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Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice.
- Published in:
- 2014
- By:
- Publication type:
- journal article
Targeted p16<sup>Ink4a</sup> epimutation causes tumorigenesis and reduces survival in mice.
- Published in:
- Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3708, doi. 10.1172/JCI76507
- By:
- Publication type:
- Article
The cyclin-dependent kinase inhibitor p57(Kip2) mediates proliferative actions of PTHrP in chondrocytes.
- Published in:
- 2004
- By:
- Publication type:
- journal article
The cyclin-dependent kinase inhibitor p57<sup>Kip2</sup> mediates proliferative actions of PTHrP in chondrocytes.
- Published in:
- Journal of Clinical Investigation, 2004, v. 113, n. 9, p. 1334, doi. 10.1172/JCI200421252
- By:
- Publication type:
- Article
Preclinical testing of CT1113, a novel USP28 inhibitor, for the treatment of T‐cell acute lymphoblastic leukaemia.
- Published in:
- British Journal of Haematology, 2024, v. 204, n. 6, p. 2301, doi. 10.1111/bjh.19492
- By:
- Publication type:
- Article
Towards genetic genome projects: genomic library screening and gene-targeting vector construction in a single step.
- Published in:
- Nature Genetics, 2002, v. 30, n. 1, p. 31, doi. 10.1038/ng797
- By:
- Publication type:
- Article
Production of a mouse line with a conditional Crim1 mutant allele.
- Published in:
- Genesis: The Journal of Genetics & Development, 2012, v. 50, n. 9, p. 711, doi. 10.1002/dvg.22032
- By:
- Publication type:
- Article
Growth Arrest Specific 2 (GAS2) is a Critical Mediator of Germ Cell Cyst Breakdown and Folliculogenesis in Mice.
- Published in:
- Scientific Reports, 2016, p. 34956, doi. 10.1038/srep34956
- By:
- Publication type:
- Article
Production of Human Albumin in Pigs Through CRISPR/Cas9-Mediated Knockin of Human cDNA into Swine Albumin Locus in the Zygotes.
- Published in:
- Scientific Reports, 2015, p. 16705, doi. 10.1038/srep16705
- By:
- Publication type:
- Article
USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39412-6
- By:
- Publication type:
- Article
Ca<sup>2+</sup> permeation and/or binding to Ca<sub>V</sub>1.1 fine-tunes skeletal muscle Ca<sup>2+</sup> signaling to sustain muscle function.
- Published in:
- Skeletal Muscle, 2015, v. 5, n. 1, p. 1, doi. 10.1186/s13395-014-0027-1
- By:
- Publication type:
- Article
Ca<sup>2+</sup> permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca<sup>2+</sup> signaling to sustain muscle function.
- Published in:
- Skeletal Muscle, 2015, v. 5, n. 1, p. 53, doi. 10.1186/s13395-014-0027-1
- By:
- Publication type:
- Article
Targeting of GFP-Cre to the Mouse <i>Cyp11a1</i> Locus Both Drives Cre Recombinase Expression in Steroidogenic Cells and Permits Generation of <i>Cyp11a1</i> Knock Out Mice.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084541
- By:
- Publication type:
- Article
The Fat Mass and Obesity Associated Gene FTO Functions in the Brain to Regulate Postnatal Growth in Mice.
- Published in:
- PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0014005
- By:
- Publication type:
- Article
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.
- Published in:
- EMBO Journal, 2008, v. 27, n. 14, p. 1932, doi. 10.1038/emboj.2008.120
- By:
- Publication type:
- Article
Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR‐Mediated Base Editors.
- Published in:
- Advanced Science, 2022, v. 9, n. 30, p. 1, doi. 10.1002/advs.202200717
- By:
- Publication type:
- Article
RECQL5 plays an essential role in maintaining genome stability and viability of triple‐negative breast cancer cells.
- Published in:
- Cancer Medicine, 2019, v. 8, n. 10, p. 4743, doi. 10.1002/cam4.2349
- By:
- Publication type:
- Article
The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory.
- Published in:
- Nature Cell Biology, 2008, v. 10, n. 9, p. 1083, doi. 10.1038/ncb1768
- By:
- Publication type:
- Article
Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.
- Published in:
- Cell Research, 2013, v. 23, n. 5, p. 720, doi. 10.1038/cr.2013.46
- By:
- Publication type:
- Article
Hypomorphism of Fto and Rpgrip1l causes obesity in mice.
- Published in:
- Journal of Clinical Investigation, 2016, v. 126, n. 5, p. 1897, doi. 10.1172/JCI85526
- By:
- Publication type:
- Article
Highly efficient ssODN‐mediated homology‐directed repair of DSBs generated by CRISPR/Cas9 in human 3PN zygotes.
- Published in:
- Molecular Reproduction & Development, 2018, v. 85, n. 6, p. 461, doi. 10.1002/mrd.22983
- By:
- Publication type:
- Article
The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites.
- Published in:
- Nature Communications, 2017, v. 8, n. 6, p. 15751, doi. 10.1038/ncomms15751
- By:
- Publication type:
- Article
A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice.
- Published in:
- Nature Communications, 2016, v. 7, n. 1, p. 10201, doi. 10.1038/ncomms10201
- By:
- Publication type:
- Article
Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse.
- Published in:
- FASEB Journal, 2006, v. 20, n. 2, p. 329, doi. 10.1096/fj.05-4497fje
- By:
- Publication type:
- Article
The NEK1 interact or, C21ORF2, is required for efficient DNA damage repair.
- Published in:
- Acta Biochimica et Biophysica Sinica, 2015, v. 47, n. 10, p. 834, doi. 10.1093/abbs/gmv076
- By:
- Publication type:
- Article
Loss of spindle assembly checkpoint--mediated inhibition of Cdc20 promotes tumorigenesis in mice.
- Published in:
- Journal of Cell Biology, 2009, v. 185, n. 6, p. 983, doi. 10.1083/jcb.200904020
- By:
- Publication type:
- Article
Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis.
- Published in:
- Human Molecular Genetics, 2017, v. 26, n. 13, p. 2398, doi. 10.1093/hmg/ddx128
- By:
- Publication type:
- Article
Inhibitory Phosphorylation of Separase Is Essential for Genome Stability and Viability of Murine Embryonic Germ Cells.
- Published in:
- PLoS Biology, 2008, v. 6, n. 1, p. e15, doi. 10.1371/journal.pbio.0060015
- By:
- Publication type:
- Article
LGR4 attenuates MGP expression and suppresses EGFR activation-induced triple-negative breast cancer metastasis.
- Published in:
- American Journal of Cancer Research, 2024, v. 14, n. 7, p. 3419, doi. 10.62347/THII9650
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- Publication type:
- Article
Transcription-Replication Collisions and Chromosome Fragility.
- Published in:
- Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.804547
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- Publication type:
- Article
Erratum: The anaphase promoting complex impacts repair choice by protecting ubiquitin signalling at DNA damage sites.
- Published in:
- Nature Communications, 2017, v. 8, n. 11, p. 16156, doi. 10.1038/ncomms16156
- By:
- Publication type:
- Article
Efficient gene editing in adult mouse livers via adenoviral delivery of CRISPR/Cas9.
- Published in:
- FEBS Letters, 2014, v. 588, n. 21, p. 3954, doi. 10.1016/j.febslet.2014.09.008
- By:
- Publication type:
- Article
Quantitation of circulating GDF-11 and β2-MG in aged patients with age-related impairment in cognitive function.
- Published in:
- Clinical Science, 2017, v. 131, n. 15, p. 1895, doi. 10.1042/CS20171028
- By:
- Publication type:
- Article
BRIT1/MCPH1 Is Essential for Mitotic and Meiotic Recombination DNA Repair and Maintaining Genomic Stability in Mice.
- Published in:
- PLoS Genetics, 2010, v. 6, n. 1, p. 1, doi. 10.1371/journal.pgen.1000826
- By:
- Publication type:
- Article
Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads.
- Published in:
- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05330-y
- By:
- Publication type:
- Article
Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity.
- Published in:
- 2022
- By:
- Publication type:
- Letter
Cdh1 Deficiency Sensitizes TNBC Cells to PARP Inhibitors.
- Published in:
- Genes, 2022, v. 13, n. 5, p. 803, doi. 10.3390/genes13050803
- By:
- Publication type:
- Article
Ubiquitin‐specific protease 28 deubiquitinates TCF7L2 to govern the action of the Wnt signaling pathway in hepatic carcinoma.
- Published in:
- Cancer Science, 2022, v. 113, n. 10, p. 3463, doi. 10.1111/cas.15509
- By:
- Publication type:
- Article
Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-
- Published in:
- Nature, 1997, v. 387, n. 6629, p. 151, doi. 10.1038/387151a0
- By:
- Publication type:
- Article
Podocyte expression of the CDK-inhibitor p57 during development and disease.
- Published in:
- Kidney International, 2001, v. 60, n. 6, p. 2235, doi. 10.1046/j.1523-1755.2001.00057.x
- By:
- Publication type:
- Article