Found: 72
Select item for more details and to access through your institution.
DNA Binding of Benzo[a]pyrene Metabolites.
- Published in:
- Pharmacology, 1980, v. 20, n. 3, p. 137, doi. 10.1159/000137357
- By:
- Publication type:
- Article
Genetic Differences in the Metabolic Activation of Benzo[a]Pyrene in Mice.
- Published in:
- Pharmacology, 1979, v. 18, n. 6, p. 281, doi. 10.1159/000137267
- By:
- Publication type:
- Article
Significant interspecies differences in induction profiles of hepatic CYP enzymes by TCDD in bank and field voles.
- Published in:
- Environmental Toxicology & Chemistry, 2012, v. 31, n. 3, p. 663, doi. 10.1002/etc.1737
- By:
- Publication type:
- Article
Effects of Ospemifene on Drug Metabolism Mediated by Cytochrome P450 Enzymes in Humans in Vitro and in Vivo.
- Published in:
- International Journal of Molecular Sciences, 2013, v. 14, n. 7, p. 14064, doi. 10.3390/ijms140714064
- By:
- Publication type:
- Article
US regulations to curb alleged cancer causes are ineffectual and compromised by scientific, constitutional and ethical violations.
- Published in:
- Archives of Toxicology, 2023, v. 97, n. 6, p. 1813, doi. 10.1007/s00204-022-03429-5
- By:
- Publication type:
- Article
Aryl hydrocarbon hydroxylase in lymphocytes and lung tissue from lung cancer patients and controls.
- Published in:
- International Journal of Cancer, 1987, v. 39, n. 5, p. 565, doi. 10.1002/ijc.2910390505
- By:
- Publication type:
- Article
Effects of cytochrome P450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene.
- Published in:
- Biopharmaceutics & Drug Disposition, 2013, v. 34, n. 7, p. 387, doi. 10.1002/bdd.1853
- By:
- Publication type:
- Article
In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies.
- Published in:
- Journal of Mass Spectrometry, 2007, v. 42, n. 7, p. 960, doi. 10.1002/jms.1239
- By:
- Publication type:
- Article
Effect of clopidogrel and ticlopidine on cytochrome P450 2B6 activity as measured by bupropion hydroxylation
- Published in:
- Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 6, p. 553, doi. 10.1016/j.clpt.2005.02.010
- By:
- Publication type:
- Article
Marked effect of liver and kidney function on the pharmacokinetics of selegiline.
- Published in:
- Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 1, p. 54, doi. 10.1016/j.clpt.2004.09.004
- By:
- Publication type:
- Article
Inhibition of cytochrome P450 2B6 activity by hormone replacement therapy and oral contraceptive as measured by bupropion hydroxylation.
- Published in:
- Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 4, p. 326, doi. 10.1016/S0009-9236(03)00202-9
- By:
- Publication type:
- Article
CYP2D6 polymorphism is not crucial for the disposition of selegiline<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 4, p. 402, doi. 10.1016/S0009-9236(98)90071-6
- By:
- Publication type:
- Article
Age and cytochrome P450-linked drug metabolism in humans: An analysis of 226 subjects with equal histopathologic conditions<sup>*</sup>.
- Published in:
- Clinical Pharmacology & Therapeutics, 1997, v. 61, n. 3, p. 331, doi. 10.1016/S0009-9236(97)90166-1
- By:
- Publication type:
- Article
Effects of heme arginate on cytochrome P450-mediated metabolism of drugs in patients with variegate porphyria and in healthy men.
- Published in:
- Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 1, p. 9, doi. 10.1038/clpt.1994.94
- By:
- Publication type:
- Article
The evaluation of the drug-metabolizing capacity in patients with diabetes mellitus.
- Published in:
- 1980
- By:
- Publication type:
- journal article
Induction and Regulation of Xenobiotic-Metabolizing Cytochrome P450s in the Human A549 Lung Adenocarcinoma Cell Line.
- Published in:
- American Journal of Respiratory Cell & Molecular Biology, 2000, v. 22, n. 3, p. 360, doi. 10.1165/ajrcmb.22.3.3845
- By:
- Publication type:
- Article
Tandem mass spectrometric analysis of S- and N-linked glutathione conjugates of pulegone and menthofuran and identification of P450 enzymes mediating their formation.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2016, v. 30, n. 7, p. 917, doi. 10.1002/rcm.7518
- By:
- Publication type:
- Article
ADMET in Drug Development: What is the Role of Animals between In Silico -- In vitro and In Vivo Humans?
- Published in:
- Acta Pharmaceutica Hungarica, 2021, v. 91, n. 3/4, p. 144, doi. 10.33892/aph.2021.91.144-145
- By:
- Publication type:
- Article
Rapid detection and characterization of reactive drug metabolites in vitro using several isotope-labeled trapping agents and ultra-performance liquid chromatography/time-of-flight mass spectrometry.
- Published in:
- Rapid Communications in Mass Spectrometry: RCM, 2009, v. 23, n. 6, p. 843, doi. 10.1002/rcm.3953
- By:
- Publication type:
- Article
Detection of mRNA encoding xenobiotic-metabolizing cytochrome P450s in human bronchoalveolar macrophages and peripheral blood lymphocytes.
- Published in:
- Molecular Carcinogenesis, 1997, v. 20, n. 2, p. 224, doi. 10.1002/(SICI)1098-2744(199710)20:2<224::AID-MC9>3.0.CO;2-M
- By:
- Publication type:
- Article
Cytochromes P450, induction and cholesterol—what are the connections?
- Published in:
- 2008
- By:
- Publication type:
- Editorial
In vitro prediction of gastrointestinal absorption and bioavailability: an experts' meeting report.
- Published in:
- European Journal of Clinical Pharmacology, 2001, v. 57, n. 9, p. 621, doi. 10.1007/s002280100369
- By:
- Publication type:
- Article
Drug Metabolism - From In Vitro to In Vivo, From Simple to Complex.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2015, v. 117, n. 3, p. 147, doi. 10.1111/bcpt.12429
- By:
- Publication type:
- Article
Metabolism of Ophthalmic Timolol: New Aspects of an Old Drug.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2011, v. 108, n. 5, p. 297, doi. 10.1111/j.1742-7843.2011.00694.x
- By:
- Publication type:
- Article
Effects of Selective Serotonin Reuptake Inhibitors on Timolol Metabolism in Human Liver Microsomes and Cryo-Preserved Hepatocytes.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2010, v. 106, n. 4, p. 302, doi. 10.1111/j.1742-7843.2009.00487.x
- By:
- Publication type:
- Article
Prediction of Drug Metabolism and Interactions on the Basis ofin vitroInvestigations.
- Published in:
- Basic & Clinical Pharmacology & Toxicology, 2005, v. 96, n. 3, p. 167, doi. 10.1111/j.1742-7843.2005.pto960305.x
- By:
- Publication type:
- Article
Metabolism and metabolite profiles in vitro and in vivo of ospemifene in humans and preclinical species.
- Published in:
- Drug Metabolism & Personalized Therapy, 2016, v. 31, n. 1, p. 35, doi. 10.1515/dmpt-2015-0020
- By:
- Publication type:
- Article
Effect of renal impairment on the pharmacokinetics of bupropion and its metabolites.
- Published in:
- British Journal of Clinical Pharmacology, 2007, v. 64, n. 2, p. 165, doi. 10.1111/j.1365-2125.2007.02866.x
- By:
- Publication type:
- Article
Polymorphisms of CYP2A6 and its practical consequences.
- Published in:
- British Journal of Clinical Pharmacology, 2001, v. 52, n. 4, p. 357, doi. 10.1046/j.0306-5251.2001.01500.x
- By:
- Publication type:
- Article
In vivo-in vitro-in silico pharmacokinetic modelling in drug development: current status and future directions.
- Published in:
- 2011
- By:
- Publication type:
- journal article
In Vivo-In Vitro-In Silico Pharmacokinetic Modelling in Drug Development.
- Published in:
- Clinical Pharmacokinetics, 2011, v. 50, n. 8, p. 483, doi. 10.2165/11592400-000000000-00000
- By:
- Publication type:
- Article
Scientifically unfounded precaution drives European Commission’s recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles.
- Published in:
- Altex, 2013, v. 30, n. 3, p. 381, doi. 10.14573/altex.2013.3.381
- By:
- Publication type:
- Article
Independent Induction and Inhibition of Ornithine Decarboxylase and Aryl Hydrocarbon Hydroxylase Activities in Rat Epidermis.
- Published in:
- 1982
- By:
- Publication type:
- Report
The EU chemicals strategy for sustainability: in support of the BfR position.
- Published in:
- 2021
- By:
- Publication type:
- Letter
Inhibition and induction of CYP enzymes in humans: an update.
- Published in:
- Archives of Toxicology, 2020, v. 94, n. 11, p. 3671, doi. 10.1007/s00204-020-02936-7
- By:
- Publication type:
- Article
CYP-associated drug–drug interactions: A mission accomplished?
- Published in:
- 2020
- By:
- Publication type:
- Editorial
Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity: how to evaluate the risk of the S-EDCs?
- Published in:
- 2020
- By:
- Publication type:
- Editorial
Integration of epidemiological findings with mechanistic evidence in regulatory pesticide risk assessment: EFSA experiences.
- Published in:
- Archives of Toxicology, 2019, v. 93, n. 6, p. 1779, doi. 10.1007/s00204-019-02467-w
- By:
- Publication type:
- Article
Chemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research.
- Published in:
- Archives of Toxicology, 2017, v. 91, n. 8, p. 2763, doi. 10.1007/s00204-017-1986-x
- By:
- Publication type:
- Article
Open letter to the European commission: scientifically unfounded precaution drives European commission's recommendations on EDC regulation, while defying common sense, well-established science, and risk assessment principles.
- Published in:
- 2013
- By:
- Publication type:
- Letter
Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.
- Published in:
- Archives of Toxicology, 2011, v. 85, n. 5, p. 367, doi. 10.1007/s00204-011-0693-2
- By:
- Publication type:
- Article
Inhibition and induction of human cytochrome P450 enzymes: current status.
- Published in:
- Archives of Toxicology, 2008, v. 82, n. 10, p. 667, doi. 10.1007/s00204-008-0332-8
- By:
- Publication type:
- Article
Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo( a)pyrene as shown in the rat lung and liver.
- Published in:
- Archives of Toxicology, 2007, v. 81, n. 3, p. 169, doi. 10.1007/s00204-006-0135-8
- By:
- Publication type:
- Article
Impairment of drug metabolism in patients with liver cancer.
- Published in:
- European Journal of Clinical Investigation, 1977, v. 7, n. 4, p. 269, doi. 10.1111/j.1365-2362.1977.tb01604.x
- By:
- Publication type:
- Article
INVESTIGATION OF MECHANISM BASED INHIBITION OF CYP450 ENZYMES BY SELECTED ORGANOPHOSPHOROUS, PYRETHROIDS AND BENZOYL UREA PESTICIDES IN POOLED HUMAN LIVER MICROSOMES.
- Published in:
- Therapeutics, Pharmacology & Clinical Toxicology, 2011, v. 15, n. 3, p. 197
- By:
- Publication type:
- Article
Statement of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on the design and conduct of groundwater monitoring studies supporting groundwater exposure assessments of pesticides.
- Published in:
- EFSA Journal, 2023, v. 21, n. 5, p. 1, doi. 10.2903/j.efsa.2023.7990
- By:
- Publication type:
- Article
Development of adverse outcome pathways relevant for the identification of substances having endocrine disruption properties Uterine adenocarcinoma as adverse outcome.
- Published in:
- EFSA Journal, 2023, v. 21, n. 2, p. 1, doi. 10.2903/j.efsa.2023.7744
- By:
- Publication type:
- Article
Scientific opinion on toxicity of pyrethroid common metabolites.
- Published in:
- EFSA Journal, 2022, v. 20, n. 10, p. 1, doi. 10.2903/j.efsa.2022.7582
- By:
- Publication type:
- Article
Editorial: Relevance of dog studies for the derivation of health‐based guidance values for plant protection products approval.
- Published in:
- EFSA Journal, 2022, v. 20, n. 9, p. 1, doi. 10.2903/j.efsa.2022.e200923
- By:
- Publication type:
- Article
Statement on the active substance flupyradifurone.
- Published in:
- EFSA Journal, 2022, v. 20, n. 1, p. 1, doi. 10.2903/j.efsa.2022.7030
- By:
- Publication type:
- Article