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A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models.
Published in:
PLoS Biology, 2022, v. 20, n. 5, p. 1, doi. 10.1371/journal.pbio.3001624
By:
- Singh, Dharaminder;
- Deosarkar, Sudhir P.;
- Cadogan, Elaine;
- Flemington, Vikki;
- Bray, Alysha;
- Zhang, Jingwen;
- Reiserer, Ronald S.;
- Schaffer, David K.;
- Gerken, Gregory B.;
- Britt, Clayton M.;
- Werner, Erik M.;
- Gibbons, Francis D.;
- Kostrzewski, Tomasz;
- Chambers, Christopher E.;
- Davies, Emma J.;
- Montoya, Antonio Ramos;
- Fok, Jacqueline H. L.;
- Hughes, David;
- Fabre, Kristin;
- Wagoner, Matthew P.
Publication type:
Article
Contractile and Genetic Characterization of Cardiac Constructs Engineered from Human Induced Pluripotent Stem Cells: Modeling of Tuberous Sclerosis Complex and the Effects of Rapamycin.
Published in:
Bioengineering (Basel), 2024, v. 11, n. 3, p. 234, doi. 10.3390/bioengineering11030234
By:
- Sidorov, Veniamin Y.;
- Sidorova, Tatiana N.;
- Samson, Philip C.;
- Reiserer, Ronald S.;
- Britt, Clayton M.;
- Neely, M. Diana;
- Ess, Kevin C.;
- Wikswo, John P.
Publication type:
Article
Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit.
Published in:
Journal of Neuroinflammation, 2016, v. 13, p. 1, doi. 10.1186/s12974-016-0760-y
By:
- Brown, Jacquelyn A.;
- Codreanu, Simona G.;
- Shi, Mingjian;
- Sherrod, Stacy D.;
- Markov, Dmitry A.;
- Neely, M. Diana;
- Britt, Clayton M.;
- Hoilett, Orlando S.;
- Reiserer, Ronald S.;
- Samson, Philip C.;
- McCawley, Lisa J.;
- Webb, Donna J.;
- Bowman, Aaron B.;
- McLean, John A.;
- Wikswo, John P.
Publication type:
Article

Found: 3

A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models.

Contractile and Genetic Characterization of Cardiac Constructs Engineered from Human Induced Pluripotent Stem Cells: Modeling of Tuberous Sclerosis Complex and the Effects of Rapamycin.

Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit.