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Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.
Published in:
Angewandte Chemie, 2019, v. 131, n. 2, p. 525, doi. 10.1002/ange.201810179
By:
- Vazquez‐Rodriguez, Saleta;
- Wright, Miranda;
- Rogers, Catherine M.;
- Cribbs, Adam P.;
- Velupillai, Srikannathasan;
- Philpott, Martin;
- Lee, Henry;
- Dunford, James E.;
- Huber, Kilian V. M.;
- Robers, Matthew B.;
- Vasta, James D.;
- Thezenas, Marie‐Laetitia;
- Bonham, Sarah;
- Kessler, Benedikt;
- Bennett, James;
- Fedorov, Oleg;
- Raynaud, Florence;
- Donovan, Adam;
- Blagg, Julian;
- Bavetsias, Vassilios
Publication type:
Article
Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02246-7
By:
- Larrouture, Quitterie C.;
- Cribbs, Adam P.;
- Rao, Srinivasa R.;
- Philpott, Martin;
- Snelling, Sarah J.;
- Knowles, Helen J.
Publication type:
Article
Design, Synthesis and Characterization of Covalent KDM5 Inhibitors.
Published in:
Angewandte Chemie International Edition, 2019, v. 58, n. 2, p. 515, doi. 10.1002/anie.201810179
By:
- Vazquez‐Rodriguez, Saleta;
- Wright, Miranda;
- Rogers, Catherine M.;
- Cribbs, Adam P.;
- Velupillai, Srikannathasan;
- Philpott, Martin;
- Lee, Henry;
- Dunford, James E.;
- Huber, Kilian V. M.;
- Robers, Matthew B.;
- Vasta, James D.;
- Thezenas, Marie‐Laetitia;
- Bonham, Sarah;
- Kessler, Benedikt;
- Bennett, James;
- Fedorov, Oleg;
- Raynaud, Florence;
- Donovan, Adam;
- Blagg, Julian;
- Bavetsias, Vassilios
Publication type:
Article
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction.
Published in:
Angewandte Chemie International Edition, 2014, v. 53, n. 24, p. 6126, doi. 10.1002/anie.201402750
By:
- Rooney, Timothy P. C.;
- Filippakopoulos, Panagis;
- Fedorov, Oleg;
- Picaud, Sarah;
- Cortopassi, Wilian A.;
- Hay, Duncan A.;
- Martin, Sarah;
- Tumber, Anthony;
- Rogers, Catherine M.;
- Philpott, Martin;
- Wang, Minghua;
- Thompson, Amber L.;
- Heightman, Tom D.;
- Pryde, David C.;
- Cook, Andrew;
- Paton, Robert S.;
- Müller, Susanne;
- Knapp, Stefan;
- Brennan, Paul E.;
- Conway, Stuart J.
Publication type:
Article
Dietary Protection Against Free Radicals: A Case for Multiple Testing to Establish Structure-activity Relationships for Antioxidant Potential of Anthocyanic Plant Species.
Published in:
International Journal of Molecular Sciences, 2009, v. 10, n. 3, p. 1081, doi. 10.3390/ijms10031081
By:
- Philpott, Martin;
- Lim, Chiara Cheng;
- Ferguson, Lynnette R.
Publication type:
Article
Nanopore sequencing of single-cell transcriptomes with scCOLOR-seq.
Published in:
Nature Biotechnology, 2021, v. 39, n. 12, p. 1517, doi. 10.1038/s41587-021-00965-w
By:
- Philpott, Martin;
- Watson, Jonathan;
- Thakurta, Anjan;
- Brown Jr, Tom;
- Brown Sr, Tom;
- Oppermann, Udo;
- Cribbs, Adam P.
Publication type:
Article
A Series of Potent CREBBP Bromodomain Ligands Reveals an Induced-Fit Pocket Stabilized by a Cation-π Interaction.
Published in:
Angewandte Chemie, 2014, v. 126, n. 24, p. 6240, doi. 10.1002/ange.201402750
By:
- Rooney, Timothy P. C.;
- Filippakopoulos, Panagis;
- Fedorov, Oleg;
- Picaud, Sarah;
- Cortopassi, Wilian A.;
- Hay, Duncan A.;
- Martin, Sarah;
- Tumber, Anthony;
- Rogers, Catherine M.;
- Philpott, Martin;
- Wang, Minghua;
- Thompson, Amber L.;
- Heightman, Tom D.;
- Pryde, David C.;
- Cook, Andrew;
- Paton, Robert S.;
- Müller, Susanne;
- Knapp, Stefan;
- Brennan, Paul E.;
- Conway, Stuart J.
Publication type:
Article
The growing burden of long COVID in the United Kingdom: Insights from the UK Coronavirus Infection Survey.
Published in:
International Forum of Allergy & Rhinology, 2023, v. 13, n. 8, p. 1535, doi. 10.1002/alr.23103
By:
- Gokani, Shyam Ajay;
- Ta, Ngan Hong;
- Espehana, Andreas;
- Garden, Elizabeth Mairenn;
- Klyvyte, Gabija;
- Luke, Louis;
- Myuran, Tharsika;
- Uththerakunaseelan, Vinushy;
- Boak, Duncan Cameron;
- Philpott, Carl Martin
Publication type:
Article
Uncoupling gene–diet interactions in inflammatory bowel disease (IBD).
Published in:
Genes & Nutrition, 2007, v. 2, n. 1, p. 71, doi. 10.1007/s12263-007-0012-y
By:
- Ferguson, Lynnette;
- Peterman, Ivonne;
- Hübner, Claudia;
- Philpott, Martin;
- Shellin, Andrew
Publication type:
Article
Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival.
Published in:
Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-023-01335-6
By:
- Ozyerli-Goknar, Ezgi;
- Kala, Ezgi Yagmur;
- Aksu, Ali Cenk;
- Bulut, Ipek;
- Cingöz, Ahmet;
- Nizamuddin, Sheikh;
- Biniossek, Martin;
- Seker-Polat, Fidan;
- Morova, Tunc;
- Aztekin, Can;
- Kung, Sonia H. Y.;
- Syed, Hamzah;
- Tuncbag, Nurcan;
- Gönen, Mehmet;
- Philpott, Martin;
- Cribbs, Adam P.;
- Acilan, Ceyda;
- Lack, Nathan A.;
- Onder, Tamer T.;
- Timmers, H. T. Marc
Publication type:
Article
An individual-based versus group-based exercise and counselling intervention for improving quality of life in breast cancer survivors. A feasibility and efficacy study.
Published in:
Psycho-Oncology, 2012, v. 21, n. 10, p. 1136, doi. 10.1002/pon.2015
By:
- Naumann, Fiona;
- Munro, Aime;
- Martin, Eric;
- Magrani, Paula;
- Buchan, Jena;
- Smith, Cathie;
- Piggott, Ben;
- Philpott, Martin
Publication type:
Article
Sweetpotato antioxidant potential.
Published in:
Journal of the Science of Food & Agriculture, 2003, v. 83, n. 10, p. 1076, doi. 10.1002/jsfa.1504
By:
- Martin Philpott;
- Kevin S Gould;
- Kenneth R Markham;
- Steve L Lewthwaite;
- Lynnette R Ferguson
Publication type:
Article
Selective inhibition of BET bromodomains.
Published in:
Nature, 2010, v. 468, n. 7327, p. 1067, doi. 10.1038/nature09504
By:
- Filippakopoulos, Panagis;
- Jun Qi;
- Picaud, Sarah;
- Yao Shen;
- Smith, William B.;
- Fedorov, Oleg;
- Morse, Elizabeth M.;
- Keates, Tracey;
- Hickman, Tyler T.;
- Felletar, Ildiko;
- Philpott, Martin;
- Munro, Shonagh;
- McKeown, Michael R.;
- Yuchuan Wang;
- Christie, Amanda L.;
- West, Nathan;
- Cameron, Michael J.;
- Schwartz, Brian;
- Heightman, Tom D.;
- La Thangue, Nicholas
Publication type:
Article
Nucleotide-binding oligomerization domain containing 1 (NOD1) haplotypes and single nucleotide polymorphisms modify susceptibility to inflammatory bowel diseases in a New Zealand Caucasian population: a case-control study.
Published in:
BMC Research Notes, 2009, v. 2, p. 1, doi. 10.1186/1756-0500-2-52
By:
- Huebner, Claudia;
- Ferguson, Lynnette R.;
- Dug Yeo Han;
- Philpott, Martin;
- Barclay, Murray L.;
- Gearry, Richard B.;
- McCulloch, Alan;
- Demmers, Pieter S.;
- Browning, Brian L.
Publication type:
Article
Epigenetic events and protection from colon cancer in New Zealand.
Published in:
Environmental & Molecular Mutagenesis, 2004, v. 44, n. 1, p. 36
By:
- Lynnette R. Ferguson;
- Nishi Karunasinghe;
- Martin Philpott
Publication type:
Article
Interleukin-17A Causes Osteoarthritis-Like Transcriptional Changes in Human Osteoarthritis-Derived Chondrocytes and Synovial Fibroblasts In Vitro.
Published in:
Frontiers in Immunology, 2021, v. 12, p. N.PAG, doi. 10.3389/fimmu.2021.676173
By:
- Mimpen, Jolet Y.;
- Baldwin, Mathew J.;
- Cribbs, Adam P.;
- Philpott, Martin;
- Carr, Andrew J.;
- Dakin, Stephanie G.;
- Snelling, Sarah J.B.
Publication type:
Article
Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.626255
By:
- Cribbs, Adam P.;
- Filippakopoulos, Panagis;
- Philpott, Martin;
- Wells, Graham;
- Penn, Henry;
- Oerum, Henrik;
- Valge-Archer, Viia;
- Feldmann, Marc;
- Oppermann, Udo
Publication type:
Article
Assessment of COVID-19-related olfactory dysfunction and its association with psychological, neuropsychiatric, and cognitive symptoms.
Published in:
Frontiers in Neuroscience, 2023, p. 1, doi. 10.3389/fnins.2023.1165329
By:
- Jegatheeswaran, Lavandan;
- Gokani, Shyam Ajay;
- Luke, Louis;
- Klyvyte, Gabija;
- Espehana, Andreas;
- Garden, Elizabeth Mairenn;
- Tarantino, Alessia;
- Al Omari, Basil;
- Philpott, Carl Martin
Publication type:
Article
Effects of the serotonin receptor antagonist cyproheptadine on the activity and pharmacokinetics of 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
Published in:
2001
By:
- Zhao, Liangli;
- Kestell, Philip;
- Philpott, Martin;
- Ching, Lai-Ming;
- Zhuang, Li;
- Baguley, Bruce C.;
- Zhao, L;
- Kestell, P;
- Philpott, M;
- Ching, L M;
- Zhuang, L;
- Baguley, B C
Publication type:
journal article
Correction: Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.
Published in:
2023
By:
- Kurata, Keiji;
- James-Bott, Anna;
- Tye, Mark A.;
- Yamamoto, Leona;
- Samur, Mehmet K.;
- Tai, Yu-Tzu;
- Dunford, James;
- Johansson, Catrine;
- Senbabaoglu, Filiz;
- Philpott, Martin;
- Palmer, Charlotte;
- Ramasamy, Karthik;
- Gooding, Sarah;
- Smilova, Mihaela;
- Gaeta, Giorgia;
- Guo, Manman;
- Christianson, John C.;
- Payne, N. Connor;
- Singh, Kritika;
- Karagoz, Kubra
Publication type:
Correction Notice
Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma.
Published in:
Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00787-w
By:
- Kurata, Keiji;
- James-Bott, Anna;
- Tye, Mark A.;
- Yamamoto, Leona;
- Samur, Mehmet K.;
- Tai, Yu-Tzu;
- Dunford, James;
- Johansson, Catrine;
- Senbabaoglu, Filiz;
- Philpott, Martin;
- Palmer, Charlotte;
- Ramasamy, Karthik;
- Gooding, Sarah;
- Smilova, Mihaela;
- Gaeta, Giorgia;
- Guo, Manman;
- Christianson, John C.;
- Payne, N. Connor;
- Singh, Kritika;
- Karagoz, Kubra
Publication type:
Article
EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities.
Published in:
Cell Death & Disease, 2022, v. 13, n. 8, p. 1, doi. 10.1038/s41419-022-05146-4
By:
- Yedier-Bayram, Ozlem;
- Gokbayrak, Bengul;
- Kayabolen, Alisan;
- Aksu, Ali Cenk;
- Cavga, Ayse Derya;
- Cingöz, Ahmet;
- Kala, Ezgi Yagmur;
- Karabiyik, Goktug;
- Günsay, Rauf;
- Esin, Beril;
- Morova, Tunc;
- Uyulur, Fırat;
- Syed, Hamzah;
- Philpott, Martin;
- Cribbs, Adam P.;
- Kung, Sonia H. Y.;
- Lack, Nathan A.;
- Onder, Tamer T.;
- Bagci-Onder, Tugba
Publication type:
Article
AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation.
Published in:
Epigenetics & Chromatin, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13072-021-00406-7
By:
- Uğurlu-Çimen, Deniz;
- Odluyurt, Deniz;
- Sevinç, Kenan;
- Özkan-Küçük, Nazlı Ezgi;
- Özçimen, Burcu;
- Demirtaş, Deniz;
- Enüstün, Eray;
- Aztekin, Can;
- Philpott, Martin;
- Oppermann, Udo;
- Özlü, Nurhan;
- Önder, Tamer T.
Publication type:
Article
PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo.
Published in:
Scientific Reports, 2024, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-48652-x
By:
- Brown, Elizabeth J.;
- Balaguer-Lluna, Leire;
- Cribbs, Adam P.;
- Philpott, Martin;
- Campo, Leticia;
- Browne, Molly;
- Wong, Jong Fu;
- Oppermann, Udo;
- Carcaboso, Ángel M.;
- Bullock, Alex N.;
- Farnie, Gillian
Publication type:
Article
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20308-8
By:
- Lechner, Matt;
- Schartinger, Volker H.;
- Steele, Christopher D.;
- Nei, Wen Long;
- Ooft, Marc Lucas;
- Schreiber, Liesa-Marie;
- Pipinikas, Christodoulos P.;
- Chung, Grace Tin-Yun;
- Chan, Yuk Yu;
- Wu, Feng;
- To, Ka-Fai;
- Tsang, Chi Man;
- Pearce, Wayne;
- Morelli, Daniele;
- Philpott, Martin;
- Masterson, Liam;
- Nibhani, Reshma;
- Wells, Graham;
- Bell, Christopher G.;
- Koller, Julia
Publication type:
Article
Olfactory Disorders Questionnaire: Scaling severity of quality‐of‐life impact.
Published in:
Clinical Otolaryngology, 2023, v. 48, n. 2, p. 206, doi. 10.1111/coa.14017
By:
- Garden, Elizabeth Mairenn;
- Kumaresan, Kala;
- Clark, Allan;
- Philpott, Carl Martin
Publication type:
Article

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