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SARS-CoV-2 S protein: ACE2 interaction reveals novel allosteric targets.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.63646
By:
- Raghuvamsi, Palur V.;
- Tulsian, Nikhil K.;
- Samsudin, Firdaus;
- Xinlei Qian;
- Purushotorman, Kiren;
- Gu Yue;
- Kozma, Mary M.;
- Hwa, Wong Y.;
- Lescar, Julien;
- Bond, Peter J.;
- MacAry, Paul A.;
- Anand, Ganesh S.
Publication type:
Article
Defining neutralization and allostery by antibodies against COVID-19 variants.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42408-x
By:
- Tulsian, Nikhil Kumar;
- Palur, Raghuvamsi Venkata;
- Qian, Xinlei;
- Gu, Yue;
- D/O Shunmuganathan, Bhuvaneshwari;
- Samsudin, Firdaus;
- Wong, Yee Hwa;
- Lin, Jianqing;
- Purushotorman, Kiren;
- Kozma, Mary McQueen;
- Wang, Bei;
- Lescar, Julien;
- Wang, Cheng-I;
- Gupta, Ravindra Kumar;
- Bond, Peter John;
- MacAry, Paul Anthony
Publication type:
Article
Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-08790-1
By:
- Gu, Yue;
- Wong, Yee Hwa;
- Liew, Chong Wai;
- Chan, Conrad E. Z.;
- Murali, Tanusya M.;
- Yap, Jiawei;
- Too, Chien Tei;
- Purushotorman, Kiren;
- Hamidinia, Maryam;
- El Sahili, Abbas;
- Goh, Angeline T. H.;
- Teo, Rachel Z. C.;
- Wood, Kathryn J.;
- Hanson, Brendon J.;
- Gascoigne, Nicholas R. J.;
- Lescar, Julien;
- Vathsala, Anantharaman;
- MacAry, Paul A.
Publication type:
Article
The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeutic efficacy of the antibody.
Published in:
PLoS ONE, 2021, v. 16, n. 6, p. 1, doi. 10.1371/journal.pone.0253487
By:
- Chan, Conrad E. Z.;
- Seah, Shirley G. K.;
- Chye, De Hoe;
- Massey, Shane;
- Torres, Maricela;
- Lim, Angeline P. C.;
- Wong, Steven K. K.;
- Neo, Jacklyn J. Y.;
- Wong, Pui San;
- Lim, Jie Hui;
- Loh, Gary S. L.;
- Wang, Dongling;
- Boyd-Kirkup, Jerome D.;
- Guan, Siyu;
- Thakkar, Dipti;
- Teo, Guo Hui;
- Purushotorman, Kiren;
- Hutchinson, Paul E.;
- Young, Barnaby E.;
- Low, Jenny G.
Publication type:
Article
Durable cross-protective neutralizing antibody responses elicited by lipid nanoparticle-formulated SARS-CoV-2 mRNA vaccines.
Published in:
NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00835-x
By:
- Bae, Ki Hyun;
- Shunmuganathan, Bhuvaneshwari;
- Zhang, Li;
- Lim, Andrew;
- Gupta, Rashi;
- Wang, Yanming;
- Chua, Boon Lin;
- Wang, Yang;
- Gu, Yue;
- Qian, Xinlei;
- Tan, Isabelle Siang Ling;
- Purushotorman, Kiren;
- MacAry, Paul A.;
- White, Kevin P.;
- Yang, Yi Yan
Publication type:
Article
An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis.
Published in:
NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00710-1
By:
- Krishnananthasivam, Shivankari;
- Li, Hao;
- Bouzeyen, Rania;
- Shunmuganathan, Bhuvaneshwari;
- Purushotorman, Kiren;
- Liao, Xinlei;
- Du, Fengjiao;
- Friis, Claudia Guldager Kring;
- Crawshay-Williams, Felicity;
- Boon, Low Heng;
- Xinlei, Qian;
- Chan, Conrad En Zuo;
- Sobota, Radoslaw;
- Kozma, Mary;
- Barcelli, Valeria;
- Wang, Guirong;
- Huang, Hairong;
- Floto, Andreas;
- Bifani, Pablo;
- Javid, Babak
Publication type:
Article
Author Correction: An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis.
Published in:
2023
By:
- Krishnananthasivam, Shivankari;
- Li, Hao;
- Bouzeyen, Rania;
- Shunmuganathan, Bhuvaneshwari;
- Purushotorman, Kiren;
- Liao, Xinlei;
- Du, Fengjiao;
- Friis, Claudia Guldager Kring;
- Crawshay-Williams, Felicity;
- Boon, Low Heng;
- Xinlei, Qian;
- Chan, Conrad En Zuo;
- Sobota, Radoslaw;
- Kozma, Mary;
- Barcelli, Valeria;
- Wang, Guirong;
- Huang, Hairong;
- Floto, Andreas;
- Bifani, Pablo;
- Javid, Babak
Publication type:
Correction Notice
An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis.
Published in:
NPJ Vaccines, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41541-023-00710-1
By:
- Krishnananthasivam, Shivankari;
- Li, Hao;
- Bouzeyen, Rania;
- Shunmuganathan, Bhuvaneshwari;
- Purushotorman, Kiren;
- Liao, Xinlei;
- Du, Fengjiao;
- Friis, Claudia Guldager Kring;
- Crawshay-Williams, Felicity;
- Boon, Low Heng;
- Xinlei, Qian;
- Chan, Conrad En Zuo;
- Sobota, Radoslaw;
- Kozma, Mary;
- Jo, Valeria Barcelli;
- Wang, Guirong;
- Huang, Hairong;
- Floto, Andreas;
- Bifani, Pablo;
- Javid, Babak
Publication type:
Article
Defining the specificity and function of a human neutralizing antibody for Hepatitis B virus.
Published in:
NPJ Vaccines, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41541-022-00516-7
By:
- Jhajharia, Saket;
- Lai, Fritz;
- Low, Heng Boon;
- Purushotorman, Kiren;
- Shunmuganathan, Bhuvaneshwari D/O;
- Chan, Conrad En Zuo;
- Hammond, Rachel;
- Netter, Hans-Jürgen;
- Chen, Qingfeng;
- Lim, Seng Gee;
- MacAry, Paul A.
Publication type:
Article
Switching Heavy Chain Constant Domains Denatures the Paratope 3D Architecture of Influenza Monoclonal Antibodies.
Published in:
Pathogens, 2023, v. 12, n. 1, p. 51, doi. 10.3390/pathogens12010051
By:
- Malisheni, Moffat M.;
- Chong, Cheng-Shoong;
- Murali, Tanusya M.;
- Purushotorman, Kiren;
- Qian, Xinlei;
- Laiman, Alfred;
- Tan, Yee-Joo;
- MacAry, Paul A.
Publication type:
Article
Relative deficiency in interferon‐γ‐secreting CD4+ T cells is strongly associated with poorer COVID‐19 vaccination responses in older adults.
Published in:
Aging Cell, 2024, v. 23, n. 4, p. 1, doi. 10.1111/acel.14099
By:
- Ho, Vanda W. T.;
- Boon, Low Heng;
- Cui, Jianzhou;
- Juequn, Zhou;
- Shunmuganathan, Bhuvaneshwari;
- Gupta, Rashi;
- Tan, Nikki Y. J.;
- Qian, Xinlei;
- Purushotorman, Kiren;
- Amrun, Siti Naqiah;
- Goh, Yun‐Shan;
- Tay, Matthew Zi‐Rui;
- Rouers, Angeline;
- Chang, Zi Wei;
- Yeo, Nicholas Kim‐Wah;
- Chan, Yi‐Hao;
- Hor, Pei Xian;
- Loh, Chiew Yee;
- Yang, Yuling;
- Torres Ruesta, Anthony
Publication type:
Article
Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-49231-w
By:
- Gu, Yue;
- Shunmuganathan, Bhuvaneshwari;
- Qian, Xinlei;
- Gupta, Rashi;
- Tan, Rebecca S. W.;
- Kozma, Mary;
- Purushotorman, Kiren;
- Murali, Tanusya M.;
- Tan, Nikki Y. J.;
- Preiser, Peter R.;
- Lescar, Julien;
- Nasir, Haziq;
- Somani, Jyoti;
- Tambyah, Paul A.;
- Fong, Siew-Wai;
- Amrun, Siti Naqiah;
- Goh, Yun-Shan;
- Tay, Matthew Zi-Rui;
- Rouers, Angeline;
- Chang, Zi Wei
Publication type:
Article

Found: 12