OpenURL Connection Search

Select item for more details and to access through your institution.

Phase I pharmacological study of continuous chronomodulated capecitabine treatment.
Published in:
Pharmaceutical Research, 2020, v. 37, n. 5, p. 1, doi. 10.1007/s11095-020-02828-6
By:
- Roosendaal, Jeroen;
- Jacobs, Bart A. W.;
- Pluim, Dick;
- Rosing, Hilde;
- de Vries, Niels;
- van Werkhoven, Erik;
- Nuijen, Bastiaan;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Schellens, Jan H. M.;
- Marchetti, Serena
Publication type:
Article
Pharmacodynamic assay of thymidylate synthase activity in peripheral blood mononuclear cells.
Published in:
Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 8, p. 2495, doi. 10.1007/s00216-012-6676-1
By:
- Pluim, Dick;
- Schilders, Kim;
- Jacobs, Bart;
- Vaartjes, Daniëlle;
- Beijnen, Jos;
- Schellens, Jan
Publication type:
Article
Correction of peripheral blood mononuclear cell cytosolic protein for hemoglobin contamination.
Published in:
Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 7, p. 2391, doi. 10.1007/s00216-012-6614-2
By:
- Pluim, Dick;
- Jacobs, Bart;
- Krähenbühl, Martin;
- Ruijter, Anna;
- Beijnen, Jos;
- Schellens, Jan
Publication type:
Article
Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.
Published in:
Investigational New Drugs, 2015, v. 33, n. 1, p. 201, doi. 10.1007/s10637-014-0179-1
By:
- Leijen, Suzanne;
- Burgers, Sjaak;
- Baas, Paul;
- Pluim, Dick;
- Tibben, Matthijs;
- Werkhoven, Erik;
- Alessio, Enzo;
- Sava, Gianni;
- Beijnen, Jos;
- Schellens, Jan
Publication type:
Article
'Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183'.
Published in:
Investigational New Drugs, 2014, v. 32, n. 6, p. 1083, doi. 10.1007/s10637-014-0143-0
By:
- Marchetti, Serena;
- Pluim, Dick;
- Beijnen, Jos;
- Mazzanti, Roberto;
- Tellingen, Olaf;
- Schellens, Jan
Publication type:
Article
Food‐effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers.
Published in:
British Journal of Clinical Pharmacology, 2018, v. 84, n. 12, p. 2761, doi. 10.1111/bcp.13719
By:
- Henricks, Linda M.;
- Jacobs, Bart A. W.;
- Meulendijks, Didier;
- Pluim, Dick;
- Broek, Daan;
- Vries, Niels;
- Rosing, Hilde;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Guchelaar, Henk‐Jan;
- Cats, Annemieke;
- Schellens, Jan H. M.
Publication type:
Article
Pronounced between-subject and circadian variability in thymidylate synthase and dihydropyrimidine dehydrogenase enzyme activity in human volunteers.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 82, n. 3, p. 706, doi. 10.1111/bcp.13007
By:
- Jacobs, Bart A. W.;
- Deenen, Maarten J.;
- Pluim, Dick;
- Hasselt, J. G. Coen;
- Krähenbühl, Martin D.;
- Geel, Robin M. J. M.;
- Vries, Niels;
- Rosing, Hilde;
- Meulendijks, Didier;
- Burylo, Artur M.;
- Cats, Annemieke;
- Beijnen, Jos H.;
- Huitema, Alwin D. R.;
- Schellens, Jan H. M.
Publication type:
Article
Multiparameter Flow Cytometry Assay for Quantification of Immune Cell Subsets, PD‐1 Expression Levels and PD‐1 Receptor Occupancy by Nivolumab and Pembrolizumab.
Published in:
Cytometry. Part A, 2019, v. 95, n. 10, p. 1053, doi. 10.1002/cyto.a.23873
By:
- Pluim, Dick;
- Ros, Willeke;
- Miedema, Iris H. C.;
- Beijnen, Jos H.;
- Schellens, Jan H. M.
Publication type:
Article
Validation of a multiparameter flow cytometry method for the determination of phosphorylated extracellular-signal-regulated kinase and DNA in circulating tumor cells.
Published in:
Cytometry. Part A, 2012, v. 81A, n. 8, p. 664, doi. 10.1002/cyto.a.22049
By:
- Pluim, Dick;
- Devriese, Lot A.;
- Beijnen, Jos H.;
- Schellens, Jan H. M.
Publication type:
Article
Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA.
Published in:
Investigational New Drugs, 2013, v. 31, n. 5, p. 1125, doi. 10.1007/s10637-013-9923-1
By:
- Marchetti, Serena;
- Pluim, Dick;
- Eijndhoven, Monique;
- Tellingen, Olaf;
- Mazzanti, Roberto;
- Beijnen, Jos;
- Schellens, Jan
Publication type:
Article
Erratum to: Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA.
Published in:
2013
By:
- Marchetti, Serena;
- Pluim, Dick;
- Eijndhoven, Monique;
- Tellingen, Olaf;
- Mazzanti, Roberto;
- Beijnen, Jos;
- Schellens, Jan
Publication type:
Correction Notice
Human metabolism of [14C]indisulam following i.v. infusion in cancer patients.
Published in:
Investigational New Drugs, 2005, v. 23, n. 4, p. 317, doi. 10.1007/s10637-005-1440-4
By:
- Jan-Hendrik Beumer;
- Michel J. X. Hillebrand;
- Dick Pluim;
- Hilde Rosing;
- Karen Foley;
- S. Murray Yule;
- Jan H. M. Schellens;
- Jos H. Beijnen
Publication type:
Article
Dihydrofolate Reductase/Thymidylate Synthase Fine-Tunes the Folate Status and Controls Redox Homeostasis in Plants.
Published in:
Plant Cell, 2017, v. 29, n. 11, p. 2831, doi. 10.1105/tpc.17.00433
By:
- Gorelova, Vera;
- Lepeleire, Jolien De;
- Daele, Jeroen Van;
- Pluim, Dick;
- Meï, Coline;
- Cuypers, Ann;
- Leroux, Olivier;
- Rébeillé, Fabrice;
- Schellens, Jan H.M.;
- Blancquaert, Dieter;
- Stove, Christophe P.;
- Straeten, Dominique Van Der
Publication type:
Article
EpCAM-based flow cytometry in cerebrospinal fluid greatly improves diagnostic accuracy of leptomeningeal metastases from epithelial tumors.
Published in:
Neuro-Oncology, 2016, v. 18, n. 6, p. 855, doi. 10.1093/neuonc/nov273
By:
- Kerklaan, Bojana Milojkovic;
- Pluim, Dick;
- Bol, Mijke;
- Hofland, Ingrid;
- Westerga, Johan;
- van Tinteren, Harm;
- Beijnen, Jos H.;
- Boogerd, Willem;
- Schellens, Jan H. M.;
- Brandsma, Dieta
Publication type:
Article
Adduct-specific monoclonal antibodies for the measurement of cisplatin-induced DNA lesions in individual cell nuclei.
Published in:
Nucleic Acids Research, 2006, v. 34, n. 6, p. e47, doi. 10.1093/nar/gkl051
By:
- Liedert, Bernd;
- Pluim, Dick;
- Schellens, Jan;
- Thomale, Jürgen
Publication type:
Article
Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT).
Published in:
International Journal of Cancer, 2006, v. 119, n. 4, p. 750, doi. 10.1002/ijc.21919
By:
- Hoebers, Frank J.P.;
- Pluim, Dick;
- Verheij, Marcel;
- Balm, Alfons J.M.;
- Bartelink, Harry;
- Schellens, Jan H.M.;
- Begg, Adrian C.
Publication type:
Article
Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 1, p. 62, doi. 10.1002/cpt.2608
By:
- de With, Mirjam;
- Knikman, Jonathan;
- de Man, Femke M.;
- Lunenburg, Carin A. T. C.;
- Henricks, Linda M.;
- van Kuilenburg, André B. P.;
- Maring, Jan G.;
- van Staveren, Maurice C.;
- de Vries, Niels;
- Rosing, Hilde;
- Beijnen, Jos H.;
- Pluim, Dick;
- Modak, Anil;
- Imholz, Alex L. T.;
- van Schaik, Ron H. N.;
- Schellens, Jan H. M.;
- Gelderblom, Hans;
- Cats, Annemieke;
- Guchelaar, Henk‐Jan;
- Mathijssen, Ron H. J.
Publication type:
Article
A phase 0 clinical trial of novel candidate extended-release formulations of capecitabine.
Published in:
2016
By:
- Jacobs, Bart;
- Meulenaar, Jelte;
- Rosing, Hilde;
- Pluim, Dick;
- Tibben, Matthijs;
- Vries, Niels;
- Nuijen, Bastiaan;
- Huitema, Alwin;
- Beijnen, Jos;
- Schellens, Jan;
- Marchetti, Serena;
- Jacobs, Bart A W;
- Tibben, Matthijs M;
- de Vries, Niels;
- Huitema, Alwin D R;
- Beijnen, Jos H;
- Schellens, Jan H M
Publication type:
journal article
Cytotoxicity of the organic ruthenium anticancer drug Nami-A is correlated with DNA binding in four different human tumor cell lines.
Published in:
Cancer Chemotherapy & Pharmacology, 2004, v. 54, n. 1, p. 71, doi. 10.1007/s00280-004-0773-6
By:
- Pluim, Dick;
- van Waardenburg, Robert C. A. M.;
- Beijnen, Jos H.;
- Schellens, Jan H. M.
Publication type:
Article
Systemic and tumor disposition of platinum after administration of cisplatin or STEALTH liposomal-cisplatin formulations (SPI-077 and SPI-077 B103) in a preclinical tumor model of melanoma.
Published in:
Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 4, p. 329, doi. 10.1007/s00280-003-0719-4
By:
- Zamboni, William C.;
- Gervais, Anne C.;
- Egorin, Merrill J.;
- Schellens, Jan H. M.;
- Zuhowski, Elleanor G.;
- Pluim, Dick;
- Joseph, Erin;
- Hamburger, Deborah R.;
- Working, Peter K.;
- Colbern, Gail;
- Tonda, Margaret E.;
- Potter, Douglas M.;
- Eiseman, Julie L.
Publication type:
Article
Phase I and pharmacokinetic study of SPI-77, a liposomal encapsulated dosage form of cisplatin.
Published in:
Cancer Chemotherapy & Pharmacology, 2002, v. 49, n. 3, p. 201, doi. 10.1007/s002800100371
By:
- Terwogt, Jetske M. Meerum;
- Groenewegen, Gerard;
- Pluim, Dick;
- Maliepaard, Marc;
- Tibben, Matthijs M.;
- Huisman, Albert;
- ten Bokkel Huinink, Wim W.;
- Schot, Margaret;
- Welbank, Helen;
- Voest, Emile E.;
- Beijnen, Jos H.;
- Schellens, Jan H. M.
Publication type:
Article
A Phase I dose‐escalation study of two cycles carboplatin‐olaparib followed by olaparib monotherapy in patients with advanced cancer.
Published in:
International Journal of Cancer, 2021, v. 148, n. 12, p. 3041, doi. 10.1002/ijc.33498
By:
- Geenen, Jill J. J.;
- Dackus, Gwen M. H. E.;
- Schouten, Philip C.;
- Pluim, Dick;
- Marchetti, Serena;
- Sonke, Gabe S.;
- Jóźwiak, Katarzyna;
- Huitema, Alwin D. R.;
- Beijnen, Jos H.;
- Schellens, Jan H. M.;
- Linn, Sabine C.
Publication type:
Article
Increased risk of severe fluoropyrimidine-associated toxicity in patients carrying a G to C substitution in the first 28-bp tandem repeat of the thymidylate synthase 2 R allele.
Published in:
International Journal of Cancer, 2016, v. 138, n. 1, p. 245, doi. 10.1002/ijc.29694
By:
- Meulendijks, Didier;
- Jacobs, Bart A.W.;
- Aliev, Abidin;
- Pluim, Dick;
- van Werkhoven, Erik;
- Deenen, Maarten J.;
- Beijnen, Jos H.;
- Cats, Annemieke;
- Schellens, Jan H.M.
Publication type:
Article
Is Higher Docetaxel Clearance in Prostate Cancer Patients Explained by Higher CYP3A? An In Vivo Phenotyping Study with Midazolam.
Published in:
Journal of Clinical Pharmacology, 2024, v. 64, n. 2, p. 155, doi. 10.1002/jcph.2362
By:
- van der Heijden, Lisa T.;
- Ribbers, Claire A.;
- Vermunt, Marit A.C.;
- Pluim, Dick;
- Acda, Manon;
- Tibben, Matthijs;
- Rosing, Hilde;
- Douma, Joeri A.J.;
- Naipal, Kishan;
- Bergman, Andre M.;
- Beijnen, Jos H.;
- Huitema, Alwin D.R.;
- Opdam, Frans L.
Publication type:
Article
Bevacizumab combined with docetaxel, oxaliplatin, and capecitabine, followed by maintenance with capecitabine and bevacizumab, as first-line treatment of patients with advanced HER2-negative gastric cancer: A multicenter phase 2 study.
Published in:
2016
By:
- Meulendijks, Didier;
- de Groot, Jan Willem B.;
- Los, Maartje;
- Boers, James E.;
- Beerepoot, Laurens V.;
- Polee, Marco B.;
- Beeker, Aart;
- Portielje, Johanna E.A.;
- Goey, Swan H.;
- de Jong, Robert S.;
- Vanhoutvin, Steven A.L.W.;
- Kuiper, Maria;
- Sikorska, Karolina;
- Pluim, Dick;
- Beijnen, Jos H.;
- Schellens, Jan H.M.;
- Grootscholten, Cecile;
- Tesselaar, Margot E.T.;
- Cats, Annemieke
Publication type:
journal article
EpCAM-based assays for epithelial tumor cell detection in cerebrospinal fluid.
Published in:
Journal of Neuro-Oncology, 2018, v. 137, n. 1, p. 1, doi. 10.1007/s11060-017-2691-6
By:
- van Bussel, Mark T. J.;
- Pluim, Dick;
- Bol, Mijke;
- Beijnen, Jos H.;
- Schellens, Jan H. M.;
- Brandsma, Dieta
Publication type:
Article

Found: 26