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Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability.
- Published in:
- Angewandte Chemie, 2016, v. 128, n. 44, p. 13904, doi. 10.1002/ange.201604207
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- Publication type:
- Article
Frontispiz: Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability.
- Published in:
- Angewandte Chemie, 2016, v. 128, n. 44, p. n/a, doi. 10.1002/ange.201684461
- By:
- Publication type:
- Article
The influence of intestinal lymphatic transport on the systemic exposure and brain deposition of a novel highly lipophilic compound with structural similarity to cholesterol.
- Published in:
- Journal of Pharmacy & Pharmacology, 2014, v. 66, n. 10, p. 1377, doi. 10.1111/jphp.12268
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- Publication type:
- Article
An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity.
- Published in:
- Journal of Pharmacy & Pharmacology, 2008, v. 60, n. 10, p. 1311, doi. 10.1211/jpp.60.10.0007
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- Publication type:
- Article
Examination of the impact of a range of Pluronic surfactants on the in-vitro solubilisation behaviour and oral bioavailability of lipidic formulations of atovaquone.
- Published in:
- Journal of Pharmacy & Pharmacology, 2006, v. 58, n. 6, p. 809
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- Publication type:
- Article
Evaluation of the impact of altered lipoprotein binding conditions on halofantrine induced QTc interval prolongation in an anaesthetized rabbit model.
- Published in:
- Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 1, p. 69
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- Publication type:
- Article
Effect of dietary fatty acids on the intestinal permeability of marker drug compounds in excised rat jejunum.
- Published in:
- Journal of Pharmacy & Pharmacology, 2002, v. 54, n. 6, p. 809, doi. 10.1211/0022357021779159
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- Publication type:
- Article
Evaluation of the in-vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products.
- Published in:
- Journal of Pharmacy & Pharmacology, 2002, v. 54, n. 1, p. 29, doi. 10.1211/0022357021771896
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- Publication type:
- Article
The impact of P-glycoprotein efflux on enterocyte residence time and enterocyte-based metabolism of verapamil.
- Published in:
- Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 12, p. 1611, doi. 10.1211/0022357011778214
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- Publication type:
- Article
From sewer to saviour - targeting the lymphatic system to promote drug exposure and activity.
- Published in:
- 2015
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- Publication type:
- journal article
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs.
- Published in:
- Nature Reviews Drug Discovery, 2007, v. 6, n. 3, p. 231, doi. 10.1038/nrd2197
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- Publication type:
- Article
Triglyceride-Mimetic Prodrugs of Buprenorphine Enhance Oral Bioavailability via Promotion of Lymphatic Transport.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.879660
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- Publication type:
- Article
Triglyceride-Mimetic Prodrugs of Buprenorphine Enhance Oral Bioavailability via Promotion of Lymphatic Transport.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.879660
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- Publication type:
- Article
Intestinal Lymph Flow, and Lipid and Drug Transport Scale Allometrically From Pre-clinical Species to Humans.
- Published in:
- Frontiers in Physiology, 2020, v. 11, p. 1, doi. 10.3389/fphys.2020.00458
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- Publication type:
- Article
Increased In Vivo Exposure of N-(4-Hydroxyphenyl) Retinamide (4-HPR) to Achieve Plasma Concentrations Effective against Dengue Virus.
- Published in:
- Pharmaceutics, 2023, v. 15, n. 7, p. 1974, doi. 10.3390/pharmaceutics15071974
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- Publication type:
- Article
Ionic Liquid Forms of the Antimalarial Lumefantrine in Combination with LFCS Type IIIB Lipid-Based Formulations Preferentially Increase Lipid Solubility, In Vitro Solubilization Behavior and In Vivo Exposure.
- Published in:
- Pharmaceutics, 2020, v. 12, n. 1, p. 17, doi. 10.3390/pharmaceutics12010017
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- Publication type:
- Article
Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability.
- Published in:
- Angewandte Chemie International Edition, 2016, v. 55, n. 44, p. 13700, doi. 10.1002/anie.201604207
- By:
- Publication type:
- Article
Frontispiece: Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability.
- Published in:
- Angewandte Chemie International Edition, 2016, v. 55, n. 44, p. n/a, doi. 10.1002/anie.201684461
- By:
- Publication type:
- Article
Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids.
- Published in:
- Pharmaceutical Research, 2022, v. 39, n. 10, p. 2405, doi. 10.1007/s11095-022-03305-y
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- Publication type:
- Article
Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide.
- Published in:
- Pharmaceutical Research, 2021, v. 38, n. 6, p. 1125, doi. 10.1007/s11095-021-03063-3
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- Publication type:
- Article
Quantifying In Vivo Luminal Drug Solubilization -Supersaturation-Precipitation Profiles to Explain the Performance of Lipid Based Formulations.
- Published in:
- Pharmaceutical Research, 2020, v. 37, n. 3, p. 1, doi. 10.1007/s11095-020-2762-9
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- Publication type:
- Article
Lipids in the Stomach – Implications for the Evaluation of Food Effects on Oral Drug Absorption.
- Published in:
- Pharmaceutical Research, 2018, v. 35, n. 3, p. N.PAG, doi. 10.1007/s11095-017-2289-x
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- Publication type:
- Article
Glass transition temperatures of poly(alkyl α-cyanoacrylates).
- Published in:
- Journal of Applied Polymer Science, 1973, v. 17, n. 11, p. 3509, doi. 10.1002/app.1973.070171122
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- Publication type:
- Article
A model for gel drying.
- Published in:
- Journal of Applied Polymer Science, 1973, v. 17, n. 2, p. 605, doi. 10.1002/app.1973.070170223
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- Publication type:
- Article
Wave energy asymmetry in shallow bays.
- Published in:
- Geophysical Research Letters, 2010, v. 37, n. 24, p. n/a, doi. 10.1029/2010GL045254
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- Publication type:
- Article
Does stereoselective lymphatic absorption contribute to the enantioselective pharmacokinetics of halofantrine In Vivo?
- Published in:
- Biopharmaceutics & Drug Disposition, 2003, v. 24, n. 4, p. 153, doi. 10.1002/bdd.351
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- Publication type:
- Article
Clinical and histopathological features of parvovirus B19 infection in the human fetus.
- Published in:
- BJOG: An International Journal of Obstetrics & Gynaecology, 1992, v. 99, n. 7, p. 566, doi. 10.1111/j.1471-0528.1992.tb13822.x
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- Publication type:
- Article
Criminal and Victim: Crime and Society in Early Nineteenth-Century England (Book).
- Published in:
- 1986
- By:
- Publication type:
- Book Review
Molecular modeling of lipid drug formulations.
- Published in:
- 2012
- By:
- Publication type:
- Abstract
Correlation of antenatal ultrasonography and pathological examinations in 153 malformed fetuses.
- Published in:
- 1993
- By:
- Publication type:
- journal article
Did British Capitalism Breed Inequality? (Book).
- Published in:
- 1986
- By:
- Publication type:
- Book Review
The effects of rumen-degradable protein level on fermentation of corn-based diets in continuous culture.
- Published in:
- Journal of Animal Science, 2006, v. 84, p. 405
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- Publication type:
- Article
Effect of T-2 toxin on growth of ruminal bacteria in batch culture.
- Published in:
- Journal of Animal Science, 2006, v. 84, p. 86
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- Publication type:
- Article
Fructooligosaccharide supplementation in the yearling horse: Effects on fecal pH, microbial content, and volatile fatty acid concentrations.
- Published in:
- Journal of Animal Science, 2005, v. 83, n. 7, p. 1549, doi. 10.2527/2005.8371549x
- By:
- Publication type:
- Article
Introducing operations research into management and policy practices of a non-governmental organization (NGO): a partnership between an Indian leprosy NGO and an international academic institution.
- Published in:
- 2004
- By:
- Publication type:
- journal article
Clozapine discrimination with a low training dose distinguishes atypical from typical antipsychotic drugs in rats.
- Published in:
- Psychopharmacology, 2000, v. 149, n. 2, p. 189, doi. 10.1007/s002139900366
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- Publication type:
- Article
The discriminative stimulus properties of the atypical antipsychotic olanzapine in rats.
- Published in:
- Psychopharmacology, 2000, v. 148, n. 3, p. 224, doi. 10.1007/s002130050046
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- Publication type:
- Article
Dietary docosahexaenoic acid supplementation enhances expression of fatty acid‐binding protein 5 at the blood–brain barrier and brain docosahexaenoic acid levels.
- Published in:
- Journal of Neurochemistry, 2018, v. 146, n. 2, p. 186, doi. 10.1111/jnc.14342
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- Publication type:
- Article
Reduced blood-brain barrier expression of fatty acid-binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega-3 fatty acid diets.
- Published in:
- Journal of Neurochemistry, 2018, v. 144, n. 1, p. 81, doi. 10.1111/jnc.14249
- By:
- Publication type:
- Article
Comparison of agar plate and real-time PCR on enumeration of Lactobacillus, Clostridium perfringens and total anaerobic bacteria in dog faeces.
- Published in:
- Letters in Applied Microbiology, 2006, v. 42, n. 5, p. 490, doi. 10.1111/j.1472-765X.2006.01893.x
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- Publication type:
- Article
Niche overlap and competition in an insular small mammal fauna: a test of the niche overlap hypothesis
- Published in:
- Oikos, 1982, v. 39, n. 2, p. 228, doi. 10.2307/3544489
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- Publication type:
- Article
Wage Determination by Selling Price Sliding Scales 1870-1914.
- Published in:
- Manchester School (1463-6786), 1971, v. 39, n. 1, p. 13, doi. 10.1111/j.1467-9957.1971.tb00364.x
- By:
- Publication type:
- Article
INDUSTRIAL PEACE IN THE COTTON TRADE 1875-1913.
- Published in:
- Bulletin of Economic Research, 1967, v. 19, n. 1, p. 49, doi. 10.1111/j.1467-8586.1967.tb00400.x
- By:
- Publication type:
- Article
Fatty Acid-Binding Protein 5 at the Blood–Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function.
- Published in:
- Journal of Neuroscience, 2016, v. 36, n. 46, p. 11755, doi. 10.1523/JNEUROSCI.1583-16.2016
- By:
- Publication type:
- Article
Transfusion medicine in India: a survey of current practice.
- Published in:
- Transfusion Medicine, 2003, v. 13, n. 1, p. 17, doi. 10.1046/j.1365-3148.2003.00417.x
- By:
- Publication type:
- Article
Intervention to promote appropriate blood use in India.
- Published in:
- Transfusion Medicine, 2002, v. 12, n. 6, p. 357, doi. 10.1046/j.1365-3148.2002.00404.x
- By:
- Publication type:
- Article
Structure preserving and energy dissipative contact approaches for implicit dynamics.
- Published in:
- International Journal for Numerical Methods in Engineering, 2024, v. 125, n. 10, p. 1, doi. 10.1002/nme.7454
- By:
- Publication type:
- Article
Adherence to tuberculosis treatment: lessons from the urban setting of Delhi, India.
- Published in:
- 2003
- By:
- Publication type:
- journal article
Tuberculosis treatment in complex emergencies: are risks outweighing benefits?
- Published in:
- 2003
- By:
- Publication type:
- journal article
TB control, poverty, and vulnerability in Delhi, India.
- Published in:
- 2002
- By:
- Publication type:
- journal article