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Neurofibromin, the Neurofibromatosis Type 1 Ras-GAP, Is Required for Appropriate P<sub>0</sub> Expression and Myelination.
- Published in:
- Annals of the New York Academy of Sciences, 1999, v. 883, n. 1, p. 203, doi. 10.1111/j.1749-6632.1999.tb08583.x
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- Article
C5aR plus MEK inhibition durably targets the tumor milieu and reveals tumor cell phagocytosis.
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- Life Science Alliance, 2024, v. 7, n. 5, p. 1, doi. 10.26508/lsa.202302229
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- Publication type:
- Article
The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.
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- Oncogene, 2001, v. 20, n. 1, p. 97, doi. 10.1038/sj.onc.1204026
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- Article
Overexpression of activated neu/erbB2 initiates immortalization and malignant transformation of immature Schwann cells in vitro.
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- Oncogene, 1999, v. 18, n. 48, p. 6692, doi. 10.1038/sj.onc.1203055
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- Article
Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells.
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- Oncogene, 1998, v. 17, n. 17, p. 2195, doi. 10.1038/sj.onc.1202141
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- Article
Racl Controls Schwann Cell Myelination through cAMP and NF2/merlin.
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- Journal of Neuroscience, 2012, v. 32, n. 48, p. 17251, doi. 10.1523/JNEUROSCI.2461-12.2012
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- Article
Neurofibromatosis Type 1: Modeling CNS Dysfunction.
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- Journal of Neuroscience, 2012, v. 32, n. 41, p. 14087, doi. 10.1523/JNEUROSCI.3242-12.2012
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- Article
Genome-wide Twist1 occupancy in endocardial cushion cells, embryonic limb buds, and peripheral nerve sheath tumor cells.
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- BMC Genomics, 2014, v. 15, n. 1, p. 821, doi. 10.1186/1471-2164-15-821
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- Article
Corrigendum: Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors.
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- Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1456897
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- Article
Myelomodulatory treatments augment the therapeutic benefit of oncolytic viroimmunotherapy in murine models of malignant peripheral nerve sheath tumors.
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- Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1384623
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- Publication type:
- Article
Corrigendum: The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism.
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- Nature Communications, 2015, v. 6, n. 1, p. 6075, doi. 10.1038/ncomms7075
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- Article
The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism.
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- Nature Communications, 2014, v. 5, n. 9, p. 4993, doi. 10.1038/ncomms5993
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- Article
Proximity biotinylation identifies a set ofconformation-specific interactions between Merlin and cell junction proteins.
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- Science Signaling, 2019, v. 12, n. 578, p. N.PAG, doi. 10.1126/scisignal.aau8749
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- Article
cAMP-dependent protein kinase A is required for Schwann cell growth: Interactions between the cAMP and neuregulin/tyrosine kinase pathways.
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- Journal of Neuroscience Research, 1997, v. 49, n. 2, p. 236, doi. 10.1002/(SICI)1097-4547(19970715)49:2<236::AID-JNR12>3.0.CO;2-Z
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- Article
Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.
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- 2012
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- Journal Article
Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.
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- Sarcoma, 2012, p. 1, doi. 10.1155/2012/620834
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- Article
The "neuro" of neuroblastoma: Neuroblastoma as a neurodevelopmental disorder.
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- 2016
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- Publication type:
- journal article
NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.
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- Acta Neuropathologica, 2020, v. 139, n. 1, p. 157, doi. 10.1007/s00401-019-02086-w
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- Article
Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition.
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- Acta Neuropathologica, 2013, v. 125, n. 1, p. 159, doi. 10.1007/s00401-012-1056-7
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- Article
Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1.
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- Communications Biology, 2018, v. 1, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0163-y
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- Article
Role of TC21/R-Ras2 in enhanced migration of neurofibromin-deficient Schwann cells.
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- Oncogene, 2004, v. 23, n. 2, p. 368, doi. 10.1038/sj.onc.1207075
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- Publication type:
- Article
The Neurofibromatosis Type 1 (Nf1) Tumor Suppressor is a Modifier of Carcinogen-Induced Pigmentation and Papilloma Formation in C57BL/6 Mice.
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- Journal of Investigative Dermatology, 2000, v. 114, n. 6, p. 1093, doi. 10.1046/j.1523-1747.2000.00994.x
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- Article
The Nf1 Tumor Suppressor Regulates Mouse Skin Wound Healing, Fibroblast Proliferation, and Collagen Deposited by Fibroblasts.
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- Journal of Investigative Dermatology, 1999, v. 112, n. 6, p. 835, doi. 10.1046/j.1523-1747.1999.00609.x
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- Publication type:
- Article
Localization of Neurofibromin to Keratinocytes and Melanocytes in Developing Rat and Human Skin.
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- Journal of Investigative Dermatology, 1994, v. 102, n. 5, p. 812, doi. 10.1111/1523-1747.ep12379925
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- Article
Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis.
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- Nature Genetics, 2013, v. 45, n. 7, p. 756, doi. 10.1038/ng.2641
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- Article
Oncolytic HSV and Erlotinib Inhibit Tumor Growth and Angiogenesis in a Novel Malignant Peripheral Nerve Sheath Tumor Xenograft Model.
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- Molecular Therapy, 2007, v. 15, n. 2, p. 279, doi. 10.1038/sj.mt.6300038
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- Publication type:
- Article
658. Oncolytic Herpes Virus Mutants Are Efficacious Against Malignant Peripheral Nerve Sheath Tumor Xenografts.
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- Molecular Therapy, 2006, v. 13, p. S253, doi. 10.1016/j.ymthe.2006.08.734
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- Publication type:
- Article
Neurofibromatosis Type 1-Associated MPNST State of the Science: Outlining a Research Agenda for the Future.
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- 2017
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- Publication type:
- journal article
Defective transcription elongation in a subset of cancers confers immunotherapy resistance.
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- Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06810-0
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- Article
Merlin tumor suppressor function is regulated by PIP<sub>2</sub>-mediated dimerization.
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- PLoS ONE, 2023, v. 17, n. 2, p. 1, doi. 10.1371/journal.pone.0281876
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- Article
Neurofibromatosis in the Era of Precision Medicine: Development of MEK Inhibitors and Recent Successes with Selumetinib.
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- Current Oncology Reports, 2021, v. 23, n. 4, p. 1, doi. 10.1007/s11912-021-01032-y
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- Article
The Protein Tyrosine Phosphatase Shp2 Is Required for the Generation of Oligodendrocyte Progenitor Cells and Myelination in the Mouse Telencephalon.
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- Journal of Neuroscience, 2014, v. 34, n. 10, p. 3767, doi. 10.1523/JNEUROSCI.3515-13.2014
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- Publication type:
- Article
The Protein Kinase A Regulatory Subunit R1A (Prkar1a) Plays Critical Roles in Peripheral Nerve Development.
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- Journal of Neuroscience, 2013, v. 33, n. 46, p. 17967, doi. 10.1523/JNEUROSCI.0766-13.2013
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- Article
HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat.
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- Journal of Pathology: Clinical Research, 2016, v. 2, n. 2, p. 59, doi. 10.1002/cjp2.35
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- Article
Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-56247-8
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- Article
Integrative genomic analyses of neurofibromatosis tumours identify SOX9 as a biomarker and survival gene.
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- EMBO Molecular Medicine, 2009, v. 1, n. 4, p. 236, doi. 10.1002/emmm.200900027
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- Article
Neuroblastoma Cell Lines Contain Pluripotent Tumor Initiating Cells That Are Susceptible to a Targeted Oncolytic Virus.
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- PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004235
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- Article
Malignant peripheral nerve sheath tumor: Transformation in a patient with neurofibromatosis type 2.
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- 2019
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- Publication type:
- journal article
Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.
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- Pediatric Blood & Cancer, 2015, v. 62, n. 10, p. 1709, doi. 10.1002/pbc.25546
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- Publication type:
- Article
Preclincial testing of Sorafenib and RAD001 in the Nf<sup> flox/flox</sup> ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging.
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- Pediatric Blood & Cancer, 2012, v. 58, n. 2, p. 173, doi. 10.1002/pbc.23015
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- Publication type:
- Article
Purinergic signaling in peripheral nervous system glial cells.
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- Glia, 2021, v. 69, n. 8, p. 1837, doi. 10.1002/glia.23969
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- Publication type:
- Article
Oligodendrocyte RasG12V expressed in its endogenous locus disrupts myelin structure through increased MAPK, nitric oxide, and notch signaling.
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- Glia, 2017, v. 65, n. 12, p. 1990, doi. 10.1002/glia.23209
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- Article
Cdc42 regulates schwann cell radial sorting and myelin sheath folding through NF2/merlin-dependent and independent signaling.
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- Glia, 2013, v. 61, n. 11, p. 1906, doi. 10.1002/glia.22567
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- Article
Aspects of the ecology of wood turtles, Clemmys insculpta, in Wisconsin
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- Canadian Field-Naturalist, 1991, v. 105, n. 3, p. 363, doi. 10.5962/p.358045
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- Article
An inflammatory gene signature distinguishes neurofibroma Schwann cells and macrophages from cells in the normal peripheral nervous system.
- Published in:
- Scientific Reports, 2017, p. 43315, doi. 10.1038/srep43315
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- Publication type:
- Article
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility.
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- EMBO Journal, 2002, v. 21, n. 3, p. 281, doi. 10.1093/emboj/21.3.281
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- Article
Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13.
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- 2016
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- Publication type:
- journal article
MEK inhibitio n exhibits efficacy in human and mouse neurofibromatosis tumors.
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- Journal of Clinical Investigation, 2013, v. 123, n. 1, p. 340, doi. 10.1172/JCI60578
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- Article
How does the Schwann cell lineage form tumors in NF1?
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- Glia, 2008, v. 56, n. 14, p. 1590, doi. 10.1002/glia.20776
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- Article
Regulation of neurofibromin expression in rat sciatic nerve and cultured Schwann cells.
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- Glia, 1995, v. 15, n. 1, p. 22, doi. 10.1002/glia.440150104
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- Article