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Towards a new combination therapy for tuberculosis with next generation benzothiazinones.
Published in:
EMBO Molecular Medicine, 2014, v. 6, n. 3, p. 372, doi. 10.1002/emmm.201303575
By:
- Makarov, Vadim;
- Lechartier, Benoit;
- Zhang, Ming;
- Neres, João;
- Sar, Astrid M;
- Raadsen, Susanne A;
- Hartkoorn, Ruben C;
- Ryabova, Olga B;
- Vocat, Anthony;
- Decosterd, Laurent A;
- Widmer, Nicolas;
- Buclin, Thierry;
- Bitter, Wilbert;
- Andries, Koen;
- Pojer, Florence;
- Dyson, Paul J;
- Cole, Stewart T
Publication type:
Article
Towards a new tuberculosis drug: pyridomycin - nature's isoniazid.
Published in:
EMBO Molecular Medicine, 2012, v. 4, n. 10, p. 1032, doi. 10.1002/emmm.201201689
By:
- Hartkoorn, Ruben C.;
- Sala, Claudia;
- Neres, João;
- Pojer, Florence;
- Magnet, Sophie;
- Mukherjee, Raju;
- Uplekar, Swapna;
- Boy-Röttger, Stefanie;
- Altmann, Karl-Heinz;
- Cole, Stewart T.
Publication type:
Article
Peptide Ligands Stabilized by Small Molecules.
Published in:
Angewandte Chemie International Edition, 2014, v. 53, n. 6, p. 1602, doi. 10.1002/anie.201309459
By:
- Chen, Shiyu;
- Bertoldo, Davide;
- Angelini, Alessandro;
- Pojer, Florence;
- Heinis, Christian
Publication type:
Article
The cysteine desulfurase IscS of Mycobacterium tuberculosis is involved in iron-sulfur cluster biogenesis and oxidative stress defence.
Published in:
Biochemical Journal, 2014, v. 459, n. 3, p. 467, doi. 10.1042/BJ20130732
By:
- RYBNIKER, Jan;
- POJER, Florence;
- MARIENHAGEN, Jan;
- KOLLY, Gaëlle S.;
- CHEN, Jeffrey M.;
- GUMPEL, Edeltraud VAN;
- HARTMANN, Pia;
- COLE, Stewart T.
Publication type:
Article
A Nanoscaffolded Spike-RBD Vaccine Provides Protection against SARS-CoV-2 with Minimal Anti-Scaffold Response.
Published in:
Vaccines, 2021, v. 9, n. 5, p. 431, doi. 10.3390/vaccines9050431
By:
- Lainšček, Duško;
- Fink, Tina;
- Forstnerič, Vida;
- Hafner-Bratkovič, Iva;
- Orehek, Sara;
- Strmšek, Žiga;
- Manček-Keber, Mateja;
- Pečan, Peter;
- Esih, Hana;
- Malenšek, Špela;
- Aupič, Jana;
- Dekleva, Petra;
- Plaper, Tjaša;
- Vidmar, Sara;
- Kadunc, Lucija;
- Benčina, Mojca;
- Omersa, Neža;
- Anderluh, Gregor;
- Pojer, Florence;
- Lau, Kelvin
Publication type:
Article
Author Correction: Internalization and vacuolar targeting of the brassinosteroid hormone receptor BRI1 are regulated by ubiquitination.
Published in:
2021
By:
- Martins, Sara;
- Dohmann, Esther M. N.;
- Cayrel, Anne;
- Johnson, Alexander;
- Fischer, Wolfgang;
- Pojer, Florence;
- Satiat-Jeunemaître, Béatrice;
- Jaillais, Yvon;
- Chory, Joanne;
- Geldner, Niko;
- Vert, Grégory
Publication type:
Correction Notice
Peptide Ligands Stabilized by Small Molecules.
Published in:
Angewandte Chemie, 2014, v. 126, n. 6, p. 1628, doi. 10.1002/ange.201309459
By:
- Chen, Shiyu;
- Bertoldo, Davide;
- Angelini, Alessandro;
- Pojer, Florence;
- Heinis, Christian
Publication type:
Article
Atypical DNA recognition mechanism used by the EspR virulence regulator of Mycobacterium tuberculosis.
Published in:
Molecular Microbiology, 2011, v. 82, n. 1, p. 251, doi. 10.1111/j.1365-2958.2011.07813.x
By:
- Blasco, Benjamin;
- Stenta, Marco;
- Alonso-Sarduy, Livan;
- Dietler, Giovanni;
- Peraro, Matteo Dal;
- Cole, Stewart T.;
- Pojer, Florence
Publication type:
Article
High-affinity peptides developed against calprotectin and their application as synthetic ligands in diagnostic assays.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38075-7
By:
- Díaz-Perlas, Cristina;
- Ricken, Benjamin;
- Farrera-Soler, Lluc;
- Guschin, Dmitrii;
- Pojer, Florence;
- Lau, Kelvin;
- Gerhold, Christian-Benedikt;
- Heinis, Christian
Publication type:
Article
The Crystal Structures of Apo and cAMP-Bound GlxR from Corynebacterium glutamicum Reveal Structural and Dynamic Changes upon cAMP Binding in CRP/FNR Family Transcription Factors.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0113265
By:
- Townsend, Philip D.;
- Jungwirth, Britta;
- Pojer, Florence;
- Bußmann, Michael;
- Money, Victoria A.;
- Cole, Stewart T.;
- Pühler, Alfred;
- Tauch, Andreas;
- Bott, Michael;
- Cann, Martin J.;
- Pohl, Ehmke
Publication type:
Article
Characterization of Molecular Determinants of the Conformational Stability of Macrophage Migration Inhibitory Factor: Leucine 46 Hydrophobic Pocket.
Published in:
PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045024
By:
- El-Turk, Farah;
- Fauvet, Bruno;
- Ashrafi, Amer;
- Ouertatani-Sakouhi, Hajer;
- Min-Kyu Cho;
- Neri, Marilisa;
- Cascella, Michele;
- Rothlisberger, Ursula;
- Pojer, Florence;
- Zweckstetter, Markus;
- Lashuel, Hilal;
- Vertessy, Beata G.
Publication type:
Article
Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence.
Published in:
Molecular Microbiology, 2013, v. 89, n. 6, p. 1154, doi. 10.1111/mmi.12336
By:
- Chen, Jeffrey M.;
- Zhang, Ming;
- Rybniker, Jan;
- Boy‐Röttger, Stefanie;
- Dhar, Neeraj;
- Pojer, Florence;
- Cole, Stewart T.
Publication type:
Article
Manganese Transfer Hydrogenases Based on the Biotin‐Streptavidin Technology.
Published in:
Angewandte Chemie, 2023, v. 135, n. 43, p. 1, doi. 10.1002/ange.202311896
By:
- Wang, Weijin;
- Tachibana, Ryo;
- Zou, Zhi;
- Chen, Dongping;
- Zhang, Xiang;
- Lau, Kelvin;
- Pojer, Florence;
- Ward, Thomas R.;
- Hu, Xile
Publication type:
Article
A rheostat mechanism governs the bifurcation of carbon flux in mycobacteria.
Published in:
Nature Communications, 2016, v. 7, n. 8, p. 12527, doi. 10.1038/ncomms12527
By:
- Murima, Paul;
- Zimmermann, Michael;
- Chopra, Tarun;
- Pojer, Florence;
- Fonti, Giulia;
- Dal Peraro, Matteo;
- Alonso, Sylvie;
- Sauer, Uwe;
- Pethe, Kevin;
- McKinney, John D.
Publication type:
Article
Lansoprazole is an antituberculous prodrug targeting cytochrome bc<sub>1</sub>.
Published in:
Nature Communications, 2015, v. 6, n. 7, p. 7659, doi. 10.1038/ncomms8659
By:
- Rybniker, Jan;
- Vocat, Anthony;
- Sala, Claudia;
- Busso, Philippe;
- Pojer, Florence;
- Benjak, Andrej;
- Cole, Stewart T.
Publication type:
Article
Internalization and vacuolar targeting of the brassinosteroid hormone receptor BRI1 are regulated by ubiquitination.
Published in:
Nature Communications, 2015, v. 6, n. 1, p. 1, doi. 10.1038/ncomms7151
By:
- Martins, Sara;
- Dohmann, Esther M. N.;
- Cayrel, Anne;
- Johnson, Alexander;
- Fischer, Wolfgang;
- Pojer, Florence;
- Satiat-Jeunemaître, Béatrice;
- Jaillais, Yvon;
- Chory, Joanne;
- Geldner, Niko;
- Vert, Grégory
Publication type:
Article
Internalization and vacuolar targeting of the brassinosteroid hormone receptor BRI1 are regulated by ubiquitination.
Published in:
Nature Communications, 2015, v. 6, n. 1, p. 6151, doi. 10.1038/ncomms7151
By:
- Martins, Sara;
- Dohmann, Esther M. N.;
- Cayrel, Anne;
- Johnson, Alexander;
- Fischer, Wolfgang;
- Pojer, Florence;
- Satiat-Jeunemaître, Béatrice;
- Jaillais, Yvon;
- Chory, Joanne;
- Geldner, Niko;
- Vert, Grégory
Publication type:
Article
Manganese Transfer Hydrogenases Based on the Biotin‐Streptavidin Technology.
Published in:
Angewandte Chemie International Edition, 2023, v. 62, n. 43, p. 1, doi. 10.1002/anie.202311896
By:
- Wang, Weijin;
- Tachibana, Ryo;
- Zou, Zhi;
- Chen, Dongping;
- Zhang, Xiang;
- Lau, Kelvin;
- Pojer, Florence;
- Ward, Thomas R.;
- Hu, Xile
Publication type:
Article
Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein.
Published in:
PLoS Pathogens, 2012, v. 8, n. 3, p. 1, doi. 10.1371/journal.ppat.1002621
By:
- Blasco, Benjamin;
- Chen, Jeffrey M.;
- Hartkoorn, Ruben;
- Sala, Claudia;
- Uplekar, Swapna;
- Rougemont, Jacques;
- Pojer, Florence;
- Cole, Stewart T.
Publication type:
Article
Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis.
Published in:
Science Translational Medicine, 2012, v. 4, n. 150, p. 1, doi. 10.1126/scitranslmed.3004395
By:
- Neres, João;
- Pojer, Florence;
- Molteni, Elisabetta;
- Chiarelli, Laurent R.;
- Dhar, Neeraj;
- Boy-Röttger, Stefanie;
- Buroni, Silvia;
- Fullam, Elizabeth;
- Degiacomi, Giulia;
- Lucarelli, Anna Paola;
- Read, Randy J.;
- Zanoni, Giuseppe;
- Edmondson, Dale E.;
- De Rossi, Edda;
- Pasca, Maria Rosalia;
- McKinney, John D.;
- Dyson, Paul J.;
- Riccardi, Giovanna;
- Mattevi, Andrea;
- Cole, Stewart T.
Publication type:
Article
Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Published in:
Nature, 2012, v. 485, n. 7399, p. 530, doi. 10.1038/nature11009
By:
- Ngaki, Micheline N.;
- Louie, Gordon V.;
- Philippe, Ryan N.;
- Manning, Gerard;
- Pojer, Florence;
- Bowman, Marianne E.;
- Li, Ling;
- Larsen, Elise;
- Wurtele, Eve Syrkin;
- Noel, Joseph P.
Publication type:
Article
Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02313-6
By:
- Reckel, Sina;
- Gehin, Charlotte;
- Tardivon, Delphine;
- Georgeon, Sandrine;
- Kükenshöner, Tim;
- Löhr, Frank;
- Koide, Akiko;
- Buchner, Lena;
- Panjkovich, Alejandro;
- Reynaud, Aline;
- Pinho, Sara;
- Gerig, Barbara;
- Svergun, Dmitri;
- Pojer, Florence;
- Güntert, Peter;
- Dötsch, Volker;
- Koide, Shohei;
- Gavin, Anne-Claude;
- Hantschel, Oliver
Publication type:
Article
Standardized Production of Anti‐Desmoglein 3 Antibody AK23 for Translational Pemphigus Vulgaris Research.
Published in:
Current Protocols, 2024, v. 4, n. 8, p. 1, doi. 10.1002/cpz1.1118
By:
- Mueller, Eliane J.;
- Rahimi, Siavash;
- Sauta, Patrizia;
- Shojaeian, Taravat;
- Durrer, Laurence;
- Quinche, Soraya;
- Francois, Michael;
- Locher, Elisabeth;
- Edler, Monika;
- Illi, Marlies;
- Gentinetta, Thomas;
- Lau, Kelvin;
- Pojer, Florence;
- Borradori, Luca;
- Hariton, William V. J.
Publication type:
Article
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma.
Published in:
Science Translational Medicine, 2021, v. 13, n. 605, p. 1, doi. 10.1126/scitranslmed.abi8452
By:
- Fenwick, Craig;
- Turelli, Priscilla;
- Pellaton, Céline;
- Farina, Alex;
- Campos, Jérémy;
- Raclot, Charlène;
- Pojer, Florence;
- Cagno, Valeria;
- Nusslé, Semira Gonseth;
- D'Acremont, Valerie;
- Fehr, Jan;
- Puhan, Milo;
- Pantaleo, Giuseppe;
- Trono, Didier
Publication type:
Article
Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides.
Published in:
Nature Chemistry, 2014, v. 6, n. 11, p. 1009, doi. 10.1038/nchem.2043
By:
- Chen, Shiyu;
- Gopalakrishnan, Ranganath;
- Schaer, Tifany;
- Marger, Fabrice;
- Hovius, Ruud;
- Bertrand, Daniel;
- Pojer, Florence;
- Heinis, Christian
Publication type:
Article
Pyridomycin bridges the NADH- and substrate-binding pockets of the enoyl reductase InhA.
Published in:
Nature Chemical Biology, 2014, v. 10, n. 2, p. 96, doi. 10.1038/nchembio.1405
By:
- Hartkoorn, Ruben C;
- Pojer, Florence;
- Read, Jon A;
- Gingell, Helen;
- Neres, João;
- Horlacher, Oliver P;
- Altmann, Karl-Heinz;
- Cole, Stewart T
Publication type:
Article
Discovery and characterization of a marine bacterial SAM-dependent chlorinase.
Published in:
Nature Chemical Biology, 2008, v. 4, n. 1, p. 69, doi. 10.1038/nchembio.2007.56
By:
- Eustáquio, Alessandra S;
- Pojer, Florence;
- Noel, Joseph P;
- Moore, Bradley S
Publication type:
Article
Selective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17920-z
By:
- La Sala, Grégory;
- Michiels, Camille;
- Kükenshöner, Tim;
- Brandstoetter, Tania;
- Maurer, Barbara;
- Koide, Akiko;
- Lau, Kelvin;
- Pojer, Florence;
- Koide, Shohei;
- Sexl, Veronika;
- Dumoutier, Laure;
- Hantschel, Oliver
Publication type:
Article
Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16128-5
By:
- Duarte, Daniel P.;
- Lamontanara, Allan J.;
- La Sala, Giuseppina;
- Jeong, Sukyo;
- Sohn, Yoo-Kyoung;
- Panjkovich, Alejandro;
- Georgeon, Sandrine;
- Kükenshöner, Tim;
- Marcaida, Maria J.;
- Pojer, Florence;
- De Vivo, Marco;
- Svergun, Dmitri;
- Kim, Hak-Sung;
- Dal Peraro, Matteo;
- Hantschel, Oliver
Publication type:
Article
Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range.
Published in:
PLoS Pathogens, 2023, v. 18, n. 4, p. 1, doi. 10.1371/journal.ppat.1011206
By:
- Ni, Dongchun;
- Turelli, Priscilla;
- Beckert, Bertrand;
- Nazarov, Sergey;
- Uchikawa, Emiko;
- Myasnikov, Alexander;
- Pojer, Florence;
- Trono, Didier;
- Stahlberg, Henning;
- Lau, Kelvin
Publication type:
Article

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