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Molecular cloning of foot and mouth disease virus genome and nucleotide sequences in the structural protein genes.
Published in:
Nature, 1981, v. 290, n. 5809, p. 800, doi. 10.1038/290800a0
By:
- Boothroyd, John C.;
- Highfield, Peter E.;
- Cross, George A. M.;
- Rowlands, David J.;
- Lowe, Peter A.;
- Brown, Fred;
- Harris, Timothy J. R.
Publication type:
Article
Continuous, Automated Breathing Rate and Body Motion Monitoring of Rats With Paraquat-Induced Progressive Lung Injury.
Published in:
Frontiers in Physiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphys.2020.569001
By:
- Baran, Szczepan W.;
- Gupta, Ayan Das;
- Lim, Maria A.;
- Mathur, Ashwini;
- Rowlands, David J.;
- Schaevitz, Laura R.;
- Shanmukhappa, Shiva K.;
- Walker, Dana B.
Publication type:
Article
Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate.
Published in:
PLoS Pathogens, 2024, v. 20, n. 9, p. 1, doi. 10.1371/journal.ppat.1012511
By:
- Kingston, Natalie J.;
- Snowden, Joseph S.;
- Grehan, Keith;
- Hall, Philippa K.;
- Hietanen, Eero V.;
- Passchier, Tim C.;
- Polyak, Stephen J.;
- Filman, David J.;
- Hogle, James M.;
- Rowlands, David J.;
- Stonehouse, Nicola J.
Publication type:
Article
Activation of TNFR1 ectodomain shedding by mitochondrial Ca2+ determines the severity of inflammation in mouse lung microvessels.
Published in:
2011
By:
- Rowlands, David J.;
- Islam, Mohammad Naimul;
- Das, Shonit R.;
- Huertas, Alice;
- Quadri, Sadiqa K.;
- Horiuchi, Keisuke;
- Inamdar, Nilufar;
- Emin, Memet T.;
- Lindert, Jens;
- Ten, Vadim S.;
- Bhattacharya, Sunita;
- Bhattacharya, Jahar
Publication type:
journal article
Mechanisms underlying β2-adrenoceptor-mediated nitric oxide generation by human umbilical vein endothelial cells.
Published in:
Journal of Physiology, 2006, v. 576, n. 2, p. 585, doi. 10.1113/jphysiol.2006.115998
By:
- Queen, Lindsay R.;
- Ji, Yong;
- Xu, Biao;
- Young, Lora;
- Yao, Kang;
- Wyatt, Amanda W.;
- Rowlands, David J.;
- Siow, Richard C. M.;
- Mann, Giovanni E.;
- Ferro, Albert
Publication type:
Article
Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.52555
By:
- Shaw, Joseph;
- Gosain, Rajendra;
- Kalita, Monoj Mon;
- Foster, Toshana L.;
- Kankanala, Jayakanth;
- Mahato, D. Ram;
- Abas, Sonia;
- King, Barnabas J.;
- Scott, Claire;
- Brown, Emma;
- Bentham, Matthew J.;
- Wetherill, Laura;
- Bloy, Abigail;
- Samson, Adel;
- Harris, Mark;
- Mankouri, Jamel;
- Rowlands, David J.;
- Macdonald, Andrew;
- Tarr, Alexander W.;
- Fischer, Wolfgang B.
Publication type:
Article
An Engineered Maturation Cleavage Provides a Recombinant Mimic of Foot-and-Mouth Disease Virus Capsid Assembly-Disassembly.
Published in:
Life (2075-1729), 2021, v. 11, n. 6, p. 500, doi. 10.3390/life11060500
By:
- Newman, Joseph;
- Rowlands, David J.;
- Tuthill, Tobias J.
Publication type:
Article
Efficacy and Safety of the CFTR Potentiator Icenticaftor (QBW251) in COPD: Results from a Phase 2 Randomized Trial.
Published in:
International Journal of COPD, 2020, v. 15, p. 2399, doi. 10.2147/COPD.S257474
By:
- Rowe, Steven M;
- Jones, Ieuan;
- Dransfield, Mark T;
- Haque, Nazmul;
- Gleason, Stephen;
- Hayes, Katy A;
- Kulmatycki, Kenneth;
- Yates, Denise P;
- Danahay, Henry;
- Gosling, Martin;
- Rowlands, David J;
- Grant, Sarah S
Publication type:
Article
Front Cover: Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein (ChemMedChem 10/2023).
Published in:
ChemMedChem, 2023, v. 18, n. 10, p. 1, doi. 10.1002/cmdc.202300251
By:
- Kejriwal, Rishabh;
- Evans, Tristan;
- Calabrese, Joshua;
- Swistak, Lea;
- Alexandrescu, Lauren;
- Cohen, Michelle;
- Rahman, Nahian;
- Henriksen, Niel;
- Charan Dash, Radha;
- Hadden, M. Kyle;
- Stonehouse, Nicola J.;
- Rowlands, David J.;
- Kingston, Natalie J.;
- Hartnoll, Madeline;
- Dobson, Samuel J.;
- White, Simon J.
Publication type:
Article
Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein.
Published in:
ChemMedChem, 2023, v. 18, n. 10, p. 1, doi. 10.1002/cmdc.202200541
By:
- Kejriwal, Rishabh;
- Evans, Tristan;
- Calabrese, Joshua;
- Swistak, Lea;
- Alexandrescu, Lauren;
- Cohen, Michelle;
- Rahman, Nahian;
- Henriksen, Niel;
- Charan Dash, Radha;
- Hadden, M. Kyle;
- Stonehouse, Nicola J.;
- Rowlands, David J.;
- Kingston, Natalie J.;
- Hartnoll, Madeline;
- Dobson, Samuel J.;
- White, Simon J.
Publication type:
Article
Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury.
Published in:
Nature Medicine, 2012, v. 18, n. 5, p. 759, doi. 10.1038/nm.2736
By:
- Islam, Mohammad Naimul;
- Das, Shonit R;
- Emin, Memet T;
- Wei, Michelle;
- Sun, Li;
- Westphalen, Kristin;
- Rowlands, David J;
- Quadri, Sadiqa K;
- Bhattacharya, Sunita;
- Bhattacharya, Jahar
Publication type:
Article
More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules.
Published in:
Nature Structural & Molecular Biology, 2014, v. 21, n. 3, p. 282, doi. 10.1038/nsmb.2769
By:
- De Colibus, Luigi;
- Wang, Xiangxi;
- Spyrou, John A B;
- Kelly, James;
- Ren, Jingshan;
- Grimes, Jonathan;
- Puerstinger, Gerhard;
- Stonehouse, Nicola;
- Walter, Thomas S;
- Hu, Zhongyu;
- Wang, Junzhi;
- Li, Xuemei;
- Peng, Wei;
- Rowlands, David J;
- Fry, Elizabeth E;
- Rao, Zihe;
- Stuart, David I
Publication type:
Article
A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.
Published in:
Nature Structural & Molecular Biology, 2012, v. 19, n. 4, p. 424, doi. 10.1038/nsmb.2255
By:
- Wang, Xiangxi;
- Peng, Wei;
- Ren, Jingshan;
- Hu, Zhongyu;
- Xu, Jiwei;
- Lou, Zhiyong;
- Li, Xumei;
- Yin, Weidong;
- Shen, Xinliang;
- Porta, Claudine;
- Walter, Thomas S;
- Evans, Gwyndaf;
- Axford, Danny;
- Owen, Robin;
- Rowlands, David J;
- Wang, Junzhi;
- Stuart, David I;
- Fry, Elizabeth E;
- Rao, Zihe
Publication type:
Article
A uthors' R eply.
Published in:
BJOG: An International Journal of Obstetrics & Gynaecology, 1996, v. 103, n. 8, p. 852, doi. 10.1111/j.1471-0528.1996.tb09894.x
By:
- Rowlands, David J;
- Vyas, Sanjay
Publication type:
Article
Longitudinal study of fetal middle cerebral artery flow velocity waveforms preceding fetal death.
Published in:
BJOG: An International Journal of Obstetrics & Gynaecology, 1995, v. 102, n. 11, p. 888, doi. 10.1111/j.1471-0528.1995.tb10876.x
By:
- Rowlands, David J.;
- Vyas, Sanjay K.
Publication type:
Article
Tandem Fusion of Hepatitis B Core Antigen Allows Assembly of Virus-Like Particles in Bacteria and Plants with Enhanced Capacity to Accommodate Foreign Proteins.
Published in:
PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0120751
By:
- Peyret, Hadrien;
- Gehin, Annick;
- Thuenemann, Eva C.;
- Blond, Donatienne;
- El Turabi, Aadil;
- Beales, Lucy;
- Clarke, Dean;
- Gilbert, Robert J. C.;
- Fry, Elizabeth E.;
- Stuart, David I.;
- Holmes, Kris;
- Stonehouse, Nicola J.;
- Whelan, Mike;
- Rosenberg, William;
- Lomonossoff, George P.;
- Rowlands, David J.
Publication type:
Article
Non-responsiveness to a foot-and-mouth disease virus peptide overcome by addition of foreign helper T-cell determinants.
Published in:
Nature, 1987, v. 330, n. 6144, p. 168, doi. 10.1038/330168a0
By:
- Francis, Michael J.;
- Hastings, Gillian Z.;
- Syred, Andrew D.;
- McGinn, Brian;
- Brown, Fred;
- Rowlands, David J.
Publication type:
Article
Activation of endothelial nitric oxide synthase by dietary isoflavones: Role of NO in Nrf2-mediated antioxidant gene expression
Published in:
Cardiovascular Research, 2007, v. 75, n. 2, p. 261, doi. 10.1016/j.cardiores.2007.04.004
By:
- Mann, Giovanni E.;
- Rowlands, David J.;
- Li, Francois Y.L.;
- de Winter, Patricia;
- Siow, Richard C.M.
Publication type:
Article
The dual role of a highly structured RNA (the S fragment) in the replication of foot‐and‐mouth disease virus.
Published in:
FASEB Journal, 2024, v. 38, n. 14, p. 1, doi. 10.1096/fj.202400500R
By:
- Ward, Joseph C.;
- Lasecka‐Dykes, Lidia;
- Dobson, Samuel J.;
- Gold, Sarah;
- Kingston, Natalie J.;
- Herod, Morgan R.;
- King, Donald P.;
- Tuthill, Tobias J.;
- Rowlands, David J.;
- Stonehouse, Nicola J.
Publication type:
Article
Functional advantages of triplication of the 3B coding region of the FMDV genome.
Published in:
FASEB Journal, 2021, v. 35, n. 2, p. 1, doi. 10.1096/fj.202001473RR
By:
- Adeyemi, Oluwapelumi O.;
- Ward, Joseph C.;
- Snowden, Joseph S.;
- Herod, Morgan R.;
- Rowlands, David J.;
- Stonehouse, Nicola J.
Publication type:
Article
Production and purification of chimeric HBc virus-like particles carrying influenza virus LAH domain as vaccine candidates.
Published in:
BMC Biotechnology, 2017, v. 17, p. 1, doi. 10.1186/s12896-017-0396-8
By:
- Kazaks, Andris;
- I-Na Lu;
- Farinelle, Sophie;
- Ramirez, Alex;
- Crescente3, Vincenzo;
- Blaha, Benjamin;
- Ogonah, Olotu;
- Mukhopadhyay, Tarit;
- de Obanos, Mapi Perez;
- Krimer, Alejandro;
- Akopjana, Inara;
- Bogans, Janis;
- Ose, Velta;
- Kirsteina, Anna;
- Kazaka, Tatjana;
- Stonehouse, Nicola J.;
- Rowlands, David J.;
- Muller, Claude P.;
- Tars, Kaspars;
- Rosenberg, William M.
Publication type:
Article
MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension.
Published in:
2016
By:
- Rothman, Alexander M. K.;
- Arnold, Nadine D.;
- Pickworth, Josephine A.;
- Iremonger, James;
- Ciuclan, Loredana;
- Allen, Robert M. H.;
- Guth-Gundel, Sabine;
- Southwood, Mark;
- Morrell, Nicholas W.;
- Thomas, Matthew;
- Francis, Sheila E.;
- Rowlands, David J.;
- Lawrie, Allan
Publication type:
journal article
Picornavirus uncoating intermediate captured in atomic detail.
Published in:
Nature Communications, 2013, v. 4, n. 6, p. 1929, doi. 10.1038/ncomms2889
By:
- Ren, Jingshan;
- Wang, Xiangxi;
- Hu, Zhongyu;
- Gao, Qiang;
- Sun, Yao;
- Li, Xuemei;
- Porta, Claudine;
- Walter, Thomas S.;
- Gilbert, Robert J.;
- Zhao, Yuguang;
- Axford, Danny;
- Williams, Mark;
- McAuley, Katherine;
- Rowlands, David J.;
- Yin, Weidong;
- Wang, Junzhi;
- Stuart, David I.;
- Rao, Zihe;
- Fry, Elizabeth E.
Publication type:
Article
Production and Characterisation of Stabilised PV-3 Virus-like Particles Using Pichia pastoris.
Published in:
Viruses (1999-4915), 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/v14102159
By:
- Sherry, Lee;
- Grehan, Keith;
- Swanson, Jessica J.;
- Bahar, Mohammad W.;
- Porta, Claudine;
- Fry, Elizabeth E.;
- Stuart, David I.;
- Rowlands, David J.;
- Stonehouse, Nicola J.
Publication type:
Article
Sex-Dependent Influence of Endogenous Estrogen in Pulmonary Hypertension.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2014, v. 190, n. 4, p. 456, doi. 10.1164/rccm.201403-0483OC
By:
- Mair, Kirsty M.;
- Wright, Audrey F.;
- Duggan, Nicholas;
- Rowlands, David J.;
- Hussey, Martin J.;
- Roberts, Sonia;
- Fullerton, Josephine;
- Nilsen, Margaret;
- Loughlin, Lynn;
- Thomas, Matthew;
- MacLean, Margaret R.
Publication type:
Article
Imatinib Attenuates Hypoxia-induced Pulmonary Arterial Hypertension Pathology via Reduction in 5-Hydroxytryptamine through Inhibition of Tryptophan Hydroxylase 1 Expression.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2013, v. 187, n. 1, p. 78, doi. 10.1164/rccm.201206-1028OC
By:
- Ciuclan, Loredana;
- Hussey, Martin J.;
- Burton, Victoria;
- Good, Robert;
- Duggan, Nicholas;
- Beach, Sarah;
- Jones, Peter;
- Fox, Roy;
- Clay, leuan;
- Bonneau, Olivier;
- Konstantinova, Irena;
- Pearce, Andrew;
- Rowlands, David J.;
- Jarai, Gabor;
- Westwick, John;
- MacLean, Margaret R.;
- Thomas, Matthew
Publication type:
Article
Capsid Protein VP4 of Human Rhinovirus Induces Membrane Permeability by the Formation of a Size-Selective Multimeric Pore.
Published in:
PLoS Pathogens, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.ppat.1004294
By:
- Panjwani, Anusha;
- Strauss, Mike;
- Gold, Sarah;
- Wenham, Hannah;
- Jackson, Terry;
- Chou, James J.;
- Rowlands, David J.;
- Stonehouse, Nicola J.;
- Hogle, James M.;
- Tuthill, Tobias J.
Publication type:
Article
Equine Rhinitis A Virus and Its Low pH Empty Particle: Clues Towards an Aphthovirus Entry Mechanism?
Published in:
PLoS Pathogens, 2009, v. 5, n. 10, p. 1, doi. 10.1371/journal.ppat.1000620
By:
- Tuthill, Tobias J.;
- Harlos, Karl;
- Walter, Thomas S.;
- Knowles, Nick J.;
- Groppelli, Elisabetta;
- Rowlands, David J.;
- Stuart, David I.;
- Fry, Elizabeth E.
Publication type:
Article
Infertility: The prognosis for assisted conception treatment after unexpected failure of fertilization in vitro: a comparative study.
Published in:
Human Reproduction, 1994, v. 9, n. 12, p. 2287
By:
- Rowlands, David J.;
- McDermott, Alan;
- Hull, Michael G.R.
Publication type:
Article
Structural insight into Pichia pastoris fatty acid synthase.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89196-2
By:
- Snowden, Joseph S.;
- Alzahrani, Jehad;
- Sherry, Lee;
- Stacey, Martin;
- Rowlands, David J.;
- Ranson, Neil A.;
- Stonehouse, Nicola J.
Publication type:
Article
Genetic economy in picornaviruses: Foot-and-mouth disease virus replication exploits alternative precursor cleavage pathways.
Published in:
PLoS Pathogens, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.ppat.1006666
By:
- Herod, Morgan R.;
- Gold, Sarah;
- Lasecka-Dykes, Lidia;
- Wright, Caroline;
- Ward, Joseph C.;
- McLean, Thomas C.;
- Forrest, Sophie;
- Jackson, Terry;
- Tuthill, Tobias J.;
- Rowlands, David J.;
- Stonehouse, Nicola J.
Publication type:
Article
Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes.
Published in:
PLoS Pathogens, 2017, v. 13, n. 2, p. 1, doi. 10.1371/journal.ppat.1006197
By:
- Groppelli, Elisabetta;
- Levy, Hazel C.;
- Sun, Eileen;
- Strauss, Mike;
- Nicol, Clare;
- Gold, Sarah;
- Zhuang, Xiaowei;
- Tuthill, Tobias J.;
- Hogle, James M.;
- Rowlands, David J.
Publication type:
Article
Hepatitis A virus and the origins of picornaviruses.
Published in:
Nature, 2015, v. 517, n. 7532, p. 85, doi. 10.1038/nature13806
By:
- Wang, Xiangxi;
- Ren, Jingshan;
- Gao, Qiang;
- Hu, Zhongyu;
- Sun, Yao;
- Li, Xuemei;
- Rowlands, David J.;
- Yin, Weidong;
- Wang, Junzhi;
- Stuart, David I.;
- Rao, Zihe;
- Fry, Elizabeth E.
Publication type:
Article
Plant-made polio type 3 stabilized VLPs--a candidate synthetic polio vaccine.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00090-w
By:
- Marsian, Johanna;
- Fox, Helen;
- Bahar, Mohammad W.;
- Kotecha, Abhay;
- Fry, Elizabeth E.;
- Stuart, David I.;
- Macadam, Andrew J.;
- Rowlands, David J.;
- Lomonossoff, George P.
Publication type:
Article
Virology Division News.
Published in:
2005
By:
- Mahy, Brian WJ;
- Rowlands, David J
Publication type:
Obituary
The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine
Published in:
FEBS Letters, 2003, v. 535, n. 1-3, p. 34, doi. 10.1016/S0014-5793(02)03851-6
By:
- Griffin, Stephen D.C.;
- Beales, Lucy P.;
- Clarke, Dean S.;
- Worsfold, Oliver;
- Evans, Stephen D.;
- Jaeger, Joachim;
- Harris, Mark P.G.;
- Rowlands, David J.
Publication type:
Article
Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts.
Published in:
PLoS Pathogens, 2020, v. 16, n. 12, p. 1, doi. 10.1371/journal.ppat.1009146
By:
- Chandler-Bostock, Rebecca;
- Mata, Carlos P.;
- Bingham, Richard J.;
- Dykeman, Eric C.;
- Meng, Bo;
- Tuthill, Tobias J.;
- Rowlands, David J.;
- Ranson, Neil A.;
- Twarock, Reidun;
- Stockley, Peter G.
Publication type:
Article
Publisher Correction: A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation.
Published in:
2022
By:
- Bahar, Mohammad W.;
- Nasta, Veronica;
- Fox, Helen;
- Sherry, Lee;
- Grehan, Keith;
- Porta, Claudine;
- Macadam, Andrew J.;
- Stonehouse, Nicola J.;
- Rowlands, David J.;
- Fry, Elizabeth E.;
- Stuart, David I.
Publication type:
Correction Notice
A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation.
Published in:
Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04252-5
By:
- Bahar, Mohammad W.;
- Nasta, Veronica;
- Fox, Helen;
- Sherry, Lee;
- Grehan, Keith;
- Porta, Claudine;
- Macadam, Andrew J.;
- Stonehouse, Nicola J.;
- Rowlands, David J.;
- Fry, Elizabeth E.;
- Stuart, David I.
Publication type:
Article
The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication, but essential for the production of infectious virus.
Published in:
PLoS Pathogens, 2022, v. 18, n. 6, p. 1, doi. 10.1371/journal.ppat.1010589
By:
- Ward, Joseph C.;
- Lasecka-Dykes, Lidia;
- Neil, Chris;
- Adeyemi, Oluwapelumi O.;
- Gold, Sarah;
- McLean-Pell, Niall;
- Wright, Caroline;
- Herod, Morgan R.;
- Kealy, David;
- Warner, Emma;
- Jackson, Terry;
- King, Donald P.;
- Tuthill, Tobias J.;
- Rowlands, David J.;
- Stonehouse, Nicola J.
Publication type:
Article

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