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In vitro and in vivo dissolution of biocompatible S59 glass scaffolds.
Published in:
Journal of Materials Science: Materials in Medicine, 2024, v. 35, n. 1, p. 1, doi. 10.1007/s10856-024-06795-x
By:
- Aalto-Setälä, Laura;
- Uppstu, Peter;
- Björkenheim, Robert;
- Strömberg, Gustav;
- Lindfors, Nina C.;
- Pajarinen, Jukka;
- Hupa, Leena
Publication type:
Article
Evaluation of bone growth around bioactive glass S53P4 by scanning acoustic microscopy co-registered with optical interferometry and elemental analysis.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-33454-y
By:
- Holmström, Axi;
- Meriläinen, Antti;
- Hyvönen, Jere;
- Nolvi, Anton;
- Ylitalo, Tuomo;
- Steffen, Kari;
- Björkenheim, Robert;
- Strömberg, Gustav;
- Nieminen, Heikki J.;
- Kassamakov, Ivan;
- Pajarinen, Jukka;
- Hupa, Leena;
- Salmi, Ari;
- Hæggström, Edward;
- Lindfors, Nina C.
Publication type:
Article
Establishment of Green Fluorescent Protein and Firefly Luciferase Expressing Mouse Primary Macrophages for In Vivo Bioluminescence Imaging.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142736
By:
- Pajarinen, Jukka;
- Lin, Tzu-hua;
- Sato, Taishi;
- Loi, Florence;
- Yao, Zhenyu;
- Konttinen, Yrjö T.;
- Goodman, Stuart B.
Publication type:
Article
NFκB sensing IL‐4 secreting mesenchymal stem cells mitigate the proinflammatory response of macrophages exposed to polyethylene wear particles.
Published in:
Journal of Biomedical Materials Research, Part A, 2018, v. 106, n. 10, p. 2744, doi. 10.1002/jbm.a.36504
By:
- Lin, Tzuhua;
- Kohno, Yusuke;
- Huang, Jhih‐Fong;
- Romero‐Lopez, Monica;
- Pajarinen, Jukka;
- Maruyama, Masahiro;
- Nathan, Karthik;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
C CL2, CCL5, and IGF-1 participate in the immunomodulation of osteogenesis during M1/M2 transition in vitro.
Published in:
Journal of Biomedical Materials Research, Part A, 2017, v. 105, n. 11, p. 3069, doi. 10.1002/jbm.a.36166
By:
- Córdova, Luis A.;
- Loi, Florence;
- Lin, Tzu‐Hua;
- Gibon, Emmanuel;
- Pajarinen, Jukka;
- Nabeshima, Akira;
- Lu, Laura;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Orthopaedic wear particle-induced bone loss and exogenous macrophage infiltration is mitigated by local infusion of NF-κB decoy oligodeoxynucleotide.
Published in:
Journal of Biomedical Materials Research, Part A, 2017, v. 105, n. 11, p. 3169, doi. 10.1002/jbm.a.36169
By:
- Lin, Tzuhua;
- Pajarinen, Jukka;
- Nabeshima, Akira;
- Córdova, Luis A.;
- Loi, Florence;
- Gibon, Emmanuel;
- Lu, Laura;
- Nathan, Karthik;
- Jämsen, Eemeli;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Mesenchymal stem cells in the aseptic loosening of total joint replacements.
Published in:
Journal of Biomedical Materials Research, Part A, 2017, v. 105, n. 4, p. 1195, doi. 10.1002/jbm.a.35978
By:
- Pajarinen, Jukka;
- Lin, Tzu‐hua;
- Nabeshima, Akira;
- Jämsen, Eemeli;
- Lu, Laura;
- Nathan, Karthik;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Correlations between macrophage polarizing cytokines, inflammatory mediators, osteoclast activity, and toll-like receptors in tissues around aseptically loosened hip implants.
Published in:
Journal of Biomedical Materials Research, Part A, 2017, v. 105, n. 2, p. 454, doi. 10.1002/jbm.a.35913
By:
- Jämsen, Eemeli;
- Kouri, Vesa‐Petteri;
- Ainola, Mari;
- Goodman, Stuart B.;
- Nordström, Dan C.;
- Eklund, Kari K.;
- Pajarinen, Jukka
Publication type:
Article
The effect of local IL-4 delivery or CCL2 blockade on implant fixation and bone structural properties in a mouse model of wear particle induced osteolysis.
Published in:
Journal of Biomedical Materials Research, Part A, 2016, v. 104, n. 9, p. 2255, doi. 10.1002/jbm.a.35759
By:
- Sato, Taishi;
- Pajarinen, Jukka;
- Behn, Anthony;
- Jiang, Xinyi;
- Lin, Tzu‐hua;
- Loi, Florence;
- Yao, Zhenyu;
- Egashira, Kensuke;
- Yang, Fan;
- Goodman, Stuart B.
Publication type:
Article
Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes.
Published in:
Journal of Biomedical Materials Research, Part A, 2016, v. 104, n. 2, p. 435, doi. 10.1002/jbm.a.35581
By:
- Naganuma, Yasushi;
- Takakubo, Yuya;
- Hirayama, Tomoyuki;
- Tamaki, Yasunobu;
- Pajarinen, Jukka;
- Sasaki, Kan;
- Goodman, Stuart B.;
- Takagi, Michiaki
Publication type:
Article
NF-κB decoy oligodeoxynucleotide inhibits wear particle-induced inflammation in a murine calvarial model.
Published in:
Journal of Biomedical Materials Research, Part A, 2015, v. 103, n. 12, p. 3872, doi. 10.1002/jbm.a.35532
By:
- Sato, Taishi;
- Pajarinen, Jukka;
- Lin, Tzu‐hua;
- Tamaki, Yasunobu;
- Loi, Florence;
- Egashira, Kensuke;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Modulation of mouse macrophage polarization in vitro using IL-4 delivery by osmotic pumps.
Published in:
Journal of Biomedical Materials Research, Part A, 2015, v. 103, n. 4, p. 1339, doi. 10.1002/jbm.a.35278
By:
- Pajarinen, Jukka;
- Tamaki, Yasunobu;
- Antonios, Joseph K.;
- Lin, Tzu‐Hua;
- Sato, Taishi;
- Yao, Zhenyu;
- Takagi, Michiaki;
- Konttinen, Yrjö T.;
- Goodman, Stuart B.
Publication type:
Article
Exposure of polyethylene particles induces interferon-γ expression in a natural killer T lymphocyte and dendritic cell coculture system in vitro: A preliminary study.
Published in:
Journal of Biomedical Materials Research, Part A, 2015, v. 103, n. 1, p. 71, doi. 10.1002/jbm.a.35159
By:
- Lin, Tzu‐Hua;
- Kao, Sunny;
- Sato, Taishi;
- Pajarinen, Jukka;
- Zhang, Ruth;
- Loi, Florence;
- Goodman, Stuart B.;
- Yao, Zhenyu
Publication type:
Article
Mutant monocyte chemoattractant protein 1 protein attenuates migration of and inflammatory cytokine release by macrophages exposed to orthopedic implant wear particles.
Published in:
Journal of Biomedical Materials Research, Part A, 2014, v. 102, n. 9, p. 3291, doi. 10.1002/jbm.a.34981
By:
- Yao, Zhenyu;
- Keeney, Michael;
- Lin, Tzu‐Hua;
- Pajarinen, Jukka;
- Barcay, Katherine;
- Waters, Heather;
- Egashira, Kensuke;
- Yang, Fan;
- Goodman, Stuart
Publication type:
Article
Macrophages-Key cells in the response to wear debris from joint replacements.
Published in:
Journal of Biomedical Materials Research, Part A, 2013, v. 101, n. 10, p. 3033, doi. 10.1002/jbm.a.34599
By:
- Nich, Christophe;
- Takakubo, Yuya;
- Pajarinen, Jukka;
- Ainola, Mari;
- Salem, Abdelhakim;
- Sillat, Tarvo;
- Rao, Allison J.;
- Raska, Milan;
- Tamaki, Yasunobu;
- Takagi, Michiaki;
- Konttinen, Yrjö T.;
- Goodman, Stuart B.;
- Gallo, Jiri
Publication type:
Article
Effect of Aging on the Macrophage Response to Titanium Particles.
Published in:
Journal of Orthopaedic Research, 2020, v. 38, n. 2, p. 405, doi. 10.1002/jor.24461
By:
- Jämsen, Eemeli;
- Pajarinen, Jukka;
- Lin, Tzu‐hua;
- Lo, Chi‐Wen;
- Nabeshima, Akira;
- Lu, Laura;
- Nathan, Karthik;
- Eklund, Kari K.;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Pro-inflammatory M1 macrophages promote Osteogenesis by mesenchymal stem cells via the COX-2-prostaglandin E2 pathway.
Published in:
Journal of Orthopaedic Research, 2017, v. 35, n. 11, p. 2378, doi. 10.1002/jor.23553
By:
- Lu, Laura Y.;
- Loi, Florence;
- Nathan, Karthik;
- Lin, Tzu‐hua;
- Pajarinen, Jukka;
- Gibon, Emmanuel;
- Nabeshima, Akira;
- Cordova, Luis;
- Jämsen, Eemeli;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Decreased osteogenesis in mesenchymal stem cells derived from the aged mouse is associated with enhanced NF-κB activity.
Published in:
Journal of Orthopaedic Research, 2017, v. 35, n. 2, p. 281, doi. 10.1002/jor.23270
By:
- Lin, Tzu‐hua;
- Gibon, Emmanuel;
- Loi, Florence;
- Pajarinen, Jukka;
- Córdova, Luis A.;
- Nabeshima, Akira;
- Lu, Laura;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Osteogenic ability of rat bone marrow concentrate is at least as efficacious as mesenchymal stem cells in vitro.
Published in:
Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2019, v. 107, n. 8, p. 2500, doi. 10.1002/jbm.b.34340
By:
- Kohno, Yusuke;
- Lin, Tzuhua;
- Pajarinen, Jukka;
- Romero‐Lopez, Monica;
- Maruyama, Masahiro;
- Huang, Jhih‐Fong;
- Nathan, Karthik;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Bone morphogenic protein expression and bone formation are induced by bioactive glass S53P4 scaffolds in vivo.
Published in:
Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2019, v. 107, n. 3, p. 847, doi. 10.1002/jbm.b.34181
By:
- Björkenheim, Robert;
- Strömberg, Gustav;
- Ainola, Mari;
- Uppstu, Peter;
- Aalto‐Setälä, Laura;
- Hupa, Leena;
- Pajarinen, Jukka;
- Lindfors, Nina C.
Publication type:
Article
The biological response to orthopaedic implants for joint replacement: Part I: Metals.
Published in:
Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2017, v. 105, n. 7, p. 2162, doi. 10.1002/jbm.b.33734
By:
- Gibon, Emmanuel;
- Amanatullah, Derek F.;
- Loi, Florence;
- Pajarinen, Jukka;
- Nabeshima, Akira;
- Yao, Zhenyu;
- Hamadouche, Moussa;
- Goodman, Stuart B.
Publication type:
Article
Interleukin‐4 repairs wear particle induced osteolysis by modulating macrophage polarization and bone turnover.
Published in:
Journal of Biomedical Materials Research, Part A, 2021, v. 109, n. 8, p. 1512, doi. 10.1002/jbm.a.37142
By:
- Pajarinen, Jukka;
- Lin, Tzuhua;
- Nabeshima, Akira;
- Sato, Taishi;
- Gibon, Emmanuel;
- Jämsen, Eemeli;
- Khan, Tahsin N.;
- Yao, Zhenyu;
- Goodman, Stuart B.
Publication type:
Article
Trained murine mesenchymal stem cells have anti-inflammatory effect on macrophages, but defective regulation on T-cell proliferation.
Published in:
FASEB Journal, 2019, v. 33, n. 3, p. 4203, doi. 10.1096/fj.201801845R
By:
- Tzuhua Lin;
- Pajarinen, Jukka;
- Yusuke Kohno;
- Jhih-Fong Huang;
- Masahiro Maruyama;
- Romero-Lopez, Monica;
- Nathan, Karthik;
- Zhenyu Yao;
- Goodman, Stuart B.
Publication type:
Article
Angiotensin receptor blockade mimics the effect of exercise on recovery after orthopaedic trauma by decreasing pain and improving muscle regeneration.
Published in:
Journal of Physiology, 2020, v. 598, n. 2, p. 317, doi. 10.1113/JP278991
By:
- Tawfik, Vivianne L.;
- Quarta, Marco;
- Paine, Patrick;
- Forman, Thomas E.;
- Pajarinen, Jukka;
- Takemura, Yoshinori;
- Goodman, Stuart B.;
- Rando, Thomas A.;
- Clark, J. David
Publication type:
Article
Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis.
Published in:
Stem Cell Research & Therapy, 2017, v. 8, p. 1, doi. 10.1186/s13287-017-0730-z
By:
- Tzuhua Lin;
- Pajarinen, Jukka;
- Nabeshima, Akira;
- Lu, Laura;
- Nathan, Karthik;
- Jämsen, Eemeli;
- Zhenyu Yao;
- Goodman, Stuart B.
Publication type:
Article
The effects of immunomodulation by macrophage subsets on osteogenesis in vitro.
Published in:
Stem Cell Research & Therapy, 2016, v. 7, p. 1, doi. 10.1186/s13287-016-0276-5
By:
- Loi, Florence;
- Córdova, Luis A.;
- Ruth Zhang;
- Pajarinen, Jukka;
- Tzu-hua Lin;
- Goodman, Stuart B.;
- Zhenyu Yao
Publication type:
Article
Particle disease really does exist: An evidence based rebuttal to Dr. Mjöberg's opinion letter.
Published in:
Acta Orthopaedica, 2018, v. 89, n. 1, p. 133, doi. 10.1080/17453674.2017.1402463
By:
- Pajarinen, Jukka;
- Gallo, Jiri;
- Takagi, Michiaki;
- Goodman, Stuart B;
- Mjöberg, Bengt
Publication type:
Article
Yrjö Tapio Konttinen 1952-2014.
Published in:
2015
By:
- Pajarinen, Jukka;
- Nordström, Dan;
- Petterson, Tom;
- Ainola, Mari;
- Gómez-Barrena, Enrique;
- Takagi, Michiaki;
- Goodman, Stuart B.
Publication type:
Journal Article
Yrjö Tapio Konttinen 1952-2014.
Published in:
Acta Orthopaedica, 2015, v. 86, n. 2, p. 145, doi. 10.3109/17453674.2015.1022103
By:
- Pajarinen, Jukka;
- Nordström, Dan;
- Petterson, Tom;
- Ainola, Mari;
- Gómez-Barrena, Enrique;
- Takagi, Michiaki;
- Goodman, Stuart B.
Publication type:
Article
Toll-like receptors in human chondrocytes and osteoarthritic cartilage.
Published in:
Acta Orthopaedica, 2013, v. 84, n. 6, p. 585, doi. 10.3109/17453674.2013.854666
By:
- Sillat, Tarvo;
- Barreto, Gonçalo;
- Clarijs, Paul;
- Soininen, Antti;
- Ainola, Mari;
- Pajarinen, Jukka;
- Korhonen, Matti;
- Konttinen, Yrjö T;
- Sakalyte, Regina;
- Hukkanen, Mika;
- Ylinen, Pekka;
- Nordström, Dan C E
Publication type:
Article
Chemokines Associated with Pathologic Responses to Orthopedic implant Debris.
Published in:
Frontiers in Endocrinology, 2017, v. 8, p. 1, doi. 10.3389/fendo.2017.00005
By:
- Hallab, Nadim J.;
- Jacobs, Joshua J.;
- Omar, Reviewed by:Omar;
- Pajarinen, Jukka
Publication type:
Article
Local delivery of mutant CCL2 protein-reduced orthopaedic implant wear particle-induced osteolysis and inflammation in vivo.
Published in:
Journal of Orthopaedic Research, 2016, v. 34, n. 1, p. 58, doi. 10.1002/jor.22977
By:
- Jiang, Xinyi;
- Sato, Taishi;
- Yao, Zhenyu;
- Keeney, Michael;
- Pajarinen, Jukka;
- Lin, Tzu‐hua;
- Loi, Florence;
- Egashira, Kensuke;
- Goodman, Stuart;
- Yang, Fan
Publication type:
Article
Characterization of macrophage polarizing cytokines in the aseptic loosening of total hip replacements.
Published in:
Journal of Orthopaedic Research, 2014, v. 32, n. 9, p. 1241, doi. 10.1002/jor.22658
By:
- Jämsen, Eemeli;
- Kouri, Vesa‐Petteri;
- Olkkonen, Juri;
- Cör, Andrej;
- Goodman, Stuart B.;
- Konttinen, Yrjö T.;
- Pajarinen, Jukka
Publication type:
Article
Toll-like receptors and aseptic loosening of hip endoprosthesis-a potential to respond against danger signals?
Published in:
Journal of Orthopaedic Research, 2010, v. 28, n. 2, p. 184, doi. 10.1002/jor.20979
By:
- Lähdeoja, Tuomas;
- Pajarinen, Jukka;
- Kouri, Vesa-Petteri;
- Sillat, Tarvo;
- Salo, Jari;
- Konttinen, Yrjö T.
Publication type:
Article
Cohort study on incidence of new-onset type 2 diabetes in patients after bariatric surgery and matched controls.
Published in:
British Journal of Surgery, 2024, v. 111, n. 4, p. 1, doi. 10.1093/bjs/znae105
By:
- Vahtera, Viiko;
- Pajarinen, Jukka;
- Kivimäki, Mika;
- Ervasti, Jenni;
- Pentti, Jaana;
- Stenholm, Sari;
- Vahtera, Jussi;
- Salminen, Paulina
Publication type:
Article

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