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Mutation analysis of PIK3CA and PIK3CB in esophageal cancer and Barrett's esophagus.
- Published in:
- International Journal of Cancer, 2006, v. 118, n. 10, p. 2644, doi. 10.1002/ijc.21706
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- Publication type:
- Article
Spatial analysis with SPIAT and spaSim to characterize and simulate tissue microenvironments.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37822-0
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- Publication type:
- Article
UBF levels determine the number of active ribosomal RNA genes in mammals.
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- Journal of Cell Biology, 2008, v. 183, n. 7, p. 1259, doi. 10.1083/jcb.200805146
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- Publication type:
- Article
Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70<sup>s6k</sup>.
- Published in:
- EMBO Journal, 1997, v. 16, n. 12, p. 3693, doi. 10.1093/emboj/16.12.3693
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- Publication type:
- Article
The Potential of Targeting Ribosome Biogenesis in High-Grade Serous Ovarian Cancer.
- Published in:
- International Journal of Molecular Sciences, 2017, v. 18, n. 1, p. 210, doi. 10.3390/ijms18010210
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- Publication type:
- Article
Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation.
- Published in:
- Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0284-y
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- Publication type:
- Article
Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy.
- Published in:
- Signal Transduction & Targeted Therapy, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41392-021-00728-8
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- Publication type:
- Article
Relative Expression Levels Rather Than Specific Activity Plays the Major Role in Determining In Vivo AKT Isoform Substrate Specificity.
- Published in:
- Enzyme Research, 2011, p. 1, doi. 10.4061/2011/720985
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- Publication type:
- Article
The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer.
- Published in:
- 2021
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- Publication type:
- journal article
Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis.
- Published in:
- PLoS Genetics, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.pgen.1003279
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- Publication type:
- Article
Drosophila Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone.
- Published in:
- PLoS Genetics, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.pgen.1002408
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- Publication type:
- Article
Methylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinoma.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05564-z
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- Publication type:
- Article
Therapeutic Approaches Targeting MYC-Driven Prostate Cancer.
- Published in:
- Genes, 2017, v. 8, n. 2, p. 71, doi. 10.3390/genes8020071
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- Publication type:
- Article
Autophosphorylation of serine 608 in the p85 regulatory subunit of wild type or cancer-associated mutants of phosphoinositide 3-kinase does not affect its lipid kinase activity.
- Published in:
- BMC Biochemistry, 2012, v. 13, n. 1, p. 30, doi. 10.1186/1471-2091-13-30
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- Publication type:
- Article
Dual posttranscriptional targets of retinoic acid-induced gene expression.
- Published in:
- Journal of Cellular Biochemistry, 1999, v. 72, n. 3, p. 411, doi. 10.1002/(SICI)1097-4644(19990301)72:3<411::AID-JCB10>3.0.CO;2-X
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- Publication type:
- Article
Signaling to the ribosome in cancer-It is more than just mTORC1.
- Published in:
- IUBMB Life, 2011, v. 63, n. 2, p. 79, doi. 10.1002/iub.428
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- Publication type:
- Article
Signaling to the ribosome in cancer-It is more than just mTORC1.
- Published in:
- 2011
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- Publication type:
- Other
Widespread FRA1-Dependent Control of Mesenchymal Transdifferentiation Programs in Colorectal Cancer Cells.
- Published in:
- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0088950
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- Publication type:
- Article
Deregulation of MYCN, LIN28B and LET7 in a Molecular Subtype of Aggressive High-Grade Serous Ovarian Cancers.
- Published in:
- PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018064
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- Publication type:
- Article
Dysregulation of the basal RNA polymerase transcription apparatus in cancer.
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- 2013
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- Publication type:
- journal article
Dysregulation of the basal RNA polymerase transcription apparatus in cancer.
- Published in:
- Nature Reviews Cancer, 2013, v. 13, n. 5, p. 299, doi. 10.1038/nrc3496
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- Publication type:
- Article
Loss of CDKN2A expression is a frequent event in primary invasive melanoma and correlates with sensitivity to the CDK4/6 inhibitor PD0332991 in melanoma cell lines.
- Published in:
- Pigment Cell & Melanoma Research, 2014, v. 27, n. 4, p. 590, doi. 10.1111/pcmr.12228
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- Publication type:
- Article
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation.
- Published in:
- EMBO Journal, 2004, v. 23, n. 16, p. 3325, doi. 10.1038/sj.emboj.7600335
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- Publication type:
- Article
An activating Pik3ca mutation coupled with Pten loss is sufficient to initiate ovarian tumorigenesis in mice.
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- Journal of Clinical Investigation, 2012, v. 122, n. 2, p. 553, doi. 10.1172/JCI59309
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- Publication type:
- Article
Cystathionine-β-synthase is essential for AKT-induced senescence and suppresses the development of gastric cancers with PI3K/AKT activation.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.71929
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- Publication type:
- Article
Cystathionine β-Synthase in Physiology and Cancer.
- Published in:
- BioMed Research International, 2018, v. 2018, p. 1, doi. 10.1155/2018/3205125
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- Publication type:
- Article
The transcription cofactor c-JUN mediates phenotype switching and BRAF inhibitor resistance in melanoma.
- Published in:
- Science Signaling, 2015, v. 8, n. 390, p. 1, doi. 10.1126/scisignal.aab1111
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- Publication type:
- Article
AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer.
- Published in:
- Science Signaling, 2011, v. 4, n. 188, p. 1, doi. 10.1126/scisignal.2001754
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- Publication type:
- Article
Combining High-Content Imaging and Phenotypic Classification Analysis of Senescence-Associated Beta-Galactosidase Staining to Identify Regulators of Oncogene-Induced Senescence.
- Published in:
- Assay & Drug Development Technologies, 2016, v. 14, n. 7, p. 416, doi. 10.1089/adt.2016.739
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- Publication type:
- Article
AKT-independent PI3-K signaling in cancer -emerging role for SGK3.
- Published in:
- Cancer Management & Research, 2013, v. 5, p. 281, doi. 10.2147/CMAR.S35178
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- Publication type:
- Article
Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance.
- Published in:
- International Journal of Cancer, 2018, v. 142, n. 10, p. 2139, doi. 10.1002/ijc.31220
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- Publication type:
- Article
Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70<sup>s6k</sup>/p85<sup>s6k</sup>: implications for the analysis of S6K signalling
- Published in:
- FEBS Letters, 2002, v. 519, n. 1-3, p. 135, doi. 10.1016/S0014-5793(02)02738-2
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- Publication type:
- Article
How the evolution of multicellularity set the stage for cancer.
- Published in:
- 2018
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- Publication type:
- journal article
Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.
- Published in:
- EMBO Journal, 2020, v. 39, n. 21, p. 1, doi. 10.15252/embj.2020105111
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- Publication type:
- Article
AKT signalling is required for ribosomal RNA synthesis and progression of Eμ- Myc B-cell lymphoma in vivo.
- Published in:
- FEBS Journal, 2013, v. 280, n. 21, p. 5307, doi. 10.1111/febs.12135
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- Publication type:
- Article