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Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37648-w
By:
- Al-Sawaf, Othman;
- Zhang, Can;
- Jin, Hyun Yong;
- Robrecht, Sandra;
- Choi, Yoonha;
- Balasubramanian, Sandhya;
- Kotak, Alex;
- Chang, Yi Meng;
- Fink, Anna Maria;
- Tausch, Eugen;
- Schneider, Christof;
- Ritgen, Matthias;
- Kreuzer, Karl-Anton;
- Chyla, Brenda;
- Paulson, Joe;
- Pallasch, Christian P.;
- Frenzel, Lukas P.;
- Peifer, Martin;
- Eichhorst, Barbara;
- Stilgenbauer, Stephan
Publication type:
Article
Hybrid optimization method with general switching strategy for parameter estimation.
Published in:
BMC Systems Biology, 2008, v. 2, p. 1, doi. 10.1186/1752-0509-2-26
By:
- Balsa-Canto, Eva;
- Peifer, Martin;
- Banga, Julio R.;
- Timmer, Jens;
- Fleck, Christian
Publication type:
Article
Genomic and transcriptomic heterogeneity of colorectal tumours arising in Lynch syndrome.
Published in:
Journal of Pathology, 2017, v. 243, n. 2, p. 242, doi. 10.1002/path.4948
By:
- Binder, Hans;
- Hopp, Lydia;
- Schweiger, Michal R;
- Hoffmann, Steve;
- Jühling, Frank;
- Kerick, Martin;
- Timmermann, Bernd;
- Siebert, Susann;
- Grimm, Christina;
- Nersisyan, Lilit;
- Arakelyan, Arsen;
- Herberg, Maria;
- Buske, Peter;
- Loeffler‐Wirth, Henry;
- Rosolowski, Maciej;
- Engel, Christoph;
- Przybilla, Jens;
- Peifer, Martin;
- Friedrichs, Nicolaus;
- Moeslein, Gabriela
Publication type:
Article
Deep learning for sensitive detection of Helicobacter Pylori in gastric biopsies.
Published in:
2020
By:
- Klein, Sebastian;
- Gildenblat, Jacob;
- Ihle, Michaele Angelika;
- Merkelbach-Bruse, Sabine;
- Noh, Ka-Won;
- Peifer, Martin;
- Quaas, Alexander;
- Büttner, Reinhard
Publication type:
journal article
Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.
Published in:
2013
By:
- Chatterjee, Sampurna;
- Heukamp, Lukas C;
- Siobal, Maike;
- Schöttle, Jakob;
- Wieczorek, Caroline;
- Peifer, Martin;
- Frasca, Davide;
- Koker, Mirjam;
- König, Katharina;
- Meder, Lydia;
- Rauh, Daniel;
- Buettner, Reinhard;
- Wolf, Jürgen;
- Brekken, Rolf A;
- Neumaier, Bernd;
- Christofori, Gerhard;
- Thomas, Roman K;
- Ullrich, Roland T
Publication type:
journal article
Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 4, p. 1732, doi. 10.1172/JCI65385
By:
- Chatterjee, Sampurna;
- Heukamp, Lukas C.;
- Siobal, Maike;
- Schöttle, Jakob;
- Wieczorek, Caroline;
- Peifer, Martin;
- Frasca, Davide;
- Koker, Mirjam;
- König, Katharina;
- Meder, Lydia;
- Rauh, Daniel;
- Buettner, Reinhard;
- Wolf, Jürgen;
- Brekken, Rolf A.;
- Neumaier, Bernd;
- Christofori, Gerhard;
- Thomas, Roman K.;
- Ullrich, Roland T.
Publication type:
Article
Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 3, p. 1732, doi. 10.1172/JCI65385
By:
- Chatterjee, Sampurna;
- Heukamp, Lukas C.;
- Siobal, Maike;
- Schöttle, Jakob;
- Wieczorek, Caroline;
- Peifer, Martin;
- Frasca, Davide;
- Koker, Mirjam;
- König, Katharina;
- Meder, Lydia;
- Rauh, Daniel;
- Buettner, Reinhard;
- Wolf, Jürgen;
- Brekken, Rolf A.;
- Neumaier, Bernd;
- Christofori, Gerhard;
- Thomas, Roman K.;
- Ullrich, Roland T.
Publication type:
Article
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.
Published in:
2009
By:
- Sos, Martin L.;
- Michel, Kathrin;
- Zander, Thomas;
- Weiss, Jonathan;
- Frommolt, Peter;
- Peifer, Martin;
- Danan Li;
- Ullrich, Roland;
- Koker, Mirjam;
- Fischer, Florian;
- Shimamura, Takeshi;
- Rauh, Daniel;
- Mermel, Craig;
- Fischer, Stefanie;
- Stückrath, Isabel;
- Heynck, Stefanie;
- Beroukhim, Rameen;
- Lin, William;
- Winckler, Wendy;
- Shah, Kinjal
Publication type:
journal article
Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer.
Published in:
Nucleic Acids Research, 2010, v. 38, n. 20, p. 6985, doi. 10.1093/nar/gkq579
By:
- Chmielecki, Juliann;
- Peifer, Martin;
- Jia, Peilin;
- Socci, Nicholas D.;
- Hutchinson, Katherine;
- Viale, Agnes;
- Zhao, Zhongming;
- Thomas, Roman K.;
- Pao, William
Publication type:
Article
Reliable assessment of telomere maintenance mechanisms in neuroblastoma.
Published in:
Cell & Bioscience, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s13578-022-00896-2
By:
- Meeser, Alina;
- Bartenhagen, Christoph;
- Werr, Lisa;
- Hellmann, Anna-Maria;
- Kahlert, Yvonne;
- Hemstedt, Nadine;
- Nürnberg, Peter;
- Altmüller, Janine;
- Ackermann, Sandra;
- Hero, Barbara;
- Simon, Thorsten;
- Peifer, Martin;
- Fischer, Matthias;
- Rosswog, Carolina
Publication type:
Article
A crucial requirement for Hedgehog signaling in small cell lung cancer.
Published in:
Nature Medicine, 2011, v. 17, n. 11, p. 1504, doi. 10.1038/nm.2473
By:
- Park, Kwon-Sik;
- Martelotto, Luciano G;
- Peifer, Martin;
- Sos, Martin L;
- Karnezis, Anthony N;
- Mahjoub, Moe R;
- Bernard, Katie;
- Conklin, Jamie F;
- Szczepny, Anette;
- Yuan, Jing;
- Guo, Ribo;
- Ospina, Beatrice;
- Falzon, Jeanette;
- Bennett, Samara;
- Brown, Tracey J;
- Markovic, Ana;
- Devereux, Wendy L;
- Ocasio, Cory A;
- Chen, James K;
- Stearns, Tim
Publication type:
Article
Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.
Published in:
Nature Genetics, 2012, v. 44, n. 10, p. 1104, doi. 10.1038/ng.2396
By:
- Peifer, Martin;
- Fernández-Cuesta, Lynnette;
- Sos, Martin L;
- George, Julie;
- Seidel, Danila;
- Kasper, Lawryn H;
- Plenker, Dennis;
- Leenders, Frauke;
- Sun, Ruping;
- Zander, Thomas;
- Menon, Roopika;
- Koker, Mirjam;
- Dahmen, Ilona;
- Müller, Christian;
- Di Cerbo, Vincenzo;
- Schildhaus, Hans-Ulrich;
- Altmüller, Janine;
- Baessmann, Ingelore;
- Becker, Christian;
- de Wilde, Bram
Publication type:
Article
Author Correction: Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia.
Published in:
2023
By:
- Al-Sawaf, Othman;
- Zhang, Can;
- Jin, Hyun Yong;
- Robrecht, Sandra;
- Choi, Yoonha;
- Balasubramanian, Sandhya;
- Kotak, Alex;
- Chang, Yi Meng;
- Fink, Anna Maria;
- Tausch, Eugen;
- Schneider, Christof;
- Ritgen, Matthias;
- Kreuzer, Karl-Anton;
- Chyla, Brenda;
- Paulson, Joseph N.;
- Pallasch, Christian P.;
- Frenzel, Lukas P.;
- Peifer, Martin;
- Eichhorst, Barbara;
- Stilgenbauer, Stephan
Publication type:
Correction Notice
Transcriptomic profiles and 5-year results from the randomized CLL14 study of venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab in chronic lymphocytic leukemia.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37648-w
By:
- Al-Sawaf, Othman;
- Zhang, Can;
- Jin, Hyun Yong;
- Robrecht, Sandra;
- Choi, Yoonha;
- Balasubramanian, Sandhya;
- Kotak, Alex;
- Chang, Yi Meng;
- Fink, Anna Maria;
- Tausch, Eugen;
- Schneider, Christof;
- Ritgen, Matthias;
- Kreuzer, Karl-Anton;
- Chyla, Brenda;
- Paulson, Joseph N.;
- Pallasch, Christian P.;
- Frenzel, Lukas P.;
- Peifer, Martin;
- Eichhorst, Barbara;
- Stilgenbauer, Stephan
Publication type:
Article
Comprehensive Analysis of Disease-Related Genes in Chronic Lymphocytic Leukemia by Multiplex PCR-Based Next Generation Sequencing.
Published in:
PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0129544
By:
- Vollbrecht, Claudia;
- Mairinger, Fabian Dominik;
- Koitzsch, Ulrike;
- Peifer, Martin;
- Koenig, Katharina;
- Heukamp, Lukas Carl;
- Crispatzu, Giuliano;
- Wilden, Laura;
- Kreuzer, Karl-Anton;
- Hallek, Michael;
- Odenthal, Margarete;
- Herling, Carmen Diana;
- Buettner, Reinhard
Publication type:
Article
Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression.
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0125745
By:
- Boucas, Jorge;
- Fritz, Christian;
- Schmitt, Anna;
- Riabinska, Arina;
- Thelen, Lisa;
- Peifer, Martin;
- Leeser, Uschi;
- Nuernberg, Peter;
- Altmueller, Janine;
- Gaestel, Matthias;
- Dieterich, Christoph;
- Reinhardt, H. Christian
Publication type:
Article
Benchmarking of Mutation Diagnostics in Clinical Lung Cancer Specimens.
Published in:
PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019601
By:
- Querings, Silvia;
- Altmüller, Janine;
- Ansén, Sascha;
- Zander, Thomas;
- Seidel, Danila;
- Gabler, Franziska;
- Peifer, Martin;
- Markert, Eva;
- Stemshorn, Kathryn;
- Timmermann, Bernd;
- Saal, Beate;
- Klose, Stefan;
- Ernestus, Karen;
- Scheffler, Matthias;
- Engel-Riedel, Walburga;
- Stoelben, Erich;
- Brambilla, Elisabeth;
- Wolf, Jürgen;
- Nürnberg, Peter;
- Thomas, Roman K.
Publication type:
Article
Analysis of Compound Synergy in High-Throughput Cellular Screens by Population-Based Lifetime Modeling.
Published in:
PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008919
By:
- Peifer, Martin;
- Weiss, Jonathan;
- Sos, Martin L.;
- Koker, Mirjam;
- Heynck, Stefanie;
- Netzer, Christian;
- Fischer, Stefanie;
- Rode, Haridas;
- Rauh, Daniel;
- Rahnenführer, Jörg;
- Thomas, Roman K.
Publication type:
Article
High Expression Levels of Total IGF-1R and Sensitivity of NSCLC Cells In Vitro to an Anti-IGF-1R Antibody (R1507).
Published in:
PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007273
By:
- Yixuan Gong;
- Evelyn Yao;
- Shen, Ronglai;
- Goel, Aviva;
- Arcila, Maria;
- Teruya-Feldstein, Julie;
- Zakowski, Maureen F.;
- Frankel, Stanley;
- Peifer, Martin;
- Thomas, Roman K.;
- Ladanyi, Marc;
- Pao, William
Publication type:
Article
Variant profiling of colorectal adenomas from three patients of two families with MSH3-related adenomatous polyposis.
Published in:
PLoS ONE, 2021, v. 16, n. 11, p. 1, doi. 10.1371/journal.pone.0259185
By:
- Perne, Claudia;
- Peters, Sophia;
- Cartolano, Maria;
- Horpaopan, Sukanya;
- Grimm, Christina;
- Altmüller, Janine;
- Sommer, Anna K.;
- Hillmer, Axel M.;
- Thiele, Holger;
- Odenthal, Margarete;
- Möslein, Gabriela;
- Adam, Ronja;
- Sivalingam, Sugirthan;
- Kirfel, Jutta;
- Schweiger, Michal R.;
- Peifer, Martin;
- Spier, Isabel;
- Aretz, Stefan
Publication type:
Article
COSINE: A web server for clonal and subclonal structure inference and evolution in cancer genomics.
Published in:
2022
By:
- Xi-Guo Yuan;
- Yuan Zhao;
- Yang Guo;
- Lin-Mei Ge;
- Wei Liu;
- Shi-Yu Wen;
- Qi Li;
- Zhang-Bo Wan;
- Pei-Na Zheng;
- Tao Guo;
- Zhi-Da Li;
- Peifer, Martin;
- Yu-Peng Cun
Publication type:
Letter to the Editor
Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids.
Published in:
Nature Communications, 2014, v. 5, n. 3, p. 3518, doi. 10.1038/ncomms4518
By:
- Fernandez-Cuesta, Lynnette;
- Peifer, Martin;
- Lu, Xin;
- Sun, Ruping;
- Ozretić, Luka;
- Seidel, Danila;
- Zander, Thomas;
- Leenders, Frauke;
- George, Julie;
- Müller, Christian;
- Dahmen, Ilona;
- Pinther, Berit;
- Bosco, Graziella;
- Konrad, Kathryn;
- Altmüller, Janine;
- Nürnberg, Peter;
- Achter, Viktor;
- Lang, Ulrich;
- Schneider, Peter M.;
- Bogus, Magdalena
Publication type:
Article
Identification of novel fusion genes in lung cancer using breakpoint assembly of transcriptome sequencing data.
Published in:
Genome Biology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s13059-014-0558-0
By:
- Fernandez-Cuesta, Lynnette;
- Ruping Sun;
- Menon, Roopika;
- George, Julie;
- Lorenz, Susanne;
- Meza-Zepeda, Leonardo A.;
- Peifer, Martin;
- Plenker, Dennis;
- Heuckmann, Johannes M.;
- Leenders, Frauke;
- Zander, Thomas;
- Dahmen, Ilona;
- Koker, Mirjam;
- Schöttle, Jakob;
- Ullrich, Roland T.;
- Altmüller, Janine;
- Becker, Christian;
- Nürnberg, Peter;
- Seidel, Henrik;
- Böhm, Diana
Publication type:
Article
Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group.
Published in:
2015
By:
- Vollbrecht, Claudia;
- Werner, Robert;
- Walter, Robert Fred Henry;
- Christoph, Daniel Christian;
- Heukamp, Lukas Carl;
- Peifer, Martin;
- Hirsch, Burkhard;
- Burbat, Lina;
- Mairinger, Thomas;
- Schmid, Kurt Werner;
- Wohlschlaeger, Jeremias;
- Mairinger, Fabian Dominik;
- Kurt Werner, Schmid
Publication type:
journal article
Transcription-Induced Mutational Strand Bias and Its Effect on Substitution Rates in Human Genes.
Published in:
Molecular Biology & Evolution, 2009, v. 26, n. 1, p. 131
By:
- Mugal, Carina F.;
- Von Grünberg, Hans-Hennig;
- Peifer, Martin
Publication type:
Article
CaMuS: simultaneous fitting and de novo imputation of cancer mutational signature.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75753-8
By:
- Cartolano, Maria;
- Abedpour, Nima;
- Achter, Viktor;
- Yang, Tsun-Po;
- Ackermann, Sandra;
- Fischer, Matthias;
- Peifer, Martin
Publication type:
Article
Targeted Expression of Mutated ALK Induces Neuroblastoma in Transgenic Mice.
Published in:
Science Translational Medicine, 2012, v. 4, n. 141, p. 1, doi. 10.1126/scitranslmed.3003967
By:
- Heukamp, Lukas C.;
- Thor, Theresa;
- Schramm, Alexander;
- De Preter, Katleen;
- Kumps, Candy;
- De Wilde, Bram;
- Odersky, Andrea;
- Peifer, Martin;
- Lindner, Sven;
- Spruessel, Annika;
- Pattyn, Filip;
- Mestdagh, Pieter;
- Menten, Björn;
- Kuhfittig-Kulle, Steffi;
- Künkele, Annette;
- König, Katharina;
- Meder, Lydia;
- Chatterjee, Sampurna;
- Ullrich, Roland T.;
- Schulte, Stefanie
Publication type:
Article
Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer.
Published in:
Science Translational Medicine, 2010, v. 2, n. 62, p. 1, doi. 10.1126/scitranslmed.3001451
By:
- Weiss, Jonathan;
- Sos, Martin L.;
- Seidel, Danila;
- Peifer, Martin;
- Zander, Thomas;
- Heuckmann, Johannes M.;
- Ullrich, Roland T.;
- Menon, Roopika;
- Maier, Sebastian;
- Soltermann, Alex;
- Moch, Holger;
- Wagener, Patrick;
- Fischer, Florian;
- Heynck, Stefanie;
- Koker, Mirjam;
- Schöttle, Jakob;
- Leenders, Frauke;
- Gabler, Franziska;
- Dabow, Ines;
- Querings, Silvia
Publication type:
Article
Genomic ALK alterations in primary and relapsed neuroblastoma.
Published in:
British Journal of Cancer, 2023, v. 128, n. 8, p. 1559, doi. 10.1038/s41416-023-02208-y
By:
- Rosswog, Carolina;
- Fassunke, Jana;
- Ernst, Angela;
- Schömig-Markiefka, Birgid;
- Merkelbach-Bruse, Sabine;
- Bartenhagen, Christoph;
- Cartolano, Maria;
- Ackermann, Sandra;
- Theissen, Jessica;
- Blattner-Johnson, Mirjam;
- Jones, Barbara;
- Schramm, Kathrin;
- Altmüller, Janine;
- Nürnberg, Peter;
- Ortmann, Monika;
- Berthold, Frank;
- Peifer, Martin;
- Büttner, Reinhard;
- Westermann, Frank;
- Schulte, Johannes H.
Publication type:
Article
Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.
Published in:
Genes, Chromosomes & Cancer, 2012, v. 51, n. 1, p. 54, doi. 10.1002/gcc.20930
By:
- Chmielecki, Juliann;
- Peifer, Martin;
- Viale, Agnes;
- Hutchinson, Katherine;
- Giltnane, Jennifer;
- Socci, Nicholas D.;
- Hollis, Clayton J.;
- Dean, Rebecca S.;
- Yenamandra, Ashwini;
- Jagasia, Madan;
- Kim, Annette S.;
- Davé, Utpal P.;
- Thomas, Roman K.;
- Pao, William
Publication type:
Article
Telomerase activation by genomic rearrangements in high-risk neuroblastoma.
Published in:
Nature, 2015, v. 526, n. 7575, p. 700, doi. 10.1038/nature14980
By:
- Peifer, Martin;
- Hertwig, Falk;
- Roels, Frederik;
- Dreidax, Daniel;
- Gartlgruber, Moritz;
- Menon, Roopika;
- Krämer, Andrea;
- Roncaioli, Justin L.;
- Sand, Frederik;
- Heuckmann, Johannes M.;
- Ikram, Fakhera;
- Schmidt, Rene;
- Ackermann, Sandra;
- Engesser, Anne;
- Kahlert, Yvonne;
- Vogel, Wenzel;
- Altmüller, Janine;
- Nürnberg, Peter;
- Thierry-Mieg, Jean;
- Thierry-Mieg, Danielle
Publication type:
Article
iRODS metadata management for a cancer genome analysis workflow.
Published in:
BMC Bioinformatics, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s12859-018-2576-5
By:
- Nieroda, Lech;
- Maas, Lukas;
- Thiebes, Scott;
- Lang, Ulrich;
- Sunyaev, Ali;
- Achter, Viktor;
- Peifer, Martin
Publication type:
Article
Copy-number analysis and inference of subclonal populations in cancer genomes using Sclust.
Published in:
Nature Protocols, 2018, v. 13, n. 6, p. 1488, doi. 10.1038/nprot.2018.033
By:
- Cun, Yupeng;
- Yang, Tsun-Po;
- Achter, Viktor;
- Lang, Ulrich;
- Peifer, Martin
Publication type:
Article
BISTABILITY AND SELF-OSCILLATIONS IN CELL CYCLE CONTROL.
Published in:
International Journal of Bifurcation & Chaos in Applied Sciences & Engineering, 2006, v. 16, n. 4, p. 1057, doi. 10.1142/S0218127406015313
By:
- Petrov, Valko;
- Peifer, Martin;
- Timmer, Jens
Publication type:
Article
CGARS: cancer genome analysis by rank sums.
Published in:
Bioinformatics, 2014, v. 30, n. 9, p. 1295, doi. 10.1093/bioinformatics/btu011
By:
- Lu, Xin;
- Thomas, Roman K.;
- Peifer, Martin
Publication type:
Article

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