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The mighty mouse: genetically engineered mouse models in cancer drug development.
- Published in:
- Nature Reviews Drug Discovery, 2006, v. 5, n. 9, p. 741, doi. 10.1038/nrd2110
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- Publication type:
- Article
FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis.
- Published in:
- EMBO Molecular Medicine, 2018, v. 10, n. 2, p. 276, doi. 10.15252/emmm.201606261
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- Publication type:
- Article
Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells.
- Published in:
- 2003
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- Publication type:
- Letter
Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis.
- Published in:
- Nature Medicine, 2002, v. 8, n. 11, p. 1276, doi. 10.1038/nm787
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- Publication type:
- Article
Keeping telomerase in its place.
- Published in:
- Nature Medicine, 2002, v. 8, n. 9, p. 934, doi. 10.1038/nm0902-934
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- Publication type:
- Article
Mice without telomerase: what can they teach us about human cancer?
- Published in:
- Nature Medicine, 2000, v. 6, n. 8, p. 852, doi. 10.1038/78595
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- Publication type:
- Article
Decreased Cyclin-Dependent Kinase 5 (cdk5) Activity Is Accompanied by Redistribution of cdk5 and Cytoskeletal Proteins and Increased Cytoskeletal Protein Phosphorylation in p35 Null Mice.
- Published in:
- Journal of Neuroscience, 2003, v. 23, n. 33, p. 10633, doi. 10.1523/JNEUROSCI.23-33-10633.2003
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- Publication type:
- Article
FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 10, p. 1, doi. 10.1172/JCI64906
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- Publication type:
- Article
FOXO1 in the ventromedial hypothalamus regulates energy balance.
- Published in:
- Journal of Clinical Investigation, 2012, v. 122, n. 7, p. 2578, doi. 10.1172/JCI62848
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- Publication type:
- Article
The FoxO3/type 2 deiodinase pathway is required for normal mouse myogenesis and muscle regeneration.
- Published in:
- 2010
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- Publication type:
- journal article
FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice.
- Published in:
- 2010
- By:
- Publication type:
- journal article
A Foxo/Notch pathway controls myogenic differentiation and fiber type specification.
- Published in:
- 2007
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- Publication type:
- journal article
Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Activation of FoxO3a/Bim axis in patients with Primary Biliary Cirrhosis.
- Published in:
- Liver International, 2013, v. 33, n. 2, p. 231, doi. 10.1111/liv.12030
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- Publication type:
- Article
mTORC1 Promotes Denervation-Induced Muscle Atrophy Through a Mechanism Involving the Activation of FoxO and E3 Ubiquitin Ligases.
- Published in:
- Science Signaling, 2014, v. 7, n. 314, p. 1, doi. 10.1126/scisignal.2004809
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- Publication type:
- Article
Tailor-Made Monoclonal Antibodies.
- Published in:
- Annals of Internal Medicine, 1986, v. 104, n. 2, p. 225, doi. 10.7326/0003-4819-104-2-225
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- Publication type:
- Article
Chimeric mouse tumor models reveal differences in pathway activation between ERBB family– and KRAS-dependent lung adenocarcinomas.
- Published in:
- Nature Biotechnology, 2010, v. 28, n. 1, p. 71, doi. 10.1038/nbt.1595
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- Publication type:
- Article
Sin3a Is Required by Sertoli Cells to Establish a Niche for Undifferentiated Spermatogonia, Germ Cell Tumors, and Spermatid Elongation.
- Published in:
- Stem Cells, 2010, v. 28, n. 8, p. 1424, doi. 10.1002/stem.464
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- Publication type:
- Article
Foxo1 integrates insulin signaling with mitochondrial function in the liver.
- Published in:
- Nature Medicine, 2009, v. 15, n. 11, p. 1307, doi. 10.1038/nm.2049
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- Publication type:
- Article
The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake.
- Published in:
- Nature Medicine, 2009, v. 15, n. 10, p. 1195, doi. 10.1038/nm.2026
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- Publication type:
- Article
Generation of functional insulin-producing cells in the gut by Foxo1 ablation.
- Published in:
- Nature Genetics, 2012, v. 44, n. 4, p. 406, doi. 10.1038/ng.2215
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- Publication type:
- Article
Braf<sup>V600E</sup> cooperates with Pten loss to induce metastatic melanoma.
- Published in:
- Nature Genetics, 2009, v. 41, n. 5, p. 544, doi. 10.1038/ng.356
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- Publication type:
- Article
LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis.
- Published in:
- Nature Genetics, 2008, v. 40, n. 4, p. 455, doi. 10.1038/ng.98
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- Publication type:
- Article
Cancer chromosomes in crisis.
- Published in:
- Nature Genetics, 2004, v. 36, n. 9, p. 932, doi. 10.1038/ng0904-932
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- Publication type:
- Article
Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
- Published in:
- Nature Genetics, 2004, v. 36, n. 8, p. 877, doi. 10.1038/ng1389
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- Publication type:
- Article
Conquering the complexity of p53.
- Published in:
- Nature Genetics, 2004, v. 36, n. 1, p. 7, doi. 10.1038/ng0104-7
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- Publication type:
- Article
Genome-wide retroviral insertional tagging of genes involved in cancer in Cdkn2a-deficient mice.
- Published in:
- Nature Genetics, 2002, v. 32, n. 1, p. 160, doi. 10.1038/ng956
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- Publication type:
- Article
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans.
- Published in:
- Nature Genetics, 2001, v. 28, n. 2, p. 155, doi. 10.1038/88871
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- Publication type:
- Article
Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation.
- Published in:
- Nature Genetics, 2000, v. 26, n. 1, p. 85, doi. 10.1038/79232
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- Publication type:
- Article
Gene-target recognition among members of the Myc superfamily and implications for oncogenesis.
- Published in:
- Nature Genetics, 2000, v. 24, n. 2, p. 113, doi. 10.1038/72761
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- Publication type:
- Article
Identification of differentially regulated gene targets in the Myc and Mad family proteins.
- Published in:
- 1999
- By:
- Publication type:
- Abstract
A bumper crop of cancer genes.
- Published in:
- Nature Genetics, 1999, v. 23, n. 3, p. 253, doi. 10.1038/15423
- By:
- Publication type:
- Article
Coxsackievirus and adenovirus receptor is essential for cardiomyocyte development.
- Published in:
- Genesis: The Journal of Genetics & Development, 2005, v. 42, n. 2, p. 77, doi. 10.1002/gene.20127
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- Publication type:
- Article
Axis of ageing: telomeres, p53 and mitochondria.
- Published in:
- Nature Reviews Molecular Cell Biology, 2012, v. 13, n. 6, p. 397, doi. 10.1038/nrm3352
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- Publication type:
- Article
How stem cells age and why this makes us grow old.
- Published in:
- Nature Reviews Molecular Cell Biology, 2007, v. 8, n. 9, p. 703, doi. 10.1038/nrm2241
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- Publication type:
- Article
Deletion of Hepatic FoxO1/3/4 Genes in Mice Significantly Impacts on Glucose Metabolism through Downregulation of Gluconeogenesis and Upregulation of Glycolysis.
- Published in:
- PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0074340
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- Publication type:
- Article
Transcription Factor FoxO1 Is Essential for Enamel Biomineralization.
- Published in:
- PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030357
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- Publication type:
- Article
Targeting EGFR Induced Oxidative Stress by PARP1 Inhibition in Glioblastoma Therapy.
- Published in:
- PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010767
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- Publication type:
- Article
Stromal biology of pancreatic cancer.
- Published in:
- Journal of Cellular Biochemistry, 2007, v. 101, n. 4, p. 887, doi. 10.1002/jcb.21209
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- Publication type:
- Article
A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes.
- Published in:
- Nature, 1986, v. 322, n. 6075, p. 179, doi. 10.1038/322179a0
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- Publication type:
- Article
Human N-myc is closely related in organization and nucleotide sequence to c-myc.
- Published in:
- Nature, 1986, v. 319, n. 6048, p. 73, doi. 10.1038/319073a0
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- Publication type:
- Article
Impaired Processing of DNA Photoproducts and Ultraviolet Hypermutability With Loss of p16<sup>INK4a</sup> or p19<sup>ARF</sup>.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2004, v. 96, n. 23, p. 1790, doi. 10.1093/jnci/djh307
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- Publication type:
- Article
Walking the Telomere Plank Into Cancer.
- Published in:
- 2003
- By:
- Publication type:
- Editorial
p16(Ink4a) in melanocyte senescence and differentiation.
- Published in:
- 2002
- By:
- Publication type:
- journal article
P16[sup Ink4a] in Melanocyte Senescence and Differentiation.
- Published in:
- JNCI: Journal of the National Cancer Institute, 2002, v. 94, n. 6, p. 446, doi. 10.1093/jnci/94.6.446
- By:
- Publication type:
- Article
The differential impact of p16<sup>INK4a</sup> or p19<sup>ARF</sup> deficiency on cell growth and tumorigenesis.
- Published in:
- Oncogene, 2004, v. 23, n. 2, p. 379, doi. 10.1038/sj.onc.1207074
- By:
- Publication type:
- Article
A strong candidate gene for the Papg1 locus on mouse chromosome 4 affecting lung tumor progression.
- Published in:
- Oncogene, 2002, v. 21, n. 38, p. 5960, doi. 10.1038/sj.onc.1205725
- By:
- Publication type:
- Article
SUMOylation of ROR-γt inhibits IL-17 expression and inflammation via HDAC2.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06924-5
- By:
- Publication type:
- Article
Identification of Blood-Based Biomarkers for the Prediction of the Response to Neoadjuvant Chemoradiation in Rectal Cancer.
- Published in:
- Cancers, 2021, v. 13, n. 14, p. 3642, doi. 10.3390/cancers13143642
- By:
- Publication type:
- Article
Overlapping functions of Hdac1 and Hdac2 in cell cycle regulation and haematopoiesis.
- Published in:
- EMBO Journal, 2010, v. 29, n. 15, p. 2586, doi. 10.1038/emboj.2010.136
- By:
- Publication type:
- Article