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Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in mice.
Published in:
2011
By:
- Lerner, Immanuel;
- Hermano, Esther;
- Zcharia, Eyal;
- Rodkin, Dina;
- Bulvik, Raanan;
- Doviner, Victoria;
- Rubinstein, Ariel M.;
- Ishai-Michaeli, Rivka;
- Atzmon, Ruth;
- Sherman, Yoav;
- Meirovitz, Amichay;
- Peretz, Tamar;
- Vlodavsky, Israel;
- Elkin, Michael
Publication type:
journal article
Computational quantification and characterization of independently evolving cellular subpopulations within tumors is critical to inhibit anti-cancer therapy resistance.
Published in:
Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01121-y
By:
- Alkhatib, Heba;
- Rubinstein, Ariel M.;
- Vasudevan, Swetha;
- Flashner-Abramson, Efrat;
- Stefansky, Shira;
- Chowdhury, Sangita Roy;
- Oguche, Solomon;
- Peretz-Yablonsky, Tamar;
- Granit, Avital;
- Granot, Zvi;
- Ben-Porath, Ittai;
- Sheva, Kim;
- Feldman, Jon;
- Cohen, Noa E.;
- Meirovitz, Amichay;
- Kravchenko-Balasha, Nataly
Publication type:
Article
Six3 regulates optic nerve development via multiple mechanisms.
Published in:
Scientific Reports, 2016, p. 20267, doi. 10.1038/srep20267
By:
- Samuel, Anat;
- Rubinstein, Ariel M.;
- Azar, Tehila T.;
- Ben-Moshe Livne, Zohar;
- Kim, Seok-Hyung;
- Inbal, Adi
Publication type:
Article
Heparanase: a potential marker of worse prognosis in estrogen receptor-positive breast cancer.
Published in:
NPJ Breast Cancer, 2021, v. 7, n. 1, p. 1, doi. 10.1038/s41523-021-00277-x
By:
- Zahavi, Tamar;
- Salmon-Divon, Mali;
- Salgado, Roberto;
- Elkin, Michael;
- Hermano, Esther;
- Rubinstein, Ariel M.;
- Francis, Prudence A.;
- Di Leo, Angelo;
- Viale, Giuseppe;
- de Azambuja, Evandro;
- Ameye, Lieveke;
- Sotiriou, Christos;
- Salmon, Asher;
- Kravchenko-Balasha, Nataly;
- Sonnenblick, Amir
Publication type:
Article
Drug-Induced Resistance and Phenotypic Switch in Triple-Negative Breast Cancer Can Be Controlled via Resolution and Targeting of Individualized Signaling Signatures.
Published in:
Cancers, 2021, v. 13, n. 19, p. 5009, doi. 10.3390/cancers13195009
By:
- Vasudevan, Swetha;
- Adejumobi, Ibukun A.;
- Alkhatib, Heba;
- Roy Chowdhury, Sangita;
- Stefansky, Shira;
- Rubinstein, Ariel M.;
- Kravchenko-Balasha, Nataly
Publication type:
Article
Induction of heparanase by HPV E6 oncogene in head and neck squamous cell carcinoma.
Published in:
Journal of Cellular & Molecular Medicine, 2014, v. 18, n. 1, p. 181, doi. 10.1111/jcmm.12179
By:
- Hirshoren, Nir;
- Bulvik, Raanan;
- Neuman, Tzahi;
- Rubinstein, Ariel M.;
- Meirovitz, Amichay;
- Elkin, Michael
Publication type:
Article
Dichotomic role of heparanase in a murine model of metabolic syndrome.
Published in:
Cellular & Molecular Life Sciences, 2021, v. 78, n. 6, p. 2771, doi. 10.1007/s00018-020-03660-2
By:
- Hermano, Esther;
- Carlotti, Françoise;
- Abecassis, Alexia;
- Meirovitz, Amichay;
- Rubinstein, Ariel M.;
- Li, Jin-Ping;
- Vlodavsky, Israel;
- Rabelink, Ton J.;
- Elkin, Michael
Publication type:
Article
Heparanase in inflammation and inflammation-associated cancer.
Published in:
FEBS Journal, 2013, v. 280, n. 10, p. 2307, doi. 10.1111/febs.12184
By:
- Meirovitz, Amichay;
- Goldberg, Rachel;
- Binder, Adi;
- Rubinstein, Ariel M.;
- Hermano, Esther;
- Elkin, Michael
Publication type:
Article
Patient-specific signaling signatures predict optimal therapeutic combinations for triple negative breast cancer.
Published in:
Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-023-01921-9
By:
- Alkhatib, Heba;
- Conage-Pough, Jason;
- Roy Chowdhury, Sangita;
- Shian, Denen;
- Zaid, Deema;
- Rubinstein, Ariel M.;
- Sonnenblick, Amir;
- Peretz-Yablonsky, Tamar;
- Granit, Avital;
- Carmon, Einat;
- Kohale, Ishwar N.;
- Boughey, Judy C.;
- Goetz, Matthew P.;
- Wang, Liewei;
- White, Forest M.;
- Kravchenko-Balasha, Nataly
Publication type:
Article
Radiation-Induced Nephropathy in the Murine Model Is Ameliorated by Targeting Heparanase.
Published in:
Biomedicines, 2023, v. 11, n. 3, p. 710, doi. 10.3390/biomedicines11030710
By:
- Abecassis, Alexia;
- Hermano, Esther;
- Sheva, Kim;
- Rubinstein, Ariel M.;
- Elkin, Michael;
- Meirovitz, Amichay
Publication type:
Article
Macrophages Upregulate Estrogen Receptor Expression in the Model of Obesity-Associated Breast Carcinoma.
Published in:
Cells (2073-4409), 2022, v. 11, n. 18, p. N.PAG, doi. 10.3390/cells11182844
By:
- Nahmias Blank, Daniela;
- Hermano, Esther;
- Sonnenblick, Amir;
- Maimon, Ofra;
- Rubinstein, Ariel M.;
- Drai, Emmy;
- Maly, Bella;
- Vlodavsky, Israel;
- Popovtzer, Aron;
- Peretz, Tamar;
- Meirovitz, Amichay;
- Elkin, Michael
Publication type:
Article
Overcoming resistance to EGFR monotherapy in HNSCC by identification and inhibition of individualized cancer processes.
Published in:
Theranostics, 2022, v. 12, n. 3, p. 1204, doi. 10.7150/thno.64347
By:
- Jubran, Maria R.;
- Vilenski, Daniela;
- Flashner-Abramson, Efrat;
- Shnaider, Efraim;
- Vasudevan, Swetha;
- Rubinstein, Ariel M.;
- Meirovitz, Amichay;
- Sharon, Shay;
- Polak, David;
- Kravchenko-Balasha, Nataly
Publication type:
Article
NEROFE - A novel human hormone-peptide with anti-cancer activity.
Published in:
Journal of Experimental Therapeutics & Oncology, 2010, v. 8, n. 4, p. 327
By:
- Sandler, Uziel;
- Devary, Orly;
- Braitbard, Ori;
- Ohana, Joel;
- Kass, Gideon;
- Rubinstein, Ariel M.;
- Friedman, Zeev Y.;
- Devary, Yoram
Publication type:
Article
Dissecting the role of crosstalk between glioblastoma subpopulations in tumor cell spreading.
Published in:
Oncogenesis, 2020, v. 9, n. 2, p. 1, doi. 10.1038/s41389-020-0199-y
By:
- Jubran, Maria R.;
- Rubinstein, Ariel M.;
- Cojocari, Irina;
- Adejumobi, Ibukun Adesoji;
- Mogilevsky, Maxim;
- Tibi, Sama;
- Sionov, Ronit V.;
- Verreault, Maïté;
- Idbaih, Ahmed;
- Karni, Rotem;
- Kravchenko-Balasha, Nataly
Publication type:
Article
Regulation of Heparanase in Diabetes-Associated Pancreatic Carcinoma.
Published in:
Frontiers in Oncology, 2019, v. 9, p. 1, doi. 10.3389/fonc.2019.01405
By:
- Goldberg, Rachel;
- Meirovitz, Amichay;
- Abecassis, Alexia;
- Hermano, Esther;
- Rubinstein, Ariel M.;
- Nahmias, Daniela;
- Grinshpun, Albert;
- Peretz, Tamar;
- Elkin, Michael
Publication type:
Article
Role of Heparanase-Driven Inflammatory Cascade in Pathogenesis of Diabetic Nephropathy.
Published in:
Diabetes, 2014, v. 63, n. 12, p. 4302, doi. 10.2337/db14-0001
By:
- Goldberg, Rachel;
- Rubinstein, Ariel M.;
- Gil, Natali;
- Hermano, Esther;
- Jin-Ping Li;
- van der Vlag, Johan;
- Atzmon, Ruth;
- Meirovitz, Amichay;
- Elkin, Michael
Publication type:
Article
Heparanase is essential for the development of diabetic nephropathy in mice.
Published in:
2012
By:
- Gil N;
- Goldberg R;
- Neuman T;
- Garsen M;
- Zcharia E;
- Rubinstein AM;
- van Kuppevelt T;
- Meirovitz A;
- Pisano C;
- Li JP;
- van der Vlag J;
- Vlodavsky I;
- Elkin M;
- Gil, Natali;
- Goldberg, Rachel;
- Neuman, Tzahi;
- Garsen, Marjolein;
- Zcharia, Eyal;
- Rubinstein, Ariel M;
- van Kuppevelt, Toin
Publication type:
journal article
Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice.
Published in:
Diabetes, 2012, v. 61, n. 1, p. 208, doi. 10.2337/db11-1024
By:
- Gil, Natali;
- Goldberg, Rachel;
- Neuman, Tzahi;
- Garsen, Marjolein;
- Zcharia, Eyal;
- Rubinstein, Ariel M.;
- Van Kuppevelt, Toin;
- Meirovitz, Amichay;
- Pisano, Claudio;
- Jin-Ping Li;
- Van der Vlag, Johan;
- Vlodavsky, Israel;
- Elkin, Michael
Publication type:
Article

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