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Specific Targeting of Plant and Apicomplexa Parasite Tubulin through Differential Screening Using In Silico and Assay-Based Approaches.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 10, p. 3085, doi. 10.3390/ijms19103085
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- Article
Les criblages phénotypiques ou comment faire d'une pierre deux coups: Découvrir la cible et la molécule pharmacologique capable de la réguler.
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- Médecine Sciences, 2013, v. 29, n. 10, p. 897, doi. 10.1051/medsci/20132910018
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- Article
Sulphamoylated 2-Methoxyestradiol Analogues Induce Apoptosis in Adenocarcinoma Cell Lines.
- Published in:
- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0071935
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- Article
Preclinical Evaluation of a Novel Small Molecule Inhibitor of LIM Kinases (LIMK) CEL_Amide in Philadelphia-Chromosome Positive (BCR::ABL+) Acute Lymphoblastic Leukemia (ALL).
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- Journal of Clinical Medicine, 2022, v. 11, n. 22, p. 6761, doi. 10.3390/jcm11226761
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- Article
Sulfamoylated Estradiol Analogs Targeting the Actin and Microtubule Cytoskeletons Demonstrate Anti-Cancer Properties In Vitro and In Ovo.
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- Cancers, 2024, v. 16, n. 17, p. 2941, doi. 10.3390/cancers16172941
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- Article
Two Antagonistic Microtubule Targeting Drugs Act Synergistically to Kill Cancer Cells.
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- Cancers, 2020, v. 12, n. 8, p. 2196, doi. 10.3390/cancers12082196
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- Article
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors.
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- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-52141-5
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- Article
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights.
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- FASEB Journal, 2010, v. 24, n. 9, p. 3171, doi. 10.1096/fj.09-143743
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- Article
Structure-function analysis of the beta regulatory subunit of protein kinase CK2 by targeting embryonic stem cell.
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- Molecular & Cellular Biochemistry, 2011, v. 356, n. 1/2, p. 75, doi. 10.1007/s11010-011-0955-6
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- Article
Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations.
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- Cancer Chemotherapy & Pharmacology, 2015, v. 75, n. 2, p. 431, doi. 10.1007/s00280-014-2653-z
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- Publication type:
- Article
A novel inhibitor of the mitochondrial respiratory complex I with uncoupling properties exerts potent antitumor activity.
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- Cell Death & Disease, 2024, v. 15, n. 5, p. 1, doi. 10.1038/s41419-024-06668-9
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- Publication type:
- Article
Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.
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- 2013
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- Publication type:
- journal article
Azaindole derivatives are inhibitors of microtubule dynamics, with anti-cancer and anti-angiogenic activities.
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- British Journal of Pharmacology, 2013, v. 168, n. 3, p. 673, doi. 10.1111/j.1476-5381.2012.02230.x
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- Article
Characterization of Signalling Pathways That Link Apoptosis and Autophagy to Cell Death Induced by Estrone Analogues Which Reversibly Depolymerize Microtubules.
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- Molecules, 2021, v. 26, n. 3, p. 706, doi. 10.3390/molecules26030706
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- Publication type:
- Article
A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1.
- Published in:
- PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208979
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- Article