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Phase 1 study to evaluate the effect of the MEK inhibitor trametinib on cardiac repolarization in patients with solid tumours.
Published in:
2016
By:
- Patnaik, Amita;
- Tolcher, Anthony;
- Papadopoulos, Kyriakos;
- Beeram, Murali;
- Rasco, Drew;
- Werner, Theresa;
- Bauman, John;
- Scheuber, Anita;
- Cox, Donna;
- Patel, Bela;
- Zhou, YanYan;
- Hamid, Mohammed;
- Schramek, Daniel;
- Sharma, Sunil;
- Papadopoulos, Kyriakos P;
- Werner, Theresa L;
- Bauman, John W;
- Cox, Donna S;
- Patel, Bela R
Publication type:
journal article
Utility of concentration-effect modeling and simulation in a thorough QT study of losmapimod.
Published in:
Journal of Clinical Pharmacology, 2015, v. 55, n. 6, p. 661, doi. 10.1002/jcph.465
By:
- Barbour, April M.;
- Magee, Mindy;
- Shaddinger, Bonnie;
- Arya, Niki;
- Tombs, Lee;
- Tao, Wenli;
- Patel, Bela R.;
- Fossler, Michael J.;
- Glaser, Ruchira
Publication type:
Article
Tafenoquine at therapeutic concentrations does not prolong fridericia-corrected QT interval in healthy subjects.
Published in:
Journal of Clinical Pharmacology, 2014, v. 54, n. 9, p. 995, doi. 10.1002/jcph.302
By:
- Green, Justin A.;
- Patel, Apurva K.;
- Patel, Bela R.;
- Hussaini, Azra;
- Harrell, Emma J.;
- McDonald, Mirna J.;
- Carter, Nick;
- Mohamed, Khadeeja;
- Duparc, Stephan;
- Miller, Ann K.
Publication type:
Article
Population pharmacokinetics of ofatumumab in patients with chronic lymphocytic leukemia, follicular lymphoma, and rheumatoid arthritis.
Published in:
Journal of Clinical Pharmacology, 2014, v. 54, n. 7, p. 818, doi. 10.1002/jcph.268
By:
- Struemper, Herbert;
- Sale, Mark;
- Patel, Bela R.;
- Østergaard, Mikkel;
- Österborg, Anders;
- Wierda, William G.;
- Hagenbeek, Anton;
- Coiffier, Bertrand;
- Jewell, Roxanne C.
Publication type:
Article
Pharmacokinetic and Pharmacodynamic Basis for Effective Argatroban Dosing in Pediatrics.
Published in:
Journal of Clinical Pharmacology, 2011, v. 51, n. 1, p. 19, doi. 10.1177/0091270010365550
By:
- Madabushi, Rajanikanth;
- Cox, Donna S.;
- Hossain, Mohammad;
- Boyle, Duane A.;
- Patel, Bela R.;
- Young, Guy;
- Choi, Young-Moon;
- Gobburu, Jogarao V. S.
Publication type:
Article

Found: 5

Phase 1 study to evaluate the effect of the MEK inhibitor trametinib on cardiac repolarization in patients with solid tumours.

Utility of concentration-effect modeling and simulation in a thorough QT study of losmapimod.

Tafenoquine at therapeutic concentrations does not prolong fridericia-corrected QT interval in healthy subjects.

Population pharmacokinetics of ofatumumab in patients with chronic lymphocytic leukemia, follicular lymphoma, and rheumatoid arthritis.

Pharmacokinetic and Pharmacodynamic Basis for Effective Argatroban Dosing in Pediatrics.