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Subcutaneous Atezolizumab: A Jab Without a Benefit.
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- Clinical Pharmacology in Drug Development, 2022, v. 11, n. 1, p. 134, doi. 10.1002/cpdd.1061
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- Article
A Quantitative Pharmacology Model of Exosome-Mediated Drug Efflux and Perturbation-Induced Synergy.
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- Pharmaceutics, 2021, v. 13, n. 7, p. 997, doi. 10.3390/pharmaceutics13070997
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- Article
Tofacitinib to prevent anti-drug antibody formation against LMB-100 immunotoxin in patients with advanced mesothelin-expressing cancers.
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- Frontiers in Oncology, 2024, p. 01, doi. 10.3389/fonc.2024.1386190
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- Article
Cardiac toxicity in a pilot study of duvelisib and ibrutinib combination therapy for chronic lymphocytic leukaemia.
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- British Journal of Haematology, 2023, v. 200, n. 2, p. 261, doi. 10.1111/bjh.18558
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- Article
Checkpoint inhibitor immunotherapy during pregnancy for relapsed–refractory Hodgkin lymphoma.
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- American Journal of Hematology, 2022, v. 97, n. 6, p. 833, doi. 10.1002/ajh.26527
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- Article
Local and Systemic Antitumor Effects of Photo‐activatable Paclitaxel Prodrug on Rat Breast Tumor Models.
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- Photochemistry & Photobiology, 2020, v. 96, n. 3, p. 668, doi. 10.1111/php.13202
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- Article
Opportunities for using in silico‐based extended dosing regimens for monoclonal antibody immune checkpoint inhibitors.
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- British Journal of Clinical Pharmacology, 2020, v. 86, n. 9, p. 1769, doi. 10.1111/bcp.14369
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- Article
Preclinical Evaluation of the FGFR-Family Inhibitor Futibatinib for Pediatric Rhabdomyosarcoma.
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- Cancers, 2023, v. 15, n. 16, p. 4034, doi. 10.3390/cancers15164034
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- Article
Targeting Pancreatic Cancer Cells and Stellate Cells Using Designer Nanotherapeutics in vitro.
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- International Journal of Nanomedicine, 2020, v. 15, p. 991, doi. 10.2147/IJN.S234112
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- Article
Systemic immune changes accompany combination treatment with immunotoxin LMB‐100 and nab‐paclitaxel.
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- Cancer Medicine, 2023, v. 12, n. 4, p. 4236, doi. 10.1002/cam4.5290
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- Article
HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer.
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- 2018
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- journal article
Alcohol and Aldehyde Dehydrogenases Contribute to Sex-Related Differences in Clearance of Zolpidem in Rats.
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- Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00260
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- Article
A Phase II Study of Sorafenib Combined With Cetuximab in EGFR-Expressing, KRAS-Mutated Metastatic Colorectal Cancer.
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- Clinical Colorectal Cancer, 2015, v. 14, n. 3, p. 154, doi. 10.1016/j.clcc.2015.02.007
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- Article
Dose Optimization of Pembrolizumab: Less May Be More.
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- Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 5, p. 993, doi. 10.1002/cpt.2490
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- Article
Pulmonary tumor thrombotic microangiopathy and pulmonary veno-occlusive disease in a woman with cervical cancer treated with cediranib and durvalumab.
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- 2018
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- Publication type:
- journal article
Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors.
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- Cancer Chemotherapy & Pharmacology, 2020, v. 86, n. 4, p. 475, doi. 10.1007/s00280-020-04134-9
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- Article
Cerebrospinal fluid penetration of the colony-stimulating factor-1 receptor (CSF-1R) inhibitor, pexidartinib.
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- 2020
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- journal article
Characterizing the pharmacokinetics of panobinostat in a non-human primate model for the treatment of diffuse intrinsic pontine glioma.
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- 2020
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- journal article
A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer.
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- 2019
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- journal article
A population pharmacokinetic/toxicity model for the reduction of platelets during a 48-h continuous intravenous infusion of the histone deacetylase inhibitor belinostat.
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- 2018
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- journal article
A phase I/II trial and pharmacokinetic study of mithramycin in children and adults with refractory Ewing sarcoma and EWS-FLI1 fusion transcript.
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- 2017
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- journal article
Carfilzomib and lenalidomide response related to VEGF and VEGFR2 germline polymorphisms.
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- 2017
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- journal article
Population pharmacokinetic analyses of the effect of carboplatin pretreatment on olaparib in recurrent or refractory women's cancers.
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- 2017
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- journal article
Pharmacokinetics of lenalidomide during high cut-off dialysis in a patient with multiple myeloma and renal failure.
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- 2017
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- Publication type:
- journal article
Cabozantinib plus docetaxel and prednisone in metastatic castration‐resistant prostate cancer.
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- BJU International, 2021, v. 127, n. 4, p. 435, doi. 10.1111/bju.15227
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- Article
Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors.
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- Cell Death & Disease, 2022, v. 13, n. 4, p. 1, doi. 10.1038/s41419-022-04868-9
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- Article
Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.
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- PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0152007
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- Article
Effects of UGT1A1 genotype on the pharmacokinetics, pharmacodynamics, and toxicities of belinostat administered by 48-hour continuous infusion in patients with cancer.
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- Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 461, doi. 10.1002/jcph.625
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- Article
UGT1A1 genotype-dependent dose adjustment of belinostat in patients with advanced cancers using population pharmacokinetic modeling and simulation.
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- Journal of Clinical Pharmacology, 2016, v. 56, n. 4, p. 450, doi. 10.1002/jcph.627
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- Article
Effectiveness of clopidogrel dose escalation to normalize active metabolite exposure and antiplatelet effects in CYP2C19 poor metabolizers.
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- Journal of Clinical Pharmacology, 2014, v. 54, n. 8, p. 865, doi. 10.1002/jcph.293
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- Article
Interventional pharmacoeconomics for immune checkpoint inhibitors through alternative dosing strategies.
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- British Journal of Cancer, 2023, v. 129, n. 9, p. 1389, doi. 10.1038/s41416-023-02367-y
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- Article
Phase 1 study of sorafenib and irinotecan in pediatric patients with relapsed or refractory solid tumors.
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- Pediatric Blood & Cancer, 2021, v. 68, n. 11, p. 1, doi. 10.1002/pbc.29282
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- Article
Evaluation of entinostat alone and in combination with standard-of-care cytotoxic agents against rhabdomyosarcoma xenograft models.
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- 2019
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- journal article
Alemtuzumab clearance, lymphocyte count, and T‐cell chimerism after hematopoietic stem cell transplant in sickle cell disease.
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- Pharmacotherapy, 2022, v. 42, n. 1, p. 14, doi. 10.1002/phar.2641
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- Article
Reactive astrocytic S1P3 signaling modulates the blood–tumor barrier in brain metastases.
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- Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05030-w
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- Article
In Silico Re‐Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure–Response Simulation.
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- Journal of Clinical Pharmacology, 2023, v. 63, n. 6, p. 672, doi. 10.1002/jcph.2203
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- Article
Pharmacokinetic Simulation Analysis of Less Frequent Nivolumab and Pembrolizumab Dosing: Pharmacoeconomic Rationale for Dose Deescalation.
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- Journal of Clinical Pharmacology, 2022, v. 62, n. 4, p. 532, doi. 10.1002/jcph.1984
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- Article
Pharmacodynamic markers and clinical results from the phase 2 study of the SMAC mimetic birinapant in women with relapsed platinum-resistant or -refractory epithelial ovarian cancer.
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- 2016
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- Publication type:
- journal article
A phase I trial of lenalidomide and radiotherapy in children with diffuse intrinsic pontine gliomas or high-grade gliomas.
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- Journal of Neuro-Oncology, 2020, v. 149, n. 3, p. 437, doi. 10.1007/s11060-020-03627-0
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- Article
Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single‐Dose Administration Under Fasting Conditions in Prostate Cancer.
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- Oncologist, 2021, v. 26, n. 9, p. 729, doi. 10.1002/onco.13919
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- Article
First‐in‐Human Phase I Study of Envafolimab, a Novel Subcutaneous Single‐Domain Anti‐PD‐L1 Antibody, in Patients with Advanced Solid Tumors.
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- Oncologist, 2021, v. 26, n. 9, p. e1514, doi. 10.1002/onco.13817
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- Article
A Phase Ib Study of Sorafenib (BAY 43-9006) in Patients with Kaposi Sarcoma.
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- Oncologist, 2017, v. 22, n. 5, p. 505, doi. 10.1634/theoncologist.2016-0486
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- Article
Distinct uptake and elimination profiles for trastuzumab, human IgG, and biocytin-TMR in experimental HER2+ brain metastases of breast cancer.
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- Neuro-Oncology, 2024, v. 26, n. 6, p. 1067, doi. 10.1093/neuonc/noae025
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- Article
Phase I trial of panobinostat in children with diffuse intrinsic pontine glioma: A report from the Pediatric Brain Tumor Consortium (PBTC-047).
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- Neuro-Oncology, 2023, v. 25, n. 12, p. 2262, doi. 10.1093/neuonc/noad141
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- Article
Inhibition of p38α MAPK restores neuronal p38γ MAPK and ameliorates synaptic degeneration in a mouse model of DLB/PD.
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- Science Translational Medicine, 2023, v. 15, n. 695, p. 1, doi. 10.1126/scitranslmed.abq6089
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- Article
Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics.
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- Science Translational Medicine, 2021, v. 13, n. 625, p. 1, doi. 10.1126/scitranslmed.abd8077
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- Article
Synergistic targeted inhibition of MEK and dual PI3K/ mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma.
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- Pigment Cell & Melanoma Research, 2016, v. 29, n. 6, p. 643, doi. 10.1111/pcmr.12512
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- Article
Phase 1 study of the immunotoxin LMB‐100 in patients with mesothelioma and other solid tumors expressing mesothelin.
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- Cancer (0008543X), 2020, v. 126, n. 22, p. 4936, doi. 10.1002/cncr.33145
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- Article