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Development of CDK2 and CDK5 Dual Degrader TMX‐2172.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 33, p. 13969, doi. 10.1002/ange.202004087
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- Publication type:
- Article
Cancer patient survival can be parametrized to improve trial precision and reveal time-dependent therapeutic effects.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28410-9
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- Publication type:
- Article
Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks.
- Published in:
- BMC Systems Biology, 2012, v. 6, n. 1, p. 29, doi. 10.1186/1752-0509-6-29
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- Publication type:
- Article
The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.
- Published in:
- EMBO Journal, 2006, v. 25, n. 17, p. 4033, doi. 10.1038/sj.emboj.7601293
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- Publication type:
- Article
A dual role for Bub1 in the spindle checkpoint and chromosome congression.
- Published in:
- EMBO Journal, 2005, v. 24, n. 8, p. 1621, doi. 10.1038/sj.emboj.7600641
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- Publication type:
- Article
GRcalculator: an online tool for calculating and mining dose-response data.
- Published in:
- 2017
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- Publication type:
- journal article
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium.
- Published in:
- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03050-3
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- Publication type:
- Article
Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling.
- Published in:
- eLife, 2021, p. 1, doi. 10.7554/eLife.64251
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- Publication type:
- Article
Receptor-based mechanism of relative sensing and cell memory in mammalian signaling networks.
- Published in:
- eLife, 2020, p. 1, doi. 10.7554/eLife.50342
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- Publication type:
- Article
A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity.
- Published in:
- eLife, 2019, p. 1, doi. 10.7554/eLife.50036
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- Publication type:
- Article
Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.20873
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- Publication type:
- Article
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. W1, p. W449, doi. 10.1093/nar/gku476
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- Publication type:
- Article
Cancer patient survival can be parametrized to improve trial precision and reveal time-dependent therapeutic effects.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28410-9
- By:
- Publication type:
- Article
Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition.
- Published in:
- Science Signaling, 2018, v. 11, n. 520, p. 1, doi. 10.1126/scisignal.aal1601
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- Publication type:
- Article
Conservation of protein abundance patterns reveals the regulatory architecture of the EGFR-MAPK pathway.
- Published in:
- Science Signaling, 2016, v. 9, n. 436, p. 1, doi. 10.1126/scisignal.aaf0891
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- Publication type:
- Article
Intra- and Interdimeric Caspase-8 Self-Cleavage Controls Strength and Timing of CD95-Induced Apoptosis.
- Published in:
- Science Signaling, 2014, v. 7, n. 316, p. 1, doi. 10.1126/scisignal.2004738
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- Publication type:
- Article
Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2.
- Published in:
- Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00943-6
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- Publication type:
- Article
Publisher Correction: Single-sequence protein structure prediction using a language model and deep learning.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Single-sequence protein structure prediction using a language model and deep learning.
- Published in:
- Nature Biotechnology, 2022, v. 40, n. 11, p. 1617, doi. 10.1038/s41587-022-01432-w
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- Publication type:
- Article
Alternative drug sensitivity metrics improve preclinical cancer pharmacogenomics.
- Published in:
- Nature Biotechnology, 2017, v. 35, n. 6, p. 500, doi. 10.1038/nbt.3882
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- Publication type:
- Article
Microfluidics closes in on point-of-care assays.
- Published in:
- Nature Biotechnology, 2008, v. 26, n. 12, p. 1345, doi. 10.1038/nbt1208-1345
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- Publication type:
- Article
A multiscale statistical mechanical framework integrates biophysical and genomic data to assemble cancer networks.
- Published in:
- Nature Genetics, 2014, v. 46, n. 12, p. 1363, doi. 10.1038/ng.3138
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- Publication type:
- Article
Adaptive informatics for multifactorial and high-content biological data.
- Published in:
- Nature Methods, 2011, v. 8, n. 6, p. 487, doi. 10.1038/nmeth.1600
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- Publication type:
- Article
The yeast DASH complex forms closed rings on microtubules.
- Published in:
- Nature Structural & Molecular Biology, 2005, v. 12, n. 2, p. 138, doi. 10.1038/nsmb896
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- Publication type:
- Article
Stitching and registering highly multiplexed whole-slide images of tissues and tumors using ASHLAR.
- Published in:
- Bioinformatics, 2022, v. 38, n. 19, p. 4613, doi. 10.1093/bioinformatics/btac544
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- Publication type:
- Article
Collecting and organizing systematic sets of protein data.
- Published in:
- Nature Reviews Molecular Cell Biology, 2006, v. 7, n. 11, p. 803, doi. 10.1038/nrm2042
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- Publication type:
- Article
Analysis of kinesin motor function at budding yeast kinetochores.
- Published in:
- Journal of Cell Biology, 2006, v. 172, n. 6, p. 861, doi. 10.1083/jcb.200509101
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- Publication type:
- Article
Spindle checkpoint proteins and chromosome--microtubule attachment in budding yeast.
- Published in:
- Journal of Cell Biology, 2004, v. 164, n. 4, p. 535, doi. 10.1083/jcb.200308100
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- Publication type:
- Article
Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-44778-2
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- Publication type:
- Article
GeneWalk identifies relevant gene functions for a biological context using network representation learning.
- Published in:
- Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02264-8
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- Publication type:
- Article
Decision-Tree Based Model Analysis for Efficient Identification of Parameter Relations Leading to Different Signaling States.
- Published in:
- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082593
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- Publication type:
- Article
Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges.
- Published in:
- PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0009202
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- Publication type:
- Article
Roles for the Conserved Spc105p/Kre28p Complex in Kinetochore-Microtubule Binding and the Spindle Assembly Checkpoint.
- Published in:
- PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007640
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- Publication type:
- Article
Integrating multi-omics data reveals function and therapeutic potential of deubiquitinating enzymes.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.72879
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- Publication type:
- Article
The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.
- Published in:
- 2009
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- Publication type:
- Erratum
Systematic calibration of a cell signaling network model.
- Published in:
- BMC Bioinformatics, 2010, v. 11, p. 202, doi. 10.1186/1471-2105-11-202
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- Publication type:
- Article
Fides: Reliable trust-region optimization for parameter estimation of ordinary differential equation models.
- Published in:
- PLoS Computational Biology, 2022, v. 18, n. 7, p. 1, doi. 10.1371/journal.pcbi.1010322
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- Publication type:
- Article
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.
- Published in:
- Nature, 2009, v. 459, n. 7245, p. 428, doi. 10.1038/nature08012
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- Publication type:
- Article
Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities.
- Published in:
- Nature, 2007, v. 446, n. 7138, p. 876, doi. 10.1038/nature05694
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- Publication type:
- Article
Cells on chips.
- Published in:
- Nature, 2006, v. 442, n. 7101, p. 403, doi. 10.1038/nature05063
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- Publication type:
- Article
A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.
- Published in:
- Nature Cell Biology, 2007, v. 9, n. 5, p. 556, doi. 10.1038/ncb1569
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- Publication type:
- Article
Physicochemical modelling of cell signalling pathways.
- Published in:
- Nature Cell Biology, 2006, v. 8, n. 11, p. 1195, doi. 10.1038/ncb1497
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- Publication type:
- Article
A role for the Adenomatous Polyposis Coli protein in chromosome segregation.
- Published in:
- Nature Cell Biology, 2001, v. 3, n. 4, p. 429, doi. 10.1038/35070123
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- Publication type:
- Article
Personal Protective Equipment for COVID-19: Distributed Fabrication and Additive Manufacturing.
- Published in:
- American Journal of Public Health, 2020, v. 110, n. 8, p. 1162, doi. 10.2105/AJPH.2020.305753
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- Publication type:
- Article
Mechanistic model of MAPK signaling reveals how allostery and rewiring contribute to drug resistance.
- Published in:
- Molecular Systems Biology, 2023, v. 19, n. 2, p. 1, doi. 10.15252/msb.202210988
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- Publication type:
- Article
Automated assembly of molecular mechanisms at scale from text mining and curated databases.
- Published in:
- Molecular Systems Biology, 2023, v. 19, n. 5, p. 1, doi. 10.15252/msb.202211325
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- Publication type:
- Article
From word models to executable models of signaling networks using automated assembly.
- Published in:
- Molecular Systems Biology, 2017, v. 13, n. 11, p. 1, doi. 10.15252/msb.20177651
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- Publication type:
- Article
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state.
- Published in:
- Molecular Systems Biology, 2017, v. 13, n. 1, p. n/a, doi. 10.15252/msb.20166796
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- Publication type:
- Article
Fractional killing arises from cell-to-cell variability in overcoming a caspase activity threshold.
- Published in:
- Molecular Systems Biology, 2015, v. 11, n. 5, p. n/a, doi. 10.15252/msb.20145584
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- Publication type:
- Article
Systematic analysis of BRAF<sup>V</sup><sup>600E</sup> melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis.
- Published in:
- Molecular Systems Biology, 2015, v. 11, n. 3, p. n/a, doi. 10.15252/msb.20145877
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- Publication type:
- Article