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Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37290-6
By:
- Mäkelä, Anna R.;
- Uğurlu, Hasan;
- Hannula, Liina;
- Kant, Ravi;
- Salminen, Petja;
- Fagerlund, Riku;
- Mäki, Sanna;
- Haveri, Anu;
- Strandin, Tomas;
- Kareinen, Lauri;
- Hepojoki, Jussi;
- Kuivanen, Suvi;
- Levanov, Lev;
- Pasternack, Arja;
- Naves, Rauno A.;
- Ritvos, Olli;
- Österlund, Pamela;
- Sironen, Tarja;
- Vapalahti, Olli;
- Kipar, Anja
Publication type:
Article
Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres.
Published in:
eLife, 2016, p. 1, doi. 10.7554/eLife.16940
By:
- Omairi, Saleh;
- Matsakas, Antonios;
- Degens, Hans;
- Kretz, Oliver;
- Hansson, Kenth-Arne;
- Solbrå, Andreas Våvang;
- Bruusgaard, Jo C.;
- Joch, Barbara;
- Sartori, Roberta;
- Giallourou, Natasa;
- Mitchell, Robert;
- Collins-Hooper, Henry;
- Foster, Keith;
- Pasternack, Arja;
- Ritvos, Olli;
- Sandri, Marco;
- Narkar, Vihang;
- Swann, Jonathan R.;
- Huber, Tobias B.;
- Patel, Ketan
Publication type:
Article
Coronavirus spike protein-specific antibodies indicate frequent infections and reinfections in infancy and among BNT162b2-vaccinated healthcare workers.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35471-3
By:
- Kolehmainen, Pekka;
- Huttunen, Moona;
- Iakubovskaia, Alina;
- Maljanen, Sari;
- Tauriainen, Sisko;
- Yatkin, Emrah;
- Pasternack, Arja;
- Naves, Rauno;
- Toivonen, Laura;
- Tähtinen, Paula A.;
- Ivaska, Lauri;
- Lempainen, Johanna;
- Peltola, Ville;
- Waris, Matti;
- Kakkola, Laura;
- Ritvos, Olli;
- Julkunen, Ilkka
Publication type:
Article
Comparative analysis of COVID-19 vaccine responses and third booster dose-induced neutralizing antibodies against Delta and Omicron variants.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30162-5
By:
- Belik, Milja;
- Jalkanen, Pinja;
- Lundberg, Rickard;
- Reinholm, Arttu;
- Laine, Larissa;
- Väisänen, Elina;
- Skön, Marika;
- Tähtinen, Paula A.;
- Ivaska, Lauri;
- Pakkanen, Sari H.;
- Häkkinen, Hanni K.;
- Ortamo, Eeva;
- Pasternack, Arja;
- Ritvos, Mikael A.;
- Naves, Rauno A.;
- Miettinen, Simo;
- Sironen, Tarja;
- Vapalahti, Olli;
- Ritvos, Olli;
- Österlund, Pamela
Publication type:
Article
COVID-19 mRNA vaccine induced antibody responses against three SARS-CoV-2 variants.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24285-4
By:
- Jalkanen, Pinja;
- Kolehmainen, Pekka;
- Häkkinen, Hanni K.;
- Huttunen, Moona;
- Tähtinen, Paula A.;
- Lundberg, Rickard;
- Maljanen, Sari;
- Reinholm, Arttu;
- Tauriainen, Sisko;
- Pakkanen, Sari H.;
- Levonen, Iris;
- Nousiainen, Arttu;
- Miller, Taru;
- Välimaa, Hanna;
- Ivaska, Lauri;
- Pasternack, Arja;
- Naves, Rauno;
- Ritvos, Olli;
- Österlund, Pamela;
- Kuivanen, Suvi
Publication type:
Article
Upregulation of activin-B and follistatin in pulmonary fibrosis -- a translational study using human biopsies and a specific inhibitor in mouse fibrosis models.
Published in:
BMC Pulmonary Medicine, 2014, v. 14, p. 1, doi. 10.1186/1471-2466-14-170
By:
- Myllärniemi, Marjukka;
- Tikkanen, Jussi;
- Hulmi, Juha J.;
- Pasternack, Arja;
- Sutinen, Eva;
- Rönty, Mikko;
- Leppäranta, Outi;
- Hongqiang Ma;
- Ritvos, Olli;
- Koli, Katri
Publication type:
Article
Upregulation of activin-B and follistatin in pulmonary fibrosis - a translational study using human biopsies and a specific inhibitor in mouse fibrosis models.
Published in:
2014
By:
- Myllärniemi, Marjukka;
- Tikkanen, Jussi;
- Hulmi, Juha J;
- Pasternack, Arja;
- Sutinen, Eva;
- Rönty, Mikko;
- Leppäranta, Outi;
- Ma, Hongqiang;
- Ritvos, Olli;
- Koli, Katri
Publication type:
journal article
Diminution in sperm quantity and quality in mouse models of Duchenne Muscular Dystrophy induced by a myostatin-based muscle growth-promoting intervention.
Published in:
European Journal of Translational Myology, 2020, v. 30, n. 2, p. 276, doi. 10.4081/ejtm.2020.8904
By:
- Vaughan, Danielle;
- Kretz, Oliver;
- Alqallaf, Ali;
- Mitchell, Robert;
- der Heide, Jennie L;
- Vaiyapuri, Sakthivel;
- Matsakas, Antonios;
- Pasternack, Arja;
- Collins-Hooper, Henry;
- Ritvos, Olli;
- Ballesteros, Randy;
- Huber, Tobias B.;
- Amthor, Helge;
- Mukherjee, Abir;
- Patel, Ketan
Publication type:
Article
Inhibition of Activin/Myostatin signalling induces skeletal muscle hypertrophy but impairs mouse testicular development.
Published in:
European Journal of Translational Myology, 2020, v. 30, n. 1, p. 1, doi. 10.4081/ejtm.2019.8737
By:
- Vaughan, Danielle;
- Ritvos, Olli;
- Mitchel, Robert;
- Kretz, Oliver;
- Lalowski, Maciej;
- Amthor, Helge;
- Chambers, David;
- Matsakas, Antonios;
- Pasternack, Arja;
- Collins-Hooper, Henry;
- Ballesteros, Randy;
- Huber, Tobias B.;
- Denecke, Bernd;
- Widera, Darius;
- Mukherjee, Abir;
- Patel, Ketan
Publication type:
Article
Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice.
Published in:
Amino Acids, 2017, v. 49, n. 3, p. 529, doi. 10.1007/s00726-016-2306-0
By:
- Kalliokoski, Suvi;
- Piqueras, Victoria;
- Frías, Rafael;
- Sulic, Ana-Marija;
- Määttä, Juha;
- Kähkönen, Niklas;
- Viiri, Keijo;
- Huhtala, Heini;
- Pasternack, Arja;
- Laurila, Kaija;
- Sblattero, Daniele;
- Korponay-Szabó, Ilma;
- Mäki, Markku;
- Caja, Sergio;
- Kaukinen, Katri;
- Lindfors, Katri
Publication type:
Article
Differentiation of Murine C2C12 Myoblasts Strongly Reduces the Effects of Myostatin on Intracellular Signaling.
Published in:
Biomolecules (2218-273X), 2020, v. 10, n. 5, p. 695, doi. 10.3390/biom10050695
By:
- Lautaoja, Juulia H.;
- Pekkala, Satu;
- Pasternack, Arja;
- Laitinen, Mika;
- Ritvos, Olli;
- Hulmi, Juha J.
Publication type:
Article
Activin inhibition limits early innate immune response in rat kidney allografts-a pilot study.
Published in:
Transplant International, 2017, v. 30, n. 1, p. 96, doi. 10.1111/tri.12876
By:
- Palin, Niina K.;
- Savikko, Johanna;
- Pasternack, Arja;
- Rintala, Jukka M.;
- Kalra, Bhanu;
- Mistry, Shivani;
- Kumar, Ajay;
- Roth, Marie-Paule;
- Helin, Heikki;
- Ritvos, Olli
Publication type:
Article
Muscle follistatin gene delivery increases muscle protein synthesis independent of periodical physical inactivity and fasting.
Published in:
FASEB Journal, 2021, v. 35, n. 3, p. 1, doi. 10.1096/fj.202002008R
By:
- Nissinen, Tuuli A.;
- Hentilä, Jaakko;
- Fachada, Vasco;
- Lautaoja, Juulia H.;
- Pasternack, Arja;
- Ritvos, Olli;
- Kivelä, Riikka;
- Hulmi, Juha J.
Publication type:
Article
Systemic blockade of ACVR2B ligands attenuates muscle wasting in ischemic heart failure without compromising cardiac function.
Published in:
FASEB Journal, 2020, v. 34, n. 8, p. 9911, doi. 10.1096/fj.201903074RR
By:
- Szabó, Zoltán;
- Vainio, Laura;
- Lin, Ruizhu;
- Swan, Julia;
- Hulmi, Juha J.;
- Rahtu‐Korpela, Lea;
- Serpi, Raisa;
- Laitinen, Mika;
- Pasternack, Arja;
- Ritvos, Olli;
- Kerkelä, Risto;
- Magga, Johanna
Publication type:
Article
Pro-cachectic factors link experimental and human chronic kidney disease to skeletal muscle wasting programs.
Published in:
2021
By:
- Solagna, Francesca;
- Tezze, Caterina;
- Lindenmeyer, Maja T.;
- Shun Lu;
- Guochao Wu;
- Shuya Liu;
- Yu Zhao;
- Mitchell, Robert;
- Meyer, Charlotte;
- Omairi, Saleh;
- Kilic, Temel;
- Paolini, Andrea;
- Ritvos, Olli;
- Pasternack, Arja;
- Matsakas, Antonios;
- Kylies, Dominik;
- zur Wiesch, Julian Schulze;
- Turner, Jan-Eric;
- Wanner, Nicola;
- Nair, Viji
Publication type:
journal article
Activin Receptor Ligand Blocking and Cancer Have Distinct Effects on Protein and Redox Homeostasis in Skeletal Muscle and Liver.
Published in:
Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2018.01917
By:
- Hentilä, Jaakko;
- Nissinen, Tuuli A.;
- Korkmaz, Ayhan;
- Lensu, Sanna;
- Silvennoinen, Mika;
- Pasternack, Arja;
- Ritvos, Olli;
- Atalay, Mustafa;
- Hulmi, Juha J.
Publication type:
Article
Functional characterization of ratρ<sub>2</sub> subunits expressed in HEK 293 cells.
Published in:
European Journal of Neuroscience, 2005, v. 21, n. 3, p. 692, doi. 10.1111/j.1460-9568.2005.03880.x
By:
- Alakuijala, Anniina;
- TalviOja, Katri;
- Pasternack, Arja;
- Pasternack, Michael
Publication type:
Article
Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of Duchenne muscular dystrophy.
Published in:
2017
By:
- Puolakkainen, Tero;
- Hongqian Ma;
- Kainulainen, Heikki;
- Pasternack, Arja;
- Rantalainen, Timo;
- Ritvos, Olli;
- Heikinheimo, Kristiina;
- Hulmi, Juha J.;
- Kiviranta, Riku;
- Ma, Hongqian
Publication type:
journal article
Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2019, v. 10, n. 3, p. 662, doi. 10.1002/jcsm.12404
By:
- Alyodawi, Khalid;
- Vermeij, Wilbert P.;
- Omairi, Saleh;
- Kretz, Oliver;
- Hopkinson, Mark;
- Solagna, Francesca;
- Joch, Barbara;
- Brandt, Renata M.C.;
- Barnhoorn, Sander;
- Vliet, Nicole;
- Ridwan, Yanto;
- Essers, Jeroen;
- Mitchell, Robert;
- Morash, Taryn;
- Pasternack, Arja;
- Ritvos, Olli;
- Matsakas, Antonios;
- Collins‐Hooper, Henry;
- Huber, Tobias B.;
- Hoeijmakers, Jan H.J.
Publication type:
Article
A Combination of N and S Antigens With IgA and IgG Measurement Strengthens the Accuracy of SARS-CoV-2 Serodiagnostics.
Published in:
2021
By:
- Jalkanen, Pinja;
- Pasternack, Arja;
- Maljanen, Sari;
- Melén, Krister;
- Kolehmainen, Pekka;
- Huttunen, Moona;
- Lundberg, Rickard;
- Tripathi, Lav;
- Khan, Hira;
- Ritvos, Mikael A;
- Naves, Rauno;
- Haveri, Anu;
- Österlund, Pamela;
- Kuivanen, Suvi;
- Jääskeläinen, Anne J;
- Kurkela, Satu;
- Lappalainen, Maija;
- Rantasärkkä, Kaisa;
- Vuorinen, Tytti;
- Hytönen, Jukka
Publication type:
journal article
The Activin/Follistatin Axis Is Severely Deregulated in COVID-19 and Independently Associated With In-Hospital Mortality.
Published in:
2021
By:
- Synolaki, Evgenia;
- Papadopoulos, Vasileios;
- Divolis, Georgios;
- Tsahouridou, Olga;
- Gavriilidis, Efstratios;
- Loli, Georgia;
- Gavriil, Ariana;
- Tsigalou, Christina;
- Tziolos, Nikolaos R;
- Sertaridou, Eleni;
- Kalra, Bhanu;
- Kumar, Ajay;
- Rafailidis, Petros;
- Pasternack, Arja;
- Boumpas, Dimitrios T;
- Germanidis, Georgios;
- Ritvos, Olli;
- Metallidis, Simeon;
- Skendros, Panagiotis;
- Sideras, Paschalis
Publication type:
journal article
Characterization of the functional role of the N -glycans in the AMPA receptor ligand-binding domain.
Published in:
Journal of Neurochemistry, 2003, v. 84, n. 5, p. 1184, doi. 10.1046/j.1471-4159.2003.01611.x
By:
- Pasternack, Arja;
- Coleman, Sarah K.;
- Féthière, James;
- Madden, Dean R.;
- LeCaer, Jean-Pierre;
- Rossier, Jean;
- Pasternack, Michael;
- Keinänen, Kari
Publication type:
Article

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