5, p. 585, doi. 10.1002/prot.26451
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- Article
Vectors based on reducible polycations facilitate intracellular release of nucleic acids.
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- Journal of Gene Medicine, 2003, v. 5, n. 3, p. 232, doi. 10.1002/jgm.331
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- Article
CD40 ligand induced cytotoxicity in carcinomacells is enhanced by inhibition ofmetalloproteinase cleavage and delivery via aconditionally-replicating adenovirus.
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- Molecular Cancer, 2010, v. 9, p. 52, doi. 10.1186/1476-4598-9-52
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