Works by Polster, Tilman

Results: 34

Long‐term safety and effectiveness of fenfluramine in children and adults with Dravet syndrome.

Published in:

Epilepsia (Series 4), 2025, v. 66, n. 6, p. 1919, doi. 10.1111/epi.18342

By:

Scheffer, Ingrid E.;
Nabbout, Rima;
Lagae, Lieven;
Devinsky, Orrin;
Auvin, Stéphane;
Thiele, Elizabeth A.;
Wirrell, Elaine C.;
Polster, Tilman;
Specchio, Nicola;
Pringsheim, Milka;
Imai, Katsumi;
Lock, Michael D.;
Langlois, Mélanie;
Roper, Rebecca Zhang;
Lothe, Amélie;
Sullivan, Joseph

Publication type:

Article

Ethosuximide lowers lamotrigine serum concentrations: Evidence for a clinically relevant interaction.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 6, p. e73, doi. 10.1111/epi.17952

By:

Hagemann, Anne;
Herting, Arne;
Klimpel, Dennis;
Bien, Christian G.;
Polster, Tilman

Publication type:

Article

Critical incidents, nocturnal supervision, and caregiver knowledge on SUDEP in patients with Dravet syndrome: A prospective multicenter study in Germany.

Published in:

Epilepsia (Series 4), 2024, v. 65, n. 1, p. 115, doi. 10.1111/epi.17799

By:

Maltseva, Margarita;
Rosenow, Felix;
Schubert‐Bast, Susanne;
Flege, Silke;
Wolff, Markus;
von Spiczak, Sarah;
Trollmann, Regina;
Syrbe, Steffen;
Ruf, Susanne;
Polster, Tilman;
Neubauer, Bernd A.;
Mayer, Thomas;
Jacobs, Julia;
Kurlemann, Gerhard;
Kluger, Gerhard;
Klotz, Kerstin A.;
Kieslich, Matthias;
Kay, Lara;
Hornemann, Frauke;
Bettendorf, Ulrich

Publication type:

Article

Fenfluramine in the treatment of Dravet syndrome: Results of a third randomized, placebo‐controlled clinical trial.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 10, p. 2653, doi. 10.1111/epi.17737

By:

Sullivan, Joseph;
Lagae, Lieven;
Cross, J. Helen;
Devinsky, Orrin;
Guerrini, Renzo;
Knupp, Kelly G.;
Laux, Linda;
Nikanorova, Marina;
Polster, Tilman;
Talwar, Dinesh;
Ceulemans, Berten;
Nabbout, Rima;
Farfel, Gail M.;
Galer, Bradley S.;
Gammaitoni, Arnold R.;
Lock, Michael;
Agarwal, Anupam;
Scheffer, Ingrid E.;
Gill, Deepak;
Riney, Kate

Publication type:

Article

Hemispherotomy in children: A retrospective analysis of 152 surgeries at a single center and predictors for long‐term seizure outcome.

Published in:

Epilepsia (Series 4), 2023, v. 64, n. 7, p. 1800, doi. 10.1111/epi.17632

By:

Kalbhenn, Thilo;
Cloppenborg, Thomas;
Woermann, Friedrich G.;
Hagemann, Anne;
Polster, Tilman;
Coras, Roland;
Blümcke, Ingmar;
Bien, Christian G.;
Simon, Matthias

Publication type:

Article

Adjunctive everolimus therapy for tuberous sclerosis complex‐associated refractory seizures: Results from the postextension phase of EXIST‐3.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 12, p. 3029, doi. 10.1111/epi.17099

By:

Franz, David N.;
Lawson, John A.;
Yapici, Zuhal;
Ikeda, Hiroko;
Polster, Tilman;
Nabbout, Rima;
Curatolo, Paolo;
de Vries, Petrus J.;
Dlugos, Dennis J.;
Herbst, Fabian;
Peyrard, Severine;
Pelov, Diana;
French, Jacqueline A.

Publication type:

Article

Efficacy, tolerability, and retention of fenfluramine for the treatment of seizures in patients with Dravet syndrome: Compassionate use program in Germany.

Published in:

Epilepsia (Series 4), 2021, v. 62, n. 10, p. 2518, doi. 10.1111/epi.17034

By:

Strzelczyk, Adam;
Pringsheim, Milka;
Mayer, Thomas;
Polster, Tilman;
Klotz, Kerstin A.;
Muhle, Hiltrud;
Alber, Michael;
Trollmann, Regina;
Spors, Hartwig;
Kluger, Gerhard;
Kurlemann, Gerhard;
Schubert‐Bast, Susanne

Publication type:

Article

Fenfluramine HCl (Fintepla<sup>®</sup>) provides long‐term clinically meaningful reduction in seizure frequency: Analysis of an ongoing open‐label extension study.

Published in:

Epilepsia (Series 4), 2020, v. 61, n. 11, p. 2396, doi. 10.1111/epi.16722

By:

Sullivan, Joseph;
Scheffer, Ingrid E.;
Lagae, Lieven;
Nabbout, Rima;
Pringsheim, Milka;
Talwar, Dinesh;
Polster, Tilman;
Galer, Bradley;
Lock, Michael;
Agarwal, Anupam;
Gammaitoni, Arnold;
Morrison, Glenn;
Farfel, Gail

Publication type:

Article

Neonatal developmental and epileptic encephalopathy due to autosomal recessive variants in SLC13A5 gene.

Published in:

Epilepsia (Series 4), 2020, v. 61, n. 11, p. 2474, doi. 10.1111/epi.16699

By:

Matricardi, Sara;
De Liso, Paola;
Freri, Elena;
Costa, Paola;
Castellotti, Barbara;
Magri, Stefania;
Gellera, Cinzia;
Granata, Tiziana;
Musante, Luciana;
Lesca, Gaetan;
Oertel, Julie;
Craiu, Dana;
Hammer, Trine B.;
Møller, Rikke S.;
Barisic, Nina;
Abou Jamra, Rami;
Polster, Tilman;
Vigevano, Federico;
Marini, Carla

Publication type:

Article

Operative posterior disconnection in epilepsy surgery: Experience with 29 patients.

Published in:

Epilepsia (Series 4), 2019, v. 60, n. 9, p. 1973, doi. 10.1111/epi.16318

By:

Kalbhenn, Thilo;
Cloppenborg, Thomas;
Wörmann, Friedrich G.;
Blümcke, Ingmar;
Coras, Roland;
May, Theodor W.;
Polster, Tilman;
Simon, Matthias;
Bien, Christian G.

Publication type:

Article

A multicenter, matched case‐control analysis comparing burden‐of‐illness in Dravet syndrome to refractory epilepsy and seizure remission in patients and caregivers in Germany.

Published in:

Epilepsia (Series 4), 2019, v. 60, n. 8, p. 1697, doi. 10.1111/epi.16099

By:

Strzelczyk, Adam;
Schubert‐Bast, Susanne;
Bast, Thomas;
Bettendorf, Ulrich;
Fiedler, Barbara;
Hamer, Hajo M.;
Herting, Arne;
Kalski, Malin;
Kay, Lara;
Kieslich, Matthias;
Klein, Karl Martin;
Kluger, Gerhard;
Kurlemann, Gerhard;
Mayer, Thomas;
Neubauer, Bernd A.;
Polster, Tilman;
von Spiczak, Sarah;
Stephani, Ulrich;
Trollmann, Regina;
Wiemer‐Kruel, Adelheid

Publication type:

Article

Differences in pediatric and adult epilepsy surgery: A comparison at one center from 1990 to 2014.

Published in:

Epilepsia (Series 4), 2019, v. 60, n. 2, p. 233, doi. 10.1111/epi.14627

By:

Cloppenborg, Thomas;
May, Theodor W.;
Blümcke, Ingmar;
Fauser, Susanne;
Grewe, Philip;
Hopf, Johanna L.;
Kalbhenn, Thilo;
Polster, Tilman;
Schulz, Reinhard;
Woermann, Friedrich G.;
Bien, Christian G.

Publication type:

Article

Revised version of quality guidelines for presurgical epilepsy evaluation and surgical epilepsy therapy issued by the Austrian, German, and Swiss working group on presurgical epilepsy diagnosis and operative epilepsy treatment.

Published in:

Epilepsia (Series 4), 2016, v. 57, n. 8, p. 1215, doi. 10.1111/epi.13449

By:

Rosenow, Felix;
Bast, Thomas;
Czech, Thomas;
Feucht, Martha;
Hans, Volkmar H.;
Helmstaedter, Christoph;
Huppertz, Hans‐Jürgen;
Noachtar, Soheyl;
Oltmanns, Frank;
Polster, Tilman;
Seeck, Margitta;
Trinka, Eugen;
Wagner, Kathrin;
Strzelczyk, Adam

Publication type:

Article

Diagnostic methods and treatment options for focal cortical dysplasia.

Published in:

Epilepsia (Series 4), 2015, v. 56, n. 11, p. 1669, doi. 10.1111/epi.13200

By:

Guerrini, Renzo;
Duchowny, Michael;
Jayakar, Prasanna;
Krsek, Pavel;
Kahane, Philippe;
Tassi, Laura;
Melani, Federico;
Polster, Tilman;
Andre, Véronique M.;
Cepeda, Carlos;
Krueger, Darcy A.;
Cross, J. Helen;
Spreafico, Roberto;
Cosottini, Mirco;
Gotman, Jean;
Chassoux, Francine;
Ryvlin, Philippe;
Bartolomei, Fabrice;
Bernasconi, Andrea;
Stefan, Hermann

Publication type:

Article

Detection of generalized tonic-clonic seizures by a wireless wrist accelerometer: A prospective, multicenter study.

Published in:

Epilepsia (Series 4), 2013, v. 54, n. 4, p. e58, doi. 10.1111/epi.12120

By:

Beniczky, Sándor;
Polster, Tilman;
Kjaer, Troels W.;
Hjalgrim, Helle

Publication type:

Article

Sleep quality, anxiety, symptoms of depression, and caregiver burden among those caring for patients with Dravet syndrome: a prospective multicenter study in Germany.

Published in:

Orphanet Journal of Rare Diseases, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13023-023-02697-3

By:

Maltseva, Margarita;
Schubert-Bast, Susanne;
Zöllner, Johann Philipp;
Bast, Thomas;
Mayer, Thomas;
von Spiczak, Sarah;
Ruf, Susanne;
Trollmann, Regina;
Wolff, Markus;
Hornemann, Frauke;
Klotz, Kerstin A.;
Jacobs, Julia;
Kurlemann, Gerhard;
Neubauer, Bernd A.;
Polster, Tilman;
Syrbe, Steffen;
Bertsche, Astrid;
Bettendorf, Ulrich;
Kluger, Gerhard;
Flege, Silke

Publication type:

Article

Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Frontal Lobe Epilepsy: A New Clinico-Pathological Entity.

Published in:

Brain Pathology, 2017, v. 27, n. 1, p. 26, doi. 10.1111/bpa.12347

By:

Schurr, Johannes;
Coras, Roland;
Rössler, Karl;
Pieper, Tom;
Kudernatsch, Manfred;
Holthausen, Hans;
Winkler, Peter;
Woermann, Friedrich;
Bien, Christian G.;
Polster, Tilman;
Schulz, Reinhard;
Kalbhenn, Thilo;
Urbach, Horst;
Becker, Albert;
Grunwald, Thomas;
Huppertz, Hans‐Juergen;
Gil‐Nagel, Antonio;
Toledano, Rafael;
Feucht, Martha;
Mühlebner, Angelika

Publication type:

Article

Specific pattern of maturation and differentiation in the formation of cortical tubers in tuberous sclerosis omplex (TSC): evidence from layer-specific marker expression.

Published in:

Journal of Neurodevelopmental Disorders, 2016, v. 8, n. 1, p. 1, doi. 10.1186/s11689-016-9142-0

By:

Mühlebner, Angelika;
Iyer, Anand;
van Scheppingen, Jackelien;
Anink, Jasper;
Jansen, Floor;
Veersema, Tim;
Braun, Kees;
Spliet, Wim;
van Hecke, Wim;
Söylemezoğlu, Figen;
Feucht, Martha;
Krsek, Pavel;
Zamecnik, Josef;
Bien, Christian;
Polster, Tilman;
Coras, Roland;
Blümcke, Ingmar;
Aronica, Eleonora

Publication type:

Article

Mutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly-capillary malformation syndrome.

Published in:

Nature Genetics, 2013, v. 45, n. 5, p. 556, doi. 10.1038/ng.2602

By:

McDonell, Laura M;
Mirzaa, Ghayda M;
Alcantara, Diana;
Schwartzentruber, Jeremy;
Carter, Melissa T;
Lee, Leo J;
Clericuzio, Carol L;
Graham, John M;
Morris-Rosendahl, Deborah J;
Polster, Tilman;
Acsadi, Gyula;
Townshend, Sharron;
Williams, Simon;
Halbert, Anne;
Isidor, Bertrand;
David, Albert;
Smyser, Christopher D;
Paciorkowski, Alex R;
Willing, Marcia;
Woulfe, John

Publication type:

Article

Infantile spinal muscular atrophy with respiratory distress type 1 (SMARD1).

Published in:

Annals of Neurology, 2003, v. 54, n. 6, p. 719

By:

Katja Grohmann;
Raymonda Varon;
Piroschka Stolz;
Markus Schuelke;
Catrin Janetzki;
Enrico Bertini;
Kate Bushby;
Francesco Muntoni;
Robert Ouvrier;
Lionel Van Maldergem;
Nathalie M. L. A. Goemans;
Hanns Lochmüller;
Stephan Eichholz;
Coleen Adams;
Friedrich Bosch;
Padraic Grattan-Smith;
Carmen Navarro;
Heidemarie Neitzel;
Tilman Polster;
Haluk Topaloğlu

Publication type:

Article

Lack of creatine in muscle and brain in an adult with GAMT deficiency.

Published in:

Annals of Neurology, 2003, v. 53, n. 2, p. 248

By:

Andreas Schulze;
Peter Bachert;
Heinz Schlemmer;
Inga Harting;
Tilman Polster;
Gajja S. Salomons;
Nanda M. Verhoeven;
Cornelis Jakobs;
Brian Fowler;
Georg F. Hoffmann;
Ertan Mayatepek

Publication type:

Article

The P429L loss of function mutation of the human glycine transporter 2 associated with hyperekplexia.

Published in:

European Journal of Neuroscience, 2019, v. 50, n. 12, p. 3906, doi. 10.1111/ejn.14533

By:

Kitzenmaier, Alexandra;
Schaefer, Natascha;
Kasaragod, Vikram Babu;
Polster, Tilman;
Hantschmann, Ralph;
Schindelin, Hermann;
Villmann, Carmen

Publication type:

Article

DNA methylation-based classification of malformations of cortical development in the human brain.

Published in:

Acta Neuropathologica, 2022, v. 143, n. 1, p. 93, doi. 10.1007/s00401-021-02386-0

By:

Jabari, Samir;
Kobow, Katja;
Pieper, Tom;
Hartlieb, Till;
Kudernatsch, Manfred;
Polster, Tilman;
Bien, Christian G.;
Kalbhenn, Thilo;
Simon, Matthias;
Hamer, Hajo;
Rössler, Karl;
Feucht, Martha;
Mühlebner, Angelika;
Najm, Imad;
Peixoto-Santos, José Eduardo;
Gil-Nagel, Antonio;
Delgado, Rafael Toledano;
Aledo-Serrano, Angel;
Hou, Yanghao;
Coras, Roland

Publication type:

Article

Mosaic trisomy of chromosome 1q in human brain tissue associates with unilateral polymicrogyria, very early-onset focal epilepsy, and severe developmental delay.

Published in:

Acta Neuropathologica, 2020, v. 140, n. 6, p. 881, doi. 10.1007/s00401-020-02228-5

By:

Kobow, Katja;
Jabari, Samir;
Pieper, Tom;
Kudernatsch, Manfred;
Polster, Tilman;
Woermann, Friedrich G.;
Kalbhenn, Thilo;
Hamer, Hajo;
Rössler, Karl;
Mühlebner, Angelika;
Spliet, Wim G. M.;
Feucht, Martha;
Hou, Yanghao;
Stichel, Damian;
Korshunov, Andrey;
Sahm, Felix;
Coras, Roland;
Blümcke, Ingmar;
von Deimling, Andreas

Publication type:

Article

Heterozygous loss-of-function variants in DOCK4 cause neurodevelopmental delay and microcephaly.

Published in:

Human Genetics, 2024, v. 143, n. 3, p. 455, doi. 10.1007/s00439-024-02655-4

By:

Herbst, Charlotte;
Bothe, Viktoria;
Wegler, Meret;
Axer-Schaefer, Susanne;
Audebert-Bellanger, Séverine;
Gecz, Jozef;
Cogne, Benjamin;
Feldman, Hagit Baris;
Horn, Anselm H. C.;
Hurst, Anna C. E.;
Kelly, Melissa A.;
Kruer, Michael C.;
Kurolap, Alina;
Laquerriere, Annie;
Li, Megan;
Mark, Paul R.;
Morawski, Markus;
Nizon, Mathilde;
Pastinen, Tomi;
Polster, Tilman

Publication type:

Article

An examination of the efficacy and safety of fenfluramine in adults, children, and adolescents with Dravet syndrome in a real‐world practice setting: A report from the Fenfluramine European Early Access Program.

Published in:

Epilepsia Open, 2022, v. 7, n. 4, p. 578, doi. 10.1002/epi4.12624

By:

Guerrini, Renzo;
Specchio, Nicola;
Aledo‐Serrano, Ángel;
Pringsheim, Milka;
Darra, Francesca;
Mayer, Thomas;
Gil‐Nagel, Antonio;
Polster, Tilman;
Zuberi, Sameer M.;
Lothe, Amélie;
Gammaitoni, Arnold;
Strzelczyk, Adam

Publication type:

Article

Genetic generalized epilepsies with frontal lesions mimicking migratory disorders on the epilepsy monitoring unit.

Published in:

Epilepsia Open, 2020, v. 5, n. 2, p. 176, doi. 10.1002/epi4.12385

By:

Fauser, Susanne;
Cloppenborg, Thomas;
Polster, Tilman;
Specht, Ulrich;
Woermann, Friedrich G.;
Bien, Christian G.

Publication type:

Article

Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course.

Published in:

2019

By:

Esposito, Alessandro;
Falace, Antonio;
Wagner, Matias;
Gal, Moran;
Mei, Davide;
Conti, Valerio;
Pisano, Tiziana;
Aprile, Davide;
Cerullo, Maria Sabina;
Fusco, Antonio De;
Giovedì, Silvia;
Seibt, Annette;
Magen, Daniella;
Polster, Tilman;
Eran, Ayelet;
Stenton, Sarah L;
Fiorillo, Chiara;
Ravid, Sarit;
Mayatepek, Ertan;
Hafner, Hava

Publication type:

journal article

Delineating SPTAN1 associated phenotypes: from isolated epilepsy to encephalopathy with progressive brain atrophy.

Published in:

2017

By:

Syrbe, Steffen;
Harms, Frederike L.;
Parrini, Elena;
Montomoli, Martino;
Mütze, Ulrike;
Helbig, Katherine L.;
Polster, Tilman;
Albrecht, Beate;
Bernbeck, Ulrich;
van Binsbergen, Ellen;
Biskup, Saskia;
Burglen, Lydie;
Denecke, Jonas;
Heron, Bénédicte;
Heyne, Henrike O.;
Hoffmann, Georg F.;
Hornemann, Frauke;
Takeshi Matsushige;
Ryuki Matsuura;
Mitsuhiro Kato

Publication type:

journal article

CAD mutations and uridine-responsive epileptic encephalopathy.

Published in:

2017

By:

Koch, Johannes;
Mayr, Johannes A.;
Alhaddad, Bader;
Rauscher, Christian;
Bierau, Jörgen;
Kovacs-Nagy, Reka;
Coene, Karlien L. M.;
Bader, Ingrid;
Holzhacker, Monika;
Prokisch, Holger;
Venselaar, Hanka;
Wevers, Ron A.;
Distelmaier, Felix;
Polster, Tilman;
Leiz, Steffen;
Betzler, Cornelia;
Strom, Tim M.;
Sperl, Wolfgang;
Meitinger, Thomas;
Wortmann, Saskia B.

Publication type:

journal article

Intelligence quotient improves after antiepileptic drug withdrawal following pediatric epilepsy surgery.

Published in:

Annals of Neurology, 2015, v. 78, n. 1, p. 104, doi. 10.1002/ana.24427

By:

Boshuisen, Kim;
van Schooneveld, Monique M. J.;
Uiterwaal, Cuno S. P. M.;
Cross, J. Helen;
Harrison, Sue;
Polster, Tilman;
Daehn, Marion;
Djimjadi, Sarina;
Yalnizoglu, Dilek;
Turanli, Guzide;
Sassen, Robert;
Hoppe, Christian;
Kuczaty, Stefan;
Barba, Carmen;
Kahane, Philippe;
Schubert‐Bast, Susanne;
Reuner, Gitta;
Bast, Thomas;
Strobl, Karl;
Mayer, Hans

Publication type:

Article

Biallelic mutations in PIGP cause developmental and epileptic encephalopathy.

Published in:

Annals of Clinical & Translational Neurology, 2019, v. 6, n. 5, p. 968, doi. 10.1002/acn3.768

By:

Krenn, Martin;
Knaus, Alexej;
Westphal, Dominik S.;
Wortmann, Saskia B.;
Polster, Tilman;
Woermann, Friedrich G.;
Karenfort, Michael;
Mayatepek, Ertan;
Meitinger, Thomas;
Wagner, Matias;
Distelmaier, Felix

Publication type:

Article

Exploring the relationships between composite scores of disease severity, seizure-freedom and quality of life in Dravet syndrome.

Published in:

Neurological Research & Practice, 2022, v. 4, n. 1, p. 1, doi. 10.1186/s42466-022-00186-9

By:

Strzelczyk, Adam;
Kurlemann, Gerhard;
Bast, Thomas;
Bettendorf, Ulrich;
Kluger, Gerhard;
Mayer, Thomas;
Neubauer, Bernd A.;
Polster, Tilman;
von Spiczak, Sarah;
Trollmann, Regina;
Wolff, Markus;
Toward, Toby;
Gruenert, Jens;
Gibson, Eddie;
Pritchard, Clive;
Carroll, Joe;
Rosenow, Felix;
Schubert-Bast, Susanne

Publication type:

Article

Exploring the relationships between composite scores of disease severity, seizure-freedom and quality of life in Dravet syndrome.

Published in:

Neurological Research & Practice, 2022, v. 4, n. 1, p. 1, doi. 10.1186/s42466-022-00186-9

By:

Strzelczyk, Adam;
Kurlemann, Gerhard;
Bast, Thomas;
Bettendorf, Ulrich;
Kluger, Gerhard;
Mayer, Thomas;
Neubauer, Bernd A.;
Polster, Tilman;
von Spiczak, Sarah;
Trollmann, Regina;
Wolff, Markus;
Toward, Toby;
Gruenert, Jens;
Gibson, Eddie;
Pritchard, Clive;
Carroll, Joe;
Rosenow, Felix;
Schubert-Bast, Susanne

Publication type:

Article