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Systematic profiling of conditional degron tag technologies for target validation studies.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33246-4
By:
- Bondeson, Daniel P.;
- Mullin-Bernstein, Zachary;
- Oliver, Sydney;
- Skipper, Thomas A.;
- Atack, Thomas C.;
- Bick, Nolan;
- Ching, Meilani;
- Guirguis, Andrew A.;
- Kwon, Jason;
- Langan, Carly;
- Millson, Dylan;
- Paolella, Brenton R.;
- Tran, Kevin;
- Wie, Sarah J.;
- Vazquez, Francisca;
- Tothova, Zuzana;
- Golub, Todd R.;
- Sellers, William R.;
- Ianari, Alessandra
Publication type:
Article
Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.23268
By:
- Paolella, Brenton R.;
- Gibson, William J.;
- Urbanski, Laura M.;
- Alberta, John A.;
- Zack, Travis I.;
- Bandopadhayay, Pratiti;
- Nichols, Caitlin A.;
- Agarwalla, Pankaj K.;
- Brown, Meredith S.;
- Lamothe, Rebecca;
- Yong Yu;
- Choi, Peter S.;
- Obeng, Esther A.;
- Heckl, Dirk;
- Guo Wei;
- Wang, Belinda;
- Tsherniak, Aviad;
- Vazquez, Francisca;
- Weir, Barbara A.;
- Root, David E.
Publication type:
Article
p53 Directly Represses Id2 to Inhibit the Proliferation of Neural Progenitor Cells.
Published in:
Stem Cells, 2011, v. 29, n. 7, p. 1090, doi. 10.1002/stem.660
By:
- Paolella, Brenton R.;
- Havrda, Matthew C.;
- Mantani, Akio;
- Wray, Christina M.;
- Zhang, Zhonghua;
- Israel, Mark A.
Publication type:
Article
Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11493-2
By:
- Reitman, Zachary J.;
- Paolella, Brenton R.;
- Bergthold, Guillaume;
- Pelton, Kristine;
- Becker, Sarah;
- Jones, Robert;
- Sinai, Claire E.;
- Malkin, Hayley;
- Huang, Ying;
- Grimmet, Leslie;
- Herbert, Zachary T.;
- Sun, Yu;
- Weatherbee, Jessica L.;
- Alberta, John A.;
- Daley, John F.;
- Rozenblatt-Rosen, Orit;
- Condurat, Alexandra L.;
- Qian, Kenin;
- Khadka, Prasidda;
- Segal, Rosalind A.
Publication type:
Article
Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10307-9
By:
- Bandopadhayay, Pratiti;
- Piccioni, Federica;
- O'Rourke, Ryan;
- Ho, Patricia;
- Gonzalez, Elizabeth M.;
- Buchan, Graham;
- Qian, Kenin;
- Gionet, Gabrielle;
- Girard, Emily;
- Coxon, Margo;
- Rees, Matthew G.;
- Brenan, Lisa;
- Dubois, Frank;
- Shapira, Ofer;
- Greenwald, Noah F.;
- Pages, Melanie;
- Balboni Iniguez, Amanda;
- Paolella, Brenton R.;
- Meng, Alice;
- Sinai, Claire
Publication type:
Article
Phosphorylation Regulates Id2 Degradation and Mediates the Proliferation of Neural Precursor Cells.
Published in:
Stem Cells, 2016, v. 34, n. 5, p. 1321, doi. 10.1002/stem.2291
By:
- Sullivan, Jaclyn M.;
- Havrda, Matthew C.;
- Zhang, Zhonghua;
- Israel, Mark A.;
- Kettenbach, Arminja N.;
- Gerber, Scott A.;
- Paolella, Brenton R.
Publication type:
Article
Id2 Is Required for Specification of Dopaminergic Neurons during Adult Olfactory Neurogenesis.
Published in:
Journal of Neuroscience, 2008, v. 28, n. 52, p. 14074, doi. 10.1523/JNEUROSCI.3188-08.2008
By:
- Havrda, Matthew C.;
- Harris, Brent T.;
- Mantani, Akio;
- Ward, Nora M.;
- Paolella, Brenton R.;
- Cuzon, Verginia C.;
- Yeh, Hermes H.;
- Israel, Mark A.
Publication type:
Article
Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.
Published in:
Neuro-Oncology, 2015, v. 17, n. 11, p. 1486, doi. 10.1093/neuonc/nov045
By:
- Bergthold, Guillaume;
- Bandopadhayay, Pratiti;
- Hoshida, Yujin;
- Ramkissoon, Shakti;
- Ramkissoon, Lori;
- Rich, Benjamin;
- Maire, Cecile L.;
- Paolella, Brenton R.;
- Schumacher, Steven E.;
- Tabak, Barbara;
- Ferrer-Luna, Ruben;
- Ozek, Memet;
- Sav, Aydin;
- Santagata, Sandro;
- Patrick Yung Wen;
- Goumnerova, Liliana C.;
- Ligon, Azra H.;
- Stiles, Charles;
- Segal, Rosalind;
- Golub, Todd
Publication type:
Article
Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal.
Published in:
Genome Biology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s13059-023-03020-w
By:
- Krill-Burger, J. Michael;
- Dempster, Joshua M.;
- Borah, Ashir A.;
- Paolella, Brenton R.;
- Root, David E.;
- Golub, Todd R.;
- Boehm, Jesse S.;
- Hahn, William C.;
- McFarland, James M.;
- Vazquez, Francisca;
- Tsherniak, Aviad
Publication type:
Article
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-17440-w
By:
- McFarland, James M.;
- Paolella, Brenton R.;
- Warren, Allison;
- Geiger-Schuller, Kathryn;
- Shibue, Tsukasa;
- Rothberg, Michael;
- Kuksenko, Olena;
- Colgan, William N.;
- Jones, Andrew;
- Chambers, Emily;
- Dionne, Danielle;
- Bender, Samantha;
- Wolpin, Brian M.;
- Ghandi, Mahmoud;
- Tirosh, Itay;
- Rozenblatt-Rosen, Orit;
- Roth, Jennifer A.;
- Golub, Todd R.;
- Regev, Aviv;
- Aguirre, Andrew J.
Publication type:
Article
Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16399-y
By:
- Nichols, Caitlin A.;
- Gibson, William J.;
- Brown, Meredith S.;
- Kosmicki, Jack A.;
- Busanovich, John P.;
- Wei, Hope;
- Urbanski, Laura M.;
- Curimjee, Naomi;
- Berger, Ashton C.;
- Gao, Galen F.;
- Cherniack, Andrew D.;
- Dhe-Paganon, Sirano;
- Paolella, Brenton R.;
- Beroukhim, Rameen
Publication type:
Article

Found: 11