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Experimental pharmacology in precision medicine.
- Published in:
- Pharmacology Research & Perspectives, 2023, v. 11, n. 6, p. 1, doi. 10.1002/prp2.1147
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- Publication type:
- Article
Preface to Special Issue on 'Cytochrome P450 Variation in Pharmacogenomics'.
- Published in:
- 2018
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- Publication type:
- Editorial
Pharmacogenomics of CYP2C9: Functional and Clinical Considerations.
- Published in:
- Journal of Personalized Medicine, 2018, v. 8, n. 1, p. 1, doi. 10.3390/jpm8010001
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- Publication type:
- Article
Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-like Effects, in Healthy Adult Participants.
- Published in:
- Pharmaceutics, 2022, v. 14, n. 3, p. 620, doi. 10.3390/pharmaceutics14030620
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- Publication type:
- Article
Association Between CYP2C9 Genetic Variants and Anticoagulation-Related Outcomes During Warfarin Therapy.
- Published in:
- JAMA: Journal of the American Medical Association, 2002, v. 287, n. 13, p. 1690, doi. 10.1001/jama.287.13.1690
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- Publication type:
- Article
Spotlight on CYP4B1.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2038, doi. 10.3390/ijms24032038
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- Publication type:
- Article
Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol.
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- Biochemical Journal, 2015, v. 465, n. 1, p. 103, doi. 10.1042/BJ20140813
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- Publication type:
- Article
Localization of CYP4B1 in the rat nasal cavity and analysis of CYPs as secreted proteins.
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- Journal of Biochemical & Molecular Toxicology, 2006, v. 20, n. 3, p. 139, doi. 10.1002/jbt.20123
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- Publication type:
- Article
Characterization of an Additional Splice Acceptor Site Introduced into CYP4B1 in Hominoidae during Evolution.
- Published in:
- PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0137110
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- Publication type:
- Article
Human Valacyclovir Hydrolase/Biphenyl Hydrolase-Like Protein Is a Highly Efficient Homocysteine Thiolactonase.
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- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0110054
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- Publication type:
- Article
Structure-Activity Relationships of Benzbromarone Metabolites and Derivatives as EYA Inhibitory Anti-Angiogenic Agents.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084582
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- Publication type:
- Article
CYP2C9 haplotype structure in European American warfarin patients and association with clinical outcomes.
- Published in:
- Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 5, p. 353, doi. 10.1016/j.clpt.2005.01.019
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- Publication type:
- Article
Cytochrome P450 2C8: Substrates, inhibitors, harmacogenetics, and clinical relevance.
- Published in:
- Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 5, p. 341, doi. 10.1016/j.clpt.2004.12.267
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- Publication type:
- Article
Cytochrome P4502C9 activity in end-stage renal disease<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 2003, v. 73, n. 5, p. 475, doi. 10.1016/S0009-9236(03)00015-8
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- Publication type:
- Article
Inhibition of human liver microsomal epoxide hydrolase by valproate and valpromide: In vitro/in vivo correlation.
- Published in:
- Clinical Pharmacology & Therapeutics, 1989, v. 46, n. 1, p. 82, doi. 10.1038/clpt.1989.110
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- Publication type:
- Article
The Prevalence of CYP2C8, 2C9, 2J2, and Soluble Epoxide Hydrolase Polymorphisms in African Americans With Hypertension
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- American Journal of Hypertension, 2005, v. 18, n. 10, p. 1276, doi. 10.1016/j.amjhyper.2005.04.019
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- Publication type:
- Article
Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom.
- Published in:
- Clinical Pharmacology & Therapeutics, 2023, v. 113, n. 6, p. 1315, doi. 10.1002/cpt.2891
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- Publication type:
- Article
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA‐B Genotypes and Phenytoin Dosing: 2020 Update.
- Published in:
- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 2, p. 302, doi. 10.1002/cpt.2008
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- Publication type:
- Article
Applying Multiplex Assays to Understand Variation in Pharmacogenes.
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- Clinical Pharmacology & Therapeutics, 2019, v. 106, n. 2, p. 290, doi. 10.1002/cpt.1468
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- Publication type:
- Article
Mutation of the conserved I-helix threonine in CYP2C9 eliminates heteroactivation.
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- FASEB Journal, 2007, v. 21, n. 6, p. A1185
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- Publication type:
- Article
Novel Hispanic American CYP2C9 Genetic Variants and Assessment of Their Impact on Gene Expression.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A415
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- Publication type:
- Article
A case study of acenocoumarol sensitivity and genotype-phenotype discordancy explained by combinations of polymorphisms in VKORC1 and CYP2C9.
- Published in:
- British Journal of Clinical Pharmacology, 2006, v. 62, n. 5, p. 617, doi. 10.1111/j.1365-2125.2006.02688.x
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- Publication type:
- Article
In vitro evaluation of potentialin vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms.
- Published in:
- British Journal of Clinical Pharmacology, 2000, v. 50, n. 4, p. 311, doi. 10.1046/j.1365-2125.2000.00265.x
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- Publication type:
- Article
Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients.
- Published in:
- PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161074
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- Publication type:
- Article
CYP2C9 Genotype-Dependent Warfarin Pharmacokinetics: Impact of CYP2C9 Genotype on R- and S-Warfarin and Their Oxidative Metabolites.
- Published in:
- Journal of Clinical Pharmacology, 2017, v. 57, n. 3, p. 382, doi. 10.1002/jcph.813
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- Publication type:
- Article
Effects of Oral Vitamin K on S-and R-Warfarin Pharmacokinetics and Pharmacodynamics: Enhanced Safety of Warfarin as a CYP2C9 Probe.
- Published in:
- Journal of Clinical Pharmacology, 2001, v. 41, n. 7, p. 715, doi. 10.1177/009127000104100703
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- Publication type:
- Article
Ligand characterization of CYP4B1 isoforms modified for high-level expression in Escherichia coli and HepG2 cells.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2017, v. 30, n. 3, p. 205, doi. 10.1093/protein/gzw075
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- Publication type:
- Article
Adapting regulatory drug‐drug interaction guidance to design clinical pharmacokinetic natural product‐drug interaction studies: A NaPDI Center recommended approach.
- Published in:
- CTS: Clinical & Translational Science, 2022, v. 15, n. 2, p. 322, doi. 10.1111/cts.13172
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- Publication type:
- Article
Associations of CYP2C9 and CYP2C19 Pharmacogenetic Variation with Phenytoin‐Induced Cutaneous Adverse Drug Reactions.
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- CTS: Clinical & Translational Science, 2020, v. 13, n. 5, p. 1004, doi. 10.1111/cts.12787
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- Publication type:
- Article
A Novel LC‐MS/MS Assay for Quantification of Des‐carboxy Prothrombin and Characterization of Warfarin‐Induced Changes.
- Published in:
- CTS: Clinical & Translational Science, 2020, v. 13, n. 4, p. 718, doi. 10.1111/cts.12757
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- Publication type:
- Article
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity.
- Published in:
- CTS: Clinical & Translational Science, 2020, v. 13, n. 1, p. 147, doi. 10.1111/cts.12695
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- Publication type:
- Article
VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People.
- Published in:
- CTS: Clinical & Translational Science, 2019, v. 12, n. 3, p. 312, doi. 10.1111/cts.12611
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- Publication type:
- Article
Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue.
- Published in:
- PLoS Genetics, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pgen.1002078
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- Publication type:
- Article
Chemical synthesis, absolute configuration, and stereochemistry of formation of 10-hydroxywarfarin: A major oxidative metabolite of (+)-(r)-warfarin from hepatic microsomal preparations.
- Published in:
- Chirality, 1990, v. 2, n. 2, p. 96, doi. 10.1002/chir.530020207
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- Publication type:
- Article
Dietary Vitamin K and Association with Hepatic Vitamin K Status in a Yup'ik Study Population from Southwestern Alaska.
- Published in:
- Molecular Nutrition & Food Research, 2018, v. 62, n. 3, p. 1, doi. 10.1002/mnfr.201700746
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- Publication type:
- Article
ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.
- Published in:
- Molecular Nutrition & Food Research, 2013, v. 57, n. 10, p. 1785, doi. 10.1002/mnfr.201200797
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- Publication type:
- Article
Interaction of amiodarone with racemic warfarin and its separated enantiomorphs in humans.
- Published in:
- Clinical Pharmacology & Therapeutics, 1987, v. 42, n. 3, p. 290, doi. 10.1038/clpt.1987.149
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- Publication type:
- Article
Valproate hydroxylation by human fetal tissues and embryotoxicity of metabolites.
- Published in:
- Clinical Pharmacology & Therapeutics, 1986, v. 40, n. 2, p. 172, doi. 10.1038/clpt.1986.160
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- Publication type:
- Article
Generation and Characterization of a Cyp4b1 Null Mouse and the Role of CYP4B1 in the Activation and Toxicity of Ipomeanol.
- Published in:
- Toxicological Sciences, 2013, v. 134, n. 2, p. 243, doi. 10.1093/toxsci/kft123
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- Publication type:
- Article
Dietary and genetic influences on hemostasis in a Yup’ik Alaska Native population.
- Published in:
- PLoS ONE, 2017, v. 12, n. 4, p. 1, doi. 10.1371/journal.pone.0173616
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- Publication type:
- Article